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showing 10 items of 2302 documents

Oxytocin reduces romantic rejection-induced pain in online speed-dating as revealed by decreased frontal-midline theta oscillations

2021

Abstract Background Romantic rejection is an emotionally distressful experience profoundly affecting life, possibly leading to mental illness or suicide. Oxytocin (OT) is a neuropeptide widely implicated in reducing physical pain and negative emotions; however, whether OT has an effect on reducing intense social pain (e.g., romantic rejection) remains unknown. Here, we tested the effect of OT on social pain and investigated its role in the outcome evaluation phase of social decision-making. Methods Electroencephalographic recordings were obtained between August 2nd and October 20th, 2020 in Shenzhen University from 61 healthy participants in a double-blind, placebo-controlled study with a b…

medicine.medical_specialtyEndocrinology Diabetes and MetabolismPainElectroencephalographyAudiologyOxytocinSomatosensory systemEndocrinologymedicineHumansAssociation (psychology)Biological PsychiatryAnterior cingulate cortexInternetmedicine.diagnostic_testSupplementary motor areaEndocrine and Autonomic Systemsbusiness.industryCourtshipBrainElectroencephalographyMental illnessmedicine.diseasePsychiatry and Mental healthDistressmedicine.anatomical_structureOxytocinRejection Psychologybusinessmedicine.drugPsychoneuroendocrinology
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COVID‐19 and exacerbation of dermatological diseases: A review of the available literature

2021

Abstract Since the emergence of the new coronavirus disease 19 (COVID‐19) pandemic, there has been a concern for the patients with chronic autoimmune diseases including dermatological conditions over the potential exacerbation of these underlying conditions after infection with severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV2). We performed a systematic review to evaluate presentations, postinfection change in the manifestation, diagnosis, and management of flare‐ups of underlying dermatologic disease in patients with COVID‐19. A total of 17 articles were recovered reporting on flare‐ups of dermatological disease including pemphigus vulgaris, psoriasis, subacute cutaneous lupus er…

medicine.medical_specialtyExacerbationShort ReportDiseaseSclerodermaSubacute cutaneous lupus erythematosusexacerbationShort ReportsCOVID‐19PsoriasismedicineHumansflare‐upworseningskin and connective tissue diseasesPandemicsSARS‐Cov2business.industrySARS-CoV-2Pemphigus vulgarispemphigusCOVID-19General MedicinepsoriasisAlopecia areatamedicine.diseaseDermatologydermatologyPemphigusRNA ViralbusinessDermatologic Therapy
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Capacidad de perdonar en pacientes en tratamiento psiquiátrico y psicológico ambulatorio

2008

Data gathered administering SCL-90-R (Spanish version) and a scale developed to assess Capacity to Forgive (CAPER) are presented. The study was carried out on a sample of 107 outpatients from Buenos Aires city and its suburban area (64 % women, 36 % men; average age: 36 years old) from a private Mental Health Center. A significant statistical negative correlation (Pearson r) was found between forgiveness and presence of psychopathological symptoms.

medicine.medical_specialtyGeneral Chemical EngineeringmedicineSuburban areaSpanish versionNegative correlationPsychiatryPsychologySocial psychologyPsicodebate
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Dynamic angiopoietin-2 assessment predicts survival and chronic course in hospitalized patients with COVID-19

2021

Key Points Three-day change in angiopoietin-2 levels predicts COVID-19 in-hospital mortality, whereas the 10-day trend is associated with chronic lung disability. Angiopoietin-2 may play an important pathogenic role in patients with COVID-19, and it could be a target for new treatments.

