Search results for " aged"

showing 10 items of 14784 documents

The lived experience of rescuing people who have driven into floodwater: Understanding challenges and identifying areas for providing support.

2018

Background: Drowning is a major public health issue, with risk increasing during times of flood. Driving into floodwater is a major risk factor for flood-related drowning and injury, and despite widespread public health campaigns, many people continue to undertake this risky behaviour and require rescue. Purpose: We aimed to identify key challenges faced by emergency services personnel when rescuing those who have driven into floodwater, and to identify strategies for supporting rescuers in this important role. Methods: Australian flood rescue operators (N = 8) who had previously rescued a driver who had driven into floodwater participated in semi-structured interviews. Data were analysed u…

pelastushenkilöstöAdultMaleinjuryPoison controlHealth PromotionSuicide preventionOccupational safety and healthInterviews as Topic03 medical and health sciencesYoung Adult0302 clinical medicinehukkuminenInjury preventionmedicineRescue WorkHumans030212 general & internal medicineCooperative Behavioremergency servicesCommunity and Home Care030505 public healthDrowningPublic Health Environmental and Occupational HealthAustraliaEmergency RespondersHuman factors and ergonomicsta3142tulvatfloodMiddle Agedworkplacesmedicine.diseaseFloodsonnettomuudetpelastustoimiHealth promotionBusinessMedical emergencyThematic analysis0305 other medical sciencequalitative methodsQualitative researchHealth promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals
researchProduct

Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis.

2003

Inflammation underlies both onset and perpetuation of atherosclerosis. Plasma lipoproteins transport the platelet-activating factor-acetylhydrolase (PAF-AH) with potentially anti-inflammatory activities. Our aim was to determine whether PAF-AH activity was associated with inflammatory markers and with coronary artery disease (CAD). PAF-AH activity and a panel of inflammatory mediators were measured in plasma of 496 patients with CAD and in 477 controls; 276 patients presented with stable angina pectoris and 220 with acute coronary syndrome (ACS). Individuals within the highest quartile of PAF-AH activity had an 1.8-fold increase in CAD risk [95% confidence interval (CI), 1.01 to 3.2; P = 0.…

platelet-activating factorAdultMaleRiskmedicine.medical_specialtyAcute coronary syndromePAF acetylhydrolaseStatinCross-sectional studymedicine.drug_classMutation MissenseInflammationAngiotensin-Converting Enzyme InhibitorsQD415-436Coronary Artery DiseaseBiochemistryCoronary artery diseaseEndocrinologySex FactorsRisk FactorsInternal medicinemedicineHumansAgedInflammationbusiness.industryCell BiologySyndromeMiddle Agedmedicine.diseaseConfidence intervalCross-Sectional StudiesQuartile1-Alkyl-2-acetylglycerophosphocholine EsteraseAcute DiseaseCardiologylipids (amino acids peptides and proteins)Femaleatherosclerosismedicine.symptombusinessJournal of lipid research
researchProduct

Ensuring the comparability of cross-national survey data on intimate partner violence against women: a cross-sectional, population-based study in the…

2020

Objectives To ensure the cross-national comparability of the set of questions addressing physical and sexual intimate partner violence against women (IPVAW) included in the European Union (EU) Agency for Fundamental Rights (FRA) survey. Once the measurement invariance of these measures is established, we aim to make appropriate and valid comparisons of the levels of physical and sexual IPVAW across the EU countries. Design Cross-sectional, population-based study. Participants Data were drawn from the survey conducted by the FRA on violence against women, including the responses of 42 002 adult women from the 28 countries of the EU. Main outcome measures The set of questions addressing lifet…

psychometricsAdultEvidence-based practiceInternationalityPsychometricsAdolescentintimate partner violencePopulationGlobal HealthYoung AdultEnvironmental healthCross-national researchPrevalencemedia_common.cataloged_instanceMedicineHumansMeasurement invariance1506European UnionEuropean unioneducationmedia_commonAgededucation.field_of_studybusiness.industryComparabilitypublic healthR1699Reproducibility of ResultsGeneral MedicineMiddle AgedPsicologíameasurement invarianceCross-Sectional Studiescross-national researchDomestic violenceMedicineFemalebusinessBMJ Open
researchProduct

Chronic pain affects the whole person--a phenomenological study.

