Search results for " Variation"

showing 10 items of 1712 documents

An evaluation of the microscopical counting methods of the tape in hirst-burkard pollen and spore trap

1981

Abstract Three different sampling units in current use and different sampling strategies were tested. Randomly placed microscope fields are good in estimating the daily mean concentration, but very big sample size is needed. Traverses across the slide in systematic order are best to estimate the shortterm concentrations and diurnal variation. A formula for the estimation of the error in one transverse traverse is given. Twelve transverse traverses in systematic order is also enough to estimate the daily mean concentration. One or two traverses along the length of the slide give often unreliable estimates because of the irregularities in the transverse variation of the particle concentration…

TraverseDiurnal temperature variationSampling (statistics)Plant ScienceTrap (plumbing)Biologymedicine.disease_causeGeodesyTransverse planeBetula pollenSample size determinationPollenmedicineEcology Evolution Behavior and SystematicsGrana
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Oxidative stress induces distinct physiological responses in the two Trebouxia phycobionts of the lichen Ramalina farinacea

2010

† Background and Aims Most lichens form associations with Trebouxia phycobionts and some of them simultaneously include genetically different algal lineages. In other symbiotic systems involving algae (e.g. reef corals), the relative abundances of different endosymbiotic algal clades may change over time. This process seems to provide a mechanism allowing the organism to respond to environmental stress. A similar mechanism may operate in lichens with more than one algal lineage, likewise protecting them against environmental stresses. Here, the physiological responses to oxidative stress of two distinct Trebouxia phycobionts (provisionally named TR1 and TR9) that coexist within the lichen R…

TrebouxiaAntioxidantLichensmedicine.medical_treatmentGlutathione reductasePlant ScienceGenes PlantPhotosynthesismedicine.disease_causeRamalina farinaceaSuperoxide dismutaseChlorophytaBotanyBenzene DerivativesmedicineHSP70 Heat-Shock ProteinsPhotosynthesisChlorophyll fluorescencebiologySuperoxide DismutaseGenetic VariationOriginal Articlesbiology.organism_classificationOxidative StressGlutathione ReductaseBiochemistrybiology.proteinOxidative stressAnnals of Botany
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The genetic structure of the cosmopolitan three-partner lichenRamalina farinaceaevidences the concerted diversification of symbionts

2012

The epiphytic lichen Ramalina farinacea is distributed throughout the northern hemisphere in which the same two algal Trebouxia species (provisionally named TR1 and TR9) coexist in every thallus. Ramalina farinacea symbionts were characterized based on the two fungal nuclear loci (nrITS and rpb2 ) along with the primary and secondary structures of nrITS from each Trebouxia species in the Iberian Peninsula and Canary Islands. The results indicated a noticeable genetic differentiation between mycobionts from these two geographic areas and also suggested concerted changes in the three partners of a lichen symbiosis toward two clearly distinguishable ‘holobiont’ lineages. Modeling of ITS2 RNA s…

TrebouxiaGenotypeLichensApplied Microbiology and BiotechnologyMicrobiologyRamalina farinaceaAscomycotaChlorophytaRamalinaBotanySymbiosisLichenPhylogenyEcologybiologyEcologyGenetic Variationbiology.organism_classificationThallusEuropeHolobiontRNA RibosomalSpainGenetic structureNucleic Acid ConformationEpiphyteFEMS Microbiology Ecology
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Fuzzified Tree Search in Real Domain Games

2011

Fuzzified game tree search algorithm is based on the idea that the exact game tree evaluation is not required to find the best move. Therefore, pruning techniques may be applied earlier resulting in faster search and greater performance. Applied to an abstract domain, it outperforms the existing ones such as Alpha-Beta, PVS, Negascout, NegaC*, SSS*/ Dual* and MTD(f). In this paper we present experimental results in real domain games, where the proposed algorithm demonstrated 10 percent performance increase over the existing algorithms.

