Search results for " brain"
showing 10 items of 985 documents
POLYMERIC MICELLES AS DRUG DELIVERY SYSTEMS TOWARDS BRAIN TARGETING
2009
Brainstem hyperactivity in migraine
2000
La mente del bambino: tra lungimiranza pedagogica ed evidenze neuroscientifiche. Uno studio comparato su Maria Montessori e la Brain-based Education
2021
Il paper intende tracciare una linea di congiunzione tra le intuizioni di Maria Montessori e le recenti evidenze neuroscientifiche: “La scoperta del bambino”, auspicata dalla studiosa all’inizio del XX secolo, è tuttora in corso e punta alla conquista della comprensione del funzionamento della mente del bambino. In particolare, la riflessione si sviluppa attorno ai seguenti temi: neuroplasticità neuronale e sinaptogenesi, lo sviluppo motorio, il processo attentivo e il meccanismo della mimesi. Questi argomenti, rinvigoriti dal dialogo tra la pedagogia montessoriana e le ricerche neuroscientifiche, possono determinare un nuovo modo di intendere la questione e la prassi educativa. The paper i…
Exosomal HSP60 levels and related miRNAs in brain tumors
In cancer, Extracellular Vesicles (EVs), such as exosomes, contribute to tumor progression by regulating local and systemic parameters. Since exosomes are released into body fluids, they may be used in nanomedicine as a valuable source of diagnostic biomarkers. The prognosis of brain tumors is poor even after surgical resection followed by post-operatory chemo- and radio-therapies and it is cogent to find innovative treatments. The discovery that molecular chaperones can be determinant factors in tumorigenesis and the increasing understanding of exosomes, particularly in what refers to their release by tumor cells and contents, including chaperones and miRNA, provide elements to develop nov…
Transcranial direct current stimulation for treatment of freezing of gait: a cross-over study.
2014
BACKGROUND AND OBJECTIVE: Progression of Parkinson's disease (PD) is frequently characterized by the occurrence of freezing of gait (FOG) representing a disabling motor complication. We aim to investigate safety and efficacy of transcranial direct current stimulation of the primary motor cortex of PD patients with FOG. METHODS: In this cross-over, double-blind, sham-controlled study, 10 PD patients with FOG persisting in "on" state underwent anodal and sham direct current stimulation for 5 consecutive days. Clinical assessment over a 1-month period was performed. RESULTS: A significant improvement of gait, as assessed by the Stand Walk Sit test, with reduction in number and duration of FOG …
Lo sviluppo dell’intelligenza linguistica e della competenza comunicativa degli studenti universitari. Un esperimento Brain-Based in Dad
2021
Il contributo presenta l’utilizzo di un approccio di tipo Brainbased allo sviluppo dell’intelligenza linguistica e della correlata competenza linguistico-comunicativa, che ha permesso la sperimentazione di una batteria di attività di Brain Gym (Dennison & Dennison, 2008) nel contesto didattico universitario durante il periodo di Didattica a Distanza (DAD) imposta dalla pandemia da Covid-19. La DAD ha comportato una drastica limitazione di alcuni elementi considerati fondanti per lo sviluppo delle competenze linguistiche, espressive e comunicative quali la corporeità, il controllo visuo-acustico, i tempi d’attenzione, la gestualità, il contatto. Nella sua fase iniziale, la ricerca condot…
Lymphatic vessels of the dura mater: a new discovery?
2015
Aspelund et al. discover the presence of a lymphatic vessel network in the dura mater of the mouse brain and show that these dural lymphatic vessels are important for the clearance of macromolecules from the brain.
Chapter 31 Transcranial magnetic stimulation studies of contralesional space attention deficits
2002
Publisher Summary The power of transcranial magnetic stimulation (TMS) to disrupt and modulate the neural activity in focal brain regions has provided researchers in this field a promising tool to empirically test specific neuropsychological models and constructs of contralesional space attention deficits. A group of studies has used TMS to transiently disrupt the cortical activity of the focal brain areas in normal subjects to replicate the effects of neurological lesions. This chapter discusses a number of studies, using single-pulse, paired-TMS, and repetitive TMS (rTMS) and different experimental paradigms that show how this technique can be of fundamental importance, in elucidating the…
La ciència com a cerca. Don Quixot, la neurociència i l'interrogatori de la veritat
2014
El neurocientifi c Rodrigo Quian Quiroga es va preguntar si «els cientifi cs, embarcats en cerques personals i quixotesques croades, es passen el temps pensant». Aquesta invocacio adjectival del Quixot de Cervantes presenta la ciencia com una cerca epica que equipara la racionalitat cientifi ca amb els deliris de Don Quixot. Es la cerca de la veritat per part de la ciencia, quixotesca i literaria, un «racionalisme neurotic», en paraules del fi losof Nicholas Maxwell?