Search results for " childhood"

showing 10 items of 507 documents

Neurodegenerative changes are prevented by Erythropoietin in the pmn model of motoneuron degeneration

2014

Motoneuron diseases are fatal neurodegenerative disorders characterized by a progressive loss of motoneurons, muscle weakness and premature death. The progressive motor neuronopathy (pmn) mutant mouse has been considered a good model for the autosomal recessive childhood form of spinal muscular atrophy (SMA). Here, we investigated the therapeutic potential of Erythropoietin (Epo) on this mutant mouse. Symptomatic or pre-symptomatic treatment with Epo significantly prolongs lifespan by 84.6% or 87.2% respectively. Epo preserves muscle strength and significantly attenuates behavioural motor deficits of mutant pmn mice. Histological and metabolic changes in the spinal cord evaluated by immunoh…

medicine.medical_specialtyMutantMotor ActivitySpinal Muscular Atrophies of ChildhoodMiceCellular and Molecular NeuroscienceWestern blotInternal medicineReceptors ErythropoietinmedicineAnimalsErythropoietinMotor NeuronsPharmacologymedicine.diagnostic_testbusiness.industryMuscle weaknessSpinal muscular atrophymedicine.diseaseSpinal cordSMA*Mice Mutant StrainsDisease Models Animalmedicine.anatomical_structureEndocrinologySpinal CordErythropoietinImmunohistochemistrymedicine.symptombusinessNeurosciencemedicine.drugNeuropharmacology
researchProduct

Maternal personality profile of children affected by migraine

2013

Maria Esposito,1 Michele Roccella,2 Beatrice Gallai,3 Lucia Parisi,2 Serena Marianna Lavano,4 Rosa Marotta,4 Marco Carotenuto1 1Center for Childhood Headache, Second University of Naples, Naples, Italy; 2Department of Psychology, University of Palermo, Palermo, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 4Department of Psychiatry, Magna Graecia University of Catanzaro, Catanzaro, Italy Background: Empirical evidence of the important role of the family in primary pediatric headache has grown significantly in the last few years, although the interconnections between the dysfunctional process and the family interaction are still unclear. Even th…

medicine.medical_specialtyNeuropsychiatric Disease and Treatmentmedia_common.quotation_subjectDysfunctional familychildhood migrainePsychastheniaMinnesota Multiphasic Personality InventorymedicinePersonalityMMPI-2PsychiatryBiological PsychiatryOriginal Researchmedia_commonExtraversion and introversionMMPI-2 childhood migraine maternal personality.business.industrymedicine.diseasematernal personalitySettore MED/39 - Neuropsichiatria InfantilePsychiatry and Mental healthMigraineAnxietymedicine.symptomPersonality Assessment InventorybusinessNeuropsychiatric Disease and Treatment
researchProduct

Recent epidemiological studies on ionizing radiation and childhood cancer in Germany.

1998

The results from recent epidemiological studies based on the German Childhood Cancer Registry are summarized.An oecological study covers 16 years' incidence of childhood malignancies in areas surrounding nuclear facilities and in matched control regions. Two population-based case control studies explore potential risk factors of childhood leukaemia in the state of Lower Saxony (1988 93) and in all western states of Germany (1992-94).There was no increased incidence of childhood leukaemia and other malignancies in the vicinity of nuclear installations. X-ray examinations during pregnancy and in early childhood were not associated with an increased risk of childhood leukaemia. There were no d…

medicine.medical_specialtyPediatricsNeoplasms Radiation-InducedPopulationCohort StudiesPregnancyRisk FactorsGermanyRadiation IonizingEpidemiologyMedicineHumansRadiology Nuclear Medicine and imagingEarly childhoodRisk factoreducationChildLeukemia Radiation-InducedChildhood Cancer Registryeducation.field_of_studyPregnancyRadiological and Ultrasound Technologybusiness.industryIncidence (epidemiology)Case-control studyRadiobiologymedicine.diseaseRadiographyCase-Control StudiesChild PreschoolPrenatal Exposure Delayed EffectsFemalebusinessRadioactive Hazard ReleasePower PlantsInternational journal of radiation biology
researchProduct

