Search results for " device"

showing 10 items of 1082 documents

Effects of medially posted insoles on foot and lower limb mechanics across walking and running in overpronating men.

2017

Anti-pronation orthoses, like medially posted insoles (MPI), have traditionally been used to treat various of lower limb problems. Yet, we know surprisingly little about their effects on overall foot motion and lower limb mechanics across walking and running, which represent highly different loading conditions. To address this issue, multi-segment foot and lower limb mechanics was examined among 11 over-pronating men with normal (NORM) and MPI insoles during walking (self-selected speed 1.70 +/- 0.19 m/s vs 1.72 +/- 0.20 m/s, respectively) and running (4.04 +/- 0.17 m/s vs 4.10 +/- 0.13 m/s, respectively). The kinematic results showed that MPI reduced the peak forefoot eversion movement in …

MaleMOTIONKnee JointOrthoticsKinematicsWalkingORTHOTICSRunning0302 clinical medicineMOMENTSOrthopedics and Sports Medicineta315Rehabilitationmulti-segment foot kinematicsBiomechanicsta3141MechanicsBiomechanical Phenomenamedicine.anatomical_structureKNEEmedicine.medical_specialtyOrthotic DevicesMovementBiomedical EngineeringBiophysicspronationmedially posted insolesjuoksuwalking03 medical and health sciencesmedicinePressureHumansPronationTibiaKINEMATICSTibiabusiness.industryFootForefootANKLE030229 sport sciences217 Medical engineeringORTHOSESBIOMECHANICSbody regionsKineticskineticsREARFOOTCoronal planeAnklebusinesshuman activities030217 neurology & neurosurgeryAnkle JointCenter of pressure (fluid mechanics)Journal of biomechanics
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Quantitative assessment and localization of the hollowing of the temple after craniectomy and cranioplasty–The frontozygomatic shadow

2021

Background After cranioplasty, in many cases a not negligible soft tissue defect remains in the temporozygomatical area, also referred to as a hollowing defect of the temple. Objective To assess the precise localization and volume of the hollowing defect, to optimize future cranioplasties. Methods CT data of patients who received craniectomy and conventional CAD cranioplasty in our institution between 2012 and 2018 were analyzed. CT datasets prior to craniectomy and after cranioplasty were subtracted to quantify the volume and localization of the defect. Results Out of 91 patients, 21 had suitable datasets. Five cases had good cosmetic results with no defect visible, 16 patients had an app…

MaleMedical Implantsmedicine.medical_treatmentHealth Care ProvidersComputed tomographyNervous System ProceduresQuantitative assessmentMedicine and Health SciencesMedical PersonnelMusculoskeletal SystemMultidisciplinarymedicine.diagnostic_testQRSoft tissueMiddle AgedBuilt StructuresCranioplastyProfessionsmedicine.anatomical_structureTreatment OutcomeMedicineSuperior temporal lineEngineering and TechnologyFemaleAnatomyPlastic Surgery and Reconstructive TechniquesResearch ArticleBiotechnologyAdultmedicine.medical_specialtyDecompressive CraniectomyStructural EngineeringSoft TissuesScienceSurgical and Invasive Medical ProceduresBioengineeringTemporal MuscleZygomatic processTemporal muscleCranioplastyTime-to-TreatmentPhysiciansmedicineHumansSkeletonAgedRetrospective StudiesSurgeonsbusiness.industrySkullBiology and Life SciencesPlastic Surgery ProceduresSurgeryHealth CareSkullBiological TissuePeople and PlacesMedical Devices and EquipmentPopulation GroupingsbusinessTomography X-Ray ComputedHeadPLoS ONE
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Medial buttressing of the quadrilateral surface in acetabular and periprosthetic acetabular fractures

2020

Background In geriatric acetabular fractures, the quadrilateral plate is often involved in the fracture pattern and medially displaced. Open reduction and internal fixation (ORIF) includes reduction of the quadrilateral plate and securing its position. In this study, the concept of medial buttressing in acute and periprosthetic acetabular fractures is evaluated. Materials and methods Patients, who sustained an acetabular fracture between 2012 and 2018, in whom ORIF with a specific implant for medial buttressing was performed, were included in the study. Patients were divided in two groups; acute acetabular fractures (group 1) and periprosthetic acetabular fractures (group 2). Demographics,…

