6533b858fe1ef96bd12b58ad
RESEARCH PRODUCT
Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020
S. GarazzinoC. MontagnaniD. DonaA. MeiniE. FeliciG. VergineS. BernardiR. GiaccheroA. L. VecchioP. MarchisioG. NicoliniL. PierantoniI. RabboneG. BanderaliM. DeninaE. VenturiniA. KrzysztofiakR. BadolatoS. BianchiniL. GalliA. VillaniG. Castelli-gattinaraF. SalviniL. AbbagnatoE. CastagnolaI. DodiC. GhittiP. LippiR. AgostinianiS. CherubiniP. ValentiniP. GianinoA. VaccaroP. ManzoniP. VernaP. ComberiatiP. Di FilippoP. GalliaG. BattezzatiL. FioreC. DalmazzoE. TappiM. LazzeriniP. -A. TovoC. ScolfaroG. PruccoliU. RamenghiC. GiaquintoL. Da DaltG. TorneseP. BerleseA. PlebaniE. C. MannoV. SantilliL. LancellaL. CursiA. CampanaE. BozzolaS. BosisM. LanariC. PecoraroP. Del BarbaE. NicastroS. EspositoG. V. ZuccottiG. CorselloF. CardinaleA. M. ToccoG. BallardiniC. AgostoniE. ChiappiniG. IndolfiB. AnnaS. CazzatoG. ZavariseC. PignataF. Marchettisubject
MalePediatricsEpidemiologyProtease InhibitorComorbiditymedicine.disease_causeClinical Laboratory TechniqueSevere Acute Respiratory SyndromeDisease OutbreaksFeces0302 clinical medicineSettore MED/38 - Pediatria Generale E SpecialisticaCOVID-19 TestingRetrospective StudiePandemic030212 general & internal medicineViralChildCoronavirusPediatricDisease OutbreakCoinfectionHospitals PediatricSettore MED/38HospitalsDiarrheaTreatment OutcomeSARS-CoV-2 infection; children; covid-19; hydroxychloroquine; pneumonia; Adolescent; Antiviral Agents; Betacoronavirus; COVID-19; COVID-19 Testing; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; SARS-CoV-2; Severe Acute Respiratory Syndrome; Treatment OutcomeItalyChild PreschoolCoinfectionFemalemedicine.symptomCoronavirus InfectionsRapid CommunicationHumanDiarrheamedicine.medical_specialtyCOVID-19; ItalyhydroxychloroquineAdolescentFeverCoronaviruPneumonia ViralAntiviral Agents03 medical and health sciencesBetacoronavirusImmunocompromised Hostchildren030225 pediatricsVirologyIntensive caremedicineHumanspneumoniaProtease InhibitorsPreschoolPandemicsRetrospective StudiesAntiviral Agentchildren; covid-19; hydroxychloroquine; pneumonia; SARS-CoV-2 infection; Adolescent; Antiviral Agents; Betacoronavirus; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; Severe Acute Respiratory Syndrome; Treatment OutcomeNoninvasive VentilationBetacoronaviruPandemicbusiness.industryClinical Laboratory TechniquesCoronavirus InfectionSARS-CoV-2pneumonia.SARS-CoV-2 infectionPublic Health Environmental and Occupational HealthInfant NewbornCOVID-19InfantRetrospective cohort studymedicine.diseaseNewbornComorbidityCoronavirusPneumoniaChronic DiseaseFecebusinessdescription
Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-05-07 |