Search results for " activity"

showing 10 items of 4540 documents

Calprotectin and spondyloarthritis

2017

medicine.medical_specialtyImmunologyGastroenterologyDisease activity03 medical and health sciences0302 clinical medicineInternal medicineAnimalsHumansImmunology and AllergyMedicineSpondylitis AnkylosingInflammation030203 arthritis & rheumatologyTumor Necrosis Factor-alphabusiness.industryPrognosisInfliximabGene Expression RegulationDisease Progression030211 gastroenterology & hepatologyImmunotherapyCalprotectinbusinessLeukocyte L1 Antigen ComplexBiomarkersExpert Review of Clinical Immunology
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Trajectories of Physical Activity Predict the Onset of Depressive Symptoms but Not Their Progression: A Prospective Cohort Study

2016

This prospective, community-based study examined trajectories of physical activity from childhood to adulthood and whether these trajectories contributed to depressive symptoms in adulthood to a greater degree than adulthood physical activity. Participants (n=3596) were from the ongoing Cardiovascular Risk in Young Finns Study which started in 1980. Depressive symptoms were measured with Beck Depression Inventory (BDI-II) in 2012, and physical activity was assessed from 1980 to 2011 with self-reports. Analyses were adjusted for age, sex, childhood negative emotionality, socioeconomic factors, previous depressive symptoms, social support, body mass index, and smoking status (1980–2007). High…

medicine.medical_specialtyLiikuntatiede - Sport and fitness sciencesArticle Subject515 PsychologyeducationPhysical activityphysical activity03 medical and health sciencesSocial support0302 clinical medicinedepressive symptomscohort studyMedicine030212 general & internal medicinelcsh:Sports medicineProspective cohort studyPsychiatryta315Socioeconomic statuskohorttitutkimusDepressive symptomsta5152. Zero hungerBiolääketieteet – Biomedicinebusiness.industryBeck Depression Inventoryta3124030227 psychiatrydepressionSmoking statusbusinesslcsh:RC1200-1245Body mass indexResearch ArticleJournal of Sports Medicine
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Differences in sedentary time and physical activity among mothers and children using a movement-to-music video program in the home environment: a pil…

2016

Measured objectively, less than a quarter of adults and under half of preschool children in Finland meet the physical activity recommendations. Moreover, higher sedentary time among parents (such as watching television) is associated with higher sedentary time of their children. The study introduces an intervention based on reducing sedentary behavior among mothers and their children. It utilizes a combination of music and exercise via a motivation-targeting movement-to-music video program in the home environment. Data were collected in summer 2014 from Finland’s Pirkanmaa region. Each mother–child pair (n = 24, child age: 4–7 years) was assigned to the intervention and control group. Both …

medicine.medical_specialtyLiikuntatiede - Sport and fitness sciencesChild ageKansanterveystiede ympäristö ja työterveys - Public health care science environmental and occupational healthPhysical activityphysical activityIntervention groupSittingvideoHome environment03 medical and health sciences0302 clinical medicineIntervention (counseling)sedentary behaviormedicineMovement to music030212 general & internal medicineSedentary timeMultidisciplinaryHome environmentPhysical activitybusiness.industryResearchmovement to musicVideo030229 sport sciencesSedentary behaviorhome environmentNaisten- ja lastentaudit - Gynaecology and paediatricsAccelerometerSedentary behavioraccelerometerPhysical therapybusiness
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Effects of 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cell growth, cell volume and nucleus size of mouse lymphoma cells.

1992

The effects of three 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cultured mouse lymphoma cells were studied and compared with those of N-methyl-bis-(2-chloroethyl)amine hydrochloride (Lost). The derivatives exert only little influence on cell proliferation and cell volume. However, all derivatives cause a concentration-dependent nucleus contraction, probably due to DNA cross-linkings. Bromodesoxyuridine modulates the effects of the derivatives on the DNA, leading to swelling of the nucleus, which may be caused by DNA strand-breaks. It is suggested that the derivatives exert synergistic effects with other factors. It is concluded that these studies are suitable for the prescreening …

medicine.medical_specialtyLymphomaHydrochlorideDNA damageBiologychemistry.chemical_compoundMiceInternal medicineDrug DiscoverymedicineTumor Cells CulturedAnimalsPharmacology (medical)PharmacologyCell NucleusCell growthBiological activityGeneral Medicinemedicine.diseaseMolecular biologyIn vitroLymphomaInfectious Diseasesmedicine.anatomical_structureEndocrinologyOncologychemistryFluorouracilNucleusDNACell DivisionChemotherapy
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Criterion validity of two physical activity and one sedentary time questionnaire against accelerometry in a large cohort of adults and older adults

