Search results for " alcohol"

showing 10 items of 578 documents

Comparative Analysis of Machine Learning Methods to Predict Growth of F. sporotrichioides and Production of T-2 and HT-2 Toxins in Treatments with Et…

2021

The efficacy of ethylene-vinyl alcohol copolymer films (EVOH) incorporating the essential oil components cinnamaldehyde (CINHO), citral (CIT), isoeugenol (IEG), or linalool (LIN) to control growth rate (GR) and production of T-2 and HT-2 toxins by Fusarium sporotrichioides cultured on oat grains under different temperature (28, 20, and 15 °C) and water activity (aw) (0.99 and 0.96) regimes was assayed. GR in controls/treatments usually increased with increasing temperature, regardless of aw, but no significant differences concerning aw were found. Toxin production decreased with increasing temperature. The effectiveness of films to control fungal GR and toxin production was as follows: EVOH…

<i>Fusarium sporotrichioides</i>Water activityHealth Toxicology and MutagenesisToxins.MicrobiologiaHT-2 toxinToxicologyMachine learningcomputer.software_genreCitralfungal growthCinnamaldehydelaw.inventionchemistry.chemical_compoundBiofilms.LinaloolAprendizaje automático (Inteligencia artificial)lawpredictive microbiologyT-2 toxinMicroorganismes patògensPolímeros.Machine learning.ethylene-vinyl alcohol copolymersEssential oilEssences and essential oils.biologyPolymers.business.industryPetri dishRbiology.organism_classificationFusarium sporotrichioidesEsencias.IsoeugenolBiofilmes.essential oil pure componentsmachine learningchemistryMedicineArtificial intelligencebusinesscomputerToxinas y antitoxinas.Toxins
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Pattern of macrovascular invasion in hepatocellular carcinoma

2021

Background and aims: In patients with hepatocellular carcinoma (HCC), macrovascular invasion (MaVI) limits treatment options and decreases survival. Detailed data on the relationship between MaVI extension and patients' characteristics, and its impact on patients' outcome are limited. We evaluated the prevalence and extension of MaVI in a large cohort of consecutive HCC patients, analysing its association with liver disease and tumour characteristics, as well as with treatments performed and patients' survival. Methods: We analysed data of 4774 patients diagnosed with HCC recorded in the Italian Liver Cancer (ITA.LI.CA) database (2008-2018). Recursive partition analysis (RPA) was performed …

Ablation TechniquesMaleRegistrieCirrhosisClinical BiochemistryMesenteric Veinloco-regional treatment030204 cardiovascular system & hematologyBiochemistryGastroenterologysurgeryAntineoplastic AgentLiver disease0302 clinical medicineNon-alcoholic Fatty Liver Diseasecirrhosis; hepatocellular carcinoma; loco-regional treatment; portal vein thrombosis; surgery; transplantationAscitesAblation Techniqueportal vein thrombosisRegistries030212 general & internal medicineChronicSettore MED/12 - GastroenterologiaPortal VeinLiver DiseasesLiver NeoplasmsAsciteshepatocellular carcinomaGeneral MedicineMiddle AgedSorafenibPrognosisHepatitis BAlcoholicHepatitis CTumor BurdenSurvival RateItalyLiver NeoplasmHepatocellular carcinomaAsciteFemalemedicine.symptomLiver cancerHumanmedicine.medical_specialtyCarcinoma HepatocellularPrognosiAntineoplastic AgentsEnd Stage Liver Disease03 medical and health sciencesMesenteric VeinsHepatitis B ChronicInternal medicinemedicineHumansHepatectomyNeoplasm Invasivenessportal vein thrombosiLiver Diseases AlcoholicAgedNeoplasm Invasivene...Performance statusbusiness.industrycirrhosisCarcinomaSettore MED/09 - MEDICINA INTERNAPatient AcuityHepatocellularHepatitis C Chronicmedicine.diseaseLiver TransplantationTransplantationLiver functionbusinesscirrhositransplantationEuropean Journal of Clinical Investigation
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Activity of orally self-administered acetaldehyde in an operant/conflict paradigm in rats; involvement of cannabinoid cb1 receptors

2012

Acetaldehyde (ACD), ethanol first metabolite, interacts with the dopaminergic reward system, and with the neuropeptidergic transmission in the hypothalamus. Self-administration within operant conditioning is a valid model to investigate drug-seeking and drug-taking behaviour in rats. Cannabinoid CB1 receptors are involved in reinstatement of alcohol-seeking behaviour and of many other drugs of abuse (3). Accordingly, this study was aimed at the evaluation of: 1) the motivational properties of oral ACD in the induction and maintenance of an operant-drinking behaviour; 2) the onset of a relapse drinking behaviour, following ACD deprivation; 3) ACD effect in a conflict situation employing the …

