Search results for " bone"

showing 10 items of 933 documents

Histological characteristics of the vertebral intercentra of Metoposaurus diagnosticus (Temnospondyli) from the Upper Triassic of Krasiejów (Upper Si…

2012

ABSTRACTOsteohistological characteristics of the large temnospondyl amphibian Metoposaurus diagnosticus from the Upper Triassic of Poland (Krasiejów locality) were determined using vertebral intercentra thin-sections from different regions and growth stages. The intercentra showed a trabecular structure in both the endochondral and periosteal domains. Endochondral ossification developed first, and the primary bone occurs near the periphery with a higher degree of remodelling in the centre. Periosteal bone deposition begins later; first on the ventral side, continuing laterally and finally onto the dorsal side. Periosteal growth rate was initially very rapid, and then subsequently decreased …

biologyCartilageVentral sideHOSTemnospondylimorphogenesisAnatomyMetoposaurusbiology.organism_classificationCalcified cartilagePrimary bonemedicine.anatomical_structuremedicineGeneral Earth and Planetary SciencescartilagepaedomorphosisNeotenyEndochondral ossificationGeologypalaeohistologyGeneral Environmental ScienceEarth and Environmental Science Transactions of the Royal Society of Edinburgh
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Long bone histology of Metoposaurus diagnosticus (Temnospondyli) from the Late Triassic of Krasiejów (Poland) and its paleobiological implications

2013

ABSTRACT Long bones of the temnospondyl Metoposaurus diagnosticus krasiejowensis from the Late Triassic of Krasiejow, Poland, were studied using histological analysis. Six femora, three humeri, a radius, and an ulna were prepared for thin-sectioning. In all bones, the dominant type of primary bone matrix is parallel-fibered bone with secondary, or rarely primary, deposition of lamellar bone inside vascular canals. Two small humeri and the smallest femur showed incipient fibrolamellar bone, which may be a character typical for juvenile individuals. The medullary region is filled with well-developed trabecular bone. The growth marks in all bones are organized as thick layers of highly vascula…

biologyMedullary cavityUlnaLong bonePaleontologyTemnospondyliHistologyAnatomyMetoposaurusbiology.organism_classificationPaleontologymedicine.anatomical_structurePrimary bonemedicineFemurGeologyJournal of Vertebrate Paleontology
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Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020

2020

The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of patients, but also on the decision-making process by the majority of dentists and oral surgeons involved in MRONJ prevention (primary and secondary). The present paper reports the update of the conclusions from the Consensus Conference—held at the Symposium of the Italian Society of Oral Pathology and Medicine (SIPMO) (20 October 2018, Ancona, Italy)—after the newest recommendations (2020) on MRONJ were published by two scientific societies (Italian Societies of Maxillofacial Surgery and Oral Pathology and Medicine, SI…

bisphosphonateOral SurgeonHealth Toxicology and Mutagenesislcsh:MedicineMRONJantiangiogenic agents; antiresorptive drugs; bisphosphonates; cancer; denosumab; dentistry; MRONJ; oral surgery; osteoporosis; prevention models; bisphosphonate-associated osteonecrosis of the jaw; bone density conservation agents; diphosphonates; humans; Italy; quality of life0302 clinical medicineprevention modelCancerantiangiogenic agentsdentistryBone Density Conservation AgentsDiphosphonatesConference ReportBisphosphonatesAntiresorptive DrugsDenosumabItaly030220 oncology & carcinogenesisBisphosphonate-Associated Osteonecrosis of the JawDenosumabmedicine.drugoral surgerymedicine.medical_specialtyOral surgery03 medical and health sciencesOral surgeryAntiangiogenic agentsOral and maxillofacial pathologymedicinecancerHumansantiangiogenic agentantiresorptive drugsIntensive care medicinePrevention modelsbisphosphonatesantiresorptive drugAntiangiogenic agentsbusiness.industrylcsh:RPublic Health Environmental and Occupational Healthdenosumab030206 dentistrymedicine.diseaseosteoporosisAntiresorptive drugsDentistryOsteoporosisprevention modelsbusinessAntiangiogenic agents; Antiresorptive drugs; Bisphosphonates; Cancer; Denosumab; Dentistry; MRONJ; Oral surgery; Osteoporosis; Prevention models
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OPTIMIZING PREIMPLANTARY OFFER TROUGH PIEZOSURGERY TECHNIQUES

