Search results for " bioengineering"
showing 10 items of 119 documents
Design and development of hyaluronan-functionalized polybenzofulvene nanoparticles as CD44 receptor mediated drug delivery system
2017
A tri-component polymer brush (TCPB), composed of a polybenzofulvene copolymer bearing low molecular weight hyaluronic acid (HA) on the surface of its cylindrical brush-like backbone and oligo-PEG fractions, was employed in the preparation of 350Â nm nanostructured drug delivery systems capable of delivering the anticancer drug doxorubicin. The obtained drug delivery systems were characterized on the basis of drug loading and release, dimensions and zeta potential, morphology and in vitro cell activity, and uptake on three different human cell lines, namely the bronchial epithelial 16HBE, the breast adenocarcinoma MCF-7, and the colon cancer HCT116 cells. Finally, the ability of doxorubicin…
Microleakage in Class II composite restorations with margins below the CEJ: in vitro evaluation of different restorative techniques.
2012
Objectives: The purpose of this in vitro study was to evaluate the microleakage in "deep" Class II composite restorations with gingival cavosurface margin below the CEJ (cemento-enamel junction) and restored with different techniques. Study Design: Fifty human teeth were used. In each tooth two standardized Class II slot cavities (on mesial and on distal surfaces) were prepared: the buccolingual extension of the cavities was 4 mm; the gingival wall was located in dentin/cementum (2 mm beyond the CEJ). The prepared teeth were randomly assigned to 5 experimental groups (of 10 specimens and 20 cavities each) and restored. Group 1: Filtek TM Supreme XTE Flowable (3MESPE) + Universal Filtek Supr…
Testing mechanical characteristics of chestnut stakes used in bed sills for stream restoration
2017
Using of wood elements for constructing bed sills in Mediterranean streams, where the banks are not protected by tree vegetation, needs an evaluation of biological and mechanical characteristics for evaluating both the wood durability and the effectiveness of the stream restoration project. Very few studies have dealt both with the decay of mechanical characteristics of wood elements employed for stream restoration works and with the changes over time of physical and chemical wood characters. In this paper, for a wood and stone bed sill located in a stream having no shaded banks, the changes of physical and chemical characters detected after 12, 18, 24, 30, 36, 42 and 48 months on chestnut …
Building green covering for a sustainable use of energy
2013
Nowadays the growth of the cities increased built and paved areas, energy use and heat generation. The phenomenon of urban warming, called urban heat island, influences negatively outdoor comfort conditions, pollutants concentration, energy demand for air conditioning, as well as increases environmental impact due to the demand of energy generation. A sustainable technology for improving the energy efficiency of buildings is the use of green roofs and walls in order to reduce the energy consumption for conditioning in summer and improve the thermal insulation in winter. The use of green roofs and walls can contribute to mitigate the phenomenon of heat island, the emissions of greenhouse gas…
Greenhouse gas emissions and the links to plant performance in a fixed-film activated sludge membrane bioreactor - Pilot plant experimental evidence
2017
The present study explores the interlinkages among the operational variables of a University of Cape Town (UCT) Integrated Fixed Film Activated Sludge (IFAS) membrane bioreactor (MBR) pilot plant. Specifically, dedicated experimental tests were carried out with the final aim to find-out a constitutive relationship among operational costs (OCs), effluent quality index (EQI), effluent fines (EF). Greenhouse gas (GHG) emissions were also included in the study. Results showed that the EQI increases at low flow rate likely due to the dissolved oxygen (DO) limitation in the biological processes. Direct GHGs increase with the increasing of the air flow due to the anoxic N2O contribution. Irreversi…
Free surface oxygen transfer in large aspect ratio unbaffled bio-reactors, with or without draft-tube
2015
Abstract It is widely accepted that animal cell damage in aerated bioreactors is mainly related to the bursting of bubbles at the air–liquid interface. A viable alternative to sparged bioreactors may be represented by uncovered unbaffled stirred tanks, which have been recently found to be able to provide sufficient mass transfer through the deep free surface vortex which takes place under agitation conditions. As a matter of fact, if the vortex is not allowed to reach impeller blades, no bubble formation and subsequent bursting at the free-surface, along with relevant cells damage, occurs. In this work oxygen transfer performance of large aspect ratio unbaffled stirred bioreactors, either e…
Greenhouse gases from sequential batch membrane bioreactors: A pilot plant case study
2016
Abstract The paper reports the results of nitrous oxide (N 2 O) emissions from aerobic and anoxic tank of a Sequential Batch Membrane Bioreactor (SB-MBR) pilot plant. The influence of salinity variation on N 2 O emission was analyzed by gradually increasing the inlet salt concentration from 0 to 10 g NaCl L −1 . The observed results showed that the N 2 O concentration of the gaseous samples was strongly influenced by the salt concentration. This result was likely related to a worsening of the nitrification activity due to the effect of salinity on autotrophic bacteria. Dissolved oxygen concentration and salinity were found to be the key factors affecting N 2 O concentration in the gaseous s…
Moving bed membrane bioreactors for carbon and nutrient removal: The effect of C/N variation
2017
In this paper, an experimental campaign was carried out on a University of Cape Town Integrated Fixed Film Activated Sludge Membrane Bioreactor (UCT-IFAS-MBR) pilot plant. The aim of the study was to evaluate the effect of the influent C/N ratio on the system performance in terms of organic carbon, nitrogen and phosphorus removal, biomass viability (through respirometry), activated sludge features and membrane filtration properties. The experiments were organized into three phases, characterized by a variation of the C/N ratio (namely, Phase I: C/N= 5, Phase II: C/N =10; Phase III: C/N = 2). The results highlighted that the system performance was significantly affected by C/N ratio. The rem…
Greenhouse gases from membrane bioreactors: Mathematical modelling, sensitivity and uncertainty analysis
2017
In this study a new mathematical model to quantify greenhouse gas emissions (namely, carbon dioxide and nitrous oxide) from membrane bioreactors (MBRs) is presented. The model has been adopted to predict the key processes of a pilot plant with pre-denitrification MBR scheme, filled with domestic and saline wastewater. The model was calibrated by adopting an advanced protocol based on an extensive dataset. In terms of nitrous oxide, the results show that an important role is played by the half saturation coefficients related to nitrogen removal processes and the model factors affecting the oxygen transfer rate in the aerobic and MBR tanks. Uncertainty analysis showed that for the gaseous mod…
The role of EPS in the foaming and fouling for a MBR operated in intermittent aeration conditions
2016
Abstract This work investigates the causes of foaming and fouling in an Intermittent Aerated – Membrane BioReactor (IA-MBR) used for wastewater treatment. The experiment was divided into three periods with different aerated regimes expressed with different t aeration /t cycle ratio (Period I: 60 min/180 min, Period II: 80 min/180 min, Period III: 30 min/90 min). The advanced foaming tests used allow the study of the role of extracellular polymeric substances (EPSs) on foaming and fouling. In general, in the Periods I and II, good correlations between the EPSs and the Modified Scum Index without purification (MSI 0 ) and the Foam Power were observed. The results shown that the filamentous mi…