Search results for " cross-sectional studies"

showing 10 items of 133 documents

Non respiratory symptoms in asthma as possible predictors of exacerbations

2015

Anxiety 34 37 36 Headache 28 23 26 Abdominal pain 1 3 2 Weakness 13 4 9 Depression 5 0 3 Impaired sleep 4 8 7 Nicturia 7 0 5 Chest pain 11 7 9 Excitement 13 6 10 Nonlocalized pain 4 4 4 Hunger 3 4 3 Lack of appetite 5 5 5 Fever 1 3 2 Nausea 1 5 4 Urticaria 3 0 2 Palpitation 28 23 26 Heartburn 11 7 10 Generalized itching 22 30 25 Non respiratory symptoms in asthma as possible predictors of exacerbations Gennaro Liccardi, MD, Gennaro Baldi, MD, Adriano Berra, MD, Emanuela Carpentieri, MD, Marina Cutajar, MD, Maria D’Amato, MD, Mario Del Donno, MD, Bruno Del Prato, MD, Ilenia Folletti, MD, Federica Gani, MD, Domenico Gargano, MD, Domenico Giannattasio, MD, Michele Giovannini, MD, Antonio Infan…

AdultMalemedicine.medical_specialtyAdolescentPrognosiSettore MED/10 - Malattie Dell'Apparato RespiratorioAutonomic Nervous SystemYoung AdultAdolescent; Adult; Aged; Anxiety Disorders; Asthma; Autonomic Nervous System; Child; Cross-Sectional Studies; Disease Progression; Female; Humans; Italy; Male; Middle Aged; Prognosis; Young AdultmedicineImmunology and AllergyHumansPsychiatryChildAgedAdolescent; Adult; Aged; Anxiety Disorders; Asthma; Autonomic Nervous System; Child; Cross-Sectional Studies; Disease Progression; Female; Humans; Italy; Male; Middle Aged; Prognosis; Young Adult; Immunology and Allergy; Medicine (all)Cross-Sectional Studiebusiness.industryMedicine (all)Disease progressionMiddle AgedPrognosisAnxiety DisordersAsthmaCross-Sectional StudiesItalyDisease ProgressionFemalebusinessAnxiety DisorderHuman
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Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria phenotype in patients with splanchnic vein thrombosis

2014

Abstract Introduction Splanchnic vein thrombosis (SVT) is a serious complication in patients with paroxysmal nocturnal hemoglobinuria (PNH). Mutant PNH clones can be associated with an increased risk of SVT even in the absence of overt disease, but their prevalence in non-selected SVT patients remains unknown. Materials and Methods Patients with objective diagnosis of SVT and without known PNH were tested for the presence of PNH clone using high-sensitivity flow cytometric analysis. Results A total of 202 SVT patients were eligible, 58.4% were males, mean age was 54.6 years (range 17–94), site of thrombosis was portal in 103 patients, mesenteric in 67, splenic in 37, and supra-hepatic in 10…

AdultMalemedicine.medical_specialtyCirrhosisAdolescentParoxysmalHemoglobinuria ParoxysmalHemoglobinuriaGastroenterologyYoung AdultRisk Factorshemic and lymphatic diseasesInternal medicine80 and overmedicineHumansMyeloproliferative neoplasmAgedAged 80 and overVenous Thrombosisbusiness.industryMedicine (all)Splanchnic vein thrombosisHematologyMiddle Agedmedicine.diseaseHematopoietic Stem CellsThrombosisAdolescent; Adult; Aged; Aged 80 and over; Cross-Sectional Studies; Female; Hematopoietic Stem Cells; Hemoglobinuria Paroxysmal; Humans; Male; Middle Aged; Risk Factors; Venous Thrombosis; Young Adult; Hematology; Medicine (all)SurgeryPortal vein thrombosisVenous thrombosisSettore MED/15 - MALATTIE DEL SANGUECross-Sectional StudiesSplanchnic vein thrombosisParoxysmal nocturnal hemoglobinuriaFemaleHemoglobinuriabusiness
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Is diabetes in Cushing's syndrome only a consequence of hypercortisolism?

