Search results for " covid-19."

showing 10 items of 453 documents

Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020

2020

Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.

MalePediatricsEpidemiologyProtease InhibitorComorbiditymedicine.disease_causeClinical Laboratory TechniqueSevere Acute Respiratory SyndromeDisease OutbreaksFeces0302 clinical medicineSettore MED/38 - Pediatria Generale E SpecialisticaCOVID-19 TestingRetrospective StudiePandemic030212 general & internal medicineViralChildCoronavirusPediatricDisease OutbreakCoinfectionHospitals PediatricSettore MED/38HospitalsDiarrheaTreatment OutcomeSARS-CoV-2 infection; children; covid-19; hydroxychloroquine; pneumonia; Adolescent; Antiviral Agents; Betacoronavirus; COVID-19; COVID-19 Testing; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; SARS-CoV-2; Severe Acute Respiratory Syndrome; Treatment OutcomeItalyChild PreschoolCoinfectionFemalemedicine.symptomCoronavirus InfectionsRapid CommunicationHumanDiarrheamedicine.medical_specialtyCOVID-19; ItalyhydroxychloroquineAdolescentFeverCoronaviruPneumonia ViralAntiviral Agents03 medical and health sciencesBetacoronavirusImmunocompromised Hostchildren030225 pediatricsVirologyIntensive caremedicineHumanspneumoniaProtease InhibitorsPreschoolPandemicsRetrospective StudiesAntiviral Agentchildren; covid-19; hydroxychloroquine; pneumonia; SARS-CoV-2 infection; Adolescent; Antiviral Agents; Betacoronavirus; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; Severe Acute Respiratory Syndrome; Treatment OutcomeNoninvasive VentilationBetacoronaviruPandemicbusiness.industryClinical Laboratory TechniquesCoronavirus InfectionSARS-CoV-2pneumonia.SARS-CoV-2 infectionPublic Health Environmental and Occupational HealthInfant NewbornCOVID-19InfantRetrospective cohort studymedicine.diseaseNewbornComorbidityCoronavirusPneumoniaChronic DiseaseFecebusiness
researchProduct

A 7-Year-Old Boy and a 14-Year-Old Girl Initially Diagnosed with Toxic Shock Syndrome and Tested Positive for SARS-CoV-2 Infection, Supporting a Diag…

2021

Case series Patients: Male, 7-year-old • Female, 14-year-old Final Diagnosis: Multisystem inflammatory syndrome in children (MIS-C) Symptoms: Muscular weakness • shock Medication: — Clinical Procedure: — Specialty: Critical Care Medicine • Infectious Diseases • Pediatrics and Neonatology • Rheumatology Objective: Unusual clinical course Background: Multisystem inflammatory syndrome in children (MIS-C) has recently been described in children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This report describes 2 children with MIS-C who were initially diagnosed with toxic shock syndrome but who tested positive for SARS-CoV-2 infection on reverse transcription-polym…

MalePediatricsmedicine.medical_specialtyCOVID-19 Related Immunoglobulins Intravenous Mucocutaneous Lymph Node Syndrome Pediatric Multisystem Inflammatory Disease Adolescent COVID-19 Testing Child Female Humans Male Pandemics SARS-CoV-2 Systemic Inflammatory Response Syndrome COVID-19 Shock SepticAdolescentMucocutaneous Lymph Node SyndromeTachypneaPericardial effusionCOVID-19 TestingOliguriamedicineHumansPediatric Multisystem Inflammatory Disease COVID-19 RelatedChildPandemicsbusiness.industrySARS-CoV-2Toxic shock syndromeImmunoglobulins IntravenousCOVID-19General MedicineArticlesmedicine.diseaseShock SepticSystemic Inflammatory Response SyndromeSystemic inflammatory response syndromePneumoniaMethylprednisoloneMacrophage activation syndromeFemalemedicine.symptombusinessmedicine.drugThe American Journal of Case Reports
researchProduct

Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study

2020

AbstractEvidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, gender and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

