Search results for " aging."

showing 10 items of 556 documents

Association between sarcopenia and quality of life among adults aged ≥ 65 years from low- and middle-income countries

2022

Background Sarcopenia has been associated with a lower quality of life (QoL). However, studies on this association from low- and middle-income countries (LMICs) are scarce. Aims To examine the association between sarcopenia and QoL, in a large nationally representative sample of older adults from six LMICs. Methods Cross-sectional, community-based data from the WHO study on global ageing and adult health (SAGE) were analysed. Non-severe sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength but no slow gait speed, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. QoL was assessed with the 8-item WHO QoL in…

MaleSarcopeniaAgingCross-Sectional StudiesHand StrengthSmith L. Sánchez G. Veronese N. Soysal P. Kostev K. Jacob L. Oh H. Tully M. Butler L. Parsa A. et al. -Association between sarcopenia and quality of life among adults aged ≥ 65 years from low- and middle-income countries.- Aging clinical and experimental research 2022Quality of LifeHumansLow- and middle-income countries Older adults Quality of life SarcopeniaFemaleGeriatrics and GerontologyDeveloping CountriesAgedAging Clinical and Experimental Research
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Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries

2022

Background: Sleep duration may influence risk for sarcopenia but studies on this topic are scarce, especially from low and- middle-income countries (LMICs). Thus, the aim of the present study was to investigate the association between sleep duration and sarcopenia among adults aged ≥ 65 years from five LMICs (China, Ghana, India, Russia, South Africa). Methods: Cross-sectional, community-based data from the WHO study on global ageing and adult health (SAGE) were analysed. Sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. Self-reported sleep duration i…

MaleSarcopeniaAgingCross-Sectional StudiesSleep problems · Sarcopenia · Low- and- middle income countries · Older adultsHand StrengthSmith L. Shin J. I. Veronese N. Soysal P. López Sánchez G. F. Pizzol D. Demurtas J. Tully M. A. Barnett Y. Butler L. et al. -Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries.- Aging clinical and experimental research 2022PrevalenceHumansFemaleGeriatrics and GerontologySleepDeveloping CountriesAging Clinical and Experimental Research
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Serum albumin and muscle measures in a cohort of healthy young and old participants

2015

Consensus on clinically valid diagnostic criteria for sarcopenia requires a systematical assessment of the association of its candidate measures of muscle mass, muscle strength, and physical performance on one side and muscle-related clinical parameters on the other side. In this study, we systematically assessed associations between serum albumin as a muscle-related parameter and muscle measures in 172 healthy young (aged 18–30 years) and 271 old participants (aged 69–81 year) from the European MYOAGE study. Muscle measures included relative muscle mass, i.e., total- and appendicular lean mass (ALM) percentage, absolute muscle mass, i.e., ALM/height2 and total lean mass in kilograms, handg…

MaleSarcopeniaAgingCross-sectional studySerum albuminAbsorptiometry PhotonReference Values80 and overMedicineMusclemassYoung adultAged 80 and overbiologyGeneral MedicinePhotonC-Reactive Proteinmedicine.anatomical_structureCohortBody Composition/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleAdultmedicine.medical_specialtySarcopenia/metabolismAdolescentBody Composition/physiologySerum albuminArticleSerum Albumin/metabolismYoung AdultSDG 3 - Good Health and Well-beingInternal medicineHumansAbsorptiometryLife StyleAgedMuscle strengthbusiness.industryC-Reactive Protein/metabolismSkeletal muscleMuscle massmedicine.diseaseAging/physiologyPreferred walking speedAgeingCross-Sectional StudiesEndocrinologylihasmassaMuscle mass; Muscle strength; Sarcopenia; Serum albumin; Absorptiometry Photon; Adolescent; Adult; Aged; Aged 80 and over; Aging; Body Composition; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Male; Muscle Strength; Reference Values; Sarcopenia; Serum Albumin; Young Adult; Life StyleSarcopeniaLean body massbiology.proteinMuscle Strength/physiologyGeriatrics and GerontologybusinesslihasvoimaAGE
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<p>Agreement of a Short Form of the Self-Administered Multidimensional Prognostic Index (SELFY-MPI-SF): A Useful Tool for the Self-Assessment o…

