Search results for " Ti"

showing 10 items of 10180 documents

Accountability for disinformation in times of covid-19

2022

Nelabvēlīgās informācijas plašais tvērums liek vairumam sabiedrībā ar vien uzmanīgāk vērtēt informāciju sociālajos tīklos un masu mēdijos, bet arī nekritiski domājošā sabiedrības daļa ir jāpasargā no šādas bīstamas informācijas it īpaši globālās pandēmijas laikā, kad plašie pamattiesību ierobežojumi un ikdienas saasinājumi vājina uzticību valdībai. It īpaši nelabvēlīgas informācijas izplatīšanas ierobežojumi ir nepieciešama virtuālajā vidē, jo 21. gs. ir pavēris jaunas iespējas daļēji vai pilnīgi nepatiesas informācijas ātrai izplatīšanai. Pašlaik Latvijā nav skaidri izveidota doktrīna, kā efektīvi aizsargāt nelabvēlīgās informācijas aizskartās cilvēktiesības, jo to traucē plašais aizsardzī…

virtuālā telpanacionālās tiesībasstarptautiskā praksevārda brīvībanelabvēlīga informācijaJuridiskā zinātne
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Additional file 2: Figure S1. of The genetic architecture of low-temperature adaptation in the wine yeast Saccharomyces cerevisiae

2017

Distribution of private nonsynonymous SNPs in P5 and P24 compared to S288c. An external circle indicates P24 and an internal circle indicates P5. Homozygous changes are colored in green, while heterozygous changes are marked in red. (PDF 243 kb)

virus diseasessense organsskin and connective tissue diseases
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Transfection of lipoma cells with papilloma bovine virus subgenomic fragment.

1991

Abstract Lipoma cells with consistent chromosomal aberration have been transfected with plasmids carrying papilloma bovine virus subgenomic fragment (PBV 69). The succesful transformation of the cells was ascerted on the changed growth pattern of the cells in liquid medium, colony formation in soft agar and modified cell appearrance in electron microscopy; transfection with PBV 69 has not been, however, sufficient to immortalize lipoma cells.

virusesCellEndoplasmic ReticulumTransfectionVirusPlasmidotorhinolaryngologic diseasesmedicineTumor Cells CulturedHumansBovine papillomavirusSubgenomic mRNABovine papillomavirus 1Cell Line TransformedChromosome AberrationsbiologyMusclesCell DifferentiationCell BiologyTransfectionFibroblastsbiology.organism_classificationmedicine.diseaseCell Transformation ViralVirologyClone CellsMicroscopy Electronmedicine.anatomical_structureAdipose TissueCell culturePapillomaLipomaCell DivisionCell biology international reports
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Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations.

2021

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents the most severe global health crisis in modern human history. One of the major SARS-CoV-2 virulence factors is nonstructural protein 1 (Nsp1), which, outcompeting with the binding of host mRNA to the human ribosome, triggers a translation shutdown of the host immune system. Here, microsecond-long all-atom simulations of the C-terminal portion of the SARS-CoV-2/SARS-CoV Nsp1 in complex with the 40S ribosome disclose that SARS-CoV-2 Nsp1 has evolved from its SARS-CoV ortholog to more effectively hijack the ribosome by undergoing a critical switch of Q/E158 and E/Q159 residues that perfects Nsp1's interactions…

virusesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirulenceBiologyMolecular Dynamics SimulationViral Nonstructural ProteinsRibosomeImmune systemHumansGeneral Materials ScienceEukaryotic Small Ribosomal SubunitPhysical and Theoretical Chemistryskin and connective tissue diseasesRibosome Subunits Small EukaryoticMessenger RNANSP1SARS-CoV-2fungivirus diseasesCOVID-19Translation (biology)Hydrogen BondingCell biologybody regionsSettore CHIM/03 - Chimica Generale E InorganicaProtein BindingThe journal of physical chemistry letters
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Theoretical and experimental analysis of viscoelastic behavior of biomaterials

2014

viscoelasticity Timoshenko beam biomaterials
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The ALICE experiment at the CERN LHC

2008

Journal of Instrumentation 3(08), S08002 (2008). doi:10.1088/1748-0221/3/08/S08002