Family Context Assessment in Middle Childhood: A Tool Supporting Social, Educational, and Public Health Interventions

2021

Quality of the family context has an important role in the physical and mental health of children

medicine.medical_specialtyPsychometricsHealth Toxicology and Mutagenesismedia_common.quotation_subjectassessmentConcurrent validitylcsh:MedicineContext (language use)family contextArticlemiddle childhoodDevelopmental psychologyPromotion (rank)Surveys and QuestionnairesmedicineHumans0501 psychology and cognitive sciencesChildmedia_commonvalidationParentingPublic health05 social scienceslcsh:RPublic Health Environmental and Occupational Health050301 educationSocial environmentReproducibility of ResultsChild developmentMental healthConfirmatory factor analysisMental Healthpositive parentingEducational StatusFemalePublic HealthPsychology0503 education050104 developmental & child psychology
researchProduct

Manualized psychodynamic-interactional group therapy for the treatment of somatoform pain disorders.

2010

Medically unexplained and clinically significant symptoms of pain are highly prevalent in the general population. More than one third of all patients in general practices and various departments of hospitals suffer from somatoform disorders with pain being the main complaint of 70% of these patients. This treatment manual is the first disorder-specific, psychodynamically oriented treatment for these patients. Based on psychodynamic-interactional group psychotherapy, it focuses on disorder-specific aspects as well as on psychic and interpersonal problems which have resulted from adverse childhood experiences and insecure attachment. In three treatment phases comprising an “information and mo…

medicine.medical_specialtyPsychotherapistmedicine.medical_treatmentTransfer PsychologyPopulationPsychological interventionMEDLINEPainGroup psychotherapyLife Change EventsMind-Body Relations MetaphysicalInterpersonal relationshipManuals as TopicPatient Education as TopicmedicineHumansPain ManagementAffective SymptomsAdverse Childhood ExperienceseducationPsychiatrySomatoform Disorderseducation.field_of_studyCommunicationPsychodynamicsSocial relationPsychoanalytic TherapyPsychiatry and Mental healthClinical PsychologyTreatment OutcomeChronic DiseasePsychotherapy GroupPshychiatric Mental HealthPsychologyArousalBulletin of the Menninger Clinic
researchProduct

Musculoskeletal manifestations of childhood cancer and differential diagnosis with juvenile idiopathic arthritis (ONCOREUM): a multicentre, cross-sec…

2021

Summary Background Presenting symptoms of childhood cancers might mimic those of rheumatic diseases. However, the evidence available to guide differential diagnosis remains scarce. Preventing wrong or delayed diagnosis is therefore important to avoid incorrect administration of glucocorticoid or immunosuppressive therapy and worsening of prognosis. As such, we aimed to assess the prevalence and characteristics of presenting musculoskeletal manifestations in patients at cancer onset and to identify the factors that differentiate childhood malignancies with arthropathy from juvenile idiopathic arthritis. Methods We did a multicentre, cross-sectional study at 25 paediatric haemato-oncology cen…

medicine.medical_specialtybusiness.industryImmunologyArthritisCancerOdds ratioMusculoskeletal manifestationJuvenile idiopathic arthritismedicine.diseaseHistiocytosisRheumatologySettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAPrednisoneInternal medicineJoint painArthropathyMusculoskeletal manifestations childhood cancer juvenile idiopathic arthritismedicinechildhood cancerImmunology and AllergyDifferential diagnosismedicine.symptombusinessmedicine.drug
researchProduct