2014

The aim of this qualitative study was to explore participants' perspectives on the effects of chronic pain on the psychophysical unity.Thirty-four chronic pain outpatients were interviewed, and the transcribed interviews were analysed with Giorgi's four-phase phenomenological method. The mean age of the participants was 48 years, and 19 of them were women. For 21 of the participants, the pain duration was more than 5 years, and most had degenerative spinal pain.The results of this whole research project indicated that the phenomenon chronic pain consisted of four essential themes: Pain affects the whole person, invisibility, negativity, and dominance of pain. This study concentrates only on…

psychosocialAdultMalemedicine.medical_specialtySensationInterviews as TopicQuality of lifeAdaptation PsychologicalmedicineHumansPsychiatryQualitative ResearchAgedHealth Services Needs and DemandLonelinessRehabilitationChronic painSocial SupportLonelinessMean ageta3141Middle Agedmedicine.diseaseDistressQuality of LifePain catastrophizingFemalemedicine.symptomChronic PainPsychologyPsychosocialQualitative researchDisability and rehabilitation
researchProduct

Kolmevuotiaiden päiväkotilasten mitattu fyysinen aktiivisuus

2012

Tämän tutkimuksen tarkoituksena oli selvittää kolmevuotiaiden lasten fyysisen aktiivisuuden määrä ja intensiteetti sekä selvittää täyttyvätkö alle kouluikäisten Varhaiskasvatuksen liikunnan suositukset (2005) kahden tunnin reippaasta päivittäisestä liikunnasta tutkimukseen osallistuvilla lapsilla. Tutkimuksessa vertailtiin myös poikien ja tyttöjen sekä arki- ja viikonlopun päivien välisiä eroja. Aineisto kerättiin 14 vapaaehtoisesta päiväkodista elokuusta lokakuuhun 2010. Lasten fyysinen aktiivisuus mitattiin ActiGraph GT3Xkiihtyvyysmittareilla viiden peräkkäisen päivän ajan. Hyväksyttävä aineisto, vähintään kahdeksan tuntia mittausta kolmena arkipäivänä ja yhtenä viikonlopun päivänä, saati…

päiväkoti-ikäiset lapsetaccelerometerpreschool aged childrenchildcare centrekotiphysical activitypäiväkotikiihtyvyysmittarifyysinen aktiivisuus
researchProduct

Medium-term effects of bisoprolol administration on renal hemodynamics and function in mild to moderate essential hypertension

2007

Arterial hypertension is a significant cause of end-stage renal failure; effective treatment of hypertensive patients reduces the rate of progression of this disorder. ss-Blockers, particularly nonselective agents, are associated with deterioration of renal function in patients with chronic renal failure. Previous studies on the interaction of the beta1-selective adrenergic antagonist bisoprolol with kidney function have been performed only acutely and over the short term. This study was designed to evaluate the antihypertensive efficacy and effects on renal hemodynamics and function of bisoprolol during medium-term (6 mo) treatment of patients with mild to moderate essential hypertension. …

renal hemodynamicsAdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaAdrenergic beta-AntagonistsHemodynamicsRenal functionBlood PressureKidney Function TestsPlaceboEssential hypertensionDrug Administration ScheduleRenal CirculationInternal medicineHeart ratemedicineAdrenergic antagonistBisoprololHumansPharmacology (medical)Antihypertensive Agentsbusiness.industryessential hypertensionGeneral MedicineMiddle Agedmedicine.diseaseBlood pressureBisoprololHypertensionCardiologyFemalebusinessmedicine.drugAdvances in Therapy
researchProduct

Microvascular periodontal alterations: A possible relationship between periodontitis and rheumatoid arthritis.

2007

Abstract BACKGROUND: Microvascular involvements represent one of the first steps in many autoimmune diseases such as rheumatoid arthritis (RA). The aim of this study was to investigate the differences in periodontal microcirculation between healthy subjects and patients suffering from RA. METHODS: Thirty healthy subjects and 30 patients suffering from RA were examined. The patients who showed conditions known to compromise microcirculation, such as diabetes, hypertension, pharmacological treatments, were not included in the group of healthy patients. All the patients were non-smokers. Periodontal capillaroscopy was used to investigate the characteristics of microcirculation. Visibility, cou…

rheumatoid arthritisAdultMalePeriodontiumMicrocirculationMiddle AgedperiodontalCapillariesArthritis Rheumatoidperiodontal; rheumatoid arthritisCase-Control StudiesHumansFemalePeriodontitisAgedClinical hemorheology and microcirculation
researchProduct

Good clinical response, remission, and predictors of remission in rheumatoid arthritis patients treated with tumor necrosis factor-α blockers: The GI…

