Search results for " dental"

showing 10 items of 516 documents

Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells

2017

Human dental pulp stem cells (hDPSCs) are a source for cell therapy. Before implantation, an in vitro expansion step is necessary, with the inconvenience that hDPSCs undergo senescence following a certain number of passages, loosing their stemness properties. Long-term in vitro culture of hDPSCs at 21% (ambient oxygen tension) compared with 3–6% oxygen tension (physiological oxygen tension) caused an oxidative stress-related premature senescence, as evidenced by increased β-galactosidase activity and increased lysil oxidase expression, which is mediated by p16INK4a pathway. Furthermore, hDPSCs cultured at 21% oxygen tension underwent a downregulation of OCT4, SOX2, KLF4 and c-MYC factors, w…

AdultMale0301 basic medicineSenescenceAginghDPSCs human dental pulp stem cellsMSC mesenchymal stem cellsAdolescentCellular differentiationClinical BiochemistryCell Culture TechniquesOSKM OCT4 SOX2 KLF4 and c-MYCBiologymedicine.disease_causeBiochemistryCell therapyKruppel-Like Factor 4Young Adult03 medical and health sciencesDental pulp stem cellsmedicineHumansOxygen tensionlcsh:QH301-705.5SIPS stress-induced premature senescenceCells CulturedCellular SenescenceCyclin-Dependent Kinase Inhibitor p16Dental PulpMDA malondialdehydePolycomb Repressive Complex 1lcsh:R5-920Stem CellsOrganic ChemistryCell DifferentiationOxygen tensionCell biologyOxygenOxidative Stress030104 developmental biologylcsh:Biology (General)Cell cultureRegenerative medicineImmunologyFemaleStem celllcsh:Medicine (General)Oxidative stressResearch PaperRedox Biology
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A method of measuring the apical base

1996

SUMMARY The maxillary and mandibular apical base areas were measured, using a gnathograph, on the study casts of 156 adults and children representing Class II division 1, Class II division 2 and Class III malocclusions. There were significant differences between the groups at each age. The maxillary apical base areas tended to be smaller for the adults than for the children in all three occlusal classes. By contrast, the mandibular apical base areas tended to be larger for the adults than for the children, except in Class II division 1 malocclusion. Following a logarithmic transformation to stabilize the variance, regression lines were fitted to relate the size of the maxillary and mandibul…

AdultMaleAdolescentCephalometryDentistryOrthodonticsMandibleClass iiiMalocclusion Angle Class IIBiologyDental ArchTooth ApexAlveolar ProcessMaxillamedicineHumansClass II division 1 malocclusionChildBase (exponentiation)Analysis of Variancebusiness.industryAge FactorsMandiblemedicine.diseaseModels DentalMalocclusion Angle Class IIIMaxillaLinear ModelsRegression AnalysisFemaleMalocclusionbusinessThe European Journal of Orthodontics
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Oral health-related quality of life in orthodontics: a cross-sectional multicentre study on patients in orthodontic treatment

2019

Summary Objective This study aimed to assess oral health-related quality of life (OHRQoL) in relation to associated covariates in orthodontic patients of different age groups (children, adolescents, and adults) in a cross-sectional study. Methods A total of 898 subjects (50.6% females, 49.4% males; mean age 16.89 years) undergoing orthodontic treatment anonymously completed the German version of the Oral Health Impact Profile (OHIP-G14) to assess OHRQoL in addition to completing 23 other items. Descriptive, exploratory statistical analysis and multiple linear regression modelling were performed. Results The mean score of the OHIP-G14 was 8.3 for the 6- to 11-year olds, 8.9 for the 12- to 17…

AdultMaleAdolescentCross-sectional studyDentistryOral HealthOrthodonticsEsthetics DentalOral health03 medical and health sciences0302 clinical medicineAge groupsQuality of lifeSurveys and QuestionnairesAdolescent groupHumansMedicineStatistical analysis030212 general & internal medicineChildbusiness.industryMean age030206 dentistryhumanitiesCross-Sectional StudiesMulticenter studyQuality of LifeFemalebusinessEuropean Journal of Orthodontics
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Dental aesthetics, self-awareness, and oral health-related quality of life in young adults.

