Search results for " Variation"
showing 10 items of 1712 documents
Intra- and Interrater Reliability of Sagittal Spinopelvic Parameters on Full-Spine Radiographs in Adults With Symptomatic Spinal Disorders
2018
Background/Aims To evaluate the intra- and interrater reliability (I-IR) of sagittal spinopelvic parameters from digital full-spine plain radiographs with basic software tools in an unselected adult population with degenerative spinal complaints who were evaluated for surgery. Methods Forty-nine adult full-spine digital radiographs were measured twice by 3 independent observers, including an experienced spine surgeon, an experienced radiologist, and a resident orthopedic surgeon. Clinical picture archiving and communication system workstations and software tools were used and landmarks were set manually. The I-IR of the sagittal vertical axis (SVA), pelvic tilt (PT), pelvic incidence (PI), …
Intérêts du phénotypage de la personnalité pour améliorer la lutte biologique : cas d’étude chez l’auxiliaire Trichogramma evanescens
2021
One promising approach to improve the use of biological control agents (BCA) consists in the exploitation of intraspecific variation on traits related to mass-rearing or field performance. Consistent inter-individual variations in behaviour (known as personality) have never been considered in biological control (BC) while they have proved to be heritable and correlated to phenotypic traits possibly related to fitness in rearing or field conditions. The aim of this PhD thesis was (i) to develop an experimental design to measure personality traits in a the egg-parasitoid Trichogramma evanescens, and (ii) to evaluate the feasibility and interest of phenotyping personality traits to set and imp…
The Variational Mcshane Integral in Locally Convex Spaces
2009
The variational McShane integral for functions taking values in a locally convex space is defined, and it is characterized by means of the p-variation of the indefinite Pettis integral
A CHARACTERIZATION OF THE WEAK RADON–NIKODÝM PROPERTY BY FINITELY ADDITIVE INTERVAL FUNCTIONS
2009
AbstractA characterization of Banach spaces possessing the weak Radon–Nikodým property is given in terms of finitely additive interval functions. Due to that characterization several Banach space valued set functions that are only finitely additive can be represented as integrals.
Radon-Nikodym derivatives of finitely additive interval measures taking values in a Banach space with basis
2011
Let X be a Banach space with a Schauder basis {en}, and let Φ(I)= ∑n en ∫I fn(t)dt be a finitely additive interval measure on the unit interval [0, 1], where the integrals are taken in the sense of Henstock–Kurzweil. Necessary and sufficient conditions are given for Φ to be the indefinite integral of a Henstock–Kurzweil–Pettis (or Henstock, or variational Henstock) integrable function f:[0, 1] → X.
Differentiation of an additive interval measure with values in a conjugate Banach space
2014
We present a complete characterization of finitely additive interval measures with values in conjugate Banach spaces which can be represented as Henstock-Kurzweil-Gelfand integrals. If the range space has the weak Radon-Nikodým property (WRNP), then we precisely describe when these integrals are in fact Henstock-Kurzweil-Pettis integrals.
Taking Advantage of Viral Immune Evasion: Virus-Derived Proteins Represent Novel Biopharmaceuticals
2006
In healthy individuals, natural and adaptive immune responses are able to control virus entry into the host. In particular, CD8(+)-mediated cytotoxicity, sustained by the intervention of CD4+ cells, represents the major key event leading to virus eradication. On the other hand, viruses are able to evade from host immune response via several mechanisms, and special emphasis will be placed on hepatitis C virus and chronic Epstein-Barr infections also in view of personal data. Virokines, viroreceptors, and serpins greatly contribute to viral immune escape, and, among virokines, interleukin (IL)-10 has been object of intensive studies. Finally, all these products have been used as biopharmaceut…
Association study of affective disorders with genetic polymorphisms of monoamine oxidases
2000
Introduction: Monoamine oxidases (MAO) catalyze the oxidative deamination of monoamines like norepinephrine, serotonin and dopamine. The existing MAOs (A and B) have distinct although partially overlapping biological functions and distributions in the brain. MAO A is mainly expressed in catecholaminergic neurons. Thirty-fold differences in enzyme activity of MAO A can be found in cultured cells from different individuals suggesting a genetic determination of enzyme activity. Indeed, a point mutation in the coding region of the gene which creates a restriction site for Fnu4HI alters the activity. Moreover, the pharmacological inhibition of monoamine oxidase A activity is one of the most effe…
Development of a nomogram for the estimation of long-term adherence to clozapine therapy using neutrophil fluorescence
2018
Aims: Previously, we have reported an association between clozapine use and elevated FL3 neutrophil fluorescence, a flow-cytometric parameter for cell viability. Here, we developed and evaluated a pharmacokinetic-pharmacodynamic model relating FL3-fluorescence to clozapine exposure and derived a nomogram for estimation of long-term adherence. Methods: Data from 27 patients initiating clozapine were analysed using nonlinear mixed effects modelling. A previously described pharmacokinetic model for clozapine was coupled to a FL3 fluorescence model. For this, an effect compartment with clozapine concentrations as input and a first order decay rate as output was linked with an Emax model to FL3-…
Bet-hedging in diapausing egg hatching of temporary rotifer populations - A review of models and new insights
2014
Habitat unpredictability is a local adaptation factor shaping life-history traits in rotifer populations. It may select for the evolution of bet-hedging through risk-spreading strategies in diapausing egg hatching. This means that a fraction of diapausing eggs in wild populations do not hatch even when the conditions are favorable for population growth. Thus, there is a remaining fraction of viable diapausing eggs standing in the sediments for longer periods. According to theory, it is expected that the incidence of bet-hedging strategies for diapausing egg hatching will be higher in more uncertain habitats. Here, we review the major predictions derived from theoretical models applied to th…