Search results for " cohort study"

showing 10 items of 3126 documents

Epidemiology of the sarcomas of the jaws in a Peruvian population

2010

Objective: Analysis of the clinical characteristics of patients with Sarcomas of the Jaws treated in the “Instituto Nacional de Enfermedades Neoplasicas. Dr. Eduardo Caceres Graziani” from 1952-2007. Study Design: Review of 155 clinical records of patients with Sarcomas of the Jaws and record of age, gender, size, location, clinical symptoms and signs, histopathological diagnoses and type of treatment. The data obtained were analyzed by means of Student’s statistical t-test, Fisher and Friedman’s test. Results: Analysis of 155 Sarcomas of the Jaws. The average age of patients was 36.8 years old (range: 1-80 years); the female gender was the most frequent (52.9%); the average tumor size was …

AdultMalemedicine.medical_specialtyAdolescentEstudios transversalesPopulationJaw neoplasmYoung Adultstomatognathic systemNeoplasias mandibularesEpidemiologyPerumedicineEpidemiologíaHumansYoung adulteducationChildGeneral DentistryAgedRetrospective StudiesAged 80 and overeducation.field_of_studyOral Medicine and Pathologybusiness.industryInfantRetrospective cohort studySarcomaMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyJaw NeoplasmsSurgerystomatognathic diseasesCross-Sectional StudiesOtorhinolaryngologyChild PreschoolUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleSarcomaChondrosarcomabusinessFacial symmetry
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The challenges of monoaxial bone transport in orthopedics and traumatology

2017

Background. Bone defects represent the main challenging problem for the orthopedic surgeon and, consequently, they increase the duration of hospitalization, risk of complications and health expenditures. The aim of our observational, descriptive and retrospective study is to evaluate the outcomes of patients treated with a mo­nolateral external fixator for bone defects greater than 3 cm. Material and methods. Between January 2003 and January 2013, 21 patients were treated at our center by bone transfer with a monolateral external fixator. The main etiologies were trauma in 17 cases (80.9%) and tumors in 4 cases (19.1%). Mean follow-up was 5 years for non-union and 3 years for tumors. Our cl…

AdultMalemedicine.medical_specialtyAdolescentExternal Fixatorsmedicine.medical_treatmentMonolateral external fixationTraumatologyIlizarov TechniqueBone NailsBone InfectionBone defects; Bone infection; Bone transport; Monolateral external fixation; Skeletal tumor;03 medical and health sciencesExternal fixationYoung Adult0302 clinical medicinemedicineHumansOrthopedics and Sports MedicineOrthopedic ProceduresRetrospective StudiesSkeletal tumorbusiness.industryRehabilitationBone transportRetrospective cohort studyMiddle AgedSurgeryTibial FracturesOrthopedicsTreatment OutcomeAmputationTraumatology030220 oncology & carcinogenesisOrthopedic surgeryObservational studyFemaleSplint (medicine)businessBone defects030217 neurology & neurosurgeryBone infection
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Early Results of Fissurectomy and Advancement Flap for Resistant Chronic Anal Fissure without Hypertonia of the Internal Anal Sphincter

2010

The aim of this study was to assess the efficacy of fissurectomy with skin advancement flap in healing chronic anal fissures without hypertonia of the internal anal sphincter. Twenty-six consecutive patients who failed healing after well-practiced topical medical therapy were enrolled. Anorectal manometry was performed preoperative and 6 months postoperatively. All patients were treated with fissurectomy and advancement flap through healthy skin tissue. All patients healed completely within 30 days from operation. The intensity and the duration of pain post-defecation was reduced significantly with respect to the preoperative values starting from the first defecation. One patient suffered …

AdultMalemedicine.medical_specialtyAdolescentFissurectomy Resistant Chronic Anal FissureAnal CanalSurgical FlapsInternal anal sphincterYoung AdultFissurectomy with skin advancement flapMuscle HypertoniaMuscle HypertoniamedicineHumansPostoperative PeriodProspective StudiesDefecationProspective cohort studyDigestive System Surgical ProceduresAnal fissureFissures without hypertoniabusiness.industryUrinary retentionAnorectal manometryFissurectomy with skin advancement flap Fissures without hypertonia Surgery.General MedicineMiddle AgedPlastic Surgery Proceduresmedicine.diseaseSurgerySettore MED/18 - Chirurgia GeneraleTreatment OutcomeChronic DiseaseDefecationHypertoniaSurgeryFemaleFissure in Anomedicine.symptombusinessFollow-Up StudiesThe American Surgeon
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Limitations of the trail making test part-B in assessing frontal executive dysfunction.