MalePediatricsmedicine.medical_specialtyScienceDiseasesComorbidityDisease030204 cardiovascular system & hematologyCOVID-19 ; Medical research ; Diseases ; Risk factorsAged Aged 80 and over COVID-19 Comorbidity Diabetes Mellitus Ethnicity Female Humans Hypertension Male Middle Aged Obesity Pandemics Risk Factors Romania SARS-CoV-2Article03 medical and health sciencesMedical research0302 clinical medicineDiabetes mellitusDiabetes MellitusEthnicitymedicineHumansObesity030212 general & internal medicinePandemicsAgedAged 80 and overMultidisciplinaryRomaniaSARS-CoV-2business.industryQRCOVID-19Retrospective cohort studyMiddle Agedmedicine.diseaseComorbidityObesityClinical trialRisk factorsHypertensionMedicineFemaleObservational studybusinessKidney disease
researchProduct

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortalit…

2021

Background: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-…

MalePerinatal careNewborn careSTILLBIRTHSRJ101UNDER-5 MORTALITYPsychological intervention010501 environmental sciencesInfant mortalityGlobal Health01 natural sciences0302 clinical medicineRA0421Cause of DeathInfant MortalityGlobal healthLife TablesHealthcare improvements030212 general & internal medicine610 Medicine & healthChildCause of Death; Child; COVID-19; Global Health; Humans; Infant; Life Tables; SARS-CoV-2; Sustainable Development11 Medical and Health SciencesCause of deathLife TableMortality rate1. No povertyPublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineArticlesHälsovetenskaperSustainable DevelopmentMortality analyses3. Good healthPeer reviewChild PreschoolSDG 1 - No PovertyChild MortalityFemaleLife Sciences & BiomedicineHumanChild mortalityCOUNTRIESDEATHSInfants -- MortalitatGBD610 Medicine & health03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingLife tablesunder-5 mortality rateGeneral & Internal MedicineHealth SciencesNeonatal deathsmedicineSYSTEMATIC ANALYSISHumans:Medicine [Science]Infants -- SalutPreschool0105 earth and related environmental sciencesScience & TechnologyInfants nadons -- Salutbusiness.industrySARS-CoV-2Infants nadons -- MortalitatINFORMInfant NewbornCOVID-19InfantNeonatal and child health ; Sustainable Development Goal 3.2 ; Global healthGBD 2019 Under-5 Mortality Collaboratorsmedicine.diseaseNewbornTRENDSInfant mortalitySustainable Development GoalChild mortalityFolkhälsovetenskap global hälsa socialmedicin och epidemiologiDeaths3121 General medicine internal medicine and other clinical medicineRGbusinessSystematic AnalysisMalariaDemography
researchProduct

COVID-19 infection: comparing the knowledge, attitude and practices in a sample of nursing students.

2020

Background: SARS-CoV-2 infection is a global health problem that is primarily detected in Italy with progressive increase in cases and deaths. To facilitate the management of the pandemic in Italy, it is essential to understand the level of attention on COVID-19. The aim of the study was to evaluate the knowledge, attitude and practices towards SARS-CoV-2 among the nursing students of University of Palermo during the rapid rise period of the COVID-19 pandemic. Methods: The current study was a cross-sectional study. On-line questionnaires were used for the collection of the data by providing a survey in all nursing students. The questionnaire consisted of two parts: demographics and Knowledg…

MalePracticeOriginal Article: Nursing Students' PopulationAttitude of Health PersonnelCOVID-19University studentsYoung AdultCross-Sectional StudiesKnowledgeItalyAttitudeSurveys and QuestionnairesHumansFemaleStudents NursingClinical CompetencePandemicsKnowledge Attitude Practice COVID-19 Italy University studentsActa bio-medica : Atenei Parmensis
researchProduct

Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

2021

Association of Surgeons in Training Surgical Summit, online, 17 Oct 2020 - 17 Oct 2020 2021 Virtual Annual Meeting / Surgical Research Society, online, 24 Mar 2021 - 25 Mar 2021, National Research Collaborative Meeting, online, 10 Dec 2020 - 10 Dec 2020, Royal Australasian College of Surgeons Annual Academic Surgery Conference, online, 5 Nov 2020 - 5 Nov 2020; The British journal of surgery : BJS 108(12), 1448-1464 (2021). doi:10.1093/bjs/znab336