2020

Alberto Cella,1 Alberto Ferrari,2 Giuseppe Rengo,3 Vincenzo Solfrizzi,4 Nicola Veronese,5 Matteo Puntoni,6 Sabrina Zora,1 Alberto Pilotto,1,4 Filippo Fimognari7 On behalf of the SELFY-MPI SIGOT Investigators1Geriatric Unit, Department of Geriatric Care, Orthogeriatrics and Rehabilitation, EO Galliera Hospital, Genova, Italy; 2Geriatric Unit, Arcispedale S. Maria Nuova, AUSL Reggio Emilia, Reggio Emilia, Italy; 3Department of Translational Medical Sciences, Division of Geriatrics, Federico II University, Napoli, Italy; 4Department of Interdisciplinary Medicine, University of Bari, Bari, Italy; 5Primary Care Department, Azienda ULSS 3 Serenissima, Venice, Italy; 6Scientific Coordination Unit,…

MaleSelf-assessmentGerontologySelf-AssessmentIndex (economics)Activities of daily livingInterpersonal RelationReproducibility of ResultNutritional StatusSample (statistics)Comorbidity03 medical and health sciencesCognition0302 clinical medicineRisk Factorsself assessmentActivities of Daily LivingHumansMedicineInterpersonal Relations030212 general & internal medicineGeriatric AssessmentAgedOriginal ResearchAged 80 and overFrailtybusiness.industryRisk FactorSelfReproducibility of ResultsCognitionGeneral MedicineMiddle AgedPhysical Functional Performancecomprehensive geriatric assessmentmedicine.diseaseComorbiditymultidimensional prognostic indexNutritional StatuClinical Interventions in AgingPolypharmacyFemaleIndependent LivingGeriatrics and GerontologybusinessOlder peoplecomprehensive geriatric assessment multidimensional prognostic index frailty self assessmen030217 neurology & neurosurgeryHumanClinical Interventions in Aging
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Clinical efficacy of blue light full body irradiation as treatment option for severe atopic dermatitis.

2011

Background Therapy of atopic dermatitis (AD) relies on immunosuppression and/or UV irradiation. Here, we assessed clinical efficacy and histopathological alterations induced by blue light-treatment of AD within an observational, non-interventional study. Methodology/Principal Findings 36 patients with severe, chronic AD resisting long term disease control with local corticosteroids were included. Treatment consisted of one cycle of 5 consecutive blue light-irradiations (28.9 J/cm2). Patients were instructed to ask for treatment upon disease exacerbation despite interval therapy with topical corticosteroids. The majority of patients noted first improvements after 2–3 cycles. The EASI score w…

MaleSkin PhysiologyAnatomy and PhysiologyLightmedicine.medical_treatmentlcsh:MedicinePediatric DermatologyAntigen Processing and RecognitionAtopic DermatitisDiseasePediatricsQuality of lifeYoung adultlcsh:ScienceSkinMultidisciplinarymedicine.diagnostic_testT CellsAllergy and HypersensitivityPhysicsElectromagnetic RadiationPhotodermatology and Skin AgingImmunosuppressionAtopic dermatitisMiddle Agedmedicine.anatomical_structureTreatment OutcomePatient SatisfactionObservational StudiesMedicineFemaleWhole-Body IrradiationResearch ArticleAdultmedicine.medical_specialtyLangerhans cellClinical Research DesignImmune CellsImmunologyColorDermatologyDermatitis AtopicYoung AdultUltraviolet RadiationBiopsymedicineHumansSerologic TestsBiologybusiness.industrylcsh:Rmedicine.diseaseDermatologyClinical trialImmune SystemChronic DiseaseQuality of Lifelcsh:QClinical ImmunologybusinessPloS one
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Sleep problems and subjective cognitive complaints among middle-aged and older adults in 45 low- and middle-income countries

2022

Background: Currently, a small body of evidence suggests that sleep problems are positively associated with subjective cognitive complaints (SCC). However, no studies on this topic exist from low- and middle-income countries (LMICs). Thus, we investigated the association between sleep problems and SCC in a large sample of middle-age and older adults from 45 LMICs. Methods: Cross-sectional, predominantly nationally representative, community-based data were analyzed from the World Health Survey. Sleep problems (such as difficulties falling asleep, waking up frequently during the night or waking up too early in the morning) in the last 30 days were self-reported. Two questions on subjective me…

