Search results for " Treatment Outcome"

showing 10 items of 288 documents

Palliative sedation in advanced cancer patients followed at home: A retrospective analysis

2012

Abstract CONTEXT: Data regarding palliative sedation at home in dying patients are lacking. OBJECTIVES: To describe the frequency, indication, and modality of palliative sedation (PS) in patients followed at home. METHODS: A retrospective analysis of home care cancer patients was performed. Patients who received PS before dying were selected and information about epidemiologic characteristics, indications, duration, drugs, and outcomes was collected. RESULTS: Of 370 medical charts of patients who died at home, 49 patients received PS before dying. PS was proposed by the team, relatives, or both in 63.3%, 4.1%, and 32.6% of cases, respectively. Delirium alone or in combination with other sym…

end of lifeMalePediatricsmedicine.medical_specialtyPalliative carePainComorbiditySettore MED/42 - Igiene Generale E ApplicataPalliative sedationadvanced cancer patientPalliative sedationRisk FactorsNeoplasmsRETROSPECTIVE STUDYPrevalenceMedicineHumansHypnotics and SedativesPALLIATIVE SEDATION; advanced cancer patients; RETROSPECTIVE STUDYIntensive care medicineSurvival rateGeneral NursingSurvival analysisNursing (all)2901 Nursing (miscellaneous)Retrospective StudiesTerminal Carepalliative carebusiness.industryDeliriumRetrospective cohort studymedicine.diseaseComorbidityHome Care ServicesSurvival AnalysisSurvival RateTreatment OutcomeAnesthesiology and Pain MedicineItalyend of life; home care; palliative care; Palliative sedation; Comorbidity; Delirium; Female; Home Care Services; Humans; Hypnotics and Sedatives; Italy; Male; Neoplasms; Pain; Palliative Care; Prevalence; Retrospective Studies; Risk Factors; Survival Analysis; Survival Rate; Terminal Care; Treatment Outcome; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)MidazolamDeliriumFemaleNeurology (clinical)medicine.symptombusinesshome caremedicine.drug
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Palliative sedation in patients with advanced cancer followed at home: A systematic review

2011

Abstract Context Patients with advanced cancer who are near the end of life may experience intolerable suffering refractory to targeted palliative therapies. Palliative sedation (PS) is considered to be an effective treatment modality for these refractory symptoms when aggressive efforts fail to provide relief. Objectives The aim of this study was to systematically review articles regarding PS performed at home in patients with intractable symptoms. Methods Literature databases searched included MedLine, PubMed, and EMBASE. The text words and MeSH/EMTREE terms "home care" and "sedation" were used for electronic database searches. Results Six articles met the inclusion criteria for research …

end of lifemedicine.medical_specialtyPalliative careSedationMEDLINEPainContext (language use)Palliative sedationend of life; home care; Palliative sedation; Clinical Trials as Topic; Delirium; Dyspnea; Home Care Services; Humans; Hypnotics and Sedatives; Neoplasms; Pain; Retrospective Studies; Treatment Outcome; Palliative Care; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)NeoplasmsmedicineHumansHypnotics and SedativesIntensive care medicineProspective cohort studyGeneral NursingNursing (all)2901 Nursing (miscellaneous)Retrospective StudiesClinical Trials as Topicbusiness.industryPalliative CareDeliriumRetrospective cohort studyHome Care ServicesDyspneaTreatment OutcomeAnesthesiology and Pain MedicineMeta-analysisMidazolamNeurology (clinical)medicine.symptombusinesshome caremedicine.drug
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Could infertility related stress and anxiety of both partners influence women's ovarian response to stimulation during ICSI treatment?