2020

ObjectivesWe compared the ability of physical activity and sitting time questionnaires (PAQ) for ranking individuals versus continuous volume calculations (physical activity level (PAL), metabolic equivalents of task (MET), sitting hours) against accelerometry measured physical activity as our criterion.MethodsParticipants in a cohort from the Tromsø Study completed three questionnaires; (1) The Saltin-Grimby Physical Activity Level Scale (SGPALS) (n=4040); (2) The Physical Activity Frequency, Intensity and Duration (PAFID) questionnaire (n=5902)) calculated as MET-hours·week-1 and (3) The International Physical Activity questionnaire (IPAQ) short-form sitting question (n=4896). We validate…

medicine.medical_specialtyMedicine (General)medicinePhysical activityphysical activityPhysical Therapy Sports Therapy and RehabilitationSittingMetabolic equivalent03 medical and health sciencessitting time0302 clinical medicineR5-920Criterion validityMedicineOrthopedics and Sports Medicine030212 general & internal medicine1506Sedentary timebusiness.industryOriginal research030229 sport sciencesVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Physical activity levelaccelerometerQuartileCohortPhysical therapyepidemiologyVDP::Medical disciplines: 700::Sports medicine: 850business
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Efficacia di Buprenorfina/Naloxone nel trattamento delle tossicodipendenze: monitoraggio dei pazienti in terapia presso il Ser.T. di Marsala, ASL n. …

2018

Il lavoro sperimentale è stato eseguito nel periodo gennaio 2016-marzo 2017, presso il Ser.T. di Marsala dell’ASL n. 9 di Trapani, sotto la guida del Dott. Gaetano Gurgone e del Prof. Fabio Venturella, lavoro in cui sono stati altresì analizzati i dati relativi agli ultimi cinque anni. Il compito prevalente del Ser.T. è l’assessment, inteso come processo di raccolta, integrazione ed interpretazione delle informazioni.Si esplica attraverso: la diagnosi, la cura, la riabilitazione. Questo lavoro vuole essere quindi il resoconto di 15 mesi di osservazione su pazienti trattati con Buprenorfina/Naloxone,operando un confronto con pazienti trattati con il Metadone.Il campione è costituito da 32 so…

medicine.medical_specialtyMethadone hydrochloridebusiness.industryCravingMental activityWorld healthHeroinBuprenorfina Metadone NaloxoneNaloxonemental disordersSettore BIO/14 - FarmacologiaMedicinemedicine.symptombusinessPsychiatrymedicine.drug
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TREATMENT WITH SILDENAFIL PREVENTS IMPAIRMENT OF LEARNING IN RATS BORN TO PRE-ECLAMPTIC MOTHERS

2010

Pre-eclampsia is an important hypertensive pregnancy disorder and a main cause of maternal and fetal morbidity and mortality Children born from mothers with preeclampsia may present cognitive deficits The mechanisms leading to this cognitive impairment remain unclear and no treatments to improve it have been tested Pre-eclampsia is associated with impaired regulation of the nitric oxide 3 5 guanosine monophosphate cyclic (cGMP) pathway, which modulates some cognitive functions We hypothesized that alterations in the NO-cGMP pathway would be involved in the mechanisms leading to cognitive impairment in rats born to pre-eclamptic mothers and that treatment with sildenafil an inhibitor of the …

medicine.medical_specialtyMicrodialysisSildenafilPhosphodiesterase InhibitorsMicrodialysisGlutamic AcidBlood PressureMotor ActivityNitric OxidePiperazinesSildenafil CitrateNitric oxideDiscrimination Learningchemistry.chemical_compoundPre-EclampsiaIn vivoPregnancynitric oxideInternal medicineCerebellummedicineAnimalsLearningSulfonesMaze LearningCyclic GMPFetusbiologyGeneral NeurosciencePhosphodiesteraseCognitionpre eclampsiaRatsNitric oxide synthaseEndocrinologyNG-Nitroarginine Methyl EsterchemistryPurinesPrenatal Exposure Delayed Effectsbiology.proteinFemale3-5 guanosine monophosphate cyclic (cGMP)Nitric Oxide SynthasePsychologycognitive function sildenafil
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Chronical haloperidol and clozapine treatment in rats: Differential RNA display analysis, behavioral studies and serum level determination

