Search results for " assembly."

showing 10 items of 283 documents

Noncovalent assembly of functional groups on calix[4]arene molecular boxes

1997

Calix[4]arenes diametrically substituted at the upper rim with two melamine units spontaneously form well-defined box-like assemblies in the presence of two equivalents of 5,5-diethylbarbituric acid. These assemblies, consisting of nine different components, are held together by 36 hydrogen bonds and are stable in apolar solvents at concentrations of up to 10-4M. This paper reports the first X-ray crystal structure, and the MALDI TOF mass spectra together with the complete 1H NMR spectroscopic characterization of these hydrogen-bonded assemblies. The crystal structure clearly shows that the assemblies are stereogenic, as a result of the antiparallel orientation of the two rosette motifs. Fu…

Steric effectsNoncovalent assemblyMolecular boxesChemistryHydrogen bondStereochemistryOrganic ChemistrySupramolecular chemistryGeneral ChemistryAntiparallel (biochemistry)CatalysisSupramolecular ChemistryStereocenterHydrogen bondsCrystallographyIntramolecular forceCalixareneProton NMRCalixarenesChemistry : a European journal
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Thermomechanical analysis supporting the preliminary engineering design of DONES target assembly

2018

Abstract The design of the Demo Oriented NEutron Source (DONES) is the main objective of the Work Package Early Neutron Source (WPENS) of EUROfusion Power Plant Physics and Technology (PPPT) programme. DONES is an IFMIF-based neutron source with the goal of testing and qualifying candidate materials to be used in DEMO and future fusion power plants. In the framework of these activities, a research campaign has been carried out at the University of Palermo, in close cooperation with ENEA labs, in order to assess the thermomechanical performances of the DONES target system, endowed with an integrated Target Assembly (TA) when it undergoes the thermomechanical loads typical of its nominal oper…

Structural materialPower stationMechanical EngineeringNuclear engineeringFusion power7. Clean energy01 natural sciencesThermomechanicFinite element method010305 fluids & plasmasNuclear Energy and EngineeringTarget assemblyLinearization0103 physical sciencesIFMIFNeutron sourceDONESGeneral Materials ScienceMaterials Science (all)010306 general physicsEngineering design processFEM analysiSettore ING-IND/19 - Impianti NucleariBeam (structure)Civil and Structural EngineeringFusion Engineering and Design
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THE HUMAN RIGHT TO HEALTH: A RETROSPECTIVE ANALYSIS AFTER 70 YEARS OF INTERNATIONAL RECOGNITION

2018

In 1948, the General Assembly of the United Nations adopted the first international text recognising universal human rights for all; the Universal Declaration of Human Rights. Article 25 recognises the right to an adequate standard of living, which includes the right to health and medical care. On the occasion of the 70th anniversary of the Declaration, this article presents an overview of the main developments that have been made towards understanding the content and implications of the right to health, as well as an analysis of some specific advancements that aim to facilitate the enforcement thereof. These include: a) the implication of private entities as responsible for right to health…

Sustainable developmentIndividual ComplaintsSociology and Political ScienceRight to healthHuman rightsUnited NationsHuman Rights ObligationsGeneral assemblymedia_common.quotation_subjectUniversal Health CoverageDeclarationRight to an adequate standard of livingPublic administrationRight to HealthPolitical sciencelcsh:K1-7720Political Science and International RelationsCultural rightslcsh:Law in general. Comparative and uniform law. JurisprudenceEnforcementLawmedia_commonAge of Human Rights Journal
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Analysis of the thermo-mechanical behaviour of IFMIF Target Assembly

2013

Target Assembly Thermo-mechanicsIFMIFNUCLEAR FUSION IFMIFSettore ING-IND/19 - Impianti Nucleari
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Epigenetic Regulation of Early- and Late-Response Genes in Acute Pancreatitis