2014

ObjectiveDiabetes mellitus (DM) is one of the most frequent complications of Cushing's syndrome (CS). The aim of this study was to define the changes in insulin sensitivity and/or secretion in relation to glucose tolerance categories in newly diagnosed CS patients.DesignCross-sectional study on 140 patients with CS.MethodsA total of 113 women (80 with pituitary disease and 33 with adrenal disease, aged 41.7±15.7 years) and 27 men (19 with pituitary disease and eight with adrenal disease, aged 38.1±20.01 years) at diagnosis were divided according to glucose tolerance into normal glucose tolerance (CS/NGT), impaired fasting glucose and/or impaired glucose tolerance (CS/prediabetes), and diabe…

AdultMalemedicine.medical_specialtyHydrocortisoneEndocrinology Diabetes and Metabolismmedicine.medical_treatmentCushing's syndromeSettore MED/13 - EndocrinologiaPrediabetic StateImpaired glucose toleranceEndocrinologyInsulin resistanceInternal medicineDiabetes mellitusInsulin SecretionGlucose IntoleranceDiabetes MellitusmedicineHumansInsulinPrediabetesCushing SyndromeRetrospective StudiesCushing DiabetesGlucose tolerance testhypercortisolismmedicine.diagnostic_testbusiness.industryInsulinGeneral MedicineGlucose Tolerance TestMiddle Agedmedicine.diseaseImpaired fasting glucoseDiabetes and MetabolismCross-Sectional StudiesPhenotypeEndocrinologyDiabetes Mellitus Type 2diabeteFemaleInsulin ResistanceMetabolic syndromebusinessAdult; Cross-Sectional Studies; Cushing Syndrome; Diabetes Mellitus Type 2; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male; Middle Aged; Phenotype; Prediabetic State; Retrospective Studies; Endocrinology Diabetes and Metabolism; EndocrinologyType 2European Journal of Endocrinology
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Characterization of patients with mood disorders for their prevalent temperament and level of hopelessness.

2014

Abstract Background Mood disorders (MD) are disabling conditions throughout the world associated with significant psychosocial impairment. Affective temperaments, as well as hopelessness, may play a significant role in the pathophysiology of MD. The present study was designed to characterize patients with MD for their prevalent affective temperament and level of hopelessness. Methods Five hundred fifty-nine (253 men and 306 women) consecutive adult inpatients were assessed using the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionnaire version (TEMPS-A), the Gotland Scale for Male Depression (GSMD), the Beck Hopelessness Scale (BHS) and the Mini International Neurop…

AdultMalemedicine.medical_specialtyHyperthymic temperamentBipolar Disordermedia_common.quotation_subjectpsychologyHopemedicineHumansBipolar disorderTemperamentPsychiatryAgedMini-international neuropsychiatric interviewmedia_commonDepressive DisorderDepressive Disorder MajorAdult Aged Anxiety Disorders; psychology Bipolar Disorder; psychology Cross-Sectional Studies Cyclothymic Disorder; psychology Depressive Disorder; Major; psychology Female Hope Humans Irritable Mood Male Middle Aged TemperamentMajorMiddle Agedmedicine.diseaseAnxiety DisordersCyclothymic DisorderIrritable MoodPsychiatry and Mental healthClinical PsychologyCross-Sectional StudiesMood disordersBeck Hopelessness ScaleMajor depressive disorderAnxietyFemaleTemperamentmedicine.symptomPsychologyClinical psychology
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Prevalence and correlates of QTc prolongation in Italian psychiatric care: cross-sectional multicentre study.

