Search results for " circular dichroism"

showing 10 items of 134 documents

Electrically Driven Magnetic Domain Wall Rotation in Multiferroic Heterostructures to Manipulate Suspended On-Chip Magnetic Particles

2015

In this work, we experimentally demonstrate deterministic electrically driven, strain-mediated domain wall (DW) rotation in ferromagnetic Ni rings fabricated on piezoelectric [Pb(Mg1/3Nb2/3)O3]0.66-[PbTiO3]0.34 (PMN-PT) substrates. While simultaneously imaging the Ni rings with X-ray magnetic circular dichroism photoemission electron microscopy, an electric field is applied across the PMN-PT substrate that induces strain in the ring structures, driving DW rotation around the ring toward the dominant PMN-PT strain axis by the inverse magnetostriction effect. The DW rotation we observe is analytically predicted using a fully coupled micromagnetic/elastodynamic multiphysics simulation, which v…

Domain wall (magnetism)Materials scienceFerromagnetismMagnetic domainCondensed matter physicsMagnetic circular dichroismElectric fieldGeneral EngineeringGeneral Physics and AstronomyMagnetic nanoparticlesGeneral Materials ScienceMagnetostrictionRotationACS Nano
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The new 5- or 6-azapyrimidine and cyanuric acid derivatives of L-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic space…

2011

Abstract We report on the synthesis of the novel types of cytosine and 5-azacytosine (1–9), uracil and 6-azauracil (13–18) and cyanuric acid (19–22) derivatives of l -ascorbic acid, and on their cytostatic activity evaluation in human malignant tumour cell lines vs. their cytotoxic effects on human normal fibroblasts (WI38). The CD spectra analysis revealed that cytosine (5 and 6), uracil (14–16), 6-azauracil (17) and cyanuric acid (21) derivatives of l -ascorbic acid bearing free amino group at ethylenic spacer existed as a racemic mixture of enantiomers, whereas L-ascorbic derivatives containing the C-5 substituted hydroxy group at the ethylenic spacer were obtained in (4R, 5S) enantiomer…

Double bondStereochemistryAscorbic AcidCrystallography X-Ray010402 general chemistry01 natural sciencesCell LineCytosineInhibitory Concentration 50Structure-Activity Relationship03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDrug DiscoveryHumansUracilta116Pharmacologychemistry.chemical_classificationTriazinespyrimidine and cyanuric acid derivatives; L-ascorbic acid; circular dichroism; cytostatic activity evaluation; X-ray diffractionOrganic ChemistryAbsolute configurationHydrogen BondingStereoisomerismUracilBiological activityHep G2 CellsGeneral MedicineFibroblastsCytostatic AgentsAscorbic acidpyrimidine and cyanuric acid derivatives ; L-ascorbic acid ; circular dichroism ; cytostatic activity evaluation ; X-ray diffraction ; cell cycle analysis0104 chemical sciences3. Good healthchemistry030220 oncology & carcinogenesisS Phase Cell Cycle CheckpointsMCF-7 CellsCyanuric acidCytosineLactoneHeLa Cells
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Optical and magneto‐optical studies of Mn‐activated LiBaF 3

2005

The photoluminescence (PL) of Mn-doped LiBaF3 shows a weak Mn2+ emission band at 710 nm; the corresponding excitation bands are between 210 and 620 nm. After X-irradiation the PL spectrum shows two new bands peaking at 600 and 670 nm that are tentatively assigned to perturbed Mn2+ emissions; the intensity of all PL bands is increased. Magnetic circular dichroism (MCD) and the MCD-detected electron paramagnetic resonance (EPR) measurements show that F-type centres are formed after X-irradiation. The EPR measurements indicate that there is a spatial correlation between the F-type centre and the Mn2+ dopant. (© 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

Emission bandPhotoluminescenceDopantMagnetic circular dichroismlawChemistryAnalytical chemistryElectron paramagnetic resonanceExcitationMagneto opticallaw.inventionphysica status solidi (c)
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Vibrational circular dichroism studies of exceptionally strong chirality inducers in liquid crystals.

