Search results for " approach"

showing 10 items of 1632 documents

A proposal for an anonymous living organ donation in Germany.

2003

Abstract In Germany, living organ donation of paired and usually not regenerating organs is restricted by law to related individuals, as well as persons who ‘obviously entertain an especially intimate personal relationship'. When this law was adopted in 1997, the intention of the legislator was to guarantee the free will of the donor and to exclude any trade of organs. Since then the transplantation of cadaveric organs has not increased. Additional organs were donated from living donors. However, for a number of reasons only a limited array of transplantation centers use living organ donation as a supply facing a steadily increasing number of patients with chronic renal failure. Living orga…

AdultMalemedicine.medical_specialtyTissue and Organ ProcurementLife qualityOrgan transplantationPathology and Forensic MedicineABO Blood-Group SystemTherapeutic approachLiving organ donationGermanyLiving DonorsMedicineHumansIntensive care medicineKidney transplantationbusiness.industryPersonal relationshipMiddle Agedmedicine.diseaseAltruismKidney TransplantationSurgeryTransplantationIssues ethics and legal aspectsBlood Group IncompatibilityChronic renal failurebusinessLegal medicine (Tokyo, Japan)
researchProduct

Teaching transurethral resection of the bladder: still a challenge?

2003

Abstract Objectives To report on our 2-year experience in teaching transurethral resection (TUR) of bladder tumors to five trainees. We analyzed their problems, as well as those of the teachers, and present our solutions. Methods Between April 2000 and March 2002, five residents and three members of the staff took part in a training program to teach TUR of the bladder. From a total of 692 patients with bladder tumors admitted for treatment to our department, 417 were selected for the study. These 417 had papillary tumors of small to medium size (maximum 25 mm in diameter). The mean patient age was 61 years (range 32 to 92) for men (n = 322; 77%) and 68.4 years (range 48 to 91) for women (n …

AdultMalemedicine.medical_specialtyUrologyUrinary BladdereducationPerforation (oil well)ResectionPostoperative ComplicationsPatient ageHumansMedicineProspective StudiesAgedAged 80 and overUrinary bladderSurgical approachbusiness.industryInternship and ResidencyMiddle AgedCarcinoma PapillarySurgerymedicine.anatomical_structureUrethraUrinary Bladder NeoplasmsGeneral SurgeryUrologic Surgical ProceduresEducation Medical ContinuingFemalebusinessTraining programComplicationProgram EvaluationUrology
researchProduct

Early clinical outcomes after small incision lenticule extraction surgery (SMILE)

2018

Abstract Purpose Dry eye is known to impact on clinical outcomes after laser vision correction and the use of a newer ‘all femtosecond laser’ surgical approach may be associated with less impact on the ocular surface post-operatively. The purpose of this study was to evaluate the early clinical outcomes and tear instability after the first small incision lenticule extraction (SMILE) cases undertaken by three surgeons at a single site in the UK. Methods Retrospective audit. Seventy-one eyes of 37 patients underwent SMILE surgery using the Zeiss VisuMax laser system (Carl Zeiss Meditec, Germany). Uncorrected and corrected distance visual acuity, spherical equivalent refraction, fluorescein en…

AdultMalemedicine.medical_specialtyVisual acuityDistance visual acuitygenetic structuresCorneal Surgery LaserCorneal StromaVisual AcuityRefraction Ocularlaw.invention03 medical and health sciences0302 clinical medicineSingle sitelawOphthalmologyMyopiamedicineHumansSmall incision lenticule extractionSmile surgeryRetrospective StudiesSurgical approachKeratometerbusiness.industryCorneal TopographyGeneral Medicineeye diseasesSurgeryOphthalmologyTears030221 ophthalmology & optometryFemaleLasers Excimersense organsmedicine.symptombusinessOcular surface030217 neurology & neurosurgeryOptometry
researchProduct

Long-term effects on adult attachment in German occupation children born after World War II in comparison with a birth-cohort-matched representative …

2016

Children born of war are a phenomenon of every conflict. At the end of World War II and thereafter, approximately 400,000 children were fathered by foreign soldiers and born to local women in Germany. Quantitative research on psychosocial consequences of growing up as German occupation child (GOC) has been missing so far.This study examines adult attachment and its association with current depression in GOC (N = 146) using self-report instruments: Adult Attachment Scale, Patient Health Questionnaire. Data were compared to a birth-cohort-matched representative sample of the German population (BCMS; N = 786).GOC differ in both attachment dimensions (less comfortable with closeness/intimacy, l…