Tree (data structure)Search algorithmPrincipal variation searchMonte Carlo tree searchPruning (decision trees)Alpha–beta pruningGame treeIterative deepening depth-first searchAlgorithmMathematics
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African trypanosomes expressing multiple VSGs are rapidly eliminated by the host immune system

2019

Significance Many parasites escape the host immune system by undergoing antigenic variation, a process in which surface antigens are regularly shed and replaced by new ones. Trypanosoma brucei employs multiple sophisticated molecular mechanisms to ensure the expression of a homogeneous VSG coat. We generated a mutant parasite that expresses multiple distinct VSGs and studied the consequences of having a multi-VSG coat during an infection. We showed that expression of multiple VSGs makes the parasites more vulnerable to the immune response, which can now control the trypanosomes from the onset of the infection, allowing most mice to survive. In the future, trypanosome infections may be treat…

Trypanosoma brucei bruceiParasitemiaBiologyTrypanosoma bruceiParasitemiaMicrobiologyHost-Parasite InteractionsMice03 medical and health sciencesImmune systemRAG2HMGB Proteinsparasitic diseasesmedicineAnimalsTrypanosoma brucei030304 developmental biologychemistry.chemical_classification0303 health sciencesMultidisciplinarymonoallelic expressionTDP1030306 microbiologyBiological Sciencesbiology.organism_classificationAcquired immune systemmedicine.diseaseAntigenic VariationVirologyadaptive immune response3. Good healthChromatinTrypanosomiasis AfricanPNAS PluschemistryImmune SystemGlycoproteinTrypanosomiasisVariant Surface Glycoproteins Trypanosomavariant surface glycoproteinProceedings of the National Academy of Sciences
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A 4500 year record of palaeomagnetic secular variation and relative palaeointensity from the Tyrrhenian Sea

2020

A marine sediment core from the western Mediterranean provides a newhigh-resolution 4,500-year record of palaeomagnetic secular variation and relativepalaeointensity. In 2013, the 7.1-metre C5 core was recovered from the TyrrhenianSea as part of the NextData climate data project. The coring site, 15 km offshorefrom the Volturno river mouth, is well-located to record combined marine andterrestrial palaeoclimatic influences, and the fine-grained, rapidly deposited sedimentsare effective palaeomagnetic recorders. We investigate the palaeomagnetic field direction and strength recorded in the core, which provide a valuable high-resolution recordof Holocene geomagnetic variation in the area. Usin…

Tyrrhenian Seapalaeomagnetic010504 meteorology & atmospheric sciencesGeologyOcean Engineering010502 geochemistry & geophysics01 natural sciencesSecular variationPaleontologysecular variationGeology0105 earth and related environmental sciencesWater Science and TechnologyGeological Society, London, Special Publications
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Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

2014

European Community Recent years have seen considerable progress in epidemiological and molecular genetic research into environmental and genetic factors in schizophrenia, but methodological uncertainties remain with regard to validating environmental exposures, and the population risk conferred by individual molecular genetic variants is small. There are now also a limited number of studies that have investigated molecular genetic candidate gene-environment interactions (G x E), however, so far, thorough replication of findings is rare and G x E research still faces several conceptual and methodological challenges. in this article, we aim to review these recent developments and illustrate h…

URBANICITYSchizophrenia (object-oriented programming)CHILDHOODGenome-wide association studyVARIANTSSocial Environmentpsychosi03 medical and health sciences0302 clinical medicinePSYCHOSISepidemiology; gene-environment interaction; genetics; psychosis; schizophreniaSDG 3 - Good Health and Well-beingRISK-FACTORSettore M-PSI/08 - Psicologia ClinicaGenetic variationHumansGenetic Predisposition to DiseasegeneticspsychosisGENOME-WIDE ASSOCIATIONGeneSettore MED/25 - PsichiatriaMETAANALYSISScale (chemistry)schizophrenia; gene-environment interaction; Psychosis; epidemiology; geneticsGenetic variantsEnvironment and Schizophrenia InvitedCANNABIS USE3. Good health030227 psychiatrygene-environment interactionschizophreniaPsychiatry and Mental healthEvolutionary biology/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingIdentification (biology)Schizophrenic PsychologyepidemiologyPopulation RiskgeneticPsychologyFOLLOW-UP030217 neurology & neurosurgeryFUTURE-DIRECTIONSClinical psychology
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Solutions to the 1-harmonic flow with values into a hyper-octant of the N-sphere

2013

Abstract We announce existence results for the 1-harmonic flow from a domain of R m into the first hyper-octant of the N -dimensional unit sphere, under homogeneous Neumann boundary conditions. The arguments rely on a notion of “geodesic representative” of a BV-vector field on its jump set.