2016

Introduction. In most of the cases, duet o post-extractional atrophy the bone offer is insufficent for placing implants. Piezosurgery splitting techniques represent the modern and non-invasive alternative used for ridge remodeling, sinus lift and other surgical bone preservation maneuvres. Purpose. The purpose of this study is to present new surgical techniques that radically simplify maxillary sinus interventation, avoiding membrane perforation and new splitting tecniques in advanced bone and ridge atrophy. Material and method. In this study, sinus lifting was performed using piezo-elevation of the membrane and the pressure ogenerated by the saline solution. Out of 67 patients, 20 have had…

bone augmentationlcsh:RK1-715lcsh:Dentistrypiezosurgery techniquesinitial bone offerRomanian Journal of Oral Rehabilitation
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Systemic risk factors for peri-implant bone loss: a systematic review and meta-analysis

2014

The aim of this study was to determine the influence of patient-related systemic risk factors (systemic disease, genetic traits, chronic drug or alcohol consumption, and smoking status) on peri-implant bone loss at least 1 year after implant installation and prosthetic loading. An electronic search was performed of MEDLINE, EMBASE, and The Cochrane Central Register of Controlled Trials up to January 2012. One thousand seven hundred and sixty-three studies were identified. After applying a three-stage screening process, 17 articles were included in the qualitative analysis, but only 13 in the quantitative analysis, since smoking was a common exposure. The meta-analysis of these 13 studies (4…

bone loss; risk factors; meta-analysis; systemic diseases; smoking; dental implantsSystemic diseasemedicine.medical_specialtyGenetic traitsAlveolar Bone LossMEDLINEDentistryPeri implant bonesmokingbone lossRisk FactorsInternal medicinemedicineSystemic riskHumansIMPLANTES DENTÁRIOSDental Restoration FailureDental Implantsbusiness.industryDental Implantation EndosseousEvidence-based medicinemedicine.diseasemeta-analysissystemic diseasesOtorhinolaryngologyMeta-analysisSurgeryImplantOral Surgerybusiness
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Gigantic peripheral osteoma of the mandible: a case report

2010

Osteomas are osteogenic lesions that have a limited growth potential. They are comprised of histologically and radiographically normal bone. Osteomas are categorized as central, peripheral or extraskeletal according to location. Clinically, peripheral osteomas (PO) are unilateral, sessile or pedunculated and have mushroom-like lesions ranging from 10 to 40 mm in diameter. Osteomas affecting the mandible are rare. In this report, we presented a gigantic peripheral mass on the left mandible in a 55-year old patient exhibiting clinical signs related to neoplasia.

business.industryMandibleOdontologíaAnatomymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludPeripheralbody regionsNormal boneUNESCO::CIENCIAS MÉDICASMedicinebusinessGeneral DentistryOsteoma
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Progressive femoral cortical and cancellous bone density loss after uncemented tapered-design stem fixation

2010

Background Aseptic implant loosening and periprosthetic bone loss are major problems after total hip arthroplasty (THA). We present an in vivo method of computed tomography (CT) assisted osteodensitometry after THA that differentiates between cortical and cancellous bone density (BD) and area around the femoral component.Method Cortical and cancellous periprosthetic femoral BD (mg CaHA/mL), area (mm2) and contact area between the prothesis and cortical bone were determined prospectively in 31 patients 10 days, 1 year, and 6 years after uncemented THA (mean age at implantation: 55 years) using CT-osteodensitometry.Results 6 years postoperatively, cancellous BD had decreased by as much as 41%…

business.industryPeriprostheticGeneral MedicineAnatomymedicine.diseaseOsteopeniaDiaphysismedicine.anatomical_structuremedicineOrthopedics and Sports MedicineSurgeryCortical boneFemurImplantbusinessCancellous boneFixation (histology)Acta Orthopaedica
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Influence of Different Rehydration Protocols on Biomechanical Properties of Allogeneic Cortical Bone Plates: A Combined in-vitro/in-vivo Study