Physical activity promotion in public health nursing practice with children

2007

Background: Physical activity has become a major public health concern even in early childhood. This article exemplifies physical activity promotion in practice as described by public health nurses from Finnish primary health care. Method: We gathered the data by purposive sampling in five regional focus groups with 24 informants working in child health clinics provided for all families with children below school age. Statements associated with physical activity promotion were extracted out of verbatim transcripts. Frequency counting complemented qualitative analysis of the content of statements. Findings: Child-centred evaluation provided by public health nurses focused on motor developmen…

medicine.medical_specialtybusiness.industryPublic healthPublic Health Environmental and Occupational HealthPublic health nursingSpecial needsFocus groupHealth promotionNursingHealth careMedicineHealth educationEarly childhoodbusinessCare PlanningPrimary Health Care Research & Development
researchProduct

Parenting stress and impact of illness in parents of children with coeliac disease

2013

Coeliac disease (CD) is a chronic disease which could stress patients and their family. Although, poor attention has been paid to the quality of life in CD children and to the functioning of families with CD children. The study aims to evaluate the parenting perception of the CD impact and the parenting distress level. A group of 74 parents of CD children compiled the Impact Childhood Illness Scale and the Parenting Stress Index which is also compiled by 74 parents of health children. The assessment does not reveal a significant impact of CD on patient’s personal life although some critical areas emerged. Results evidenced an higher level of parenting stress in parents of CD children than p…

medicine.medical_specialtybusiness.industrylcsh:Rimpact childhood illnesslcsh:RJ1-570lcsh:MedicinePersonal lifeParenting stresslcsh:Pediatricsmedicine.diseasePediatricsArticleCoeliac diseaseparenting stress chronic diseaseDistresscoeliac disease parenting stress chronic disease impact childhood illnessChronic diseaseparenting stressmedicinecoeliac disease; parenting stress; chronic disease; impact childhood illnessPsychiatrybusinesschronic diseasecoeliac disease
researchProduct

Attention-deficit/hyperactivity disorder in adults: update on clinical presentation and care

2014

Attention-deficit/hyperactivity disorder (ADHD) is characterized by traitlike symptoms, with stable features frequently emerging in early childhood and persisting throughout adolescence and adulthood. The hallmarks are pervasive, developmentally inappropriate levels of inattention, hyperactivity and impulsivity leading to impairments in family life, social life, academic performance, and occupational functioning. Emotional lability is a commonly associated feature that is a further source of impairment. Diagnosis rests on a comprehensive assessment of developmental psychiatric history and current status, following DSM-5 guidelines on ADHD classification and diagnostic thresholds for adults.…

medicine.medical_specialtymedicine.medical_treatmentImpulsivitymedicine.diseaseFamily lifeCognitive behavioral therapyPsychiatry and Mental healthPsychiatric historyQuality of life (healthcare)medicineAttention deficit hyperactivity disorderNeurology (clinical)Effects of sleep deprivation on cognitive performanceEarly childhoodmedicine.symptomPsychiatryPsychologyClinical psychologyNeuropsychiatry
researchProduct

CRIANÇAS E EXÍLIO: RELATOS DE VIDA DE CRIANÇAS DA GUERRA CIVIL ESPANHOLA NA BÉLGICA

2018

Resumen Durante la Guerra Civil española (1936-1939) unos 5000 niños y niñas tuvieron que marchar al exilio, encontrando en Bélgica un nuevo hogar de acogida temporal. Al finalizar el conflicto bélico, la mayoría de ellos fueron repatriados y regresaron junto a sus familias o a centros benéfico-paternalistas franquistas. Alrededor de un millar no regresaron por diferentes motivos. Este artículo recoge el testimonio de una decena de estos “niños” hispano-belgas y sus familiares, acudiendo a la historia oral y a la memoria, para recuperar una parte de la historia de la educación y la infancia. El viaje, las colonias de acogida o la integración social, las relaciones con la familia, la escuela…

memóriamemoriaoral historyHistoria de la educaciónhistoria de la infancia; memoria; historial oral; guerra civil española; exiliohistoire de l'enfancehistorial oralhistória orall'exill'histoire oraleEducationmemorySpanish Civil WarexilemémoireGuerra Civil Espanholaexílioexiliola guerre civile espagnolehistória da infânciahistory of childhoodhistoria de la infanciaguerra civil española
researchProduct