2015

AbstractPart B of the Trail Making Test (TMT-B) is one of the most widely used neuropsychological tests of “executive” function. A commonly held assumption is that the TMT-B can be used to detect frontal executive dysfunction. However, so far, research evidence has been limited and somewhat inconclusive. In this retrospective study, performance on the TMT-B of 55 patients with known focal frontal lesions, 27 patients with focal non-frontal lesions and 70 healthy controls was compared. Completion time and the number of errors made were examined. Patients with frontal and non-frontal lesions performed significantly worse than healthy controls for both completion time and the number of errors.…

AdultMalemedicine.medical_specialtyAdolescentFrontal lobesTrail Making TestAudiologyCognition DisorderExecutive FunctionYoung AdultExecutive functionNeuropsychologyBrain InjuriemedicineHumansYoung adultPsychiatryBrain diseaseAgedAged 80 and overTrail Making TestFocal lesionsGeneral NeuroscienceSignificant differenceNeuropsychologyRetrospective cohort studyMiddle AgedFrontal LobePsychiatry and Mental healthClinical PsychologyFrontal lobeBrain InjuriesCase-Control StudiesNeuropsychological testsFemaleBrain diseasesNeurology (clinical)Completion timePsychologyCase-Control StudieCognition Disordershuman activitiesExecutive dysfunctionHumanJournal of the International Neuropsychological Society : JINS
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Endoscopic and histological findings in the duodenum of adults with celiac disease before and after changing to a gluten-free diet: a 2-year prospect…

2006

Published follow-up data on small-intestinal recovery in patients with celiac disease are scarce and contradictory. This is especially the case for adult patients, who often show incomplete histological recovery after starting a gluten-free diet (GFD). We conducted a 2-year prospective study to evaluate the effectiveness of a GFD in improving the endoscopic and histological duodenal findings in adults with celiac disease.We studied 42 consecutive adults with newly diagnosed celiac disease (13 men, 29 women; mean age 32.7 years, range 15 - 72 years). All the patients underwent esophagogastroduodenoscopy and small-bowel biopsy. We devised our own grading system for the endoscopic appearance o…

AdultMalemedicine.medical_specialtyAdolescentGlutensDuodenumGastroenterologyInternal medicineBiopsyDuodenal bulbmedicineHumansDuodenoscopyIntestinal MucosaProspective cohort studyDuodenoscopyAgedmedicine.diagnostic_testEsophagogastroduodenoscopybusiness.industryGastroenterologyMiddle AgedSurgeryClinical trialCeliac Diseasemedicine.anatomical_structureDuodenumGluten freeFemalebusinessFollow-Up StudiesEndoscopy
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Management of cerebrospinal fluid otorrhea.

2013

Abstract Introduction Cerebrospinal fluid otorrhea results from an abnormal communication between the subarachnoid space and tympanomastoid compartment; most of them are of traumatic aetiology. They have clinical interest due to the potential risk of meningitis, directly related to the aetiology. Our aim was to show our experience in the management of this process. Methods A total of 17 patients were diagnosed and treated for cerebrospinal fluid otorrhea from 2003 to 2011. Results In our study, the highest percentage of cases was spontaneous cerebrospinal fluid otorrhea, with a wide clinical presentation. The diagnosis was based on the determination of beta-2-transferrin and radiological st…

AdultMalemedicine.medical_specialtyAdolescentHearing lossmedicine.medical_treatmentMastoidectomyYoung AdultmedicineCerebrospinal Fluid OtorrheaHumansAgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryCerebrospinal Fluid OtorrheaMagnetic resonance imagingRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureEtiologyFemalemedicine.symptomSubarachnoid spacebusinessMeningitisActa otorrinolaringologica espanola
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Effectiveness of the 2010–2011 seasonal influenza vaccine in preventing confirmed influenza hospitalizations in adults: A case–case comparison, case-…

2012

Highlights ► We perform a case–case comparison as an improvement of the test-negative design. ► We report IVE estimates with a low probability of bias. ► Influenza vaccination halved the risk of confirmed influenza hospitalization. ► This effect was consistent regardless of age over 60. ► The measured effect was specific for confirmed influenza hospitalizations.