2020

Introduction: Allogeneic cortical bone plates (CP) are used for alveolar ridge augmentation. Since CP are freeze-dried and dehydrated during processing, the breaking strength (BS) and the flexibility (FX) are reduced, resulting in a relevant risk for plate fractures during insertion. The aim of this study was to evaluate the influence of rehydration time on the biomechanical properties (BS & FX) of CP in-vitro and in vivo.Material and Methods: 40 CP were randomly divided into four experimental groups. (A) untreated control (n = 10), rehydration for 10 (B), 30 (C) and 60 (D) minutes in 0.9% saline solution (n = 10 each). BS [Newton, N] and FX [mm] (force till fracture and distance of deflect…

business.industrymedicine.medical_treatmentBreaking pointBreaking strength03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureUntreated control030220 oncology & carcinogenesismedicine030211 gastroenterology & hepatologySurgeryIn patientCortical boneIn vitro in vivobusinessSalineBiomedical engineeringJournal of Investigative Surgery
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Radiological assessment of peri-implant bone loss: a 12-month retrospective study

2011

Introduction: Following dental implant loading, marginal bone loss after one year must be evaluated to check correct maintenance of the bone levels. Objectives: To assess implant treatment success and quantify marginal bone loss 6 and 12 months after loading. Material and method: Sixty-one MIS® implants with a 1.8 mm machined neck were placed in 26 patients. Implant success was based on the criteria of Buser. Radiological controls were made 6 and 12 months after loading, measuring bone loss mesial and distal. Results: Twenty-two patients with 56 implants were included: 32 in the maxilla and 24 in the mandible. Two implants failed in two patients during the osseointegration phase (both in th…

business.industrymedicine.medical_treatmentMandibleDentistryRetrospective cohort studyOdontologíaPeri implant bone:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOsseointegrationMaxillaRadiological weaponUNESCO::CIENCIAS MÉDICASmedicineImplantDental implantbusinessGeneral Dentistry
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MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells

2014

Osteosarcoma (OS) is the most common type of bone cancer, with a peak incidence in the early childhood. Emerging evidence suggests that treatments targeting cancer stem cells (CSCs) within a tumor can halt cancer and improve patient survival. MicroRNAs (miRNAs) have been implicated in the maintenance of the CSC phenotype, thus, identification of CSC-related miRNAs would provide information for a better understanding of CSCs. Downregulation of miRNA-29 family members (miR-29a/b/c; miR‑29s) was observed in human OS, however, little is known about the functions of miR-29s in human OS CSCs. Previously, during the characterization of 3AB-OS cells, a CSC line selected from human OS MG63 cells, we…

cancer stem cellsHomeobox protein NANOGCancer Research3AB-OS cells; Cancer stem cells; MicroRNA; MicroRNA-29b-1; Multidrug resistance; Osteosarcoma; Bone Neoplasms; Cell Line Tumor; Cell Movement; Cell Proliferation; Drug Resistance Neoplasm; Gene Expression Regulation Neoplastic; Humans; MicroRNAs; Neoplasm Invasiveness; Osteosarcoma; Cancer Research; OncologyDrug ResistanceBone NeoplasmsBiologyCell LineSOX2multidrug resistanceCell MovementCancer stem cellCell Line TumorSettore BIO/10 - BiochimicamicroRNAmedicineHumansNeoplasm InvasivenessClonogenic assaymicroRNA-29b-1Cell ProliferationNeoplasticOsteosarcomaTumormicroRNAOncogeneCancer3AB-OS cellsArticlesCell cyclemedicine.diseaseGene Expression Regulation Neoplasticosteosarcoma cancer stem cells microRNA microRNA-29b-1 multidrug resistance 3AB-OS cellsMicroRNAsGene Expression RegulationOncologyDrug Resistance NeoplasmImmunologyCancer researchNeoplasm
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