Search results for " TRIM"

Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy

2019

Key Points Question Is exposure to ambient air pollution in the first trimester associated with thyroid function throughout pregnancy? Findings Among 9931 pregnant women in 4 European cohorts and 1 US cohort, an increase of 5 μg/m3 in exposure to particulate matter with an aerodynamic diameter of 2.5 μm or less was associated with 20% higher odds of hypothyroxinemia. Meaning The findings of this study raise the possibility that exposure to particulate matter might disrupt thyroid function in pregnant women.

Cytogenetic analyses of culture failures by comparative genomic hybridisation (CGH)–Re-evaluation of chromosome aberration rates in early spontaneous…

2001

Comparative genomic hybridisation (CGH) represents an alternative molecular-cytogenetic technique capable of detecting chromosomal imbalances by reverse fluorescence in situ hybridisation. As the technique uses genomic DNA for assessment it does not rely on metaphase chromosomes in the test material and thus circumvents technical problems associated with tissue culturing. In the present study, we applied CGH to identify chromosome anomalies in 60 spontaneous abortions of the first trimester, that had failed to grow in culture. In 57 out of 60 cases CGH analyses were successful. The overall aneuploidy rate detected was 72%. Trisomy was the predominant chromosome anomaly accounting for 68.0% …

Imbalance of expression of bFGF and PK1 is associated with defective maturation and antenatal placental insufficiency.

2013

Abstract Objective Defective placental maturation is associated with restricted functional capacity and adverse perinatal fetal outcomes. The aim of the study was a comparative analysis of the role of mRNA expression of various angiogenic factors in placental maturation defects. Study design We examined the mRNA expression patterns of prokineticin 1 (PK1), its receptors (PKRs), basic-fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) in tissue from third-trimester placentae that exhibited delayed or accelerated villous maturation. Results The expression of PK1 and PKR2 was elevated in placental tissue exhibiting accelerated maturati…

Factors influencing caries status and treatment needs among pregnant women attending a maternity hospital in Udaipur city, India.

2012

To estimate the prevalence and severity of dental caries along with the treatment needs; to determine the factors that influence dental caries status among pregnant women attending a district maternity hospital in Udaipur, India. Study design: Study sample comprised of 206 pregnant women attending a district maternity hospital in Udaipur, India. Clinical data were collected on dental caries by DMFT and treatment needs as described in World Health Organization Dentition status and Treatment needs. Results: The overall caries prevalence was 87%. Mean caries experience differed significantly among women in various trimesters, it was found to be 3.59 and 3.00 in 1st and 2nd trimester subjects r…

First-trimester reversed end-diastolic flow in the umbilical artery is not always an ominous sign

2003

We report five cases of first-trimester reversed end-diastolic flow in the umbilical artery. Diagnoses were performed between 8 and 12 gestational weeks. All but one case appeared as a transient early finding. Second-trimester fetal demise occurred in two cases. One case delivered at 32 weeks with severe growth restriction but recovered well. The other two cases had a good pregnancy outcome. Our experience suggests that this early Doppler finding is not always an ominous sign.

Vēsture: Latvijas Universitātes Žurnāls, 2018, Nr.5

2018

On-line in-tube solid phase microextraction coupled to capillary liquid chromatography-diode array detection for the analysis of caffeine and its met…

2019

Abstract In-tube solid phase microextraction (IT-SPME) coupled on-line to capillary liquid chromatography with diode array detection provides a simple and fast analytical methodology for the simultaneous quantitation of caffeine and its three primary metabolites (theobromine, paraxanthine and theophylline) in micro samples of serum, saliva and urine matrices. The sample amount required for one analysis was only 2.5 μL of saliva, 6.25 μL of serum or 40 μL of urine, a requirement for its implementation in a hospital laboratory for preterm newborns, where sample availability is a major problem. In standard conditions, 25 μL of diluted saliva or serum (or 100 μL of urine) were processed by IT-S…

Riso, potere e modelli letterari nella Coena Trimalchionis

2022

Il contributo mira ad esaminare i riferimenti al fenomeno della risata nel contesto della Coena Trimalchionis, narrata ai capp. 27-78 del Satyricon petroniano. Le occasioni di riso che si vengono a creare nel corso della cena presso il ricco liberto – contesto in cui il dislivello sociale e culturale tra i personaggi di scuola ed gli indocti è costantemente sottoposto all’attenzione del lettore – evidenziano infatti una forte distorsione delle dinamiche di potere in ambito conviviale. L’atteggiamento di scherno nei confronti dei liberti da parte degli scholastici, spesso costretti a trattenere l’ilarità di fronte alle trovate ed ai discorsi dalla profonda bassezza culturale di Trimalchione …

Iteratively reweighted least squares in crystal structure refinements

2011

The use of robust techniques in crystal structure multipole refinements of small molecules as an alternative to the commonly adopted weighted least squares is presented and discussed. As is well known, the main disadvantage of least-squares fitting is its sensitivity to outliers. The elimination from the data set of the most aberrant reflections (due to both experimental errors and incompleteness of the model) is an effective practice that could yield satisfactory results, but it is often complicated in the presence of a great number of bad data points, whose one-by-one elimination could become unattainable. This problem can be circumvented by means of a robust least-squares regression that…

CCDC 2057074: Experimental Crystal Structure Determination

2021

Related Article: Maciej Bujak, Hans-Georg Stammler, Yury V. Vishnevskiy, Norbert W. Mitzel|2022|CrystEngComm|24|70|doi:10.1039/D1CE01268A