2004

The aim of the present study was to explore the putative relationship between dental aesthetics and oral health-related quality of life (OHRQoL), taking into consideration the potential direct and moderating influence of private and public self-consciousness. The subjects of this cross-sectional survey were 148 university students. Dental aesthetics were assessed by means of the aesthetic component (AC) of the Index of Orthodontic Treatment Need (IOTN). OHRQoL was estimated using a modification of the scales 'social appearance concern' and 'appearance disapproval', and a novel dental self-confidence scale. In addition, the private and public self-consciousness scales were used. Two-factor a…

AdultMaleAdolescentCross-sectional studySelf-conceptDentistryOrthodonticsOral healthEsthetics DentalQuality of life (healthcare)HumansYoung adultAnalysis of VarianceChi-Square Distributionbusiness.industrySelf ConceptCross-Sectional StudiesDental aestheticsScale (social sciences)Self-awarenessQuality of LifeFemalebusinessPsychologyMalocclusionClinical psychologyEuropean journal of orthodontics
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Dental esthetics, orthodontic treatment, and oral-health attitudes in young adults.

2005

Introduction: The aim of this study was to investigate whether young adults with varying dental esthetics and histories of orthodontic treatment also differ in oral-health attitudes, preventive behaviors, and self-perceived oral health. Methods: The sample comprised 298 young adults, 18 to 30 years old, with at least 13 years of primary and secondary school education. The subjects were asked to complete questionnaires dealing with various measures related to oral-health attitudes, preventive behaviors, and perceptions of oral health. Dental esthetics were assessed by means of the aesthetic component of the index of orthodontic treatment need. Dental plaque accumulation was assessed in a sub…

AdultMaleAdolescentSelf-conceptDentistryOrthodonticsOral HealthOral healthEsthetics DentalDental plaqueOral hygieneOrthodontics CorrectivePreventive Health ServicesmedicineHumansYoung adultInternal-External ControlDental estheticsAnalysis of Variancebusiness.industryAwarenessmedicine.diseaseOral HygieneSelf ConceptClinical trialstomatognathic diseasesFemaleMalocclusionbusinessAttitude to HealthMalocclusionAmerican journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
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Development of a questionnaire for assessment of the psychosocial impact of dental aesthetics in young adults

2006

The aim of this study was to develop a psychometric instrument for assessment of orthodontic-specific aspects of quality of life. The study subjects, 194 young adults aged 18-30 years, were interviewed using a pool of 23 items dealing with the psychosocial impact of dental aesthetics. Self- and interviewer-rating of the dental aesthetic appearance of each subject were carried out using the Aesthetic Component (AC) of the Index of Orthodontic Treatment Need (IOTN). Additionally, the Perception of Occlusion Scale and a modification of the Dental Aesthetic Index (DAI) were applied. Factorial analyses identified four measures within the item pool, namely Dental Self-Confidence, Social Impact, P…

AdultMaleAdolescentSelf-conceptValidityDentistryOrthodonticsEsthetics DentalInterpersonal relationshipSocial DesirabilityQuality of lifeSurveys and QuestionnairesmedicineHumansInterpersonal RelationsYoung adultbusiness.industryReproducibility of Resultsmedicine.diseaseSelf ConceptScale (social sciences)Quality of LifeFemaleMalocclusionPsychologybusinessAttitude to HealthSocial AdjustmentPsychosocialMalocclusionClinical psychology
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Differences in psychological traits between lingual and labial orthodontic patients: perfectionism, body image, and the impact of dental esthetics.