MaleSleep Wake DisordersAgingSmith L. Oh H. Jacob L. López-Sánchez G. F. Veronese N. Soysal P. Shin J. I. Schuch F. Tully M. A. Butler L. et al. -Sleep problems and subjective cognitive complaints among middle-aged and older adults in 45 low- and middle-income countries.- Aging clinical and experimental research 2022Middle AgedSleep problems · Subjective cognitive complaints · Low- and middle-income countries · Older adultsCognitionCross-Sectional StudiesPrevalenceHumansFemaleGeriatrics and GerontologyDeveloping CountriesAged
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Association of neovascular age-related macular degeneration with month and season of birth in Italy

2016

In order to investigate the influence of season and month of birth on the risk of neovascular age-related macular degeneration (n-AMD) in Italy, we evaluated the month birth and sex of all patients, recorded in the anti-vascular endothelial growth factor (VEGF) monitoring registry of the Italian Medicines Agency, born between 1925-1944, who received intravitreal anti-VEGF injections for n-AMD between January 1, 2013 and July 29, 2015. The numbers of all births in Italy in the same years, extracted from the Italian National Institute of Statistics, were used to calculate the expected number of n-AMD cases. Overall, 45,845 patients (19,207 men, 26,638 women) received intravitreal anti-VEGF fo…

MaleVascular Endothelial Growth Factor AAginggenetic structuresMonth of birthVEGF receptorsneovascular AMDAngiogenesis InhibitorsAptamersMacular Degeneration0302 clinical medicineSeason of birthReceptors80 and overMedicineRegistriesAged 80 and overNeovascularization PathologicbiologyVascular Endothelial Growth FactorIncidenceIncidence (epidemiology)Aptamers NucleotideBevacizumabTreatment OutcomeItalyanti-VEGFFemaleSeasonsNucleotideNeovascular age-related macular degenerationResearch Papermedicine.drugAnti-VEGF; Month of birth; Neovascular age-related macular degeneration; Neovascular AMD; Season of birth; Aged; Aged 80 and over; Angiogenesis Inhibitors; Aptamers Nucleotide; Bevacizumab; Female; Humans; Incidence; Italy; Macular Degeneration; Male; Neovascularization Pathologic; Ranibizumab; Receptors Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Registries; Treatment Outcome; Vascular Endothelial Growth Factor A; Seasons; Aging; Cell BiologySeason of birthBevacizumabRecombinant Fusion ProteinsNeovascular AMDneovascular age-related macular degeneration03 medical and health sciencesRanibizumabAge relatedHumansNeovascularizationAgedPathologicseason of birthbusiness.industrymonth of birthAnti-VEGFCell BiologyMacular degenerationmedicine.diseaseeye diseasesanti-VEGF; month of birth; neovascular AMD; neovascular age-related macular degeneration; season of birthReceptors Vascular Endothelial Growth Factor030221 ophthalmology & optometrybiology.proteinsense organsRanibizumabbusinessMonth of birth030217 neurology & neurosurgeryDemographyAging
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2011–12 Seasonal Influenza Vaccines Effectiveness against Confirmed A(H3N2) Influenza Hospitalisation: Pooled Analysis from a European Network of Hos…

2013

BackgroundInfluenza vaccination strategies aim at protecting high-risk population from severe outcomes. Estimating the effectiveness of seasonal vaccines against influenza related hospitalisation is important to guide these strategies. Large sample size is needed to have precise estimate of influenza vaccine effectiveness (IVE) against severe outcomes. We assessed the feasibility of measuring seasonal IVE against hospitalisation with laboratory confirmed influenza through a network of 21 hospitals in the European Union.MethodsWe conducted a multicentre study in France (seven hospitals), Italy (one hospital), and Navarra (four hospitals) and Valencia (nine hospitals) regions in Spain. All ≥1…