medicine.medical_specialtyMultivariate analysis20CD34Risk Factors ...030204 cardiovascular system & hematologyGastroenterologyAntiviral AgentsAngiopoietin-203 medical and health sciences0302 clinical medicineRisk FactorsVascular BiologyInternal medicinemedicineHumans030212 general & internal medicineHospital MortalitySurvival rateProportional Hazards ModelsAntiviral AgentLungReceiver operating characteristicbusiness.industryProportional hazards modelSARS-CoV-2Interleukin-6Risk FactorHazard ratioCOVID-19HematologyBiomarker32Confidence intervalCOVID-19 Drug TreatmentHospitalizationSurvival RateAngiopoietin-2; Antiviral Agents; Area Under Curve; Biomarkers; COVID-19; Hospital Mortality; Hospitalization; Humans; Interleukin-6; Proportional Hazards Models; ROC Curve; Risk Factors; SARS-CoV-2; Survival Ratemedicine.anatomical_structureROC CurveArea Under Curvecardiovascular systemProportional Hazards ModelbusinessBiomarkersHuman
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Regulation of NT Receptors after Chronic Treatment with Typical and Atypical Neuroleptic Drugs

1991

Neurotensin is a tridecapeptide, which produces central effects such as hypotension, hypothermia, muscle relaxation, analgesia, antinociception, and reduces locomotor activity (Nemeroff et al., 1977). In the recent years, several lines of evidences indicated the great importance of the dopamine (DA)- neurotensin (NT) interaction taking place mostly in the mesolimbocortical areas, both at cell bodies (A10 DA-ergic group located in the ventral tegmental area -VTA-) and nerve terminal level (cerebral cortex, n. accumbens, olfactory tubercle, ventral n. caudato-putamen) (Quirion, 1983; Nemeroff, et al., 1984; Nemeroff, 1986). Immunocytochemical data indicated the presence of NT-like immunoreact…

medicine.medical_specialtyOlfactory tubercleBiologyVentral tegmental areaMidbrainchemistry.chemical_compoundEndocrinologymedicine.anatomical_structurenervous systemchemistryCerebral cortexDopamineInternal medicineBasal gangliamedicineNeurotensin receptorNeurotensinmedicine.drug
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Endovascular management of a giant symptomatic gluteal artery aneurysm with selective arterial embolization

2017

A 78-year-old female presented to our department with pain and swelling in the left gluteal region. Physical examination revealed a large tender swelling in the left gluteal area simulating an abscess. However, pulsation was observed over the swelling that raised the suspicion of a vascular lesion. Therefore, contrast-enhanced computed tomography (CT) was done before trying any intervention. The scan demonstrated a large aneurysm originating from the left superior gluteal artery measuring 65 mm × 38 mm with a small intra-pelvic component and large extra-pelvic component in the gluteal area ( Figure 1 ).

medicine.medical_specialtyPhysical examination[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine030204 cardiovascular system & hematology[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicine03 medical and health sciences0302 clinical medicineAneurysmmedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingRadiology Nuclear Medicine and imaging030212 general & internal medicineLeft gluteal regionGluteal ArteryAbscessLetter to the EditorComputingMilieux_MISCELLANEOUSmedicine.diagnostic_test[ INFO.INFO-IM ] Computer Science [cs]/Medical Imagingbusiness.industryArterial Embolizationmedicine.diseaseLeft superior gluteal arterySurgerybody regionsRadiologybusinessGluteal area
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Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men

2016

As training experience increases it becomes more challenging to induce further neuromuscular adaptation. Consequently, strength trainers seek alternative training methods in order to further increase strength and muscle mass. One method is to utilize accentuated eccentric loading, which applies a greater external load during the eccentric phase of the lift as compared to the concentric phase. Based upon this practice, the purpose of this study was to determine the effects of 10 weeks of accentuated eccentric loading vs. traditional isoinertial resistance training in strength-trained men. Young (22 ± 3 years, 177 ± 6 cm, 76 ± 10 kg, n = 28) strength-trained men (2.6 ± 2.2 years experience) w…

medicine.medical_specialtyPhysiologyIsometric exerciseConcentriclcsh:PhysiologyMuscle hypertrophy03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicineCross-sectional areaMedicineEccentricta315Leg pressOriginal Researcheccentric-overloadlcsh:QP1-981business.industryWork (physics)Resistance trainingResistance Trainingvoluntary activationTwitch interpolationHypertrophy030229 sport sciencesM-wavecross-sectional areaCardiologyPhysical therapyresistance traininghypertrophybusiness030217 neurology & neurosurgeryFrontiers in Physiology
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Developmental dyslexia: atypical cortical asymmetries and functional significance

