Search results for " Virtual"

showing 10 items of 493 documents

Repurposing old drugs to fight multidrug resistant cancers.

2020

Overcoming multidrug resistance represents a major challenge for cancer treatment. In the search for new chemotherapeutics to treat malignant diseases, drug repurposing gained a tremendous interest during the past years. Repositioning candidates have often emerged through several stages of clinical drug development, and may even be marketed, thus attracting the attention and interest of pharmaceutical companies as well as regulatory agencies. Typically, drug repositioning has been serendipitous, using undesired side effects of small molecule drugs to exploit new disease indications. As bioinformatics gain increasing popularity as an integral component of drug discovery, more rational approa…

0301 basic medicineVirtual screeningCancer ResearchDrug repurposingSettore BIO/11 - Biologia MolecolareAntineoplastic AgentsDrug resistanceBioinformatics03 medical and health sciencesClinical cancer trials; Drug repurposing; Multidrug resistant cancer; Pharmacophore modelling; Virtual screening0302 clinical medicineNeoplasmsDrug DiscoveryMedicineHumansPharmacology (medical)Computer SimulationRepurposingPharmacologyVirtual screeningDrug discoverybusiness.industryDrug RepositioningComputational BiologyDrug Resistance Multiple3. Good healthMultiple drug resistanceDrug repositioning030104 developmental biologyInfectious DiseasesOncologyDrug developmentDrug Resistance Neoplasm030220 oncology & carcinogenesisMultidrug resistant cancerPharmacophore modellingPharmacophorebusinessClinical cancer trialsDrug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
researchProduct

An Industrial Automation Course: Common Infrastructure for Physical, Virtual and Remote Laboratories for PLC Programming

2018

<span style="font-family: 'Times New Roman',serif; font-size: 10pt; mso-fareast-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: DE; mso-bidi-language: AR-SA;">This work describes the development of a teaching strategy to leverage current simulation tools and promote learning of industrial automation systems. Specifically, Programmable Logic Controller (PLC) programming in an industrial automation course. We propose an infrastructure where it is possible to work with physical, virtual and mixed laboratories</span>

0301 basic medicinelcsh:T58.5-58.64Computer sciencebusiness.industrylcsh:Tlcsh:Information technologyIndustrial Automation Teaching On-line Education OPC-UA Virtual Laborato-ry Virtual commissioning PLC programmingGeneral EngineeringProgrammable logic controllerAutomationlcsh:TechnologyEnsenyament virtual03 medical and health sciences030104 developmental biologyTheoryofComputation_MATHEMATICALLOGICANDFORMALLANGUAGESLeverage (statistics)businessSoftware engineeringIndustrial automation systemsAutomatitzacióInternational Journal of Online Engineering (iJOE)
researchProduct

A computational approach for the assessment of executive functions in patients with obsessive-compulsive disorder

2019

Previous studies on obsessive–compulsive disorder (OCD) showed impairments in executive domains, particularly in cognitive inhibition. In this perspective, the use of virtual reality showed huge potential in the assessment of executive functions; however, unfortunately, to date, no study on the assessment of these patients took advantage of the use of virtual environments. One of the main problems faced within assessment protocols is the use of a limited number of variables and tools when tailoring a personalized program. The main aim of this study was to provide a heuristic decision tree for the future development of tailored assessment protocols. To this purpose, we conducted a study that…

050103 clinical psychologyDecision treeObsessive–compulsive disordersObsessive-compulsive disordersVirtual realityObsessive–compulsive disorderArticleVirtual realityExecutive functions03 medical and health sciences0302 clinical medicineCognitive assessmentSettore M-PSI/08 - Psicologia ClinicaSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.Decision treeMedicineComputational models0501 psychology and cognitive sciencesSettore MED/25 - PsichiatriaProtocol (science)Computational modelbusiness.industry05 social sciencesNeuropsychologySettore M-PSI/03 - PsicometriaCognitive assessment; Computational models; Cross-validation; Decision tree; Executive functions; Multiple errands test; Obsessive-compulsive disorders; Virtual realityCross-validationGeneral MedicineExecutive functionsTest (assessment)computational modelCognitive inhibitionexecutive functionMultiple errands testObsessive–compulsive disorders; virtual reality; multiple errands test; cognitive assessment; executive functions; computational models; decision tree; cross-validationbusiness030217 neurology & neurosurgeryCognitive psychology
researchProduct

Towards Digital Twinning on the Web: Heterogeneous 3D Data Fusion Based on Open-Source Structure

2023

Recent advances in Computer Science and the spread of internet connection have allowed specialists to virtualize complex environments on the web and offer further information with realistic exploration experiences. At the same time, the fruition of complex geospatial datasets (point clouds, Building Information Modelling (BIM) models, 2D and 3D models) on the web is still a challenge, because usually it involves the usage of different proprietary software solutions, and the input data need further simplification for computational effort reduction. Moreover, integrating geospatial datasets acquired in different ways with various sensors remains a challenge. An interesting question, in that r…

3D modelling digital twins virtual reality WebGIS WebGLGeneral Earth and Planetary Sciencesdigital twins;3D modelling; WebGL; virtual realitySettore ICAR/06 - Topografia E Cartografia
researchProduct

In assenza di intervento. Rappresentazioni digitali di restauri virtuali

2015

La simulazione della realtà attraverso le tecniche di rappresentazione digitale viene oggi in aiuto dei restauratori poiché consente loro di verificare l’impatto di un restauro ancor prima di intervenire. Ciò può contribuire a evitare interventi troppo invasivi e a contenere errate pratiche che, a volte, irrimediabilmente cancellano le tracce originali. Il saggio analizza alcune esperienze di ricerca sull’illuminazione nei modelli virtuali che sono emblematiche di un approccio possibile. Le ricostruzioni tridimensionali digitali analizzate forniscono non solo le informazioni spaziali e dimensionali ma anche gli aspetti cromatici e le caratteristiche di illuminazione di un’architettura. Lo s…