2012

infertility stress anxiety treatment outcomeSettore M-PSI/08 - Psicologia Clinica
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Improving adherence in osteoporosis: a new management algorithm for the patient with osteoporosis

2011

Introduction: Bisphosphonates are the first-choice treatment for osteoporosis. They effectively increase bone mineral density, reduce markers of bone resorption, and lower the incidence of new fractures in patients with osteoporosis-related fracture. However, the efficacy observed in clinical trials may not be realized in a real-life setting, partly due to poor adherence to therapy, with a significant worsening of clinical outcomes. Several issues contribute to poor adherence to osteoporosis medication, including inconvenient dosing regimens and concerns about possible adverse events. Although strategies to improve adherence have been investigated, new approaches are required. Areas covered…

medicine.medical_specialtyBone Density Conservation AgentBone densityOsteoporosisAlternative medicineadherence; osteoporosis; treatment algorithm; bone density; medication possession ratio; bisphosphonatesMedication AdherenceClinical ProtocolsCost of IllnessTreatment algorithmmedicineHumansBisphosphonatePharmacology (medical)DosingClinical ProtocolAdverse effectMED/01 - STATISTICA MEDICAOsteoporosis PostmenopausalAdherence bisphosphonates bone density medication possession ratio osteoporosis treatment algorithmMedication possession ratioPharmacologyBone Density Conservation Agentsbusiness.industryOsteoporosiGeneral Medicinemedicine.diseaseAlgorithmCost of IllneClinical trialBone Density Conservation AgentsTreatment OutcomeZoledronic acidAdherenceAdherence; Bisphosphonates; Bone density; Medication possession ratio; Osteoporosis; Treatment algorithm; Algorithms; Bone Density Conservation Agents; Clinical Protocols; Cost of Illness; Female; Humans; Osteoporosis; Osteoporosis Postmenopausal; Treatment Outcome; Medication Adherence; Pharmacology; Pharmacology (medical)Physical therapyOsteoporosisFemaleBone densitybusinessAlgorithmsHumanmedicine.drugExpert Opinion on Pharmacotherapy
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Italian association for the study of the liver position statement on SARS-CoV2 vaccination.

2021

The vaccination campaign against Sars-CoV-2 commenced in Italy at the end of December 2020. The first ones to receive the immunization against the virus were the health workers and the residents of nursing homes, following which the vaccine would be available for the entire population, beginning with the most vulnerable individuals. SARS-CoV2 vaccines have been demonstrated to be safe for the general population, although no data for patients with liver diseases or those having undergone liver transplantation are available so far. The present position statement AISF is an attempt to suggest, based on the published data on the impact of Sars-Cov-2 infection in patients with chronic liver dise…

medicine.medical_specialtyCOVID-19 VaccinesSars-CoV-2medicine.medical_treatmentPopulationLiver transplantationChronic liver diseaseRisk AssessmentPatient safetyEpidemiologyMedicineChronic liver disease Sars-CoV-2 Vaccination Humans Immunosuppressive Agents Italy Liver Transplantation Patient Safety Patient Selection Risk Adjustment Risk Assessment SARS-CoV-2 Transplant Recipients Treatment Outcome COVID-19 COVID-19 Vaccines Immunization Programs Liver DiseasesHumanseducationeducation.field_of_studyHepatologybusiness.industryImmunization ProgramsLiver DiseasesPatient SelectionChronic liver disease; Sars-CoV-2; VaccinationVaccinationChronic liver diseaseGastroenterologyCOVID-19medicine.diseaseTransplant RecipientsLiver TransplantationVaccinationTreatment OutcomeImmunizationItalyFamily medicineChronic liver disease; Sars-CoV-2; Vaccination; Humans; Immunosuppressive Agents; Italy; Liver Transplantation; Patient Safety; Patient Selection; Risk Adjustment; Risk Assessment; SARS-CoV-2; Transplant Recipients; Treatment Outcome; COVID-19; COVID-19 Vaccines; Immunization Programs; Liver DiseasesRisk AdjustmentPatient SafetyPosition PaperbusinessRisk assessmentImmunosuppressive AgentsDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Fluticasone propionate/formoterol: a fixed-combination therapy with flexible dosage.