Unit spheren-sphereGeodesicApplied MathematicsMathematical analysisA domainharmonic flowsOctant (solid geometry)non-convex variational problems1-harmonic flowlower semi-continuity and relaxation; total variation flow; 1-harmonic flow; non-convex variational problems; image processing; geodesic; partial differential equations; harmonic flowsimage processingHomogeneoustotal variation flowNeumann boundary conditionJumppartial differential equationslower semi-continuity and relaxationgeodesicMathematics
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THE 1-HARMONIC FLOW WITH VALUES IN A HYPEROCTANT OF THE N-SPHERE

2014

We prove the existence of solutions to the 1-harmonic flow — that is, the formal gradient flow of the total variation of a vector field with respect to the [math] -distance — from a domain of [math] into a hyperoctant of the [math] -dimensional unit sphere, [math] , under homogeneous Neumann boundary conditions. In particular, we characterize the lower-order term appearing in the Euler–Lagrange formulation in terms of the “geodesic representative” of a BV-director field on its jump set. Such characterization relies on a lower semicontinuity argument which leads to a nontrivial and nonconvex minimization problem: to find a shortest path between two points on [math] with respect to a metric w…

Unit spherenonconvex variational problemsriemannian manifolds with boundaryGeodesicn-sphereharmonic flows68U1053C2253C4435K9235K67Neumann boundary conditionpartial differential equations49J45MathematicsNumerical Analysisnonlinear parabolic systems; lower semicontinuity and relaxation; total variation flow; 1-harmonic flow; image processing; harmonic flows; partial differential equations; image processing.; geodesics; riemannian manifolds with boundary; nonconvex variational problemslower semicontinuity and relaxation58E20Applied MathematicsMathematical analysis49Q201-harmonic flowimage processingFlow (mathematics)35K55Metric (mathematics)total variation flowVector fieldnonlinear parabolic systemsBalanced flowAnalysisgeodesics
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Study of USH1 Splicing Variants through Minigenes and Transcript Analysis from Nasal Epithelial Cells

2012

Usher syndrome type I (USH1) is an autosomal recessive disorder characterized by congenital profound deafness, vestibular areflexia and prepubertal retinitis pigmentosa. The first purpose of this study was to determine the pathologic nature of eighteen USH1 putative splicing variants found in our series and their effect in the splicing process by minigene assays. These variants were selected according to bioinformatic analysis. The second aim was to analyze the USH1 transcripts, obtained from nasal epithelial cells samples of our patients, in order to corroborate the observed effect of mutations by minigenes in patient’s tissues. The last objective was to evaluate the nasal ciliary beat fre…

Usher syndromelcsh:Medicinemedicine.disease_causeGene SplicingMolecular cell biologyAutosomal Recessivelcsh:ScienceGeneticsMutationMultidisciplinaryCadherinsMyosin VIIaRNA splicingSensory PerceptionUsher SyndromesResearch ArticleRNA SplicingCadherin Related ProteinsBiologyMyosinsNoseGenetic MutationRetinitis pigmentosamedicineGeneticsotorhinolaryngologic diseasesHumansCiliaBiologyMessenger RNAlcsh:RIntronMutation TypesComputational BiologyGenetic VariationEpithelial CellsHuman Geneticsmedicine.diseaseMolecular biologyRNA processingMutagenesisCase-Control StudiesMutationGenetics of Diseaselcsh:QGene expressionSensory DeprivationPCDH15MinigeneCloningNeuroscience
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