2016

Aims.In recent years several warnings have been issued by regulatory authorities on the risk of electrocardiogram abnormalities in individuals exposed to psychotropic drugs. As a consequence of these warnings, monitoring of the QT interval corrected for heart rate (QTc) has become increasingly common. This study was conducted to measure the frequency of QTc prolongation in unselected psychiatric patients, and to document the associated factors using a cross-sectional approach.Method.The study was carried out in 35 Italian psychiatric services that are part of the STAR (Servizi Territoriali Associati per la Ricerca) Network, a research group established to produce scientific knowledge by col…

AdultMalemedicine.medical_specialtyPsychotropic drugsEpidemiologymedicine.medical_treatmentLong QT syndromeAntidepressantDrug overdoseAdverse effectQT intervalAntipsychotic03 medical and health sciencesElectrocardiography0302 clinical medicineRisk FactorsPsychotropic drugmedicinePrevalenceHumanscardiovascular diseasesAntipsychoticAdverse effectPsychiatrySettore MED/25 - PsichiatriaPolypharmacybusiness.industryEnvironmental and Occupational HealthPublic Health Environmental and Occupational HealthAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Epidemiology; Public Health; Environmental and Occupational Health; Psychiatry and Mental HealthOriginal Articlesmedicine.diseaseAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Epidemiology; Public Health Environmental and Occupational Health; Psychiatry and Mental Health030227 psychiatrySubstance abuseLong QT SyndromeCross-Sectional StudiesItalyPsychiatry and Mental HealthPolypharmacyAripiprazoleFemalePublic HealthbusinessAntidepressant; adverse effect; antipsychotic; psychotropic drugsAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Adult; Antipsychotic Agents; Cross-Sectional Studies; Electrocardiography; Female; Humans; Italy; Long QT Syndrome; Male; Prevalence; Risk Factors; Polypharmacy; Epidemiology; Public Health Environmental and Occupational Health; Psychiatry and Mental Health030217 neurology & neurosurgerymedicine.drugAntipsychotic AgentsEpidemiology and psychiatric sciences
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Selective activation of shoulder, trunk, and arm muscles: A comparative analysis of different push-up variants

2015

Context The push-up is a widely used exercise for upper limb strengthening that can be performed with many variants. A comprehensive analysis of muscle activation during the ascendant phase (AP) and descendant phase (DP) in different variants could be useful for trainers and rehabilitators. Objective To obtain information on the effect of different push-up variants on the electromyography (EMG) of a large sample of upper limb muscles and to investigate the role of the trunk and abdomen muscles during the AP and DP. Design Cross-sectional study. Setting University laboratory. Patients or Other Participants Eight healthy, young volunteers without a history of upper extremity or spine injury.…

AdultMalemedicine.medical_specialtyShoulderPhysical TherapyFitneContext (language use)Physical Therapy Sports Therapy and RehabilitationFitness; Kinesiology; Rehabilitation; Training; Orthopedics and Sports Medicine; Physical Therapy Sports Therapy and RehabilitationElectromyographySports Therapy and RehabilitationPhysical medicine and rehabilitationFitnessmedicineHumansTrainingOrthopedics and Sports MedicineMuscle SkeletalExerciseOriginal ResearchAbdominal MusclesCross-Sectional StudieAnalysis of VarianceSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' SportiveKinesiologymedicine.diagnostic_testbusiness.industryElectromyographyRehabilitationTorsoMuscle activationGeneral MedicineFitness; Kinesiology; Rehabilitation; Training; Abdominal Muscles; Adult; Analysis of Variance; Arm; Cross-Sectional Studies; Electromyography; Exercise; Female; Healthy Volunteers; Humans; Male; Muscle Skeletal; Shoulder; Spine; Torso; Orthopedics and Sports Medicine; Physical Therapy Sports Therapy and RehabilitationTorsoKinesiologyTrunkHealthy VolunteerHealthy VolunteersSpinemedicine.anatomical_structureCross-Sectional StudiesPush-upArmUpper limbAbdominal MuscleFemalebusinessHuman
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Total body skin examination for skin cancer screening in patients with focused complaints