2014

International guidelines describe asthma control as the main outcome of asthma management. Prevention of symptoms, improved quality of life, and reduction of exacerbations are the main components, consequently decreasing health care costs. However, many of these objectives remain unmet in real life: several surveys show that a large proportion of asthmatic patients are not well controlled despite the efficacy of current available treatment. Several randomized controlled clinical trials indicate that combining inhaled corticosteroids and long-acting β2-agonists, by means of a single inhaler, greatly improves the management of the disease. The results of 9 multicenter phase III clinical studi…

medicine.medical_specialtyCombination therapyAsthma exacerbationSettore MED/10 - Malattie dell'Apparato RespiratorioSettore MED/10 - Malattie Dell'Apparato RespiratorioFluticasone propionateAsthma control; Asthma exacerbations; Fixed-combination therapy; Fluticasone propionate/formoterol; Single-aerosol inhalerAsthma controlFluticasone propionate/formoterolForced Expiratory VolumeFormoterol FumarateInternal MedicineMedicineHumansAnti-Asthmatic AgentsAsthma exacerbationsParticle SizeIntensive care medicineAsthmaFluticasonebusiness.industryInhalerNebulizers and VaporizersFixed-combination therapyAsthma control; Asthma exacerbations; Fixed-combination therapy; Fluticasone propionate/formoterol; Single-aerosol inhaler; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Drug Combinations; Ethanolamines; Fluticasone; Forced Expiratory Volume; Formoterol Fumarate; Humans; Nebulizers and Vaporizers; Particle Size; Quality of Life; Treatment Outcomemedicine.diseaseSingle-aerosol inhalerAsthmaBronchodilator AgentsAndrostadienesDrug CombinationsTreatment OutcomeTolerabilityAsthma control Asthma exacerbations Fixed-combination therapy Fluticasone propionate/formoterol Single-aerosol inhalerEthanolaminesAnesthesiaAsthma exacerbations; Asthma control; Fixed-combination therapy; Fluticasone propionate/formoterol; Single-aerosol inhalerQuality of LifeFluticasoneFormoterol FumarateFormoterolbusinessmedicine.drugEuropean journal of internal medicine
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Preoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis

2004

Background: The benefit of neoadjuvant chemoradiotherapy in oesophageal cancer has been extensively studied but data on survival are still equivocal. Objective: To assess the effectiveness of chemoradiotherapy followed by surgery in the reduction of mortality in patients with resectable oesophageal cancer. Methods: Computerised bibliographic searches of MEDLINE and CANCERLIT (1970–2002) were supplemented with hand searches of reference lists. Study selection: Studies were included if they were randomised controlled trials (RCTs) comparing preoperative chemoradiotherapy plus surgery with surgery alone, and if they included patients with resectable histologically proven oesophageal cancer wit…

medicine.medical_specialtyEsophageal Neoplasmsmedicine.medical_treatmentlaw.inventionPostoperative ComplicationsRandomized controlled triallawChemotherapyHumansMedicineEsophageal NeoplasmAdjuvantRandomized Controlled Trials as TopicIntention-to-treat analysisRadiotherapybusiness.industryMortality rateGastroenterologyCancerOdds ratiomedicine.diseaseChemotherapy Adjuvant; Esophageal Neoplasms; Esophagectomy; Humans; Postoperative Complications; Radiotherapy Adjuvant; Randomized Controlled Trials; Survival Analysis; Treatment OutcomeSurvival AnalysisSurgeryEsophagectomyRadiation therapyOesophagusTreatment OutcomeChemotherapy AdjuvantEsophagectomyRandomized Controlled TrialChemotherapy; Adjuvant; Esophageal Neoplasms; Esophagectomy; Humans; Postoperative Complications; Radiotherapy; Randomized Controlled Trials as Topic; Survival Analysis; Treatment OutcomeRadiotherapy AdjuvantPostoperative ComplicationSurvival AnalysibusinessChemoradiotherapyHumanGut
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Clinical evaluation and treatment of acute asthma exacerbations in children

2009

This update on treatment of asthma exacerbations in children is the result of an Italian Pediatric Society Task-force, made up of a panel of experts working in 2007–2008. The aim is to give clear indications on the use of the drugs most employed in children, grading the quality of evidence and the strength of recommendations. Suggestions on their limits due to unlicensed and off-label use are reported. The level of evidence and the strength of recommendations for different therapeutic approaches demonstrate that frequently the use of drugs in children is extrapolated from the experience in adults and that more studies are required to endorse the correct use of different drugs in asthmatic …

