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showing 10 items of 871 documents
A proof of bistability for the dual futile cycle
2014
Abstract The multiple futile cycle is an important building block in networks of chemical reactions arising in molecular biology. A typical process which it describes is the addition of n phosphate groups to a protein. It can be modelled by a system of ordinary differential equations depending on parameters. The special case n = 2 is called the dual futile cycle. The main result of this paper is a proof that there are parameter values for which the system of ODE describing the dual futile cycle has two distinct stable stationary solutions. The proof is based on bifurcation theory and geometric singular perturbation theory. An important entity built of three coupled multiple futile cycles is…
Kwalifikacja pisma procesowego jako apelacji lub wniosku o doręczenie wyroku z uzasadnieniem. Glosa do uchwały Sądu Najwyższego - Izba Pracy i Ubezpi…
2022
The commented resolution of the Supreme Court concerns the classification of a pleading filed by an insured person, the content of which indicates that the person disagrees with a decision on the merits of the case, in the context of doubts as to whether the pleading constitutes an appeal or a request for the service of a judgment with a statement of reasons. The Supreme Court held that if this type of uncertainty arises, the court should take action to clarify the real intention of the party, i.e. summon the insured person, on pain of returning the pleading, to remedy the formal defect of failing to identify the type of pleading. This view has been justified with good arguments, in particu…
La prestación de maternidad en los supuestos de gestación subrogada
2018
Surrogate pregnancy, as a technique of assisted reproduction prohibited by Spanish law, raises a number of legal questions than, in certain cases, trascend of the Civil Law. Specifically, it has been discussed about de possibility that de person or persons consigner in the gestation contract substitution have access to the provision for maternity benefit. Recently, the Spanish Supreme Court has responded to this issue in the sense of recognizing the right to the provision for maternity benefit to the father or mother ?in fact?, efecttively, develop own parental powers.
Stakeholder theory for the E -government context: Framing a value-oriented normative core
2018
Despite substantial investments in ICT in the public sector over the past decades, it has been hard to achieve consistent benefits. One reason for the difficulties is the gap between the expectations of key stakeholders (such as governments, businesses and citizens) and project outcomes. Though normative, descriptive and instrumental aspects of stakeholder theory have been influential in explaining stakeholder interests and relationships in the management field, e-Government researchers have rather neglected the normative core of the theory. We show how value theory can improve normative foundations in this area to provide a focused analysis of four e-Government projects. We use a multiple …
The Micro and Meso Levels of Activism: A Comparative Case Study of Attac France and Attac Germany
2014
The embodied sources of purpose expressions in Latin
2016
This chapter examines the phrasal means of encoding the semantic role of purpose in Latin. After discussing the notion of semantic role and its use in cognitive linguistics, we illustrate the conceptual relation between the notional domains of space and causation. On this basis, we analyze the source of purpose expressions in Latin, which are mainly based on direction (bare dative and the allative markers, i.e. ad / in + accusative), but also include prepositional phrases metaphorically derived from location (e.g. per + accusative, prō + ablative, propter + accusative), or metonymically spreading from reason to purpose (as in the case of causal markers such as genitive + causā and gratiā ).
Zur numerischen Lösung gewöhnlicher Differential-gleichungen mit Splines in einem Sonderfall
1980
In an earlier paper [1] a general procedure has been presented to obtain polynomial spline approximations for the solution of the initial value problem for ordinary differential equations. In this paper the general procedure is described by an equivalent one step method. Furthermore two convergence theorems are proved for a special case which is not included in the general convergence or divergence theory given in [1].
A dynamic business modelling approach to design and experiment new business venture strategies
2018
Abstract Business Modelling has evolved as a key activity to reflect new business venture strategy by framing the way a firm will operate and how it will function in achieving its goals (e.g., profitability, growth, innovation, social impact). However, scholars and practitioners have criticized the adoption of a too static perspective in the design and use of conventional Business Model representations. Such a static perspective prevents nascent entrepreneurs experimenting with their Business Models and, as a result, identifying the most effective strategies, especially in terms of business sustainability and profitability. In this paper, we argue that combining conventional Business Model …
Cotas inferiores para el QAP-Arbol
1985
The Tree-QAP is a special case of the Quadratic Assignment Problem where the flows not equal zero form a tree. No condition is required for the distance matrix. In this paper we present an integer programming formulation for the Tree-QAP. We use this formulation to construct four Lagrangean relaxations that produce several lower bounds for this problem. To solve one of the relaxed problems we present a Dynamic Programming algorithm which is a generalization of the algorithm of this type that gives a lower bound for the Travelling Salesman Problem. A comparison is given between the lower bounds obtained by each ralaxation for examples with size from 12 to 25.
The Raising Factor, That Great Unknown. A Guided Activity for Undergraduate Students
2020
In the first years of their economics degree programs, students will face many problems successfully dealing with a range of subjects with quantitative content. Specifically, in the field of statistics, difficulties to reach some basic academic achievements have been observed. Hence, a continuing challenge for statistics teachers is how to make this subject more appealing for students through the design and implementation of new teaching methodologies. The latter tend to follow two main approaches. On the one hand, it is useful for the learning process to propose practical activities that can connect theoretical concepts with real applications in the economic context. On the other hand, we …