2007

OBJECTIVE: To assess the prevalence of good clinical response and remission in rheumatoid arthritis (RA) patients with longstanding disease treated with anti-tumor necrosis factor-alpha (TNF-alpha) drugs at outpatient clinics. METHODS: Retrospective national study of 14 academic tertiary referral rheumatology medical centers. RA patients with a Disease Activity Score (DAS28) > 3.2 were defined as having active disease and could start TNF-alpha blockers. All patients received one TNF-alpha blocker plus methotrexate (10-20 mg/wk). At the third month the patients were categorized as responders or nonresponders, based on improvement of at least 0.25 of the Health Assessment Questionnaire (HAQ).…

rheumatoid arthritisAdultMaleQuality Assurance Health Carepredictors of remissionTumor Necrosis Factor blockersAntibodies Monoclonal HumanizedSeverity of Illness IndexReceptors Tumor Necrosis FactorEtanerceptArthritis RheumatoidRheumatoid arthritis; Good clinical response; Tumor Necrosis Factor blockersPredictive Value of TestsHumansRheumatoid arthritispredictors of remission; rheumatoid arthritis; tumor necrosis factor-alpha blockersAgedRetrospective StudiesGood clinical responseTumor Necrosis Factor-alphatumor necrosis factor-alpha blockersRemission InductionAdalimumabAntibodies MonoclonalMiddle AgedPrognosisInfliximabLogistic ModelsMethotrexateTreatment Outcomedisability score; good clinical response; remission; rheumatoid arthritis; tumor necrosis factor-α blockersItalyAntirheumatic AgentsImmunoglobulin GFemale
researchProduct

Etanercept maintains the clinical benefit achieved by infliximab in patients with rheumatoid arthritis who discontinued infliximab because of side ef…

2007

Objective: To evaluate the efficacy of switching to etanercept treatment in patients with rheumatoid arthritis who already responded to infliximab, but presented side effects. Methods: Charts of 553 patients with rheumatoid arthritis were retrospectively reviewed to select patients who responded to the treatment with infliximab and switched to etanercept because of occurrence of adverse effects. Clinical data were gathered during 24 weeks of etanercept treatment and for the same period of infliximab treatment before infliximab was stopped. Disease Activity Score computed on 44 joints (DAS-44), erythrocyte sedimentation rate (ESR) 1st hour, Visual Analogue Scale (VAS) of pain, Health Assessm…

rheumatoid arthritisMaleConcise ReportArthritisGastroenterologyReceptors Tumor Necrosis FactorEtanerceptEtanerceptArthritis Rheumatoidimmune system diseasesImmunology and AllergyHealth Status Indicatorsskin and connective tissue diseasesmedicine.diagnostic_testbiologyAntibodies MonoclonalMiddle AgedC-Reactive ProteinTreatment OutcomeBiologic agents; etanercept; infliximab; infusion reactionRheumatoid arthritisErythrocyte sedimentation rateAntirheumatic AgentsFemalemedicine.drugmusculoskeletal diseasesAdultmedicine.medical_specialtyVisual analogue scaleImmunologyBlood Sedimentationinfusion reactionGeneral Biochemistry Genetics and Molecular BiologyRheumatologyInternal medicinemedicineHumansAdverse effectRetrospective StudiesChi-Square Distributionbusiness.industryTumor Necrosis Factor-alphaC-reactive proteinetanercept; infliximab; rheumatoid arthritismedicine.diseaseInfliximabInfliximabSurgeryBiologic agentsstomatognathic diseasesImmunoglobulin Gbiology.proteinbusinessinfliximabetanercept
researchProduct

Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study

2014

[Background] It is unknown whether individuals at high cardiovascular risk sustain a benefit in cardiovascular disease from increased olive oil consumption. The aim was to assess the association between total olive oil intake, its varieties (extra virgin and common olive oil) and the risk of cardiovascular disease and mortality in a Mediterranean population at high cardiovascular risk.

riesgoMediterranean diethumanosMyocardial InfarctionCardiovascularlaw.inventionCohort StudiesRandomized controlled triallawRisk FactorsNeoplasmsestudios prospectivosNutsMyocardial infarctionProspective StudiesProspective cohort studyestudios de cohortesmediana edadMedicine(all)neoplasiaseducation.field_of_studyancianodietaGeneral MedicineMiddle AgedStrokeOli d'olivaCardiovascular diseasesCardiovascular Diseasesaceites de plantasCohort studyRiskPREDIMEDmedicine.medical_specialtyPopulationenfermedades cardiovascularesNational Death IndexMediterranean dietEnvironmental healthmedicineMortalitatHumansPlant Oilsfactores de riesgoaccidente cerebrovascularMortalityeducationinfarto de miocardioAgedMediterranean DietProportional hazards modelbusiness.industryMalalties cardiovascularsmedicine.diseaseSurgeryDietnuecesbusinessOlive oil
researchProduct