Search results for " agricole"

Esercizio di attività agricole e statuto dell'imprenditore

2011

Efficacy of a 12-Week Simeprevir Plus Peginterferon/Ribavirin (PR) Regimen in Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype 4 (GT4) …

2017

Background HCV GT4 accounts for up to 20% of HCV infections worldwide. Simeprevir, given for 12 weeks as part of a 24- or 48-week combination regimen with PR is approved for the treatment of chronic HCV GT4 infection. Primary study objectives were assessment of efficacy and safety of simeprevir plus PR in treatment-naïve patients with HCV GT4 treated for 12 weeks. Primary efficacy outcome was sustained virologic response 12 weeks post-treatment (SVR12). Additional objectives included investigation of potential associations of rapid virologic response and baseline factors with SVR12. Methods This multicentre, open-label, single-arm study (NCT01846832) evaluated efficacy and safety of simepre…

Rapid differentiation between livestock-associated and livestock-independent Staphylococcus aureus CC398 clades.

2013

Staphylococcus aureus clonal complex 398 (CC398) isolates cluster into two distinct phylogenetic clades based on single-nucleotide polymorphisms (SNPs) revealing a basal human clade and a more derived livestock clade. The scn and tet(M) genes are strongly associated with the human and the livestock clade, respectively, due to loss and acquisition of mobile genetic elements. We present canonical single-nucleotide polymorphism (canSNP) assays that differentiate the two major host-associated S. aureus CC398 clades and a duplex PCR assay for detection of scn and tet (M). The canSNP assays correctly placed 88 S. aureus CC398 isolates from a reference collection into the human and livestock clade…

Strategie di Ri-produzione. Aziende agricole e strutture familiari nella Sicilia Centro-Occidentale

2011

Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes

2013

Neuroblastoma is an embryonic tumor arising from immature sympathetic nervous system cells. Recurrent genomic alterations include MYCN and ALK amplification as well as recurrent patterns of gains and losses of whole or large partial chromosome segments. A recent whole genome sequencing effort yielded no frequently recurring mutations in genes other than those affecting ALK. However, the study further stresses the importance of DNA copy number alterations in this disease, in particular for genes implicated in neuritogenesis. Here we provide additional evidence for the importance of focal DNA copy number gains and losses, which are predominantly observed in MYCN amplified tumors. A focal 5 kb…

D2R striatopallidal neurons inhibit both locomotor and drug reward processes.

2009

The specific functions of dopamine D(2) receptor-positive (D(2)R) striatopallidal neurons remain poorly understood. Using a genetic mouse model, we found that ablation of D(2)R neurons in the entire striatum induced hyperlocomotion, whereas ablation in the ventral striatum increased amphetamine conditioned place preference. Thus D(2)R striatopallidal neurons limit both locomotion and, unexpectedly, drug reinforcement.

Agricoltura e turismo a Ustica. Tipicità, tradizioni e patrimonio culturale

2020

Negli ultimi anni abbiamo assistito a un aumento graduale e progressivo di consapevolezza e di presa di coscienza rispetto all'importanza ed al valore dell'agricoltura, con un interesse sempre maggiore da parte di molteplici categorie di persone verso i prodotti di nicchia e le tipicità locali. In questo breve articolo, partendo dalla mia attuale esperienza di ricerca sul campo sull'isola di Pantelleria, vorrei tracciare degli spunti di riflessione sui concetti di “tipicità”, “tradizioni” e “patrimonio culturale”, nell'ottica di una possibile prospettiva di ricerca da intraprendere sul territorio di Ustica. Quando parliamo di patrimonio culturale, ci riferiamo a qualcosa di estremamente vas…

La concentration des terres dans le collimateur de l'Union européenne

2018

International audience; Par la voie d’une communication interprétative, la Commission européenne s’empare de la question de la maîtrise des terres agricoles au sein des pays de l’Union ; elle explicite les marges de manœuvres dont disposent les Etats membres pour réguler leurs marchés fonciers sans déborder du cadre juridique européen.

LA TRANSMISSION DE L'ENTREPRISE AGRICOLE EN SOCIÉTÉ

2017

National audience; La société, comme outil de transmission de l’entreprise agricole, suscite à la fois fascination et méfiance. En cette technique juridique reposent les espoirs de simplification et d’unification de la cession du patrimoine productif. Mais derrière le voile de la personnalité morale, se cache une réalité plus nuancée, tant les liens qui unissent les hommes à la terre ne sont pas toujours solubles dans la fiction sociétaire.

La transmission de l’exploitation agricole à l’épreuve des obligations environnementales 

2017

National audience; Longtemps tenues pour négligeables, les problématiques environnementales représentent dorénavant un aspect majeur de la transmission des exploitations agricoles. Que les obligations écologiques soient attachées aux biens formant l’outil de production ou à la personne de l’exploitant qui les a souscrites, leur sort interfère avec la cession de l’entreprise agricole.