MaleMedical Implantsmedicine.medical_treatmentPeriprostheticTotal Hip ArthroplastyTOTAL HIP-ARTHROPLASTYFractures BonePostoperative ComplicationsINTERNAL-FIXATIONQuality of lifeSkeletal JointsQUALITY-OF-LIFEMedicine and Health SciencesMedicineMusculoskeletal SystemELDERLY-PATIENTSOPEN REDUCTIONPOPULATIONGeriatricsAged 80 and overMultidisciplinaryQRAcetabular fractureMiddle AgedHospitalsHospitalizationMultidisciplinary SciencesMedicineEngineering and TechnologyScience & Technology - Other TopicsFemaleAnatomyTotal hip arthroplastyResearch ArticleBiotechnologymedicine.medical_specialtyScienceSurgical and Invasive Medical ProceduresBioengineeringCLASSIFICATIONArthroplastyPelvisMusculoskeletal System ProceduresMANAGEMENTInternal fixationHumansReduction (orthopedic surgery)SkeletonAgedRetrospective StudiesHipScience & Technologybusiness.industryBiology and Life SciencesAcetabulummedicine.diseaseSurgeryHealth CareGeriatricsHealth Care FacilitiesQuality of LifeMedical Devices and EquipmentImplantbusiness
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Pre-Infarction Angina and Outcomes in Non-ST-Segment Elevation Myocardial Infarction: Data from the RICO Survey

2012

BACKGROUND: The presence of pre-infarction angina (PIA) has been shown to confer cardioprotection after ST-segment elevation myocardial infarction (STEMI). However, the clinical impact of PIA in non-ST-segment elevation myocardial infarction (NSTEMI) remains to be determined. METHODS AND RESULTS: From the obseRvatoire des Infarctus de Côte d'Or (RICO) survey, 1541 consecutive patients admitted in intensive care unit with a first NSTEMI were included. Patients who experienced chest pain <7 days before the episode leading to admission were defined as having PIA and were compared with patients without PIA. Incidence of in-hospital ventricular arrhythmias (VAs), heart failure and 30-day mortali…

MaleNon-Clinical MedicineMyocardial Infarctionlcsh:MedicineInfarctionCoronary AngiographyCardiovascularChest painAnginaIschemiaST segmentProspective StudiesMyocardial infarctionlcsh:ScienceMultidisciplinaryData CollectionClinical PharmacologyMiddle AgedAnginaPrognosisTreatment OutcomeCardiologyMedicineFemaleFrancemedicine.symptomResearch ArticleDrugs and Devicesmedicine.medical_specialtyCritical CareCardiologyHealth InformaticsCardiovascular PharmacologyAngina PectorisIntensive careInternal medicinemedicineHumansAgedHealth Care Policybusiness.industrylcsh:RArrhythmias Cardiacmedicine.diseaseHealth SurveysHeart failureMultivariate AnalysisMyocardial infarction complicationslcsh:QHealth StatisticsbusinessPLoS ONE
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What users think about the differences between caffeine and illicit/prescription stimulants for cognitive enhancement

2012

Pharmacological cognitive enhancement (CE) is a topic of increasing public awareness. In the scientific literature on student use of CE as a study aid for academic performance enhancement, there are high prevalence rates regarding the use of caffeinated substances (coffee, caffeinated drinks, caffeine tablets) but remarkably lower prevalence rates regarding the use of illicit/prescription stimulants such as amphetamines or methylphenidate. While the literature considers the reasons and mechanisms for these different prevalence rates from a theoretical standpoint, it lacks empirical data to account for healthy students who use both, caffeine and illicit/prescription stimulants, exclusively f…

