Search results for " VALIDATION"
showing 10 items of 313 documents
Derivation and validation of a novel bleeding risk score for elderly patients with venous thromboembolism on extended anticoagulation
2017
SummaryExisting clinical scores do not perform well in predicting bleeding in elderly patients with acute venous thromboembolism (VTE). We sought to derive an easy-to-use clinical score to help physicians identify elderly patients with VTE who are at high-risk of bleeding during extended anticoagulation (>3 months). Our derivation sample included 743 patients aged ≥65 years with VTE who were enrolled in a prospective multicenter cohort study. All patients received extended anticoagulation with vitamin K antagonists. We derived our score using competing risk regression, with the time to a first major bleeding up to 36 months of extended anticoagulation as the outcome, and 17 candidate var…
Predicting survival after transarterial chemoembolization for hepatocellular carcinoma using a neural network: A Pilot Study.
2019
BACKGROUND AND AIMS Deciding when to repeat and when to stop transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC) can be difficult even for experienced investigators. Our aim was to develop a survival prediction model for such patients undergoing TACE using novel machine learning algorithms and to compare it to conventional prediction scores, ART, ABCR and SNACOR. METHODS For this retrospective analysis, 282 patients who underwent TACE for HCC at our tertiary referral centre between January 2005 and December 2017 were included in the final analysis. We built an artificial neural network (ANN) including all parameters used by the aforementioned risk scores a…
Prospective external validation of a predictive score for postoperative pulmonary complications.
2015
Abstract Background: No externally validated risk score for postoperative pulmonary complications (PPCs) is currently available. The authors tested the generalizability of the Assess Respiratory Risk in Surgical Patients in Catalonia risk score for PPCs in a large European cohort (Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe). Methods: Sixty-three centers recruited 5,859 surgical patients receiving general, neuraxial, or plexus block anesthesia. The Assess Respiratory Risk in Surgical Patients in Catalonia factors (age, preoperative arterial oxygen saturation in air, acute respiratory infection during the previous month, preoperative anemia, upp…
<p>Translation, validation, and cross-cultural adaptation of the Polish version of the pain sensitivity questionnaire</p>
2019
Introduction The purpose of this study was to provide a translation, cross-cultural adaptation, and validation of the Polish language version of the pain sensitivity questionnaire (PSQ). The process followed widely accepted guidelines. Methods The translated questionnaire underwent thorough psychometric testing. In total, the data of 144 subjects (mean age 52.53±13 years), who underwent evaluation for lower back pain, were included. Results The exploratory factor analysis revealed a two-factor structure, PSQ-moderate and PSQ-minor. The internal consistency was good (Cronbach's α was 0.96). There was a fair and significant correlation between the results of the PSQ and the coping strategy qu…
Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes
2014
Objective The purpose of this study was to evaluate the contamination rate of media-fill products either prepared automated with a robotic system (APOTECAchemo™) or prepared manually at cytotoxic workbenches in the same cleanroom environment and by experienced operators. Media fills were completed by microbiological environmental control in the critical zones and used to validate the cleaning and disinfection procedures of the robotic system. Methods The aseptic preparation of patient individual ready-to-use injection solutions was simulated by using double concentrated tryptic soy broth as growth medium, water for injection and plastic syringes as primary packaging materials. Media fills w…
An EEMD Aided Comparison of Time Histories and Its Application in Vehicle Safety
2017
In the context of signal processing, the comparison of time histories is required for different purposes, especially for the model validation of vehicle safety. Most of the existing metrics focus on the mathematical value only. Therefore, they suffer the measuring errors, disturbance, and uncertainties and can hardly achieve a stable result with a clear physical interpretation. This paper proposes a novel scheme of time histories comparison to be used in vehicle safety analysis. More specifically, each signal for comparison is decomposed into a trend signal and several intrinsic mode functions (IMFs) by ensemble empirical mode decomposition. The trend signals reflect the general variation a…
Factor selection procedures in a Google Earthtm aided landslide susceptibility model: application to the Beiro river basin (Spain)
2011
A procedure to select the controlling factors connected to the slope instability has been defined. It allowed to assess the landslide susceptibility in the Rio Beiro basin (about 10 km2) over the north-eastern area of the city of Granada (Spain). Field and remote (Google EarthTM) recognition techniques allowed to generate a landslide inventory consisting in 127 phenomena. Univariate tests, using both association coefficients and validation results of single parameter susceptibility models, allowed to select among 15 controlling factors the ones that resulted as good predictor variables; these have been combined for unique conditions analysis and susceptibility maps were finally prepared. In…
Community detection of seismic point processes
2022
In this paper, we combine robin and Local Indicators of Spatio-Temporal Association (LISTA) functions. robin is an R package to assess the robustness of the community structure of a network found by one or more methods to give indications about their reliability. We use it to propose a classification algorithm of events in a spatio-temporal point pattern, by means of the local second-order characteristics and the community detection procedure in network analysis. We demonstrate the proposed procedure on a real data analysis on seismic data.
Development of fast analysis methods for extractives in papermaking process waters
2011
A fast analysis method with an online sample enrichment technique for the analysis of resin and fatty acids present in papermaking process waters was developed. This method was based on atmospheric pressure chemical ionization (APCI) and mass spectrometry (MS) for the detection of [M-H]- ions of compounds of interest. The method was applied to the control of the most prevalent resin (dehydroabietic and abietic) and fatty (palmitic, stearic, oleic, and linolenic) acid levels in papermaking process waters. Continuous data on these acids are of practical importance when predicting possible deposit-derived problems in the paper machine. The first part of the study was focused on the development…
Logical Intelligence Enhancement Test: a measure for the evaluation of logical skills in primary school
2019
Il presente lavoro si inserisce in uno studio pilota condotto nell’anno scolastico 2018-2019per valutare l’efficacia del Logical Intelligence Enhancement Programme (LIEP, Calvani, Peru,& Zanaboni, 2019), un programma composto da tavole di logica verbale e numerica volte asviluppare il ragionamento logico e le capacità metacognitive di studenti di quinta primaria.All’interno di questo studio è stato sviluppato il Logical Intelligence Enhancement test perstimare gli effetti del training sulle abilità logico-verbali. Il contributo presenta la costru-zione del test, le sue caratteristiche psicometriche e la validazione. A tal fine, lo strumentoè stato somministrato a un campione di 173 stud…