AdultMalemedicine.medical_specialtyAdolescentInfluenza vaccineCase-control studiesArticleSeasonal influenzaYoung AdultInfluenza Human/epidemiologyInternal medicineInfluenza HumanMedicineHumansProspective StudiesYoung adultProspective cohort studyIntensive care medicineReverse transcriptase polymerase chain reactionAgedHospitalizationsGeneral VeterinaryGeneral Immunology and Microbiologybusiness.industryCase comparisonVaccinationPublic Health Environmental and Occupational HealthCase-control studyvirus diseasesMiddle AgedConfidence intervalVaccinationHospitalizationInfectious DiseasesInfluenza vaccinesRisk factorsVaccines InactivatedSpainMolecular MedicineFemalebusinessRespiratory syncytial virus infections/epidemiologyVaccine
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Oral peripheral ameloblastoma: A retrospective series study of 25 cases

2018

Background Peripheral ameloblastoma (PA) is a rare and unusual variant of odontogenic tumor, which was described only in isolated case reports in literature. The objective of this study was to investigate the clinical profile, treatment and outcome of PA in a consecutive case series. Material and Methods A total of 25 patients with histologically confirmed PA from 2001 to 2015 were retrospectively reviewed in our institution. Results Of the 25 patients, 22 males and 3 females were identified (male: female = 7.3:1). The average age was 48.3 years (range 11-81 years) with lingual or palate gingival region being the most common site (76%). The course of disease was less than 6 months in 92.0% …

AdultMalemedicine.medical_specialtyAdolescentLesionAmeloblastoma03 medical and health sciencesYoung Adult0302 clinical medicinePeripheral ameloblastomaMedicineHumansYoung adultChildGeneral DentistryAgedRetrospective StudiesAged 80 and overSeries (stratigraphy)Oral Medicine and PathologyGingival Neoplasmsbusiness.industryResearchOdontogenic tumorRetrospective cohort study030206 dentistryConsecutive case seriesMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]SurgeryOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASSurgeryFemaleDifferential diagnosismedicine.symptombusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Clinical features of oral lichen planus. A retrospective study of 65 cases

2010

Objectives: To describe the clinical features of patients diagnosed with oral lichen planus (OLP) and to establish the prevalence of its malignant transformation in our setting. Study design: A retrospective study was made of 65 patients clinically and histologically diagnosed with OLP in the Service of Oral Surgery (Dental Clinic of the University of Barcelona, Spain) in the period 1990-2005. A descriptive and bivariate statistical analysis was made. Results: The mean patient age was 59 years (SD ± 14.9). Most of the patients (61%) were women, and the most frequent location of the lesions was the buccal mucosa (90.8%). White forms of OLP were noted in 66% of the cases, and 46.2% of the pat…

AdultMalemedicine.medical_specialtyAdolescentLichensAlcohol abuseMalalties de la bocaChronic liver diseaseBuccal mucosaYoung AdultHepatitis víricastomatognathic systemDiabetes mellitusStatistical significanceTabacTobaccomedicineHumansLíquensViral hepatitisGeneral DentistryAgedRetrospective StudiesAged 80 and overbusiness.industryRetrospective cohort studyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologySurgerystomatognathic diseasesMouth diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASPopulation studySurgeryOral lichen planusFemalebusinessLichen Planus Oral
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Efficacy of acupuncture for the prophylaxis of migraine: a multicentre randomised controlled clinical trial.

2006

Our aim was to assess the efficacy of a part-standardised verum acupuncture procedure, in accordance with the rules of traditional Chinese medicine, compared with that of part-standardised sham acupuncture and standard migraine prophylaxis with beta blockers, calcium-channel blockers, or antiepileptic drugs in the reduction of migraine days 26 weeks after the start of treatment.This study was a prospective, randomised, multicentre, double-blind, parallel-group, controlled, clinical trial, undertaken between April 2002 and July 2005. Patients who had two to six migraine attacks per month were randomly assigned verum acupuncture (n=313), sham acupuncture (n=339), or standard therapy (n=308). …

AdultMalemedicine.medical_specialtyAdolescentMigraine DisordersPopulationAcupuncture TherapyTraditional Chinese medicinelaw.inventionRandomized controlled trialDouble-Blind MethodlawInternal medicineAcupuncturemedicineConfidence IntervalsOdds RatioHumansProspective StudieseducationProspective cohort studyAgedRetrospective Studieseducation.field_of_studybusiness.industryRetrospective cohort studyMiddle Agedmedicine.diseaseClinical trialTreatment OutcomeMigrainePhysical therapyFemaleNeurology (clinical)businessThe Lancet. Neurology
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