Search results for " Western"

Is Green Harvesting a Useful Instrument to solve Market Problems in the Wine Sector? Some Lessons from Sicily

2016

The green harvesting (GH) policy measure has been introduced in Italy starting from the 2009/2010 wine season, with the goal of preventing market crises by reducing the yield of a given parcel to zero. In the 2010-2012 period, almost 85% of the national expenditure and about 81% of European Union (EU) expenditure for this measure have been showered on Sicily. This paper, after examining the application of GH in this Region, explores the motivations of 300 vine growers of Western Sicily for taking part, or refusing to do so, in the GH measure. The survey shows the contrasting nature of the opinions that the implementation of GH has caused among the interviewed sample. In fact, on the one han…

A Review on "Lyricism and Chinese Modern Poetics" by Zhang Songjian

2015

La recensione mette in luce il nodo focale della ricerca dello studioso cinese Zhang Songjian nella sua analisi sul Modernismo nella poesia cinese degli anni '40. Lo studioso innova l'ambito della ricerca introducendo i concetti di "lyricism", "anti-lyricism" e "deep lyricism" che contribuiscono ad aprire nuove prospettive nel dialogo critico Occidente-Oriente sulla poesia cinese. The review underlines the focus of the research of the Chinese scholar Zhang Songjian in his analysis of Chinese poetry Modernism of the 40s. His innovative research is based on the concepts of "lyricism", "anti-lyricism" and "deep-lyricism" that contribute the opening of new perspectives in the Western-Eastern di…

In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent.

2015

International audience; Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy derived from plasmacytoid dendritic cells. There is currently no accepted standard of care for treating this neoplasm, and therapeutic strategies have never been prospectively evaluated. Since blastic plasmacytoid dendritic cell neoplasm cells express high levels of interleukin-3 receptor α chain (IL3-Rα or CD123), antitumor effects of the interleukin-3 receptor-targeted drug SL-401 against blastic plasmacytoid dendritic cell neoplasm were evaluated in vitro and in vivo. The cytotoxicity of SL-401 was assessed in patient-derived blastic plasmacytoid dendritic cell neoplasm cell lines (CAL-1 and …

Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts

2014

International audience; Background: Inborn enzyme defects of mitochondrial fatty acid beta-oxidation (FAO) form a large group of genetic disorders associated to variable clinical presentations ranging from life-threatening pediatric manifestations up to milder late onset phenotypes, including myopathy. Very few candidate drugs have been identified in this group of disorders. Resveratrol (RSV) is a natural polyphenol with anti-oxidant and anti-inflammatory effects, recently shown to have beneficial metabolic properties in mice models. Our study explores its possible effects on FAO and mitochondrial energy metabolism in human cells, which are still very little documented.Methods: Using cells …

Regulation of the alpha-secretase ADAM10 by its prodomain and proprotein convertases.

2001

SPECIFIC AIMSTo identify the proprotein convertases responsible for maturation of the α-secretase ADAM10, we investigated the influence of PC7 and furin on ADAM10 processing and the resulting effect on amyloid precursor protein cleavage. We also examined the functional role of the ADAM10 prodomain by coexpression of a prodomain-deleted ADAM10 mutant together with its prodomain in trans.PRINCIPAL FINDINGS1. ADAM10 is proteolytically processed by PC7 and furinThe disintegrin metalloproteinase ADAM10 possesses α-secretase activity as well as a potential proprotein convertase recognition sequence (RKKR) after its prodomain. By amino-terminal sequencing of ADAM10 purified from bovine kidney plas…

Sea Urchin Mitochondrial Matrix Contains a 56-kDa Chaperonine-like Protein

1997

Abstract Paracentrotus lividus mitochondrial matrix contains a constitutive hsp of 56-KDa which cross reacts with a serum anti-hsp-60 chaperonine from yeast mitochondria. The localization of hsps preexisting or newly synthesized in different subcellular fractions of gastrula embryos is also analyzed by two-dimensional electrophoresis.

Immunological detection of phenylalanine hydroxylase protein in Drosophila melanogaster.

1992

A monoclonal antibody raised against monkey liver phenylalanine hydroxylase (PAH) has been used to detect this protein in Drosophila melanogaster. A cross-reacting material (CRM) band of apparent molecular mass 50-52 kDa, equivalent to that deduced for the Drosophila melanogaster PAH protein based on the pah gene cDNA sequence, has been detected. This CRM was analysed throughout development and showed an equivalent pattern to that reported for PAH activity in this insect, with maxima at pupariation and at pharate adult formation. Distribution of this CRM in larval tissues, the haemolymph and the adult body is mainly restricted to the larval fat body and the adult head. Demonstration of this…

IL SUCCIACAPRE CAPRIMULGUS EUROPAEUS (Aves Caprimulgiformes) NIDIFICANTE ALLO STAGNONE DI MARSALA (TRAPANI)

2017

First breeding of Nightjar Caprimulgus europaeus (Aves Caprimulgiformes) in the Stagnone di Marsala (Trapani, western Sicily)

Cataract surgery in West Africa: is couching still a choice?

2012

MiR-221 promotes stemness of breast cancer cells by targeting DNMT3b

2016

// Giuseppina Roscigno 1, 2 , Cristina Quintavalle 1, 2 , Elvira Donnarumma 3 , Ilaria Puoti 1 , Angel Diaz-Lagares 4 , Margherita Iaboni 1 , Danilo Fiore 1 , Valentina Russo 1 , Matilde Todaro 5 , Giulia Romano 6 , Renato Thomas 7 , Giuseppina Cortino 7 , Miriam Gaggianesi 5 , Manel Esteller 4 , Carlo M. Croce 6 , Gerolama Condorelli 1, 2 1 Department of Molecular Medicine and Medical Biotechnology, “Federico II” University of Naples, Naples, Italy 2 IEOS-CNR, Naples, Italy 3 IRCCS-SDN, Naples, Italy 4 Epigenetic and Cancer Biology Program (PEBC) IDIBELL, Hospital Duran I Reynals, Barcelona, Spain 5 Department of Surgical and Oncological Sciences, Cellular and Molecular Pathophysiology Lab…