2000

Using brain magnetic resonance imaging, we measured in 16 young developmental dyslexic adults and 14 age-matched controls cortical asymmetries of posterior language-related areas, including Planum temporale and parietal operculum cortical ribbon, and of the inferior frontal region related in the left hemisphere to speech processing. In addition, we assessed the sulcal morphology of the inferior frontal gyrus in both groups according to a qualitative method. The dyslexic subjects also performed specific tasks exploring different aspects of phonological and lexical-semantic processes. Results showed that: (1) contrary to most results reported in the literature, there is a lack of any morpholo…

medicine.medical_specialtyPlanum temporaleDyslexiaParietal lobeInferior frontal gyrusPhonological deficitAudiologymedicine.diseasebehavioral disciplines and activitiesLateralization of brain functionNeurologyFrontal lobemedicineNeurology (clinical)medicine.symptomBroca's areaPsychologyCognitive psychologyEuropean Journal of Neurology
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Inverse association between type 2 diabetes and aortic root dimension in hypertensive patients

2017

Background Some data support the concept that aortic root diameter (ARD) in hypertension may be regarded as a marker of subclinical organ damage. The impact of type 2 diabetes mellitus (DM) on cardiac structure and function is known, although the relationship between DM and ARD is not clear. The aim of our study was to evaluate the influence of DM on ARD in hypertensive patients. Methods We enrolled 1693 hypertensive patients (aged 63.7 ± 9.6 years). The population was divided into two groups: the first one with DM (n = 747) and the second one without DM (n = 946). ARD was measured by echocardiography at level of Valsalva's sinuses using echocardiography M-mode tracings. It was considered a…

medicine.medical_specialtySettore MED/09 - Medicina InternaPopulationType 2 diabetes030204 cardiovascular system & hematologyDoppler imagingType 2 diabeteSettore MED/13 - Endocrinologia03 medical and health sciences0302 clinical medicineBayesian multivariate linear regressionInternal medicinemedicine030212 general & internal medicineeducationSubclinical infectionBody surface areaeducation.field_of_studybusiness.industryConfoundingType 2 Diabetes Mellitusmedicine.diseaseCardiovascular riskSettore MED/11 - Malattie Dell'Apparato CardiovascolareEndocrinologyEchocardiographyHypertensionCardiologyCardiology and Cardiovascular MedicinebusinessAortic root diameter
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2018

The pre-supplementary motor area (pre-SMA) is engaged in speech comprehension under difficult circumstances such as poor acoustic signal quality or time-critical conditions. Previous studies found that left pre-SMA is activated when subjects listen to accelerated speech. Here, the functional role of pre-SMA was tested for accelerated speech comprehension by inducing a transient "virtual lesion" using continuous theta-burst stimulation (cTBS). Participants were tested (1) prior to (pre-baseline), (2) 10 min after (test condition for the cTBS effect), and (3) 60 min after stimulation (post-baseline) using a sentence repetition task (formant-synthesized at rates of 8, 10, 12, 14, and 16 syllab…

medicine.medical_specialtySpeech perceptionRepetition (rhetorical device)Supplementary motor areaGeneral Neurosciencemedia_common.quotation_subject05 social sciencesCTBSContext (language use)Audiology050105 experimental psychologyTask (project management)03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurePerceptionotorhinolaryngologic diseasesmedicine0501 psychology and cognitive sciencesPsychology030217 neurology & neurosurgerySentencemedia_commonFrontiers in Neuroscience
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