1998

1. Adult, female rats were treated orally for 23 days with 1.6 mg/kg haloperidol or 36 mg/kg clozapine per day, to study chronic effects of the two neuroleptics. 2. At five time points during the neuroleptic treatment, animal behavior was recorded in an open field and locomotive activity was analysed. At the end of the experiment, rats were decapitated, blood samples were collected and serum concentrations of haloperidol and clozapine were determined by a radioreceptor or HPLC assay, respectively. RNA was isolated from each brain, without cerebellum, and subjected to differential RNA display. 3. Mean serum concentrations were 8 ng/ml for haloperidol and 21 ng/ml for clozapine. Analysis of o…

medicine.medical_specialtyMotor ActivityPharmacologyPolymerase Chain ReactionOpen fieldRats Sprague-DawleyPharmacokineticsOral administrationInternal medicineGene expressionmedicineHaloperidolAnimalsRNA MessengerClozapineBiological PsychiatryClozapineDNA PrimersPharmacologybusiness.industryAntagonistBrainRNARatsEndocrinologyHaloperidolFemalebusinessAntipsychotic Agentsmedicine.drugProgress in Neuro-Psychopharmacology and Biological Psychiatry
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Evaluation of movement and brain activity

2021

Clinical neurophysiology studies can contribute important information about the physiology of human movement and the pathophysiology and diagnosis of different movement disorders. Some techniques can be accomplished in a routine clinical neurophysiology laboratory and others require some special equipment. This review, initiating a series of articles on this topic, focuses on the methods and techniques. The methods reviewed include EMG, EEG, MEG, evoked potentials, coherence, accelerometry, coherence, posturography (balance), gait, and sleep studies. Functional MRI (fMRI) is also reviewed as a physiological method that can be used independently or together with other methods. A few applicat…

medicine.medical_specialtyMovement disordersBrain activity and meditationMovementNeuroimagingElectroencephalographyClinical neurophysiologyArticlePhysical medicine and rehabilitationGait (human)Physiology (medical)medicineHumansBalance (ability)Brain MappingMovement Disordersmedicine.diagnostic_testElectromyographyMovement (music)business.industryPosturographyBrainMagnetoencephalographyElectroencephalographyMagnetic Resonance ImagingSensory SystemsNeurologyNeurology (clinical)medicine.symptomGait AnalysisbusinessClinical Neurophysiology
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Effectiveness of technology-based distance physical rehabilitation interventions on physical activity and walking in multiple sclerosis: a systematic…

2016

Objective: To determine the effectiveness of technology-based distance physical rehabilitation interventions in multiple sclerosis (MS) on physical activity and walking. Data sources: A systematic literature search was conducted in seven databases from January 2000 to September 2016. Randomized controlled trials of technology-based distance physical rehabilitation interventions on physical activity and walking outcome measures were included. Methods: Methodological quality of the studies was determined and a meta-analysis was performed. In addition, a subanalysis of technologies and an additional analysis comparing to no treatment were conducted. Results: The meta-analysis consisted of 11 s…

medicine.medical_specialtyMultiple SclerosishyvinvointiteknologiaPsychological interventionPhysical activityphysical activitydistance physical rehabilitationWalkingMean differencelaw.inventionwalking03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationsystematic reviewRandomized controlled trialMS-tautilawmedicineHumans030212 general & internal medicineMethodological qualityExerciseRandomized Controlled Trials as TopicTelerehabilitationbusiness.industryMultiple sclerosisRehabilitationOutcome measuresmedicine.diseaserehabilitation technologyMeta-analysisPhysical therapykuntoutusbusinessfyysinen aktiivisuus030217 neurology & neurosurgeryDisability and Rehabilitation
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