AdultMalemedicine.medical_specialtyWorld War IIPopulationPsychological Techniques050109 social psychologyGermanLife Change Events03 medical and health sciences0302 clinical medicineGermanymedicineHumans0501 psychology and cognitive sciencesPsychiatryeducationChildObject Attachmenteducation.field_of_studyPovertyDepression05 social sciencesWorld War IIObject Attachmentlanguage.human_language030227 psychiatryPatient Health QuestionnairePsychiatry and Mental healthAdult Survivors of Child Adverse EventslanguageLife course approachFemaleGeriatrics and GerontologyPshychiatric Mental HealthPsychologyGerontologyPsychosocialAgingmental health
researchProduct

Angina bullosa haemorrhagica:a 14-year multi-institutional retrospective study from Brazil and literature review

2021

Background Angina bullosa haemorrhagica (ABH) is characterized by the recurrent appearance of blood blisters on the oral mucosa, mainly in adults' soft palate. In general, the blisters rupture spontaneously, lacking the necessity for biopsy. We report the clinical features of 23 ABH cases, emphasizing the clinical behavior and the management of these conditions. Material and Methods A retrospective descriptive cross-sectional study was performed. A total of 12,727 clinical records of oral and maxillofacial lesions from four dental services in Brazil were analyzed. Clinical data were collected from the clinical records and evaluated. Results The series comprised 12 males (52.2%) and 11 femal…

AdultMalemedicine.medical_specialtyclinical teachersAsymptomaticburnout syndromeTherapeutic approachAngina bullosa haemorrhagicaBlisterdental implantsBiopsymedicineHumansOral mucosaGeneral DentistryUNESCO:CIENCIAS MÉDICASAgedRetrospective StudiesOral Medicine and PathologySoft palatemedicine.diagnostic_teststudentsbusiness.industryResearchRetrospective cohort studyMiddle Agedmedicine.diseaseOral HemorrhageDermatologyCross-Sectional Studiesmedicine.anatomical_structuredental educationOtorhinolaryngologyEtiologyFemaleSurgerymedicine.symptomMouth DiseasesbusinessBraziloral surgery
researchProduct

Omalizumab (Xolair®) improves quality of life in adult patients with allergic asthma: a review

2003

Abstract Physicians are increasingly aware that asthma causes significant impairment of the patient's physical, psychological, and social well-being. Whilst standard clinical endpoints provide significant information on airway status during treatment, it is important to determine whether such improvements overcome the functional impairment that patients have to deal with on a daily basis. As such, assessment of health-related quality of life (QoL) is an important aspect of asthma management in clinical practice. Omalizumab (Xolair ® ) is a recombinant humanized monoclonal anti-immunoglobulin E (IgE) antibody that represents a new therapeutic approach to IgE-mediated diseases such as allergi…

AdultPulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentOmalizumabAntibodies Monoclonal HumanizedImmunoglobulin EPlaceboTherapeutic approachDouble-Blind MethodQuality of lifeInternal medicinemedicineClinical endpointHumansAnti-Asthmatic Agentsanti-IgEChildquality of life.AgedAsthmabiologybusiness.industryRespiratory diseaseAntibodies MonoclonalMiddle Agedmedicine.diseaseAsthmaAntibodies Anti-IdiotypicQuality of Lifebiology.proteinPhysical therapyomalizumabbusinessAttitude to Healthallergic asthmamedicine.drugRespiratory Medicine
researchProduct

The influence of organizational factors on road transport safety

2018

Road transport safety is a major concern across Europe due to the human and socio-economic costs associated with work-related traffic accidents. Traditional approaches have adopted regulatory and technical measures to prevent road accidents leaving aside the organizational factors that might contribute to road transport safety. However, contemporary sociotechnical systems theory acknowledges the need to take into account organizational factors. This study adopts a sociotechnical approach and it examines the relationship between a number of organizational factors (organizational learning and training) and road traffic accidents in the organizations under study. Our sample was composed of 107…

AdultSociotechnical systemHealth Toxicology and MutagenesisControl variablelcsh:MedicinePoison controlTransportationSample (statistics)ArticleOccupational safety and healthorganizational learning0502 economics and businessInjury preventionHumansLearningTrainingroad transport safetyRoad transport safetysociotechnical approachOrganizations050210 logistics & transportationtrainingPsicologia socialbusiness.industrySeguretat viàrialcsh:R05 social sciencesAccidents TrafficOrganizational learningPublic Health Environmental and Occupational HealthHuman factors and ergonomicsTraffic safetyEnvironmental economicsAprenentatge organitzatiuOrganizational CultureSociotechnical approachSpainOrganizational learningSeguridad vialAprendizaje organizacionalSafetybusiness050203 business & management
researchProduct