2015

Abstract Chromatin remodeling seems to regulate the patterns of proinflammatory genes. Our aim was to provide new insights into the epigenetic mechanisms that control transcriptional activation of early- and late-response genes in initiation and development of severe acute pancreatitis as a model of acute inflammation. Chromatin changes were studied by chromatin immunoprecipitation analysis, nucleosome positioning, and determination of histone modifications in promoters of proinflammatory genes in vivo in the course of taurocholate-induced necrotizing pancreatitis in rats and in vitro in rat pancreatic AR42J acinar cells stimulated with taurocholate or TNF-α. Here we show that the upregulat…

Taurocholic AcidTranscriptional Activation0301 basic medicineChromatin ImmunoprecipitationImmunologyAcinar CellsBiologyMethylationChromatin remodelingEpigenesis GeneticHistones03 medical and health sciences0302 clinical medicineHistone methylationAnimalsImmunology and AllergyNucleosomeEpigeneticsPromoter Regions GeneticEarly Growth Response Protein 1Histone AcetyltransferasesInflammationPancreatitis Acute NecrotizingTumor Necrosis Factor-alphaDNA HelicasesNuclear ProteinsAcetylationHistone acetyltransferaseChromatin Assembly and DisassemblyRatsChromatin030104 developmental biologyHistoneGene Expression Regulation030220 oncology & carcinogenesisbiology.proteinCancer researchProtein Processing Post-TranslationalChromatin immunoprecipitationTranscription FactorsThe Journal of Immunology
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Non-Linear Hysteretic Instability in Rotating Machinery

2013

The destabilizing influence of the shaft hysteresis on the supercritical whirl of rotating machines can be efficiently counterbalanced by proper external dissipative sources in the supports and/or anisotropic suspension systems. The hysteretic effect may be treated either by dry or viscous models obtaining different but somehow similar results in the hypothesis of small dissipation levels. Thus the linear viscous assumption is often accepted as a crude approximation for a straightforward analysis of the whirling instability. Nevertheless the internal friction should be regarded most likely as non-linear and could be approximated for example by Coulombian models taking thus into account also the releasing effect of some shrink-fit coupling present in the mechanical assembly.
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Pannello precompresso di vetromattoni assemblati a secco per la realizzazione di involucri traslucidi

2012

L’invenzione riguarda la realizzazione di un pannello di vetromattoni montati “a secco” -da impiegare per la realizzazione di involucri edilizi traslucidi anche nel caso di edifici alti- che è in grado di rispondere adeguatamente alle sollecitazioni orizzontali (quali quelle dovute a vento e sisma) grazie all’applicazione della tecnica della precompressione mondirezionale. Per offrire una risposta ai limiti imposti dalla tecnica di assemblaggio tradizionale dei vetromattoni (“ad umido”), l’applicazione della precompressione consente, infatti, di dare ai pannelli preassemblati “a secco” una rigidezza adeguata anche in direzione normale al loro piano di posa, sfruttando le buone caratteristic…

The invention is related to the construction of a glassblock panel “dry assembled” that can be used to build translucent building envelope even in high-rise buildings. This panel is able to contrast the horizontal actions due to wind and earthquake by means of the application of unidirectional pre-stressing technique. To overcame the limits due to the “wet assembly” system traditionally used to assemble the glassblocks the use of prestressing technique allow the panels to have an adequate mechanical resistance against the actions perpendicular to their installation plane. In this configuration the mechanical resistance of the glassblocks is exploited. The unidirectional prestressing (along the prevalent dimension of the panel) is obtained through the grip of the nuts inserted in the steel bars that are housed inside the glassblocks supporting profiles positioned in the vertical cavities between the glassblocks and passing through the horizontal profiles useful to separate glassblock rows from each other. The proper nuts grip opposing to the steel plates positioned at the top and bottom of the panel allow to prestress the panel. The steel plate are positioned on a plastic plate fixed to the lateral faces of the glassblocks by means of resins.Settore ICAR/10 - Architettura Tecnica
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Pharmaceutical properties of supramolecular assembly of co-loaded cardanol/triazole-halloysite systems