medicine.medical_specialtyImmunologyMEDLINESeverity of Illness Index; Acute Disease; Evidence-Based Medicine; Off-Label Use; Hospitalization; Humans; Treatment Outcome; Practice Guidelines as Topic; Asthma; Anti-Asthmatic Agents; Child; Child PreschoolOff-label useSeverity of Illness IndexSeverity of illnessHumansAnti-Asthmatic AgentImmunology and AllergyMedicineAnti-Asthmatic AgentsChildIntensive care medicineGrading (education)PharmacologyEvidence-Based MedicineAsthma exacerbationsbusiness.industryOff-Label UseEvidence-based medicineAsthmaHospitalizationQuality of evidenceacute asthma; children; emergency treatmentTreatment OutcomeSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAChild PreschoolAcute DiseasePractice Guidelines as Topicacute asthma exacerbations in childrenbusinessacute asthma exacerbations in children.Clinical evaluationHuman
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Transperitoneal vs retroperitoneal minimally invasive partial nephrectomy: comparison of perioperative outcomes and functional follow-up in a large m…

2020

Abstract Background Aim of this study was to evaluate and compare perioperative outcomes of transperitoneal (TP) and retroperitoneal (TR) approaches in a multi-institutional cohort of minimally invasive partial nephrectomy (MI-PN). Material and methods All consecutive patients undergone MI-PN for clinical T1 renal tumors at 26 Italian centers (RECORd2 project) between 01/2013 and 12/2016 were evaluated, collecting the pre-, intra-, and postoperative data. The patients were then stratified according to the surgical approach, TP or RP. A 1:1 propensity score (PS) matching was performed to obtain homogeneous cohorts, considering the age, gender, baseline eGFR, surgical indication, clinical dia…

medicine.medical_specialtyIntraoperative ComplicationUrologymedicine.medical_treatmentOperative TimeSurgical approach030232 urology & nephrologyMinimally invasive partial nephrectomy Renal cell carcinoma Retroperitoneal Surgical approach Transperitoneal.lcsh:RC870-923lcsh:RC254-282NephrectomyArticle03 medical and health sciences0302 clinical medicineRenal cell carcinomamedicineMinimally invasive partial nephrectomy; Renal cell carcinoma; Retroperitoneal; Surgical approach; TransperitonealHumansRetroperitoneal SpaceRetrospective StudiesMinimally invasive partial nephrectomybusiness.industryRenal cell carcinoma; Minimally invasive partial nephrectomy; Transperitoneal; Retroperitoneal; Surgical approachTransperitonealPerioperativeRetroperitoneallcsh:Diseases of the genitourinary system. Urologylcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseNephrectomyKidney NeoplasmsRenal cell carcinomaSurgerySettore MED/24Treatment Outcome030220 oncology & carcinogenesisPropensity score matchingCohortSurgeryLaparoscopyPositive Surgical MarginMinimally invasive partial nephrectomy; Renal cell carcinoma; Retroperitoneal; Surgical approach; Transperitoneal; Follow-Up Studies; Humans; Nephrectomy; Operative Time; Retroperitoneal Space; Retrospective Studies; Treatment Outcome; Kidney Neoplasms; LaparoscopybusinessAbdominal surgeryFollow-Up StudiesSurgical endoscopy
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Nutrition and acne: therapeutic potential of ketogenic diets.

2011

The influence of nutrition on skin health is a growing research area but the findings of various studies on the effect of diet on the development of acne have often been contradictory. The general opinion among researchers has oscillated between two different, opposing positions: that diet either is or is not a key factor for acne development. This review examines the evidence supporting an influence of various dietary components on the development of acne particularly focusing on the role played by carbohydrates. The physiological and biochemical effects of the ketogenic diet are examined from this perspective and mechanisms will be proposed via which this type of diet could have a role in…

medicine.medical_specialtyKetogenicPhysiologymedicine.medical_treatmentTreatment outcomePhysiologyNutritional StatusDermatologyInternal medicineAcne VulgarismedicineDietary CarbohydratesHumansAcnePharmacologyEvidence-Based Medicinebusiness.industryNutritional statusGeneral MedicineEvidence-based medicineKetosisNutrition Acne Ketogenic Dietmedicine.diseaseDietEndocrinologyTreatment OutcomeKetosisbusinessAcne Vulgaris; Dietary Carbohydrates; Evidence-Based Medicine; Humans; Ketosis; Nutritional Status; Treatment Outcome; Diet KetogenicDiet KetogenicKetogenic dietSkin pharmacology and physiology
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