0000000000353313

AUTHOR

Akhgar Ghassabian

0000-0001-9551-4706

showing 4 related works from this author

Air Pollution Exposure During Pregnancy and Symptoms of Attention Deficit and Hyperactivity Disorder in Children in Europe

2018

Background: Exposure to air pollution during pregnancy may increase attention-deficit/hyperactivity disorder (ADHD) symptoms in children, but findings have been inconsistent. We aimed to study this association in a collaborative study of eight European population-based birth/child cohorts, including 29,127 mother-child pairs. Methods: Air pollution concentrations (nitrogen dioxide [NO2] and particulate matter [PM]) were estimated at the birth address by land-use regression models based on monitoring campaigns performed between 2008 and 2011. We extrapolated concentrations back in time to exact pregnancy periods. Teachers or parents assessed ADHD symptoms at 3-10 years of age. We classified …

Pediatricsmedicine.medical_specialtyEpidemiologyNitrogen DioxideEnvironmental pollution010501 environmental sciences01 natural sciencesOdds03 medical and health sciences0302 clinical medicinePregnancyAir PollutionmedicineHumanslongitudinal studies030212 general & internal medicineChildProspective cohort study0105 earth and related environmental scienceschild developmentparticulate matterInhalation ExposurePregnancybusiness.industryattention deficit disorder with hyperactivityOdds ratiomedicine.diseaseChild developmentConfidence intervalprospective studies3. Good healthEuropemeta-analysisnitrogen oxidesChild PreschoolPrenatal Exposure Delayed EffectsMeta-analysisFemaleenvironmental pollutionAttention Deficit Disorder With Hyperactivity ; Child Development ; Environmental Pollution ; Longitudinal Studies ; Meta-analysis ; Nitrogen Oxides ; Particulate Matter ; Prospective Studiesbusiness
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Air Pollution During Pregnancy and Childhood Cognitive and Psychomotor Development: Six European Birth Cohorts

2014

Background: Accumulating evidence from laboratory animal and human studies suggests that air pollution exposure during pregnancy affects cognitive and psychomotor development in childhood. Methods: We analyzed data from 6 European population-based birth cohorts-GENERATI ON R (The Netherlands), DUISBURG (Germany), EDEN (France), GASPII (Italy), RHEA (Greece), and INMA (Spain)-that recruited mother-infant pairs from 1997 to 2008. Air pollution levels-nitrogen oxides (NO2, NOx) in all regions and particulate matter (PM) with diameters of <2.5, <10, and 2.5-10 mu m (PM2.5, PM10, and PMcoarse, respectively) and PM2.5 absorbance in a subgroup-at birth addresses were estimated by land-use regressi…

MaleEpidemiologyDevelopmental DisabilitiesAir pollutionCHILDRENmedicine.disease_causeCohort StudiesChild DevelopmentCognitionPregnancyCognitive developmentProspective StudiesChildSDG 15 - Life on LandPsychomotor learningAir PollutantsDIESEL EXHAUSTBIRTH COHORTEuropeMaternal ExposureChild PreschoolPrenatal Exposure Delayed EffectsINFANT NEURODEVELOPMENTFemaleNitrogen OxidesPROJECTCohort studyEnvironmental MonitoringAdultmedicine.medical_specialtyPOLYCYCLIC AROMATIC-HYDROCARBONSAGESDG 3 - Good Health and Well-beingEnvironmental healthAir PollutionmedicineHumansPRENATAL EXPOSUREPollutantPregnancyCOAL-BURNING POLLUTANTSbusiness.industryPublic healthLOCOMOTOR-ACTIVITYInfantModels Theoreticalmedicine.diseaseConfidence intervalLinear ModelsParticulate MatterbusinessPsychomotor PerformanceEpidemiology
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Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy

2019

Key Points Question Is exposure to ambient air pollution in the first trimester associated with thyroid function throughout pregnancy? Findings Among 9931 pregnant women in 4 European cohorts and 1 US cohort, an increase of 5 μg/m3 in exposure to particulate matter with an aerodynamic diameter of 2.5 μm or less was associated with 20% higher odds of hypothyroxinemia. Meaning The findings of this study raise the possibility that exposure to particulate matter might disrupt thyroid function in pregnant women.

PhysiologyThyrotropin010501 environmental sciences01 natural sciencesCohort Studies0302 clinical medicinePregnancy030212 general & internal medicineOriginal Investigationbiologymedicine.diagnostic_testAmbient air pollutionThyroidGeneral Medicine3. Good healthOnline Onlymedicine.anatomical_structureHypothyroxinemiaCohortGeneration RFemaleThyroid functionEnvironmental HealthAdultendocrine systemNitrogen DioxideThyroid function testsIodide Peroxidase03 medical and health sciencesYoung AdultThyroid peroxidaseEnvironmental healthAir PollutionmedicineHumansParticle Size0105 earth and related environmental sciencesAutoantibodiesPregnancybusiness.industryResearchEnvironmental Exposuremedicine.diseaseThyroid DiseasesPregnancy Trimester FirstThyroxine13. Climate actionbiology.proteinParticulate MatterbusinessJAMA network open
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Air pollution exposure during pregnancy and childhood autistic traits in four European population-based cohort studies: The ESCAPE Project

2015

Background: Prenatal exposure to air pollutants has been suggested as a possible etiologic factor for the occurrence of autism spectrum disorder. Objectives: We aimed to assess whether prenatal air pollution exposure is associated with childhood autistic traits in the general population. Methods: Ours was a collaborative study of four European population-based birth/child cohorts—CATSS (Sweden), Generation R (the Netherlands), GASPII (Italy), and INMA (Spain). Nitrogen oxides (NO2, NOx) and particulate matter (PM) with diameters of ≤ 2.5 μm (PM2.5), ≤ 10 μm (PM10), and between 2.5 and 10 μm (PMcoarse), and PM2.5 absorbance were estimated for birth addresses by land-use regression models bas…

medicine.medical_specialtyInfants -- Malaltiesnitrogen oxideHealth Toxicology and MutagenesisAir pollution exposureeducation05 Environmental Sciencesair pollutionAir pollutionautismprenatal exposuremedicine.disease_causeToxicologysmokingAire -- Contaminació -- EspanyaEnvironmental healthMedicinePsychiatryPregnancybusiness.industrychildhood diseasePublic Health Environmental and Occupational HealthEuropean population11 Medical And Health Sciencesmedicine.disease3. Good healthPeer reviewAutistic traits13. Climate actionChildren's HealthAutismpregnancybusinessCohort study
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