2021

7,7′-Disubstituted 2,2′-methylenedioxy-1,1′-binaphthyls are highly efficient chirality inducers in nematic liquid crystals. The absolute configuration of these compounds is, however, hard to determine as they only crystallize as racemic mixtures. In this work a Vibrational Circular Dichroism (VCD) study is reported that provides an unambiguous determination of the absolute configuration of these compounds. An in-depth General Coupled Oscillator (GCO) analysis of the source of the VCD signal reveals that the unusual structure of these binaphthyl compounds inherently leads to strong and robust VCD bands. Combined with linear transit calculations, our VCD studies allow for the determination of…

FELIX Condensed Matter PhysicsMaterials scienceAbsolute configurationGeneral Physics and Astronomy02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciences/dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitationCrystallographyLiquid crystalVibrational circular dichroismPhysical and Theoretical Chemistry0210 nano-technologyChirality (chemistry)SDG 6 - Clean Water and SanitationPhysical chemistry chemical physics : PCCP
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Analysis of Vibrational Circular Dichroism Spectra of Peptides

2020

Vibrational circular dichroism (VCD) is one of the major spectroscopic tools to study peptides. Nevertheless, a full understanding of what determines the signs and intensities of VCD bands of these compounds in the amide I and amide II spectral regions is still far from complete. In the present work, we study the origin of these VCD signals using the general coupled oscillator (GCO) analysis, a novel approach that has recently been developed. We apply this approach to the ForValNHMe model peptide in both α-helix and β-sheet configurations. We show that the intense VCD signals observed in the amide I and amide II spectral regions essentially have the same underlying mechanism, namely, the th…

FELIX Condensed Matter PhysicsModels MolecularProtein Conformation alpha-HelicalMaterials science010304 chemical physicsCircular DichroismHydrogen Bonding010402 general chemistry01 natural sciencesMolecular physicsSpectral lineArticle0104 chemical sciencesSurfaces Coatings and Films0103 physical sciencesVibrational circular dichroismSmall peptideMaterials ChemistryProtein Conformation beta-StrandPhysical and Theoretical ChemistryPeptidesJournal of Physical Chemistry B
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Vibrational circular dichroism spectroscopy for probing the expression of chirality in mechanically planar chiral rotaxanes

2020

Mechanically interlocked molecules can exhibit molecular chirality that arises due to the mechanical bond rather than covalent stereogenic units. Developing applications of such systems is made challenging by the absence of techniques for assigning the absolute configuration of products and methods to probe how the mechanical stereogenic unit influences the spatial arrangements of the functional groups in solution. Here we demonstrate for the first time that Vibrational Circular Dichroism (VCD) can be used to not only discriminate between mechanical stereoisomers but also provide detailed information on their (co)conformations. The latter is particularly important as these molecules are now…

FELIX Condensed Matter PhysicsSDG 16 - PeaceMaterials scienceMechanical bond010405 organic chemistrySDG 16 - Peace Justice and Strong InstitutionsAbsolute configurationGeneral Chemistry010402 general chemistry/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutions01 natural sciencesJustice and Strong Institutions0104 chemical sciencesStereocenterChemistryChemical physicsCovalent bondVibrational circular dichroismMoleculeSpectroscopyChirality (chemistry)
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Self-Assembly of Supramolecular Polymers of N-Centered Triarylamine Trisamides in the Light of Circular Dichroism: Reaching Consensus between Electro…

2020

The self-assembly of chiral supramolecular polymers is an intricate process that spans a wide range of length scales. Circular dichroism techniques are ideal to study this process as they provide information on the molecular scale but are at the same time also sensitive probes of the long-range interactions that control the growth and morphology of these polymers. As yet, Electronic Circular Dichroism that uses electronic transitions as a probe has by far been the method of choice while Vibrational Circular Dichroism, which uses vibrational transitions to probe structure, is much less employed. Here, we report experimental and theoretical studies of the self-assembly of helical supramolecul…

FELIX Condensed Matter Physicschemistry.chemical_classificationCircular dichroismQuantitative Biology::BiomoleculesExtrapolationGeneral ChemistryPolymerElectron010402 general chemistry01 natural sciencesBiochemistryArticleCatalysis0104 chemical sciencesSupramolecular polymersColloid and Surface ChemistrychemistryChemical physicsAtomic electron transitionVibrational circular dichroismSelf-assembly
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Occurrence of Fusarium mycotoxins in Italian cereal and cereal products from organic farming.

