Search results for " TRAPS"
showing 10 items of 92 documents
Generation of Schrödinger Cats in Trapped Ions
2004
A quantum system in interaction with a repeatedly measured one is subjected to a non-unitary time evolution provoking the decay of some states in favor of the remaining ones. Under appropriate hypotheses the system may be addressed exactly toward a quantum state or pushed into a pre-selected finite-dimensional subspace. On the basis of such a general strategy, we propose to exploit suitable vibronic couplings in order to ‘extract’ trapped ion center of mass states of motion characterized by well defined absolute value of an angular momentum projection. In particular, since it implies the simultaneous presence of opposite angular momentum projections, we show the realizability of Schrödinger…
High-precision mass measurements for the rp-process at JYFLTRAP
2017
The double Penning trap JYFLTRAP at the University of Jyvaskyla has been successfully used to achieve high-precision mass measurements of nuclei involved in the rapid proton-capture (rp) process. A precise mass measurement of 31 Cl is essential to estimate the waiting point condition of 30 S in the rp-process occurring in type I x-ray bursts (XRBs). The mass-excess of 31 C1 measured at JYFLTRAP, -7034.7(3.4) keV, is 15 more precise than the value given in the Atomic Mass Evaluation 2012. The proton separation energy S p determined from the new mass-excess value confirmed that 30 S is a waiting point, with a lower-temperature limit of 0.44 GK. The mass of 52 Co effects both 51 Fe( p,γ ) 52 C…
Mass Measurement on the rp-Process Waiting Point 72Kr
2004
The mass of one of the three major waiting points in the astrophysical rp process $^{72}$Kr was measured for the first time with the Penning trap mass spectrometer ISOLTRAP. The measurement yielded a relative mass uncertainty of $\deltam/m = 1.2\times 10–7 (\deltam$ = 8 keV). $^{73,74}$Kr, also needed for astrophysical calculations, were measured with more than 1 order of magnitude improved accuracy. We use the ISOLTRAP masses of $^{72–74}$Kr to reanalyze the role of $^{72}$Kr (T$_{1/2}$ = 17.2 s) in the rp process during x-ray bursts and conclude that $^{72}$Kr is a strong waiting point delaying the burst duration with at least 80\% of its $\beta$-decay half-life.
Geometric Phase Accumulation-Based Effects in the Quantum Dynamics of an Anisotropically Trapped Ion
2005
New physical effects in the dynamics of an ion confined in an anisotropic two-dimensional Paul trap are reported. The link between the occurrence of such manifestations and the accumulation of geometric phase stemming from the intrinsic or controlled lack of symmetry in the trap is brought to light. The possibility of observing in laboratory these anisotropy-based phenomena is briefly discussed.
Microwave potentials and optimal control for robust quantum gates on an atom chip
2006
We propose a two-qubit collisional phase gate that can be implemented with available atom chip technology, and present a detailed theoretical analysis of its performance. The gate is based on earlier phase gate schemes, but uses a qubit state pair with an experimentally demonstrated, very long coherence lifetime. Microwave near-fields play a key role in our implementation as a means to realize the state-dependent potentials required for conditional dynamics. Quantum control algorithms are used to optimize gate performance. We employ circuit configurations that can be built with current fabrication processes, and extensively discuss the impact of technical noise and imperfections that charac…
Image charge shift in high-precision Penning traps
2019
An ion in a Penning trap induces image charges on the surfaces of the trap electrodes. These induced image charges are used to detect the ion's motional frequencies, but they also create an additional electric field, which shifts the free-space cyclotron frequency typically at a relative level of several ${10}^{\ensuremath{-}11}$. In various high-precision Penning-trap experiments, systematics and their uncertainties are dominated by this so-called image charge shift (ICS). The ICS is investigated in this work by a finite-element simulation and by a dedicated measurement technique. Theoretical and experimental results are in excellent agreement. The measurement is using singly stored ions a…
Neutrophil Extracellular Traps as a Drug Target to Counteract Chronic and Acute Inflammation
2019
Neutrophil extracellular traps (NET), extruded decondensated chromatin entangled with neutrophil proteases, have been first identified in neutrophils stimulated with bacteria or phorbol myristate acetate (PMA) via activation of NADPH oxidase and the generation of reactive oxygen species. Although the first findings demonstrated the beneficial role of NET formation by trapping the bacteria and limiting their dissemination, numerous studies in the recent decade revealed the multifunctional aspects of NET formation which manifests itself not only in the context of anti-microbial effect but also as a pathological trigger. Uncontrolled and exaggerated NET formation or inability to digest and rem…
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia
2021
Abstract SARS-CoV-2 vaccine ChAdOx1 nCoV-19 (AstraZeneca) causes a thromboembolic complication termed vaccine-induced immune thrombotic thrombocytopenia (VITT). Using biophysical techniques, mouse models, and analysis of VITT patient samples, we identified determinants of this vaccine-induced adverse reaction. Super-resolution microscopy visualized vaccine components forming antigenic complexes with platelet factor 4 (PF4) on platelet surfaces to which anti-PF4 antibodies obtained from VITT patients bound. PF4/vaccine complex formation was charge-driven and increased by addition of DNA. Proteomics identified substantial amounts of virus production-derived T-REx HEK293 proteins in the ethyle…
High-precision mass measurements and production of neutron-deficient isotopes using heavy-ion beams at IGISOL
2019
An upgraded ion-guide system for the production of neutron-deficient isotopes with heavy-ion beams has been commissioned at the IGISOL facility with an $^{36}\mathrm{Ar}$ beam on a $^{\mathrm{nat}}\mathrm{Ni}$ target. It was used together with the JYFLTRAP double Penning trap to measure the masses of $^{82}\mathrm{Zr}, ^{84}\mathrm{Nb}, ^{86}\mathrm{Mo}, ^{88}\mathrm{Tc}$, and $^{89}\mathrm{Ru}$ ground states and the isomeric state $^{88}\mathrm{Tc}^{m}$. Of these, $^{89}\mathrm{Ru}$ and $^{88}\mathrm{Tc}^{m}$ were measured for the first time. The precision of measurements of $^{82}\mathrm{Zr}, ^{84}\mathrm{Nb}$, and $^{88}\mathrm{Tc}$ was significantly improved. The literature value for $^…
SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities
2019
Myeloid-derived suppressor cells (MDSC) are well-known key negative regulators of the immune response during tumor growth, however scattered is the knowledge of their capacity to influence and adapt to the different tumor microenvironments and of the markers that identify those capacities. Here we show that the secreted protein acidic and rich in cysteine (SPARC) identifies in both human and mouse MDSC with immune suppressive capacity and pro-tumoral activities including the induction of epithelial-to-mesenchymal transition (EMT) and angiogenesis. In mice the genetic deletion of SPARC reduced MDSC immune suppression and reverted EMT. Sparc−/− MDSC were less suppressive overall and the granu…