Search results for " data"
showing 10 items of 7516 documents
The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase of Candida albicans is a surface antigen.
1997
A lambda gt11 cDNA library from Candida albicans ATCC 26555 was screened by using pooled sera from two patients with systemic candidiasis and five neutropenic patients with high levels of anti-C. albicans immunoglobulin M antibodies. Seven clones were isolated from 60,000 recombinant phages. The most reactive one contained a 0.9-kb cDNA encoding a polypeptide immunoreactive only with sera from patients with systemic candidiasis. The whole gene was isolated from a genomic library by using the cDNA as a probe. The nucleotide sequence of the coding region showed homology (78 to 79%) to the Saccharomyces cerevisiae TDH1 to TDH3 genes coding for glyceraldehyde-3-phosphate dehydrogenase (GAPDH), …
Cloning and characterization of PRA1, a gene encoding a novel pH-regulated antigen of Candida albicans.
1998
ABSTRACT Candida albicans is an opportunistic fungal pathogen of humans. The cell wall of the organism defines the interface between the pathogen and host tissues and is likely to play an essential and pivotal role in the host-pathogen interaction. The components of the cell wall critical to this interaction are undefined. Immunoscreening of a lambda expression library with sera raised against mycelial cell walls of C. albicans was used to identify genes encoding cell surface proteins. One of the positive clones represented a candidal gene that was differentially expressed in response to changes in the pH of the culture medium. Maximal expression occurred at neutral pH, with no expression d…
Identification of a mannoprotein present in the inner layer of the cell wall of Saccharomyces cerevisiae.
1997
Cell wall extracts from the double-mutant mnn1 mnn9 strain were used as the immunogen to obtain a monoclonal antibody (MAb), SAC A6, that recognizes a specific mannoprotein--which we have named Icwp--in the walls of cells of Saccharomyces cerevisiae. Icwp runs as a polydisperse band of over 180 kDa in sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of Zymolyase extracts of cell walls, although an analysis of the secretory pattern of the mannoprotein shows that at the level of secretory vesicles, it behaves like a discrete band of 140 kDa. Immunofluorescence analysis with the MAb showed that Icwp lies at the inner layer of the cell wall, being accessible to the antibody on…
Internet Related Technologies in the auditing profession: A WOS bibliometric review of the past three decades and conceptual structure mapping
2022
Research on Internet-Related Technologies in the auditing profession has grown substantially over the past three decades; however, it is very fragmented. This study seeks to synthesize and provide a comprehensive overview of the literature. Using bibliometric techniques and content analysis, this study provides an exhaustive overview of the research on Internet-Related Technologies in the auditing profession. The study utilized bibliography from the Web of Science database spanning for three decades from 1990 to 2019. A total of 236 academic documents, written by 478 authors from 102 sources was retrieved and used for the analysis. HistCite and Biblioshiny in R were used to run the citation…
El proyecto mapa escolar de Valencia: Análisis de la zonificación educativa de la ciudad de Valencia
2018
The research project Mapa Escolar de Valencia (School Map of Valencia) was born out of an agreement between the City Council and the University of Valencia in order to carry out an investigation of the compulsory education system of the city and propose, if necessary, modifications to the current school zoning. The project is structured in several research areas. An analysis of the specialized scientific literature and public policies concerning education and schooling has been done, and it is currently analysing the evolution of quantitative and qualitative data on compulsory schooling in Valencia, its school zoning, the representations of education and the school climate in the city schoo…
On the severity of aortic stenosis in ascending aortic aneurysm: A computational tool to examine ventricular-arterial interaction and aortic wall str…
2020
Abstract An ascending thoracic aortic aneurysm (ATAA) is a life-threatening cardiovascular consequence of vessel dilatation that portends adverse events and death. From a clinical perspective, ATAA should not be treated as an isolated disease, and surgery is often carried out in the presence of AS, aortic insufficiency or a calcified valve leaflet. Aortic stenosis (AS) is common in ATAAs and leads to both vessel rigidity and left ventricular (LV) impairment. In this study, lumped-parameter modeling and computational analysis were used to assess the change in the wall shear stress (WSS) and intramural wall stress of patient-specific ATAA models with different degrees of AS (i.e., mild to sev…
Large-scale gene discovery in the pea aphid Acyrthosiphon pisum (Hemiptera)
2006
A large-scale sequencing analysis of the Hemiptera Acyrthosiphon pisumexpressed sequence tags corresponding to about 12,000 unique transcripts is described, along with an in silico profiling analysis that identifies 135 aphid tissue-specific transcripts.
New records of corticioid fungi from Sicily
2016
This paper is the result of an on-going study on distribution and ecology of corticioid wood-inhabiting fungi in Sicily. Twenty-five species not previously recorded in Sicily are here listed. For each taxon, ecological and distributional data are provided. Subulicystidium perlongisporum was recorded in Italy for the first time in two localities occurring on Quercus ilex L. wood. Description, distributional and ecological data of this rare taxon are also provided. Dendrophora versiformis and Kavinia alboviridis, considered rare species in Italy and Europe, are included in this report.
Genetic polymorphisms affecting the phenotypic expression in familial hypercholesterolemia
2004
The clinical expression of heterozygous familial hypercholesterolemia (FH) is highly variable even in patients carrying the same LDL receptor (LDL-R) gene mutation. This variability might be due to environmental factors as well as to modifying genes affecting lipoprotein metabolism. We investigated Apo E (2, 3, 4), MTP (-493G/T), Apo B (-516C/T), Apo A-V (-1131T/C), HL (-514C/T and -250G/A), FABP-2 (A54T), LPL (D9N, N291S, S447X) and ABCA1 (R219K) polymorphisms in 221 unrelated FH index cases and 349 FH relatives with defined LDL-R gene mutations. We found a significant and independent effect of the following polymorphisms on: (i) plasma LDL-C (Apo E, MTP and Apo B); (ii) plasma HDL-C (HL, …
Mappings of finite distortion : size of the branch set
2018
Abstract We study the branch set of a mapping between subsets of ℝ n {\mathbb{R}^{n}} , i.e., the set where a given mapping is not defining a local homeomorphism. We construct several sharp examples showing that the branch set or its image can have positive measure.