Search results for " augmentation"

showing 10 items of 116 documents

Variable association of 24-h peripheral and central hemodynamics and stiffness with hypertension-mediated organ damage: the VASOTENS Registry.

2020

Objective In this analysis of the telehealth-based Vascular health ASsessment Of The hypertENSive patients Registry, we checked how 24-h central and peripheral hemodynamics compare with hypertension-mediated organ damage (HMOD). Methods In 646 hypertensive patients (mean age 52 ± 16 years, 54% males, 65% treated) we obtained ambulatory brachial and central SBP and pulse pressure (PP), SBP, and PP variability, pulse wave velocity and augmentation index with a validated cuff-based technology. HMOD was defined by an increased left ventricular mass index (cardiac damage, evaluated in 482 patients), an increased intima-media thickness (vascular damage, n = 368), or a decreased estimated glomerul…

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaPhysiologyarterial stiffness augmentation index blood pressure blood pressure telemonitoring central arterial pressure hypertension pulse wave velocity vascular biomarkersRenal functionHemodynamicsBlood Pressure030204 cardiovascular system & hematologyPulse Wave AnalysisKidneyCarotid Intima-Media Thickness03 medical and health sciences0302 clinical medicineInternal medicineInternal MedicinemedicineHumans030212 general & internal medicineRegistriesPulse wave velocityAgedSettore MED/14 - Nefrologiabusiness.industryHemodynamicsBlood Pressure DeterminationOdds ratioBlood Pressure Monitoring AmbulatoryMiddle Agedmedicine.diseasePulse pressureBlood pressureAmbulatoryHypertensionCardiologyArterial stiffnessFemaleCardiology and Cardiovascular MedicinebusinessGlomerular Filtration RateJournal of hypertension
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Transcrestal sinus lift and implant placement using the sinus balloon technique

2011

Objective: A description is made of transcrestal sinus lift using the sinus balloon technique, evaluating the bone height achieved and implant success one year after prosthetic loading. Material and method: Between January and July 2007, transcrestal sinus lift using the sinus balloon technique for dental implant placement was carried out in 6 patients. A panoramic X-ray study and maxillary computed tomography scan were carried out before the operation, in order to discard possible sinus pathology. During the intervention, the integrity of the sinus membrane was evaluated using a Medi Pack Pal endoscope (Farol Store and Co., Tuttlingen, Germany), and the intraoperative complications were an…

AdultMalemedicine.medical_specialtySinus Floor AugmentationEndoscopemedicine.medical_treatmentPerforation (oil well)Sinus Floor AugmentationDentistrySinus liftBalloonmedicineHumansDental implantGeneral DentistrySinus (anatomy)business.industryEquipment DesignMiddle Aged:CIENCIAS MÉDICAS [UNESCO]SurgeryDental Implantationmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASResearch-ArticleSurgeryImplantOral Surgerybusiness
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Osteotomy in direct sinus lift. A comparative study of the rotary technique and ultrasound

2011

Purpose: The present study investigates sinus membrane rupture in direct maxillary sinus lift with the rotary technique and with ultrasound, examining the survival of implants placed after sinus augmentation, and analyzing the bone gain obtained after the operation and 12 months after placement of the prosthetic restoration. Material and Methods: A retrospective study was made of 45 patients requiring maxillary sinus lift or augmentaMethods: A retrospective study was made of 45 patients requiring maxillary sinus lift or augmentaethods: A retrospective study was made of 45 patients requiring maxillary sinus lift or augmentation for implant-prosthetic rehabilitation. Use was made of the handp…

AdultMalemedicine.medical_specialtySinus Floor AugmentationMaxillary sinusmedicine.medical_treatmentDentistrySinus liftSinus Floor AugmentationOsteotomymedicineHumansOstectomyGeneral DentistrySinus (anatomy)AgedRetrospective Studiesbusiness.industryUltrasoundMiddle Aged:CIENCIAS MÉDICAS [UNESCO]SurgeryOsteotomymedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleImplantOral Surgerybusiness
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Bone Marrow Concentrate and Bovine Bone Mineral for Sinus Floor Augmentation

2011

Purpose: The purpose of this work was to evaluate the potential of substituting autogenous bone (AB) by bone marrow aspirate concentrate (BMAC). Both AB and BMAC were tested in combination with a bovine bone mineral (BBM) for their ability of new bone formation (NBF) in a multicentric, randomized, controlled, clinical and histological noninferiority trial.Materials and Methods: Forty-five severely atrophied maxillary sinus from 26 patients were evaluated in a partial cross-over design. As test arm, 34 sinus of 25 patients were augmented with BBM and BMAC containing mesenchymal stem cells. Eleven control sinus from 11 patients were augmented with a mixture of 70% BBM and 30% AB. Biopsies wer…