MaleRespiration Artificial/statistics & numerical dataSettore MED/18 - CHIRURGIA GENERALEeducation-Sciences du Vivant [q-bio]/Médecine humaine et pathologieAbdominal NeoplasmPostoperative Complications/mortalityNOsurgeryCohort Studies03 medical and health sciencesCOVID-19; death; SARS-CoV-2; surgery0302 clinical medicinePostoperative ComplicationsdeathHumans030212 general & internal medicinePandemicsAbdominal Neoplasms/surgeryAgedLS7_4COVID-19/mortalityRespiratory Distress SyndromePandemicSARS-CoV-2Respirationsurgical procedures operativemortalitysurgery specialtypandemicspulmonary complicationssars-cov-2covid-19coronavirus pandemicCOVID-19Middle Aged3126 Surgery anesthesiology intensive care radiologyRespiration Artificialsurgical proceduresoperativemortalitysurgery specialtypandemicspulmonary complicationssars-cov-2covid-19coronavirus pandemicAbdominal Neoplasms; Aged; COVID-19; Cohort Studies; Female; Humans; Male; Middle Aged; Pandemics; Postoperative Complications; Respiration Artificial; Respiratory Distress Syndrome; Elective Surgical ProceduresElective Surgical Procedures030220 oncology & carcinogenesisAbdominal NeoplasmsArtificialFemalePostoperative ComplicationCohort Studie[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyRespiratory Distress Syndrome/mortalityHuman
researchProduct

A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

2021

© The Author(s), under exclusive licence to Springer Nature Limited 2021, corrected publication 2022

MaleSTRESSEmotionsPsychological interventionSocial Sciences[SHS.PSY]Humanities and Social Sciences/PsychologyREAPPRAISAL INTERVENTIONSBehavioral neuroscienceNEGATIVE AND POSITIVE EMOTIONSBehavioral Neuroscience0302 clinical medicineddc:150[STAT.ML]Statistics [stat]/Machine Learning [stat.ML]PandemicPsychologyANXIETYCovid-19 reappraisal emotionsR PACKAGE//purl.org/becyt/ford/5.1 [https]ComputingMilieux_MISCELLANEOUSRepurposingmedia_common//purl.org/becyt/ford/5 [https]05 social sciencesDIVERGENT ASSOCIATIONSPOSITIVE EMOTIONS3. Good health[SCCO.PSYC]Cognitive science/PsychologyMULTI-COUNTRY TESTadult; COVID-19; female; humans; male; emotional regulation; emotions/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingAnxietyFemaleCOGNITIVE REAPPRAISALPsychological resiliencemedicine.symptomPsychology[STAT.ME]Statistics [stat]/Methodology [stat.ME]Clinical psychologyAdultSocial Psychologymedia_common.quotation_subjectExperimental and Cognitive PsychologyArticle050105 experimental psychologyCognitive reappraisal03 medical and health sciencesSDG 3 - Good Health and Well-beingHuman behaviourmedicineHumans0501 psychology and cognitive sciencesMETAANALYSISBehaviour Change and Well-beingpandemicCOVID-19reappraisalRESILIENCENEGATIVE AFFECTMental healthEmotional RegulationREGULATION STRATEGIES030217 neurology & neurosurgeryNature Human Behaviour
researchProduct

Examining Anxiety, Sleep Quality, and Physical Activity as Predictors of Depression among University Students from Saudi Arabia during the Second Wav…

2022

Conducted during the second wave of the pandemic, this cross-sectional study examined the link between sleep quality, physical activity, exposure, and the impact of COVID-19 as predictors of mental health in Saudi undergraduate students. A convenience sample of 207 participants were recruited, 89% of whom were females and 94% were single. The measures included questionnaires on the level of exposure and the perceived impact of COVID-19, a physical activity measure, GAD-7, PHQ-9, and PSQI. The results indicated that approximately 43% of participants exhibited moderate anxiety, and 50% were at risk of depression. Overall, 63.93% of students exposed to strict quarantine for at least 14 days (n…

MaleUniversitiesDepressionHealth Toxicology and MutagenesisSaudi ArabiaPublic Health Environmental and Occupational HealthCOVID-19Anxietydepression; anxiety; COVID-19; sleep quality; mental health; university counseling services; Saudi ArabiaCross-Sectional StudiesSleep QualityHumansFemaleStudentsExercisePandemicsInternational Journal of Environmental Research and Public Health
researchProduct

Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study

2021

Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231…

MaleVascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERinfectious diseases0302 clinical medicine030202 anesthesiologyAnesthesiologyCirugía80 and overProspective StudiesYoung adultChildLungAged 80 and overCOVID-19 ; delay ; SARS-CoV-2 ; surgery ; timingSARS‐CoV‐2 infectionOperativeChild PreschoolPneumonia & InfluenzaInfectionCohort studyHumanmedicine.medical_specialtydelayClinical SciencesSars-cov-2GlobalSurg CollaborativeSettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE03 medical and health sciencesClinical ResearchAnesthesiologyBiodefenseCorrespondence617HumansPULMONARY COMPLICATIONSCRIANÇAS EM IDADE PRÉ-ESCOLARAgedScience & TechnologyCirurgiaPreventionCOVID-19; SARS-CoV-2; delay; surgery; timingInfantOdds ratioPneumoniaProspective StudieClinical research/dk/atira/pure/core/keywords/uob_covid19SurgeryHuman medicine610 Medizin und Gesundheit1109 NeurosciencesInternationalitySettore MED/29 - CHIRURGIA MAXILLOFACCIALESettore MED/18 - CHIRURGIA GENERALECOVID-19; delay; SARS-CoV-2; surgery; timing; Adolescent; Adult; Aged; Aged 80 and over; Child; Child Preschool; Cohort Studies; Female; Humans; Infant; Male; Middle Aged; Prospective Studies; SARS-CoV-2; Surgical Procedures Operative; Time; Young Adult; COVID-19; Internationality; Practice Guidelines as TopicgastroenterologyCohort StudiessurgeryMedicine and Health Sciencestiming030212 general & internal medicineProspective cohort studyMortality rateCOVID-19; delay; SARS-CoV-2; surgery; timingCovid19Middle AgedInfectious DiseasesSurgical Procedures OperativePractice Guidelines as TopicFemalePatient Safetymedicine.symptom6.4 SurgeryLife Sciences & BiomedicineAdult61Adolescent610 Medicine & healthCOVID-19 SARS-CoV-2 delay surgery timingAsymptomaticNOCOVIDSurg CollaborativeTimeVaccine RelatedYoung AdultAll institutes and research themes of the Radboud University Medical CentermedicineMortalitatddc:610MortalityPreschoolLS7_4Surgical Proceduresbusiness.industrySARS-CoV-2NeurosciencesEvaluation of treatments and therapeutic interventionsCOVID-191103 Clinical Sciences3126 Surgery anesthesiology intensive care radiologySurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Anesthesiology and Pain MedicineEmerging Infectious DiseasesGood Health and Well BeingMortalidadCohort Studiebusiness
researchProduct

Utility of lateral flow tests in SARS-CoV-2 infection monitorization

2020

Introduction. The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19-COVID cases once the virus has been cleared. We analyzed the usefulness of the SARS-CoV-2 rapid test of Autobio and tried to correlate its pattern with the severity of COVID19 infection. Material and methods. We analyzed the accuracy and clinical usefulness of a point-of-care IgM and/or IgG test for SARS-CoV-2 in 35 COVID-19 patients [12 (34.3%) mild-moderate and 23 (65.7%) severe-critical] admitted to a field hospital in Madrid, as well as i…

Malebandas débilmente positivas0301 basic medicineTime FactorsOriginalCross-sectional studyinfección por COVID-19weak positive bandsDiseaseAntibodies ViralSeverity of Illness IndexSerologyCOVID-19 Testing0302 clinical medicineSerologic rapid tests030212 general & internal medicineAsymptomatic InfectionsImmunoassaybiologyReverse Transcriptase Polymerase Chain ReactionGeneral MedicineMiddle AgedPoint-of-Care TestingFemaleSymptom Assessmentmedicine.symptomAntibodyCoronavirus InfectionsAdultMicrobiology (medical)medicine.medical_specialtyPoint-of-care testingPneumonia ViralSensitivity and SpecificityAsymptomaticVirusBetacoronavirus03 medical and health sciencesInternal medicineSeverity of illnessmedicineHumanstest serológicos rápidosPandemicsAgedPharmacologyClinical Laboratory TechniquesSARS-CoV-2business.industryCOVID-19COVID-19 infectionCross-Sectional Studies030104 developmental biologyImmunoglobulin MAutobioImmunoglobulin Gbiology.proteinbusinessRevista Española de Quimioterapia
researchProduct