Search results for " Tradition"
showing 10 items of 360 documents
Pharmacological and chemical features ofNepetaL. genus: Its importance as a therapeutic agent
2017
Medicinal plants have always had great value for the human population due to their valuable constituents and potential bioactivities. The objective of this review is to present an updated overview of an important medicinal plant genus Nepeta L., from the family Lamiaceae, revealing its traditional utilization, biological activity, phytoconstituents, and mechanisms of action. For this purpose, a literature survey was carried out by using SciFinder, ScienceDirect, Scopus, PubMed, and Web of Science followed by a revision of the bibliographies of the related articles. We have described and analyzed the role of plants in drug discovery and the importance of Nepeta species. Information on the ut…
Filozofia polityczna Tomasza Hobbesa i jej wpływ na ukształtowanie się moderności
2017
Considered one of the greatest and most original English philosophers, Thomas Hobbes was the founder of modern political philosophy. His modernity manifests itself in a revolutionary position – in emphasizing novelty and in completely breaking with the past. We are still influenced by his ideas. He has introduced the model of the human being, who is driven by his desires and is involved in the ongoing activity of multiplying his wealth and of acquiring more and more power, and of the state as the organization of coercion. The knowledge of Hobbes’s political thought is essential to understand the ideological foundations of the modern world, as well as to creatively overcome them.
Saying the Saffu and Beating the Law: The Changing Role of Sacred Sites in the Oromo Politico-Juridical System
2013
This chapter presents a semiotic analysis of the role of sacred sites and other physical features and objects in key political/religious rituals of the Oromo people living in the Horn of Africa. Theoretically, it builds on Jacques Derrida’s deconstruction of the concept of ‘archive’ as an intersection of the topological and the nomological of the place and the law. For Derrida, the place of the archive is not a locatable place, but a topos, the marking of a discourse. In contrast to the European tradition based primarily on archives inscribed in writing and summarised in a codified law, for the traditional Oromo society, laws were part of the oral tradition – a mixture of religion, law and …
Latvijas Universitātes 95 mirkļi
2014
Latvijas Universitātes 95. gadadienai veltīts izdevums. -- The edition dedicated to the 95th anniversary of the University of Latvia
Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.
2012
AbstractOmic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of omic techniques is crucial for understanding and interpretation of TCM development, especially in view of its expansion in Western countries. In this short review, omic applications in TCM research are reviewed which has allowed some speculation regarding future perspectives for these approaches in TCM modernisation and standardisation. Guidelines for good practice for …
Toxicogenomics for the prediction of toxicity related to herbs from traditional Chinese medicine.
2010
Toxicogenomics represents the integration of genomics and toxicology to investigate the interaction between genes and environmental stress in human health. It is a scientific field that studies how the genome is involved in responses to environmental stressors and toxicants. The patterns of altered gene expression that are caused by specific exposures or disease outcomes reveal how toxicants may act and cause disease. Nowadays, toxicogenomics faces great challenges in discriminating the molecular basis of toxicity. We do believe that advances in this field will eventually allow us to describe all the toxicological interactions that occur within a living system. Toxicogenomic responses of a …
Review of current and “omics” methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms
2012
Ethnopharmacological relevance: The increasing use of traditional herbal medicines around the world requires more scientific evidence for their putative harmlessness. To this end, a plethora of methods exist, more or less satisfying. In this post-genome era, recent reviews are however scarce, not only on the use of new "omics" methods (transcriptomics, proteomics, metabonomics) for genotoxicity, teratogenicity, and nephrotoxicity assessment, but also on conventional ones. Methods: The present work aims (i) to review conventional methods used to assess genotoxicity, teratogenicity and nephrotoxicity of medicinal plants and mushrooms; (ii) to report recent progress in the use of "omics" techn…
Transgresión moral y enfermedad en los países nórdicos en la temprana Edad Moderna
2009
This article seeks to understand how people in the early modern age interpreted the nature of illness and the role that morality played in these interpretations. From this point of view illnesses were not only psycho-physical states or subjects for medical diagnosis but they were also subjects for narratives or stories through which people tried to understand what had caused their illness, and why it was happening to them. Illnesses were understood as strictly connected with the patient's character and were regarded as possible consequences of his personality. On the other hand, the interpretations also emphasised the ambivalence of a healer. Personal experiences and an understanding of one…
Elderly Parents’ Need for Help and Adult Children's Moving Decisions
2015
Recent changes in Finnish welfare policies have increased the need for family involvement in eldercare. This article uses qualitative interviews to study working adult daughters’ reasons for moving in with their parent(s). Coresidence was linked to the parents’ need for support, but also to the daughters’ life situations, family histories, the availability of welfare services, and cultural norms and values. The interviewees used the “familist” and “independent life” discourses in their speech. The familist discourse was used to argue for coresidence as a natural continuation of family traditions and life history, whereas the independent life discourse was used to legitimize the need for alt…
The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells
2011
Targeting synthetic lethality in DNA repair pathways has become a promising anti-cancer strategy. However little is known about such interactions with regard to the nucleotide excision repair (NER) pathway. Therefore, cell lines with a defect in the NER genes ERCC6 or XPC and their normal counterparts were screened with 53 chemically defined phytochemicals isolated from plants used in traditional Chinese medicine for differential cytotoxic effects. The screening revealed 12 drugs that killed NER-deficient cells more efficiently than proficient cells. Five drugs were further analyzed for IC50 values, effects on cell cycle distribution, and induction of DNA damage. Ascaridol was the most effe…