2012

Background. The value of total body skin examination (TBSE) for skin cancer screening is controversial. Objective: We sought to determine whether TBSE could be helpful in patients with focused skin symptoms who would not otherwise have undergone TBSE. Methods: In a prospective, multicenter, cross-sectional study consecutive adult patients were recruited during a period of 18 months. Physicians first inspected, problem areas and uncovered areas and then performed TBSE. Equivocal lesions detected in both steps were excised or biopsied. Primary outcomes were the absolute and relative risks of missing skin cancer and the number of patients needed to examine to detect melanoma or another maligna…

AdultMalemedicine.medical_specialtySkin NeoplasmsBiopsyprevalenceDermoscopyPhysical examinationDermatologydermatoscopyMalignancySkin Diseasesskin cancer; dermoscopy; prevention; prevalencetotal body skin examinationpreventionAdult; Aged; Biopsy; Cross-Sectional Studies; Dermoscopy; Early Detection of Cancer; Female; Humans; Male; Middle Aged; Physical Examination; Prospective Studies; Skin Diseases; Skin NeoplasmsBiopsymedicinemelanomaHumansProspective StudiesProspective cohort studyPhysical ExaminationEarly Detection of CancerAgedCross-Sectional StudieDermatoscopyintegumentary systemmedicine.diagnostic_testskin cancerbusiness.industrySkin DiseaseMelanomascreeningpigmented skin lesionsMiddle Agedmedicine.diseaseDermatologyProspective StudieCross-Sectional Studiestotal body skin examination; melanoma; skin cancer; preventionRelative riskFemalenonmelanoma skin cancerdermoscopySkin cancerbusinessHuman
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Stress in Medical Students: PRIMES, an Italian, Multicenter Cross-Sectional Study

2022

Medical students (MSs) are healthcare workers and must also cope with education-related stressors. This study aims to assess factors associated with perceived stress in Italian MSs. A cross-sectional study was conducted in 12 Italian medical schools (MSCs) in November 2018. A questionnaire assessed socio-demographic characteristics, habits, opinions about MSC, and concerns about the future. Stress was assessed with the PSS-10. Descriptive and univariable tests were performed. A linear model was fitted to find associations of the PSS-10 score with characteristics. There were 2513 collected questionnaires. Median PSS-10 score was 18 (IQR 11). Median age was 22 (IQR 4) and 61% of the sample wa…

AdultStudents MedicalschoolHealth Toxicology and Mutagenesiscross-sectional studiesStressmedicalpsychological distrecross-sectional studies; medical; medical; psychological; psychological distress; schools; stress; studentsYoung Adultpsychological distressstreSurveys and QuestionnairesAdaptation Psychologicalcross-sectional studies; medical; psychological; psychological distress; schools; stress; students; Adaptation Psychological; Adult; Cross-Sectional Studies; Female; Humans; Schools Medical; Stress Psychological; Surveys and Questionnaires; Young Adult; Students MedicalHumansAdaptationSchools MedicalSchoolsstudentscross-sectional studies medical psychological psychological distress schools stress studentsPublic Health Environmental and Occupational Healthpsychological distress; stress; psychological; schools; medical; students; medical; cross-sectional studiescross-sectional studiePsychologicalFemaleStress PsychologicalInternational Journal of Environmental Research and Public Health
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Quality of life following urinary diversion: Orthotopic ileal neobladder versus ileal conduit. A multicentre study among long-term, female bladder ca…

2019

Abstract Introduction Women undergoing radical cystectomy (RC) followed by urinary diversion (UD) for bladder cancer experience a substantial reduction in health-related quality of life (HRQOL). At present, studies comparing long-term QOL outcomes for different UD methods, needed to inform evidence-based choices of bladder reconstruction for female patients, are sparse. Our objective was to compare two common UD methods in terms of their HRQOL outcomes in women. Materials and methods We retrospectively analysed HRQOL in 73 consecutive female bladder cancer patients having undergone orthotopic ileal neobladder (IONB, N = 24) or ileal conduit (IC, N = 49) following RC between 2007 and 2013 in…

Bladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Women;Time Factorsmedicine.medical_treatment030232 urology & nephrologyUrinary DiversionBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Women; Adult; Aged; Aged 80 and over; Cancer Survivors; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Ileum; Italy; Middle Aged; Surveys and Questionnaires; Survival Rate; Time Factors; Urinary Bladder Neoplasms; Urinary Diversion; Quality of Life; Urinary Reservoirs Continent; Surgery; Oncology0302 clinical medicineCancer SurvivorsQuality of lifeSurveys and QuestionnairesOrthotopic neobladder80 and overSurveys and QuestionnaireStage (cooking)Aged 80 and overSettore MED/24 - UROLOGIABladder cancerUrinary Reservoirs ContinentGeneral MedicineMiddle AgedhumanitiesSurvival RateIleal conduitItalyOncology030220 oncology & carcinogenesisUrinary Bladder NeoplasmFemaleCancer SurvivorUrinary ReservoirsHumanQuality of lifeAdultmedicine.medical_specialtyTime FactorFollow-Up StudieCystectomy03 medical and health sciencesIleumInternal medicinemedicineHumansWomenPathologicalAgedCross-Sectional StudieBladder cancerbusiness.industryUrinary diversionCancermedicine.diseaseRadiation therapyRadical cystectomyContinentCross-Sectional StudiesBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; WomenUrinary Bladder NeoplasmsSurgerybusinessFollow-Up StudiesEuropean Journal of Surgical Oncology
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Severe hypoglycemia is associated with antidiabetic oral treatment compared with insulin analogs in nursing home patients with type 2 diabetes and de…

2015

Abstract Objectives Severe hypoglycemia is associated with cognitive decline and dementia in older persons with type 2 diabetes. The role of antidiabetic treatments on severe hypoglycemia is unknown in dementia. The aims were to determine the prevalence of severe hypoglycemic events and investigate associations among severe hypoglycemic and specific antidiabetic treatments (classes of oral agents and types of insulin analogs) in a large sample of nursing home patients with diabetes according to dementia status. Design Cross-sectional observational study. Setting A total of 150 nursing homes across Italy. Participants A total of 2258 patients with type 2 diabetes (dementia = 1138, no dementi…

Blood GlucoseMaleAgingSevere hypoglycemia dementia insulin analogs antidiabetic oral agents agingmedicine.medical_treatmentInsulin analogAdministration OralType 2 diabetesSeverity of Illness IndexInsulin AntagonistsReference ValuesOdds RatioPrevalenceHomes for the AgedInsulinReference ValueCognitive declineNursing (all)2901 Nursing (miscellaneous)General NursingAged 80 and overInsulin AntagonistMedicine (all)Health PolicyAging; Antidiabetic oral agents; Dementia; Insulin analogs; Severe hypoglycemia; Administration Oral; Age Distribution; Aged; Aged 80 and over; Blood Glucose; Confidence Intervals; Cross-Sectional Studies; Dementia; Diabetes Mellitus Type 2; Female; Homes for the Aged; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Antagonists; Italy; Logistic Models; Male; Middle Aged; Nursing Homes; Odds Ratio; Prevalence; Prognosis; Reference Values; Risk Assessment; Severity of Illness Index; Sex Distribution; Sulfonylurea Compounds; Nursing (all)2901 Nursing (miscellaneous); Health PolicyGeneral MedicineMiddle AgedPrognosisSulfonylurea CompoundNursing HomeItalyFemaleHumanmedicine.medical_specialtyLogistic ModelPrognosiHypoglycemiaelderly patientsRisk AssessmentAge DistributionInternal medicineDiabetes mellitusmedicineConfidence IntervalsDementiaHumansHypoglycemic AgentsSex DistributionAgedAntidiabetic oral agentCross-Sectional StudieSevere hypoglycemiaHypoglycemic Agentbusiness.industryInsulinOdds ratiomedicine.diseaseHypoglycemiaNursing HomesEndocrinologyCross-Sectional StudiesLogistic ModelsSulfonylurea CompoundsDiabetes Mellitus Type 2DementiaGeriatrics and GerontologybusinessConfidence IntervalBody mass indexJournal of the American Medical Directors Association
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