3D models virtual reconstruction virtual restoration illuminating the pastSettore ICAR/17 - DisegnoModelli 3D ricostruzione virtuale restauro virtuale illuminare il passato
researchProduct

Bim and architectural heritage: Towards an operational methodology for the knowledge and the management of cultural heritage

2016

The study aims to answer the growing need for virtuously organize informational apparatuses related to Cultural Heritage. We propose a methodology that integrates multidisciplinary processes of interaction with information aimed at survey, documentation, management, knowledge and enhancement of historic artifacts. It is needed to review and update the procedure of instrumental data acquisition, standardization and structuring of the acquired data in a three-dimensional semantic model as well as the subsequent representability and accessibility of the model and the related database. If the use of Building Information Modeling has in recent years seen a consolidation in the procedures and the…

3d modeling Big data Cultural heritage HbimVirtual heritageArchitectureArchitectural drawing and designSettore ICAR/17 - Disegnocultural heritage virtual heritage big data hbim 3d modelingNA1-9428NA2695-2793
researchProduct

Viajes de cine. El relato del turismo en el cine hispánico

2017

Entre las estrategias desarrolladas por la industria turística para captar la atención del público viajero hacia destinos concretos una de las más rentables consiste en convertirlos en escenarios de las tramas fílmicas. Como envoltorio de los relatos cinematográficos, dichos escenarios quedan grabados en el imaginario colectivo, que los transforma en objetos de deseo susceptibles de ser visitados más tarde o más temprano. El análisis de esa exhibición cinematográfica de los espacios autóctonos es el objeto de los trabajos contenidos en el libro. Mediante el estudio de películas concretas, los autores abordan asimismo otros aspectos que muestran cómo el cine hispánico se hace eco de las tran…

:CIENCIAS DE LAS ARTES Y LAS LETRAS::Otras especialidades artísticas [UNESCO]viaje virtualimaginarioturismocine hispánicodestino turísticoUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRAS::Otras especialidades artísticas
researchProduct

El fomento de la mediación y de otros medios alternativos de justicia (también) en relación con la sustracción internacional de menores en Europa

2021

El decidido fomento de la mediación y de otros instrumentos MASC en el ámbito del Derecho de familia internacional constituye una constante, en los últimos tiempos, en el panorama comparado internacional. También en relación con aquellas disputas que involucran a menores. La UE no es ajena a este proceso y contribuye decididamente a éste. Aunque persisten dudas sobre la virtualidad real de estos mecanismos en la práctica diaria internacional.

:CIENCIAS JURÍDICAS [UNESCO]ADRHague Conference on Private International LawMediationEuropean Union 482 525en los últimos tiemposUNESCO::CIENCIAS JURÍDICAS2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055229 El fomento de la mediación y de otros medios alternativos de justicia (también) en relación con la sustracción internacional de menores en Europa Esplugues MotaCarlos El decidido fomento de la mediación y de otros instrumentos MASC en el ámbito del Derecho de familia internacional constituye una constanteen el panorama comparado internacional. También en relación con aquellas disputas que involucran a menores. La UE no es ajena a este proceso y contribuye decididamente a éste. Aunque persisten dudas sobre la virtualidad real de estos mecanismos en la práctica diaria internacional. Mediationinternational legal kidnappingCouncil of EuropeEuropean UnionMASC
researchProduct

Herramientas virtuales para la comunicación directa entre los agentes de la comunidad educativa. Análisis de caso de la aplicación móvil Smart Schools

2017

La comunicacion directa entre los diferentes agentes de la comunidad educativa cada vez es mas factible por el uso de herramientas virtuales. En el presente articulo, analizamos el uso de la aplicacion movil Smart Schools para la comunicacion escuela- familia y gestion interna de un centro escolar. Como estudio de caso, seleccionamos uno de los primeros cinco centros pioneros donde se ha implantado, el CEIP Bachiller Alonso Lopez, de la Comunidad de Madrid.  Como metodologia de analisis, se han realizado encuestas y entrevistas en profundidad a una muestra representativa de cada uno de los perfiles (docentes, padres y equipo gestor) que estan utilizando dicha app . El objetivo es detectar c…

:CIENCIAS TECNOLÓGICAS [UNESCO]gestión académicaaplicación móvilComunicación virtualUNESCO::CIENCIAS TECNOLÓGICAScomunidad educativaSmart Schoolslcsh:Llcsh:L7-991lcsh:Education (General)lcsh:Education
researchProduct

MIME: A mixed-space collaborative system with three immersion levels and multiple users

2018

Shared spaces for remote collaboration are nowadays possible by considering a variety of users, devices, immersion systems, interaction capabilities, navigation paradigms, etc. There is a substantial amount of research done in this line, proposing different solutions. However, still a more general solution that considers the heterogeneity of the involved actors/items is lacking. In this paper, we present MIME, a mixed-space tri-collaborative system. Differently from other mixed-space systems, MIME considers three different types of users (in different locations) according to the level of immersion in the system, who can interact simultaneously – what we call a tri-collaboration. For the thr…

:CIENCIAS TECNOLÓGICAS [UNESCO]realidad aumentadaUNESCO::CIENCIAS TECNOLÓGICASrealidad virtual
researchProduct