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RESEARCH PRODUCT
Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy
Adonina TardónHenning TiemeierHenning TiemeierSheryl L. Rifas-shimanMaria-josé Lopez-espinosaTessa A. MulderMartine VrijheidJordi JulvezRobin P. PeetersJordi SunyerMònica GuxensTanja G. M. VrijkotteAitana LertxundiTim I M KorevaarEuripides G. StephanouEmily OkenLivia PierottiMikel BasterrecheaPolyxeni KarakostaPolyxeni KarakostaDiane R. GoldDiane R. GoldMarisa EstarlichLeda ChatziLeda ChatziAbby F. FleischAkhgar GhassabianAna Fernández-somoanosubject
PhysiologyThyrotropin010501 environmental sciences01 natural sciencesCohort Studies0302 clinical medicinePregnancy030212 general & internal medicineOriginal Investigationbiologymedicine.diagnostic_testAmbient air pollutionThyroidGeneral Medicine3. Good healthOnline Onlymedicine.anatomical_structureHypothyroxinemiaCohortGeneration RFemaleThyroid functionEnvironmental HealthAdultendocrine systemNitrogen DioxideThyroid function testsIodide Peroxidase03 medical and health sciencesYoung AdultThyroid peroxidaseEnvironmental healthAir PollutionmedicineHumansParticle Size0105 earth and related environmental sciencesAutoantibodiesPregnancybusiness.industryResearchEnvironmental Exposuremedicine.diseaseThyroid DiseasesPregnancy Trimester FirstThyroxine13. Climate actionbiology.proteinParticulate Matterbusinessdescription
Key Points Question Is exposure to ambient air pollution in the first trimester associated with thyroid function throughout pregnancy? Findings Among 9931 pregnant women in 4 European cohorts and 1 US cohort, an increase of 5 μg/m3 in exposure to particulate matter with an aerodynamic diameter of 2.5 μm or less was associated with 20% higher odds of hypothyroxinemia. Meaning The findings of this study raise the possibility that exposure to particulate matter might disrupt thyroid function in pregnant women.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-10-17 | JAMA network open |