MaleViral DiseasesEpidemiologyPilot ProjectsLogistic regressionmedicine.disease_cause0302 clinical medicineInfluenza A virusClinical Epidemiology030212 general & internal medicineEpidemiological Methodsmedia_commonAged 80 and overeducation.field_of_studyVaccinesMultidisciplinaryQVaccinationREpidemiology of AgingMiddle Aged3. Good healthVaccinationHospitalizationInfectious DiseasesInfluenza VaccinesMedicineFemaleSeasonsResearch ArticleAdultmedicine.medical_specialtyAdolescentInfluenza vaccineClinical Research DesignScience030231 tropical medicinePopulationMicrobiologyHistory 21st CenturyInfectious Disease Epidemiology03 medical and health sciencesYoung AdultInternal medicineVirologyVaccine DevelopmentInfluenza Humanmedicinemedia_common.cataloged_instanceHumansEuropean UnionEuropean unioneducationBiologyAgedbusiness.industryInfluenza A Virus H3N2 SubtypeCase-control studyImmunityViral VaccinesInfluenzaSample size determinationCase-Control StudiesImmunologyClinical ImmunologybusinessPLoS ONE
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Plantar flexor activation capacity and H reflex in older adults: adaptations to strength training.

2002

The purpose of this study was to investigate whether the voluntary neural drive and the excitability of the reflex arc could be modulated by training, even in old age. To this aim, the effects of a 16-wk strengthening program on plantar flexor voluntary activation (VA) and on the maximum Hoffman reflex (Hmax)-to-maximum M wave (Mmax) ratio were investigated in 14 elderly men (65–80 yr). After training, isometric maximum voluntary contraction (MVC) increased by 18% ( P < 0.05) and weight-lifting ability by 24% ( P < 0.001). Twitch contraction time decreased by 8% ( P < 0.01), but no changes in half relaxation time and in peak twitch torque were observed. The VA, assessed by twitch …

MaleVolitionAgingPhysiologydegenerationadaptationIsometric exerciseNerve conduction velocityhuman experimentH-ReflexTriceps surae muscleTwitch interpolationadaptation; aged; aging; article; controlled study; degeneration; excitability; exercise; Hoffmann reflex; human; human experiment; male; muscle contraction; muscle isometric contraction; muscle relaxation; muscle twitch; nerve conduction; normal human; plantaris muscle; priority journal; reflex arc; strength; torque; training; voluntary movement; Aging; Exercise; Triceps surae; Twitch interpolationAged 80 and overtrainingvoluntary movementReflex arcarticlereflex arcmusculoskeletal systemAdaptation Physiologicalmuscle twitchmedicine.anatomical_structuremuscle relaxationpriority journalCardiologyTriceps suraemedicine.symptomstrengthMuscle contractionMuscle Contractionmedicine.medical_specialtyWeight Liftingplantaris muscleStrength trainingPhysical exercisePhysical medicine and rehabilitationPhysiology (medical)Internal medicineexcitabilitymedicineHumanscontrolled studyhumannormal humanMuscle SkeletalExercisenerve conductionAgedmuscle isometric contractionbusiness.industrybody regionsHoffmann reflexTorqueH-reflexbusinessJournal of applied physiology (Bethesda, Md. : 1985)
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What physical performance measures predict incident cognitive decline among intact older adults? A 4.4 year follow up study

2016

Reductions in physical performance, cognitive impairment (CI) and decline (CD), are common in older age, but few prospective cohort studies have considered the relationship between these domains. In this study we investigated whether reduced physical performance and low handgrip/lower limbs strength, could predict a higher incidence of CI/CD during a 4-year follow-up among a cohort of elderly individuals. From 3099 older community-dwelling individuals initially enrolled in the Progetto Veneto Anziani (PRO.V.A.) study, 1249 participants without CI at the baseline were included (mean age 72.2 years, 59.5% females). Physical performance measures included the Short Physical Performance Battery …

Malecognitionmedicine.medical_specialtyAgingPoison controlWalkingNeuropsychological TestsBiochemistryNOPhysical performancePhysical performance Muscle strength Cognition03 medical and health sciences0302 clinical medicineCognitionEndocrinologyInjury preventionGeneticsMedicineHumansCognitive Dysfunction030212 general & internal medicineCognitive declineProspective cohort studyGeriatric AssessmentMolecular BiologyAgedAged 80 and overPsychiatric Status Rating ScalesHand Strengthbusiness.industryMuscle strengthIncidence (epidemiology)Confoundingphysical performanceCell BiologyPreferred walking speedLogistic ModelsItalyCohortPhysical therapyExercise Testmuscle strengthFemaleCognition; Muscle strength; Physical performance; Aging; Biochemistry; Cell Biology; Endocrinology; Genetics; Molecular Biologybusinesshuman activities030217 neurology & neurosurgeryFollow-Up Studies
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