visible and IR photonsLiquid detectorshigh energyPhotonPhysics::Instrumentation and DetectorsTransition radiation detectorsTiming detectors01 natural sciencesOverall mechanics designParticle identificationSoftware architecturesParticle identification methodsGaseous detectorscluster findingDetector cooling and thermo-stabilizationDetector groundingParticle tracking detectors[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Special cablesDetector alignment and calibration methodsDetectors and Experimental TechniquesNuclear ExperimentVoltage distributions.Photon detectors for UVInstrumentationMathematical PhysicsQuantum chromodynamicsPhysicsLarge Hadron ColliderSpectrometersPhysicsDetectorcalibration and fitting methodsTransition radiation detectorScintillatorsData processing methodsAnalysis and statistical methodsData reduction methodsParticle physicsCherenkov and transition radiationTime projection chambers610dE/dx detectorsNuclear physicsCalorimetersPattern recognitionGamma detectors0103 physical sciencesddc:610Solid state detectors010306 general physicsMuonInstrumentation for heavy-ion acceleratorsSpectrometerLarge detector systems for particle and astroparticle physics010308 nuclear & particles physicsCERN; LHC; ALICE; heavy ion; QGPCherenkov detectorsComputingVoltage distributionsManufacturingscintillation and light emission processesanalysis and statistical methods; calorimeters; cherenkov and transition radiation; cherenkov detectors; computing; data processing methods; data reduction methods; de/dx detectors; detector alignment and calibration methods; detector cooling and thermo-stabilization; detector design and construction technologies and materials; detector grounding; gamma detectors; gaseous detectors; instrumentation for heavy-ion accelerators; instrumentation for particle accelerators and storage rings - high energy; large detector systems for particle and astroparticle physics; liquid detectors; manufacturing; overall mechanics design; particle identification methods; particle tracking detectors; pattern recognition; cluster finding; calibration and fitting methods; photon detectors for uv; visible and ir photons; scintillators; scintillation and light emission processes; simulation methods and programs; software architectures; solid state detectors; special cables; spectrometers; time projection chambers; timing detectors; transition radiation detectors; voltage distributionsInstrumentation for particle accelerators and storage ringsInstrumentation; Mathematical PhysicsHigh Energy Physics::ExperimentSimulation methods and programsDetector design and construction technologies and materials
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Vispārinātie lineārie modeļi skaita tipa datu analīzei

2022

Bakalaura darbs ir veltīts vispārināto lineāro modeļu, kas piemēroti skaita tipa datu analīzei, teorijas apskatam. Darbā apskatīts Puasona regresijas modelis, kā arī modeļi, kas piemēroti pārāk lielas dispersijas gadījumā (kvazi-Puasona un negatīvā binomiālā sadalījuma regresijas modeļi). Skaita tipa datos var būt situācijas, kad liels datu daudzums ir 0, tāpēc šādu datu analīzei aprakstīti īpaši piemēroti modeļi, jo iepriekšminētie modeļi šādiem datiem nevar sniegt korektus novērtējumus. Atsevišķi tika aprakstīta arī empīriskās ticamības funkcijas metode vispārināto lineāro modeļu koeficientu novērtēšanai un ticamības intervālu konstruēšanai, kuru var izmantot Puasona modeļa gadījumā. Darb…

vispārinātie lineārie modeļiMatemātikaPuasona regresijaGLMnegatīvā binomiālā regresijaskaita tipa dati
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Käsitettävä taidehistoria : kuvalähtöinen malli taidehistorian opetukseen kuvallisen ilmaisun ammatillisessa perustutkinnossa

2011

visual artvisual literacytiedonkäsitystacit knowledgeopetusteachingKvalitatiivinen tutkimushiljainen tietokuvataidekonstruktivismididaktiikkaart historyconstructivismdidacticstaidehistoriakuvallinen ilmaisu
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Impacts of Touch Screen Size, User Interface Design, and Subtask Boundaries on In-Car Task's Visual Demand and Driver Distraction

2020

Visual distraction by secondary in-car tasks is a major contributing factor in traffic incidents. In-car user interface design may mitigate these negative effects but to accomplish this, design factors’ visual distraction potential should be better understood. The effects of touch screen size, user interface design, and subtask boundaries on in-car task's visual demand and visual distraction potential were studied in two driving simulator experiments with 48 participants. Multilevel modeling was utilized to control the visual demands of driving and individual differences on in-car glance durations. The 2.5” larger touch screen slightly decreased the in-car glance durations and had a diminis…

visual distractionComputer scienceihmisen ja tietokoneen vuorovaikutusHuman Factors and ErgonomicsEducationTask (project management)subtask boundarykäyttöliittymätHuman–computer interactionDistraction0502 economics and business0501 psychology and cognitive sciencesautotekniikka050107 human factorskosketusnäyttö050210 logistics & transportation05 social sciencesGeneral EngineeringDriving simulatorvisual demandnäköUser interface designHuman-Computer Interactionmultilevel modelDisplay sizeHardware and Architecturekatseenseurantain-vehicle user interfaceSoftwarevisual occlusion
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Explicit behavioral detection of visual changes develops without their implicit neurophysiological detectability

2011

Change blindness is a failure of reporting major changes across consecutive images if separated, e.g., by a brief blank interval. Successful change detection across interrupts requires focal attention to the changes. However, findings of implicit detection of visual changes during change blindness have raised the question of whether the implicit mode is necessary for development of the explicit mode. To this end, we recorded the visual mismatch negativity (vMMN) of the event-related potentials (ERPs) of the brain, an index of implicit pre-attentive visual change detection, in adult humans performing an oddball-variant of change blindness flicker task. Images of 500 ms in duration were prese…

visual mismatch negativitygenetic structuresflicker paradigmMismatch negativityStimulus (physiology)Electroencephalographyevent-related potentialsBlanklcsh:RC321-571Developmental psychologyBehavioral NeuroscienceEvent-related potentialInter-stimulus intervalmedicineOriginal Research Articleskin and connective tissue diseaseslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOddball paradigmta515Biological Psychiatrychange blindnessmedicine.diagnostic_testPsychiatry and Mental healthNeuropsychology and Physiological PsychologyNeurologyChange blindnesssense organsPsychologyChange detectionNeuroscienceoddball paradigmCognitive psychologyFrontiers in Human Neuroscience
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