Successful treatment of a young patient with locally advanced clear cell adenocarcinoma of the uterine cervix undergoing chemoradiation followed by r…

2014

Clear cell adenocarcinoma (CCAC) of the uterine cervix is a rare variant of cervical adenocarcinoma accounting for approximately 4-9% of this disease. Given the rarity of this pathological entity, the optimal treatment management is far from being defined. Earlier evidence suggested that the prognosis of patients bearing cervical CCAC is worse than with other histotypes, thus making the investigation of multimodal treatment strategies clinically worthwhile. Herein, we report the first case of locally advanced, large size cervical CCAC in a young woman who was triaged to concomitant chemoradiotherapy followed by radical surgery and experienced a pathologically assessed optimal response to th…

Adultmedicine.medical_specialtyAdvanced clear cell adenocarcinomaUterine Cervical NeoplasmRadical surgeryUterine Cervical NeoplasmsDisease-Free SurvivalObstetrics and gynaecologyadenocarcinoma uterine cervixUterine cervixmedicineHumansCombined Modality TherapyClear-cell adenocarcinomaRadical surgeryPathologicalSettore MED/08 - ANATOMIA PATOLOGICAbusiness.industryObstetrics and GynecologyMultimodal therapyChemoradiotherapy Adjuvantmedicine.diseaseMultimodal approachCombined Modality TherapyImmunohistochemistryMagnetic Resonance ImagingSurgeryChemoradiationReproductive MedicineAdenocarcinomaFemalebusinessChemoradiotherapyAdenocarcinoma Clear CellHuman
researchProduct

Unexpected high frequency of genital involvement in women with clinical and hostological features of oral lichen planus

2006

The main aims of this cross-sectional study were: (i) to assess the frequency of genital (vulval) lichen planus (VLP) and vulval lichen sclerosus (VLS) in women affected with oral lichen planus (OLP), regardless of the genital symptoms reported; and (ii) to verify whether any demographic, clinical, or histological features of OLP are associated with a higher risk of vulvo-vaginal involvement. Fifty-five women, presenting OLP, consecutively underwent gynaecological examination and, if they demonstrated positive clinical signs of VLP, underwent biopsy. After a drop-out of 14 subjects, 31/41 (75.6%) were found to have signs of genital involvement, of which 13/31 (44.0%) were asymptomatic. Foll…

Adultmedicine.medical_specialtyDermatologyLichen sclerosusSettore MED/08 - Anatomia PatologicaAsymptomaticVulvar Lichen Sclerosusoral lichen planuTherapeutic approachstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheBiopsyoral lichen planus; genital lichen planusgenital lichen planusMedicineHumansSex organAgedAged 80 and overmedicine.diagnostic_testbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseDermatologySettore MED/40 - Ginecologia E Ostetriciastomatognathic diseasesGynaecological examinationCross-Sectional StudiesOral lichen planusFemaleVulvar DiseasesMultivariate statisticalmedicine.symptombusinessLichen Planus Oral
researchProduct

A comparison of transhiatal and transthoracic resections on the prognosis in patients with squamous cell carcinoma of the esophagus

2006

The aim of this study was to investigate the long-term prognosis for squamous cell carcinoma of the esophagus treated either by the transhiatal (TH) or by the transthoracic (TT) operative approach.Two hundred and twenty-nine patients (median age: 56 (29-84) years) with squamous cell carcinoma of the esophagus underwent esophageal resection between September 1985 and April 2004. In 70 patients, the transhiatal approach and in 159, the transthoracic approach was applied. An extended mediastinal lymph-node dissection was only carried out in the course of the transthoracic technique.Demographic data and tumor stages were comparable in both groups. A significantly better long-term survival was o…

Adultmedicine.medical_specialtyEsophageal NeoplasmsCarcinomamedicineHumansBasal cellIn patientEsophagusSurvival rateTransthoracic approachAgedAged 80 and overbusiness.industryGeneral MedicineMiddle AgedPrognosismedicine.diseaseSurgeryEsophagectomySurvival RateDissectionmedicine.anatomical_structureOncologyLymphatic MetastasisCarcinoma Squamous CellSurgeryLymphbusinessEuropean Journal of Surgical Oncology (EJSO)
researchProduct