AdultMalemedicine.medical_specialtySinus Floor AugmentationOSTEOGENIC DIFFERENTIATIONBone RegenerationMaxillary sinusBiomedical EngineeringSinus Floor AugmentationBioengineeringBiochemistryMAXILLARY SINUSlaw.inventionMESENCHYMAL STEM-CELLSBIO-OSSBiomaterialsRandomized controlled trialTISSUE-ENGINEERED BONEBone MarrowOsteogenesislawmedicineAnimalsHumansSingle-Blind MethodSinus (anatomy)AgedIMPLANT PLACEMENTHYDROXYAPATITE CERAMICSBone TransplantationIntention-to-treat analysisPOROUS HYDROXYAPATITEbusiness.industryIN-VITROMiddle AgedSurgeryAUTOGENOUS BONEImplant placementBovine bonemedicine.anatomical_structureBone SubstitutesCattleFemaleBone marrowbusinessTissue Engineering. Part A
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Nanocrystalline Hydroxyapatite-Based Material Already Contributes to Implant Stability After 3 Months: A Clinical and Radiologic 3-Year Follow-up Inv…

2014

The present study reports on a 3-year clinical and radiologic follow-up investigation of dental implants placed 3 and 6 months after sinus augmentation in 14 patients. Augmentation was performed with a synthetic bone substitute material composed of nanocrystalline hydroxyapatite. The aim of the study was to determine how the integration period of the bone substitute material, that is, 3 months or 6 months, influences implant integration within the patient's upper jaw. Therefore, the following clinical and radiologic parameters were investigated: implant being in situ; Periotest value; and presence of peri-implant osteolysis, bleeding on probing, plaque, and soft tissue recession around the …

AdultMalemedicine.medical_specialtySinus Floor AugmentationTime FactorsDental PlaqueSinus Floor AugmentationDentistryOsteolysisOsseointegrationDental Prosthesis RetentionOsseointegrationMaxillamedicineHumansGingival RecessionDental Restoration FailureSinus (anatomy)AgedDental Implantsbusiness.industryMiddle AgedSurvival AnalysisSurgeryRadiographyDurapatitemedicine.anatomical_structureBone SubstitutesNanoparticlesFemaleImplantPeriodontal IndexOral SurgerybusinessFollow-Up StudiesJournal of Oral Implantology
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A randomised clinical trial to evaluate the acceptability and efficacy of an early phase, online, guided augmentation of outpatient care for adults w…

2019

AbstractBackgroundOutpatient interventions for adult anorexia nervosa typically have a modest impact on weight and eating disorder symptomatology. This study examined whether adding a brief online intervention focused on enhancing motivation to change and the development of a recovery identity (RecoveryMANTRA) would improve outcomes in adults with anorexia nervosa.MethodsParticipants with anorexia nervosa (n= 187) were recruited from 22 eating disorder outpatient services throughout the UK. They were randomised to receiving RecoveryMANTRA in addition to treatment as usual (TAU) (n= 99; experimental group) or TAU only (n= 88; control group). Outcomes were measured at end-of-intervention (6 w…

AdultMalemedicine.medical_specialtySocial adjustmentAdolescentPsychological interventionAnorexia nervosa; augmentation; early symptom change; feasibility; guidance; motivation; online; recovery; self-help; trialAnxietyBody Mass IndexYoung AdultrecoveryAmbulatory caremotivationSettore M-PSI/08 - Psicologia ClinicaaugmentationmedicineHumansAnorexia nervosa augmentation early symptom change feasibility guidance motivation online recovery self-help trialearly symptom changeself-helpApplied PsychologyonlineInternetbusiness.industryAnorexia nervosatrialClinical trialSelf CarePsychiatry and Mental healthAnorexia nervosa (differential diagnoses)Physical therapyAnxietyFemalemedicine.symptomEarly phasebusinessBody mass indexguidancefeasibility
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A new morphologic classification of the alveolar ridge after distraction osteogenesis in human patients. A 17 years retrospective case series study

2020

Background To perform a morphologic classification based on the results of bone augmentation after a distraction osteogenesis. Material and Methods Thirty-four (34) patients (24 women and 10 men; mean age, 47.1 years (SD=9.5); age range, 23 to 62 years) underwent a total of 42 alveolar ridge distractions before the placement of a total of 89 dental implants. Ridge bone morphology was evaluated as the main ordinal variable. Chi-squared, Kruskal-Wallis and ANOVA one-way test were used. Results Category I (30.95%): consisted of wide alveolar rim and no bone defects Category II (28.57%): wide alveolar rim, lateral bone surface concavity. Category III (23.81%): narrow alveolar rim, lateral bone …

