Search results for " Transplants"
showing 7 items of 17 documents
An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients.
2009
OBJECTIVES: Caspofungin was evaluated as first-line monotherapy of invasive aspergillosis (IA) in patients with haematological malignancies and undergoing autologous transplants. METHODS: Adults with proven or probable IA, defined strictly according to EORTC-MSG criteria, were eligible. Those with possible IA were enrolled, but were not evaluable for efficacy unless upgraded to proven/probable disease within 7 days of registration based on investigations performed within 48 h after enrolment. Caspofungin dosage was 70 mg (day 1) followed by 50 mg/day. The primary endpoint was the proportion of patients with complete or partial response at the end of caspofungin therapy in the modified inten…
New Interpretative Scales for Lichen Bioaccumulation Data: The Italian Proposal
2019
The interpretation of lichen bioaccumulation data is of paramount importance in environmental forensics and decision-making processes. By implementing basic ideas underlying previous interpretative scales, new dimensionless, species-independent &ldquo
Outcomes of Donor-Recipient Gender Mismatched Lung Transplantation in the Eurotransplant Area
2019
Purpose An effect of donor-recipient gender mismatching on long-term survival outcomes following organ transplantation has been postulated but remains controversial. We aimed to investigate the influence of gender mismatches on long-term survival after lung transplantation in the Eurotransplant area. Methods In this retrospective, multicentre study in the Eurotransplant area, all lung transplants performed from DBD lungs in the period from 01.01.2000 until 31.12.2015 were included. A total of 7688 lung transplant recipients (≥ 14 years old) for long-term survival and the effect of gender mismatches (Kaplan-Meier, multivariate regression). Results More men (4079; 52 %) were transplanted comp…
Recensione di G. Giaimo, La volontà e il corpo, Giappichelli, Torino, 2019, pp. 224
2021
Il contributo recensisce il volume di G. Giaimo, La volontà e il corpo, Torino, 2019, mettendo in evidenza i diversi temi trattati e l'approccio dell'analisi. The contribution reviews the volume by G. Giaimo, La volontà e il corpo, Turin, 2019, highlighting the different themes dealt with and the analysis approach.
The ‘margin of appreciation’ in echr case-law as a boundary line to legal transplants
2015
This study investigates the influence of the European Human Rights Court on State 'margin of appreciation' on the diffusion of accepted or rejected cultural and political choices through the jurisprudence of the case-law. The margin of appreciation is aninterpretative argument, a criterion, a parameter, which allows the Court to preserve rather than censure national State policies and choices on difficult issues which, involving moral and ethical questions, and which do not receive common answers in the ,European legal systems. The work considers some decisions of the Court on abortion, ovum donation, pre-implant embryo analysis and artificial procreation techniques, to find out if, in such…
Takrolimus w długoterminowym leczeniu immunosupresyjnym biorców przeszczepu nerki — praktyczne wskazówki
2020
Tacrolimus got the position crucial immunosuppressive drug in a solid organ transplantation. For obtaining the best long-term results it is essential an avoidance of excessive dose lowering and maintenance stable drug concentration. The intrapatient tacrolimus concentration variability, which exerts negative impact on the graft survival, should be differentiated from fluctuation, describing distinct pharmacokinetic event, without proven clinical significance. Furthermore, real tacrolimus concentration variability should be separated from variability caused by recipient instability. Among causes of tacrolimus intrapatient variability on the first places are: insufficient adherence to treatme…
PRODUZIONE DI RIFIUTI A RISCHIO INFETTIVO E INDICI DI COMPLESSITÀ IN UN “CENTRO TRAPIANTI”
2015
Questo studio analizza la produzione di rifiuti a rischio infettivo in una grande struttura ospedaliera specializzata per le attività di trapianto: Ismett (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), che si trova a Palermo. Sono state determinate le relazioni fra la quantità e la composizione dei rifiuti, da una parte; la complessità della struttura e la natura delle cure erogate, dall’altra. In letteratura si trovano regolarmente i risultati di ricerche sulla produzione di rifiuti a rischio infettivo nei più diversi Paesi del mondo; i dati pubblicati provengono quasi esclusivamente da Ospedali Generali, anche complessi e di Alta Specializzazione. Tali dati po…