2014

OBJECTIVE: To examine some of the patients' psychological traits in relation to their levels of perfectionism and their body image, and to discover whether these differ between lingual and labial orthodontic patients. MATERIALS AND METHODS: A cross-sectional study was designed with a consecutive sample of 80 patients attending a private orthodontic office. Three questionnaires were used to assess the patients' body image and level of perfectionism. The mean age was 33 years. The men numbered 32 and the women 48. The validated Spanish version of the Psychosocial Impact of Dental Aesthetic Questionnaire (PIDAQ) was used to assess the psychosocial impact of their dental esthetics. The Multidim…

AdultMaleAdolescentTooth Movement TechniquesOrthodontic BracketsOrthodonticsPilot ProjectsEsthetics Dentalmedicine.disease_causeCONSECUTIVE SAMPLEYoung Adultstomatognathic systemmedicineBody ImageHumansOrthodontic Appliance DesignParent-Child RelationsDental estheticsAge FactorsSpanish versionMean ageMultidimensional perfectionismPerfectionism (psychology)Original ArticlesMiddle AgedConfidence intervalSelf Conceptstomatognathic diseasesCross-Sectional StudiesSocial ClassFemalePsychologyPsychosocialAttitude to HealthClinical psychologyPersonalityThe Angle orthodontist
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The important impact of dental care on haemostatic treatment burden in patients with mild haemophilia

2022

Background: Mild haemophilia (MH) is mainly characterized by haemorrhages secondary to surgery/invasive procedures or trauma. Haemostatic treatment in MH ranges from on demand to short prophylaxis according to the type of bleeding events and the basal clotting factor level. Oral surgery and dental extractions can represent a frequent haemostatic challenge in MH requiring appropriate treatment. However, only few studies on limited numbers of patients are available in the literature regarding the implications of dental management in patients with MH. Objectives: The purpose of the study was to evaluate the impact of dental care on the burden of haemostatic treatment in patients affected by MH…

AdultMaleAged 80 and overFactor VIIIAdolescentHemorrhageHematologyGeneral MedicineMiddle AgedHemophilia Amild haemophilia dental care FVIII FIX haemophilia treatmentHemostaticsAntifibrinolytic AgentsBlood Coagulation FactorsYoung AdultHumansDental CareGenetics (clinical)Aged
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Mandibular connective tissue pedicle flaps in implant dentistry: report of three cases.

2007

Abstract An increase in soft tissues and alveolar bone in the anterior mandibular area between the canines is necessary to achieve a good esthetic result. The present article describes a technique for gaining bone volume and soft tissue to cover bone defects that would otherwise compromise the final result of prosthetic implant restoration in the anterior mandible. Three patients with anterior mandibular atrophy caused by loss of the mandibular incisors are presented. Particulate autologous bone grafting, the raising of a pediculate connective tissue flap to increase soft tissue, and implant placement were carried out simultaneously. After 2 years of follow-up, the implants were in good cli…

AdultMaleAlveolar Bone LossGingivaDentistryConnective tissueMandibleEsthetics DentalTransplantation AutologousSurgical FlapsAtrophyOsseointegrationmedicineHumansDental alveolusOrthodonticsDental ImplantsBone TransplantationImplant dentistrybusiness.industryMandibleSoft tissueAlveolar Ridge AugmentationMiddle Agedmedicine.diseaseIncisormedicine.anatomical_structureConnective TissueFemaleImplantOral SurgeryAtrophybusinessBone volumeFollow-Up StudiesThe Journal of oral implantology
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Determination of Bolton tooth-size ratios by digitization, and comparison with the traditional method.

2005

The Bolton Index is one of the most useful calculations for precise orthodontic diagnosis as it shows if there is a correct ratio between dental proportions. However, at times, this calculation is not applied because it is a long and time-consuming procedure compared with digital methods. A new digital method for measuring tooth sizes and for calculating the Anterior (ABI) and the Overall (OBI) Bolton Index was tested on 100 sets of study dental casts of the permanent dentition in a Spanish sample and compared with the traditional method. The reproducibility of this digital method versus the traditional one was analysed to determine intra- and inter-examiner measurement errors by calculatin…

AdultMaleCuspidAdolescentPermanent dentitionDentistryOrthodonticsStatisticsImage Processing Computer-AssistedMedicineHumansOdontometryBicuspidTOOTH SIZEChildDigitizationObserver VariationReproducibilityPermanent toothObservational errorbusiness.industryReproducibility of ResultsMolarRegressionModels DentalIncisorFemalebusinessToothEuropean journal of orthodontics
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