2013

In the present study, the occurrence of eighteen mycotoxins, nine trichothecenes (deoxynivalenol, 3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, nivalenol, neosolaniol, diacetoxyscirpenol, fusarenon-X, T-2 toxin and HT-2 toxin), three zearalenones (zearalenone, α-zearalenol and β-zearalenol), and six emergent mycotoxins, beauvericin and five enniatins (A, A1, B, B1 and B4), was monitored in different Italian organic cereals and cereal products by using a liquid chromatography coupled to triple quadrupole mass spectrometry method. A total of 93 organic cereal samples (wheat, barley, rye and oat) were collected from Italy. Limits of quantification ranged from 5 to 15 μg/kg. 80% of analyze…

Fusariumorganic foodFood SafetyFood ContaminationMass spectrometrymedicine.disease_causeDiacetoxyscirpenolAnalytical Chemistrymycotoxin03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyFusariumGastric cancer Gastrokine-1 Pichia pastoris Recombinant synthesis Mass spectrometry Circular dichroism Fluorescence spectroscopy Limited proteolysis Cell proliferation.medicineFood scienceMycotoxinZearalenone030304 developmental biology2. Zero hunger0303 health sciencesOrganic AgriculturebiologyToxin04 agricultural and veterinary sciencesGeneral MedicineMycotoxinsbiology.organism_classification040401 food scienceBeauvericinchemistryAgronomyItalyEnniatinEdible GrainFood ScienceFood chemistry
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GUI Implementation of VCDtools, A Program to Analyze Computed Vibrational Circular Dichroism Spectra

2020

As computing power increases, vibrational circular dichroism (VCD) calculations on molecules of larger sizes and complexities become possible. At the same time, the spectra resulting from these computations become increasingly more cumbersome to analyze. Here, we describe the GUI implementation into the Amsterdam Density Functional (ADF) software package of VCDtools, a toolbox that provides a user-friendly means to analyze VCD spectra. Key features are the use of the generalized coupled oscillator analysis methods, as well as an easy visualization of the atomic electric and magnetic transition dipole moments which together provide detailed insight in the origin of the VCD intensity. Using s…

General Chemical EngineeringComputationLibrary and Information Sciences01 natural sciencesSpectral lineArticle0103 physical sciencesSDG 7 - Affordable and Clean EnergyAnalysis methodFELIX Condensed Matter PhysicsPhysics/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy010304 chemical physicsCircular DichroismStereoisomerismGeneral ChemistryKey featuresSoftware package0104 chemical sciencesComputer Science ApplicationsVisualizationComputational physics010404 medicinal & biomolecular chemistryDipoleVibrational circular dichroismSoftwareJournal of Chemical Information and Modeling
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Multiplet coupling and band structure in L2,3-edge XAS through multi-channel multiple scattering theory.

2009

International audience; Using the recently developed multi-channel multiple scattering (MCMS) method we have calculated the x-ray absorption spectra (XAS) at the L2,3-edge of transition metal compounds. The MCMS method is an ab initio scheme which combines an accurate description of the band structure of the material with a correlated many-electron wave function on the absorber atom. Thereby configuration interaction in the XAS final state, in particular multiplet effects, can be taken into account. In the present implementation, we use an electron-hole wave function and treat the interaction with all other electrons on a mean-field level. The calculated spectra agree well with experiment f…

HistoryChemistryMagnetic circular dichroismScatteringAb initio02 engineering and technologyConfiguration interaction021001 nanoscience & nanotechnology7. Clean energy01 natural sciencesSpectral lineComputer Science ApplicationsEducationCondensed Matter::Materials Science0103 physical sciencesAtomic physics010306 general physics0210 nano-technologyElectronic band structureGround stateMultiplet
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