Search results for " data"

New dopamine D2 receptor polymorphisms in rats and association with apomorphine-induced stereotypies.

2002

Adult Wistar rats injected with the dopamine receptor agonist apomorphine display different types of motility patterns with respect to oral stereotypes and locomotor activities. It was tested whether phenotypes exhibiting either ‘sniffing’ or ‘non-sniffing’ behaviour differed in gene structures of dopamine receptors D1 or D2. Forty-five Wistar rats of both genders were tested after a single dose of apomorphine (2 mg/kg s.c.) for stereotyped behaviour. Sequence analysis of the 5′ flanking region, the 5′ untranslated region and the coding region of the two genes revealed a new sequence for the 5′ flanking region of the D1 receptor gene and two polymorphisms in the promoter region of the D2 re…

Extracellular Domains of the Bradykinin B2 Receptor Involved in Ligand Binding and Agonist Sensing Defined by Anti-peptide Antibodies

1996

Many of the physiological functions of bradykinin are mediated via the B2 receptor. Little is known about binding sites for bradykinin on the receptor. Therefore, antisera against peptides derived from the putative extracellular domains of the B2 receptor were raised. The antibodies strongly reacted with their corresponding antigens and cross-reacted both with the denatured and the native B2 receptor. Affinity-purified antibodies to the various extracellular domains were used to probe the contact sites between the receptor and its agonist, bradykinin or its antagonist HOE140. Antibodies to extracellular domain 3 (second loop) efficiently interfered, in a concentration-dependent manner, with…

Endothelin receptors mediating contraction in goat cerebral arteries

1993

1. The aim of the present study was to identify the subtype of receptor mediating contraction to endothelin-1 and sarafotoxin S6b in goat isolated middle cerebral arteries. 2. Endothelin-1, endothelin-2 and endothelin-3 contracted cerebral arteries in a concentration-dependent manner. Although the three peptides were full agonists, the order of potency was endothelin-1 = endothelin-2 > endothelin-3, with a relative potency of endothelin-1 and endothelin-2 versus endothelin-3 of approximately 280. Sarafotoxin S6b induced concentration-dependent contractions with lower potency than endothelin-1/endothelin-2, higher potency than endothelin-3 and a higher maximum response than the three endothe…

Altered atypical coupling of γ-aminobutyrate type A receptor agonist and convulsant binding sites in subunit-deficient mouse lines

2001

We searched for subunit correlations for GABA(A) receptor-associated atypically GABA-insensitive [35S]TBPS binding. The homomeric beta3 subunit receptors could be excluded, as GABA-insensitive [35S]TBPS binding was present in beta3-/- mice. Localization of GABA-insensitive [35S]TBPS binding correlated best with those of delta, alpha4 and alpha6 subunit mRNAs. The amounts of GABA-insensitive [35S]TBPS binding components were increased in delta-/- mice, but dramatically reduced in alpha6-/- mice, suggesting a role for alpha6 but excluding delta subunits.

Personality Traits and Foreign Policy Attitudes in German Public Opinion

2007

This article examines the effects of personality traits on attitudes toward foreign policy issues among the German public. Building on previous research, it argues that personality characteristics shape an individual's motivation, goals, and values, thereby providing criteria to evaluate external stimuli and affecting foreign policy opinions. An analysis of survey data from a random sample of Germans eligible to vote confirms that the personality traits play a role in attitudes toward foreign policy issues. By and large, personality affects foreign policy opinions roughly as strongly as traditional factors such as partisanship, ideology, and social background. Among the traits studied, agr…

Can personality predict retirement behaviour? A longitudinal analysis combining survey and register data from Norway.

2017

Published version of an article in the journal: European Journal of Ageing. Also available from the publisher at: http://dx.doi.org/10.1007/s10433-011-0212-6 This study investigates how far personality can predict the timing and routes of people’s retirement. It uses a large comprehensive Norwegian survey, with larger sample size than earlier related studies, providing estimates of personality based on the five-factor model. The survey data are matched with administrative data, allowing observations of retirement over the 2002–2007 period. The analysis distinguishes between the disability and the non-disability retirements. Retirement is investigated using discrete time, competing risk, log…

Prevalence and genetic diversity of Aichi virus strains in stool samples from community and hospitalized patients.

2008

ABSTRACT Aichi virus has been proposed as a causative agent of gastroenteritis. A total of 457 stool specimens from children hospitalized with acute diarrhea and 566 stool specimens from adults and children involved in 110 gastroenteritis outbreaks were screened for the presence of Aichi virus by reverse transcription-PCR (RT-PCR) amplification of the genomic region of the 3C and 3D (3CD) nonstructural proteins. Our results show a low incidence of Aichi virus in pediatric samples and the existence of mixed infections with other microbiological agents in some cases. From the outbreak survey, it appears that the presence of Aichi virus is an indicator of mixed infections causing gastroenterit…

Gestión tradicional de la escorrentía de tormentas para riego de prados en Monteagudo del Castillo (Teruel)

2021

espanolMonteagudo del Castillo (Teruel) esta cerca del polo de maxima tormentosidad violenta de la Peninsula Iberica. El aporte pluviometrico de estas tormentas es capaz de invertir el regimen estacional habitual del clima mediterraneo, con el verano como estacion mas lluviosa. Aqui se estudia la gestion tradicional de la arroyada en dos cuencas del termino municipal, desde la doble perspectiva riesgo/recurso: control de la erosion y aprovechamiento de la arroyada para regar prados. Para gestionar la arroyada concentrada de las tormentas se ha modificado la red de drenaje mediante acequias recolectoras y/o evacuadoras y la rectificacion de la red hidrografica natural. Las acequias de deriva…

Possible role of polycyclic aromatic hydrocarbons in the onset of melanoma: preliminary data.

2019

A new preprocessing tool of ECMWF data for CALMET forecasting simulations

2019

Today, strategies for emergency preparedness, in presence of accidental scenarios in high-risk plants with releases into the atmosphere, have become a priority. To achieve this goal, it is important to have forecast meteorological data in local areas to use in dispersion and transport models and so to respond in advance emergency situations. The paper reports results of research performed to develop a new tool, called FORCALM that is capable to elaborate European Centre for Medium-Range Forecasts (ECMWF) forecast data to use for simulations by CALMET/CALPUFF modeling system. A case study, relevant to an accident occurred in Mediterranean Refinery at Milazzo (Italy), has been examined to val…