AdultMalemedicine.medical_treatmentOsteogenesis DistractionBone augmentationYoung AdultpreventionDistractionAlveolar ridgeAlveolar ProcessMedicineHumansclinical protocolsmedication-related osteonecrosis of the jawBone regenerationGeneral DentistryUNESCO:CIENCIAS MÉDICASRetrospective StudiesSubcategoryOrthodonticsDental Implantsbusiness.industryResearchDental Implantation EndosseousAlveolar Ridge AugmentationMiddle AgedBridge (graph theory)Otorhinolaryngologyclinical guidelinesDistraction osteogenesisSurgeryFemaleOral SurgerybusinessCase series
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Complications of Poly Implant Prothèse breast implants: the current discussion

2013

Against the background of the current discussion about Poly Implant Prothèse (PIP, Seyne-sur-mer, France) breast implants, we want to present a case demonstrating the complications such as implant rupture, silicone dissemination and level III silicone lymphadenopathy. A 29-year-old woman with cosmetic breast augmentation with PIP implants 5 years previously showed a sensitive swelling in her right axilla and neck region. All tests to detect an infectious or lymphomatous lymphadenopathy were negative. After ultrasound and MRI, rupture of the right implant was assumed and multiple pathologically enlarged lymph nodes up to supraclavicular region were shown. An excision biopsy of one axillary l…

AdultReoperationmedicine.medical_specialtyAxillary lymph nodesBiopsyBreast ImplantsBiomedical EngineeringProsthesis DesignSilicone Gelschemistry.chemical_compoundSiliconeBiopsymedicineHumansBreast ImplantationLymphatic DiseasesBreast augmentationLymph nodeDevice Removalmedicine.diagnostic_testbusiness.industryForeign-Body ReactionGeneral MedicineProsthesis FailureSurgeryAxillaTreatment Outcomemedicine.anatomical_structurechemistryAxillaLymph Node ExcisionFemaleSurgeryLymph NodesLymphImplantbusinessExpert Review of Medical Devices
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Stressor-related impairment of synaptic transmission in hippocampal slices from α-synuclein knockout mice

2004

The role of alpha-synuclein (alpha-Syn) has recently received considerable attention because it seems to play a role in Parkinson's disease (PD). Missense mutations in the alpha-Syn gene were found in autosomal dominant PD and alpha-Syn was shown to be a major constituent of protein aggregates in sporadic PD and other synucleinopathies. Under normal conditions, alpha-Syn protein is found exclusively in synaptic terminals. However, the potential participation of alpha-synuclein in maintaining and regulating synaptic efficacy is unknown. We have investigated the excitatory synaptic modulation of alpha-synuclein in CA1 pyramidal neurons, using the in vitro hippocampal slice technique. The 4-am…

Alpha-synucleinanimal diseasesGeneral NeuroscienceHippocampusNeurotransmissionBiologynervous system diseaseschemistry.chemical_compoundSynaptic fatiguenervous systemchemistrySynaptic augmentationSynaptic plasticityKnockout mouseExcitatory postsynaptic potentialNeuroscienceEuropean Journal of Neuroscience
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Minireview: pH and synaptic transmission

2013

AbstractAs a general rule a rise in pH increases neuronal activity, whereas it is dampened by a fall of pH. Neuronal activity per se also challenges pH homeostasis by the increase of metabolic acid equivalents. Moreover, the negative membrane potential of neurons promotes the intracellular accumulation of protons. Synaptic key players such as glutamate receptors or voltage-gated calcium channels show strong pH dependence and effects of pH gradients on synaptic processes are well known. However, the processes and mechanisms that allow controlling the pH in synaptic structures and how these mechanisms contribute to normal synaptic function are only beginning to be resolved.

BiophysicsNeurotransmissionBiochemistryMouse modelGABAStructural BiologySynaptic augmentationGeneticsAnimalsHumansPremovement neuronal activitySynaptic transmissionMolecular BiologyNeuronal excitabilityCarbonic AnhydrasesAcid-Base EquilibriumMembrane potentialCarbonic anhydraseVoltage-dependent calcium channelChemistryGlutamate receptorCell BiologyBicarbonatesSynaptic fatigueBiochemistrypH regulationSynapsesSynaptic plasticityBiophysicsIon transporterFEBS Letters
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