Acetaldehyde CB1 receptor alcohol seeking behaviourSettore BIO/14 - Farmacologia
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Acetogenins from Annonaceae: Recent Progress in Isolation, Synthesis and Mechanisms of Action

2005

Covering: the literature from 1998 to 2004 The aim of the present review is to summarise the knowledge about newly isolated acetogenins (ACGs) in the last six years. It will also report the total syntheses that have allowed either the confirmation or the revision of some structures, together with the biological activities and mechanism of action of such interesting natural products. In fact, of the 417 isolated compounds reviewed, over 176 have been added during the period from 1998 to 2004.

AcetogeninsIsolation (health care)StereochemistryAnnonacinAnnonaceaeComputational biologyBiochemistryLactoneschemistry.chemical_compoundDrug DiscoverymedicineMolecular StructureTraditional medicinebiologyChemistryOrganic ChemistryGeneral Medicinebiology.organism_classificationAntineoplastic Agents PhytogenicAction (philosophy)Mechanism of actionAnnonaceaeAcetogeninFatty AlcoholsAnnonaceous Acetogeninsmedicine.symptomBullatacinChemInform
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Inhibitory effects on mitochondrial complex I of semisynthetic mono-Tetrahydrofuran acetogenin derivatives

2003

Modifications in the terminal alpha,beta-unsaturated gamma-methyl-gamma-lactone moiety or in the alkyl chain that links this terminal gamma-lactone with the alpha,alpha'-dihydroxylated THF system of the natural mono-tetrahydrofuranic acetogenins, annonacin and annonacinone, led to the preparation of eight semisynthetic derivatives. Their inhibitory effects on mitochondrial complex I is discussed and compared with that of the classical complex I inhibitor, rotenone.

AcetogeninsStereochemistryClinical BiochemistryRespiratory chainAnnonacinPharmaceutical ScienceBiochemistryChemical synthesisLactoneschemistry.chemical_compoundMultienzyme ComplexesDrug DiscoveryMoietyNADH NADPH OxidoreductasesEnzyme InhibitorsFuransMolecular BiologyTetrahydrofuranchemistry.chemical_classificationElectron Transport Complex IOrganic ChemistryRotenoneKineticschemistryAcetogeninMolecular MedicineFatty AlcoholsLactoneBioorganic &amp; Medicinal Chemistry Letters
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Renewable polyol obtained by microwave-assisted alcoholysis of epoxidized soybean oil: Preparation, thermal properties and relaxation process

2019

[EN] The soybean oil polyol (SOP) use as feedstock in the polyurethane industry has been recently emphasized due to its excellent resistance to hydrolysis, which is also applicable in coatings and thermal insulation. In this article, the SOP was obtained by a very fast microwave-assisted alcoholysis of epoxidized soybean oil (ESO). The preparation method, thermal properties, and relaxation process were evaluated. High yields as opening and consumption epoxy group and selectivity of 99.8 mol%, 985 mol%, and 71.2 mol% were obtained. Through titrations, nuclear magnetic resonance and gel permeation chromatography were identified parameters as 0.32 mg KOH.g(-1) acid number, 190 mg KOH.g(-1) hyd…

Acid valuefood.ingredientMaterials scienceThermal properties02 engineering and technologyDielectric relaxation spectroscopy010402 general chemistry01 natural sciencesSoybean oilGel permeation chromatographychemistry.chemical_compoundfoodMaterials Chemistry13.- Tomar medidas urgentes para combatir el cambio climático y sus efectosPhysical and Theoretical ChemistrySoybean oil polyolSpectroscopyPolyurethane021001 nanoscience & nanotechnologyCondensed Matter PhysicsAtomic and Molecular Physics and Optics0104 chemical sciencesElectronic Optical and Magnetic Materials02.- Poner fin al hambre conseguir la seguridad alimentaria y una mejor nutrición y promover la agricultura sostenibleEpoxidized soybean oil08.- Fomentar el crecimiento económico sostenido inclusivo y sostenible el empleo pleno y productivo y el trabajo decente para todos12.- Garantizar las pautas de consumo y de producción sostenibles07.- Asegurar el acceso a energías asequibles fiables sostenibles y modernas para todosChemical engineeringchemistryHydroxyl valueMAQUINAS Y MOTORES TERMICOS0210 nano-technologyGlass transitionMicrowave-assisted alcoholysisSaponification
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Evaluation of Antimicrobial Activity of Triphala Constituents and Nanoformulation

