Search results for " breast cancer"
showing 10 items of 427 documents
From molecular analysis to histopathology: alpha-enolase/MBP1 isoforms expression in breast cancer
2008
Identification of a prognostic gene signature associated with MBP-1 expression in ErbB2-negative breast carcinomas
2014
The ENO1 transcript, which encodes the glycolitic enzyme alpha-enolase, can be translated into a shorter nuclear protein called Myc-promoter Binding Protein-1 (MBP-1) by using an alternative translation start site. MBP-1 acts as a negative regulator of c-Myc, ErbB2 and Cox2 genes (1). Several evidences indicate that MBP-1 acts as a tumor suppressor in breast carcinoma and prostate cancer and its expression results in a reduced invasive ability (2). In our previous studies, we showed that MBP-1 is expressed and easily detectable in normal breast epithelial cells, but a loss of expression occurs in most primary invasive ductal carcinomas (IDC) of the breast. Furthermore, in these tumors MBP-1…
Anti-oncogenic role of decorin: identification of new markers.
2009
The fibroblasts: co-actors in cancer.
2008
Cytotoxic effect of the HDAC3 inhibitor Pojamide and its variants on MDA-MB231 breast cancer cells
2018
Statistical validation of a comprehensive gene/miRNA expression profile dataset for miRNA:mRNA interctome analysis
2014
EFFECTS OF CELLULAR SHORT-TERM STARVATION ON CONVENTIONAL CHEMOTHERAPY RESPONSE IN HUMAN CANCER: UNDERSTANDING OF MOLECULAR MECHANISMS AND MICRORNAS …
Background: Short Term Starvation (STS) is a type of dietary restriction able to reduce tumorigenesis and cancer progression but molecular bases of this effect are still unclear. Aim: In vitro analysis of STS effects in presence of chemotherapy and evaluation of microRNAs (miRNAs) involvement. Results: STS affects the expression profiles of miRNAs involved in chemotherapy response leading to cancer cells sensitization and to healthy cells protection.