2015

Halloysite nanotubes were explored as drug carrier for cardanol, which is considered as a promising natural anticancer active species. To this aim, besides the pristine nanoclay, a chemical modification of the nanocarrier was performed by attaching triazolium salts with different hydrophobicity at the outer surface of the hollow nanotubes. The interaction between cardanol and nanotubes was highlighted in solution by HPLC. This method proved the loading of the drug into the nanotubes. The solid dried complexes formed by pristine and modified halloysite with the cardanol were characterized by IR spectroscopy, thermogravimetric analysis as well as water contact angle to evidence the structure,…

Thermogravimetric analysisMaterials scienceCell SurvivalPharmaceutical ScienceAntineoplastic Agentsengineering.materialHalloysiteSupramolecular assemblyContact anglePhenolsCell Line TumorOrganic chemistryHumansHEPATOCELLULAR CARCINOMASettore CHIM/02 - Chimica FisicaCardanolHALLOYSITEDrug CarriersHepatocellular carcinoma Cardanol Drug carrier Halloysite HPLCNanotubesChemical modificationSettore CHIM/06 - Chimica OrganicaTriazolesDrug LiberationChemical engineeringengineeringMicroscopy Electron ScanningSettore BIO/14 - FarmacologiaClayAluminum SilicatesNanocarriersHPLCDrug carrierCARDANOLDRUG CARRIER
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The anion impact on the self-assembly of naphthalene diimide diimidazolium salts

2017

Naphthalene diimide diimidazolium salts differing in the anion nature were synthesized and their properties as well as their self-assembly behaviour were investigated. In particular, we took into consideration the N,N′-bis-(1-octyl-3-propylimidazolium)-naphthalene diimide cations and anions differing in size, shape and coordination abilities like [I−], [BF4−] and [NTf2−]. After determination of thermal behaviour, using differential scanning calorimetry and thermal gravimetric analysis, the electrochemical stability and redox properties were assessed using cyclic voltammetry. The self-assembly behaviour of the salts was investigated using concentration and temperature-dependent spectroscopic…

Thermogravimetric analysiselectrochemical stabilityInorganic chemistry02 engineering and technology010402 general chemistryElectrochemistryNaphthalene diimide01 natural sciencesRedoxCatalysischemistry.chemical_compoundDifferential scanning calorimetryDiimideredox propertiesMaterials Chemistryhermal gravimetric analysisIsodesmic reactiondiimidazolium saltGeneral Chemistryself assemblySettore CHIM/06 - Chimica Organica021001 nanoscience & nanotechnologyFluorescence0104 chemical scienceschemistryCyclic voltammetry0210 nano-technologyhermal gravimetric analysis;electrochemical stability;redox properties
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Supramolecular diversity and magnetic properties of novel heterometallic Cu(II)/Cr(III) complexes prepared from copper powder, Reineckes salt and eth…

2009

Abstract Three novel heterometallic complexes [Cu(en) 2 Cr(NCS) 4 (NH 3 ) 2 ][Cr(NCS) 4 (NH 3 ) 2 ] · 6dmf ( 1 ), [Cu(en) 2 Cr(NCS) 4 (NH 3 ) 2 ](OAc) ( 2 ) and [{Cu(en) 2 } 3 {Cr(NCS) 4 (NH 3 ) 2 } 2 (NCS) 2 ](NCS) 2 ( 3 ) have been synthesized in a one-pot reaction from copper powder, Reineckes salt, NH 4 X [X −  = OAc − ( 2 ), NCS − ( 3 )] in a dmf ( 1 ) or CH 3 CN ( 2 , 3 ) solution of ethylenediamine (en). X-ray studies showed that 1 and 2 consist of cationic polymeric chains, formed by Cu ( en ) 2 2 + and Cr ( NCS ) 4 ( NH 3 ) 2 - building blocks that bridged through thiocyanate anions. In both complexes, distinct hydrogen bonds are present and serve to increase the dimensionality of …

ThiocyanateHydrogen bondChemistryStereochemistrySupramolecular chemistryCationic polymerizationchemistry.chemical_elementEthylenediamineCopperSupramolecular assemblyInorganic ChemistryCrystallographychemistry.chemical_compoundChromiumMaterials ChemistryPhysical and Theoretical ChemistryInorganica Chimica Acta
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