2020

The prevalence of nosocomial infections due to multidrug resistant (MDR) bacterial strains is associated with high morbidity and mortality. Folk medicine and ethnopharmacological data can provide a broad range of plants with promising antimicrobial activity. Triphala, an Ayurvedic formula composed of three different plants: Terminalia chebula Retz., Terminalia bellirica (Gaertn.) Roxb. (Combretaceae), and Phyllanthus emblica L. (Phyllanthaceae), is used widely for various microbial infections. Various extraction techniques were applied in the extraction of the biologically active constituents of Triphala in order to compare their efficiency. Microwave-assisted extraction (MAE) was shown to …

Active ingredient0303 health sciencesTraditional medicineArticle SubjectCetyl alcoholAntimicrobial01 natural sciencesDosage form0104 chemical sciencesTerminalia chebulaOther systems of medicine010404 medicinal & biomolecular chemistry03 medical and health scienceschemistry.chemical_compoundIngredientComplementary and alternative medicinechemistryCarvacrolTriphalaRZ201-999Research Article030304 developmental biologyEvidence-Based Complementary and Alternative Medicine
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Phase equilibrium for the systems diisopropyl ether, isopropyl alcohol+2,2,4-trimethylpentane and +n-heptane at 101.3kPa

2010

Abstract Consistent vapour–liquid equilibrium data for the ternary systems diisopropyl ether + isopropyl alcohol + 2,2,4-trimethylpentane and diisopropyl ether + isopropyl alcohol + n-heptane are reported at 101.3 kPa. The vapour–liquid equilibrium data have been correlated by Wilson, NRTL and UNIQUAC equations. The ternary systems do not present ternary azeotropes.

Activity coefficientTernary numeral systemUNIQUACGeneral Chemical EngineeringGeneral Physics and AstronomyThermodynamicsIsopropyl alcoholchemistry.chemical_compoundchemistryNon-random two-liquid modelDiisopropyl etherOrganic chemistry224-TrimethylpentanePhysical and Theoretical ChemistryTernary operationFluid Phase Equilibria
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Phase equilibria in the systems isobutyl alcohol+N,N-dimethylformamide, isobutyl acetate+N,N-dimethylformamide and isobutyl alcohol+isobutyl acetate+…

2005

Abstract Consistent vapor–liquid equilibria (VLE) were determined for the ternary system isobutyl alcohol (IBA) + isobutyl acetate (IBAc) + N,N-dimethylformamide (DMF) and two constituent binary systems at 101.3 kPa. The IBA + DMF system exhibits negative deviation from ideal behaviour and IBAc + DMF system deviates positively from ideal behaviour. The activity coefficients of the solutions were correlated with its composition by the Wilson, NRTL and UNIQUAC models. The ternary system is well predicted from binary interaction parameters.

Activity coefficientTernary numeral systemUNIQUACIsobutyl acetateGeneral Chemical EngineeringGeneral Physics and AstronomyAlcoholIsobutyl alcoholMedicinal chemistrychemistry.chemical_compoundchemistryPhase (matter)Non-random two-liquid modelOrganic chemistryPhysical and Theoretical ChemistryFluid Phase Equilibria
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Effect of pressure and the capability of 2-methoxyethanol as a solvent in the behaviour of a diisopropyl ether–isopropyl alcohol azeotropic mixture

2007

Abstract Consistent vapour–liquid equilibrium data for the binary and ternary systems of diisopropyl ether + isopropyl alcohol at 30 and 101.3 kPa and diisopropyl ether + 2-methoxyethanol, isopropyl alcohol + 2-methoxyethanol and diisopropyl ether + isopropyl alcohol + 2-methoxyethanol at 101.3 kPa are reported. The activity coefficients of the solutions were correlated with its composition using the Wilson, NRTL and UNIQUAC models. It is shown that the models allow a very good prediction of the phase equilibrium of the ternary system using the pertinent parameters of the binary systems. Moreover, the effect of pressure and the entrainer capability of 2-methoxyethanol were studied.

Activity coefficientUNIQUACTernary numeral systemChemistryGeneral Chemical EngineeringGeneral Physics and AstronomyIsopropyl alcoholchemistry.chemical_compoundNon-random two-liquid modelPhysical chemistryOrganic chemistryDiisopropyl etherBinary systemPhysical and Theoretical ChemistryIsopropylFluid Phase Equilibria
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