MaleNon-Clinical MedicinePsychopharmacologymedicine.medical_treatment610 Medizinlcsh:MedicineScientific literatureMedical LawSocial and Behavioral SciencesDrug UsersCognition610 Medical sciencesMedical SociologyHuman PerformancePsychologylcsh:ScienceNootropic AgentsProblem Solvingmedia_commonPsychiatryMultidisciplinarySubstance AbuseQualitative StudiesSubstance abuseMental HealthNeurologyHealth Education and AwarenessMedicineFemalePublic HealthBehavioral and Social Aspects of HealthResearch ArticleAdultMedical Ethicsmedicine.medical_specialtyDrugs and DevicesPrescription DrugsUniversitiesSubstance-Related DisordersClinical Research DesignScience Policymedia_common.quotation_subjectCognitive NeuroscienceDecision MakingNeuropharmacologyNeuropsychologyCaffeinemedicineHumansMedical prescriptionStudentsPsychiatryBiologyBehaviorHealth Care Policybusiness.industryIllicit DrugsAddictionlcsh:RCognitive PsychologyBioethicsmedicine.diseaseStimulantScience Educationlcsh:QCentral Nervous System StimulantsCitationAttributionbusinessLawMedical ethicsNeuroscience
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Role of Kras Status in Patients with Metastatic Colorectal Cancer Receiving First-Line Chemotherapy plus Bevacizumab: A TTD Group Cooperative Study

2012

Background: In the MACRO study, patients with metastatic colorectal cancer (mCRC) were randomised to first-line treatment with 6 cycles of capecitabine and oxaliplatin (XELOX) plus bevacizumab followed by either single-agent bevacizumab or XELOX plus bevacizumab until disease progression. An additional retrospective analysis was performed to define the prognostic value of tumour KRAS status on progression-free survival (PFS), overall survival (OS) and response rates. Methodology/Principal Findings: KRAS data (tumour KRAS status and type of mutation) were collected by questionnaire from participating centres that performed KRAS analyses. These data were then cross-referenced with efficacy da…

MaleOncologyOrganoplatinum Compoundsendocrine system diseasesEpidemiologyColorectal cancer:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]DeoxycytidineMetastasis:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Antineoplastic Combined Chemotherapy ProtocolsPathologyMedicineNeoplasm Metastasisgeneslcsh:Sciencemediana edad:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols::Antineoplastic Protocols::Antineoplastic Combined Chemotherapy Protocols [Medical Subject Headings]Aged 80 and overanciano:Chemicals and Drugs::Organic Chemicals::Organometallic Compounds::Organoplatinum Compounds [Medical Subject Headings]Cancer Risk FactorsClinical Pharmacologyprotocolos de quimioterapia antineoplásica combinadaColon AdenocarcinomaPronósticoCombination chemotherapyadultoPrognosisBevacizumabOxaliplatinpronósticoOncologyMedicineOncology Agentsmedicine.medical_specialty:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation [Medical Subject Headings]FluorouraciloBevacizumab:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Pyrimidines::Pyrimidine Nucleosides::Cytidine::Deoxycytidine [Medical Subject Headings]:Check Tags::Male [Medical Subject Headings]Molecular GeneticsCapecitabine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies Monoclonal::Antibodies Monoclonal Humanized [Medical Subject Headings]Gastrointestinal TumorsGenetics:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]HumansClinical TrialsBiologyneoplasmsCapecitabineAgedlcsh:R:Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes Neoplasm::Oncogenes::Proto-Oncogenes::Genes ras [Medical Subject Headings]medicine.diseasedigestive system diseasesOxaliplatin:Check Tags::Female [Medical Subject Headings]PharmacogeneticsMutationlcsh:QfluorouraciloMultivariate analysisDesoxicitidinahumanosCancer Treatment:Named Groups::Persons::Age Groups::Adult::Aged::Aged 80 and over [Medical Subject Headings]lcsh:Medicinemedicine.disease_causeNeoplasias colorrectalesSurgical oncologyBasic Cancer Research:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Pyrimidines::Pyrimidinones::Uracil::Fluorouracil [Medical Subject Headings]Clinical Trials (Cancer Treatment)metástasis neoplásicaMetástasis neoplásicaMultidisciplinaryMiddle AgedGenetic EpidemiologyProtocolos de quimioterapia antineoplásica combinadaFemaleAntiangiogenesis TherapyFluorouracilKRASColorectal NeoplasmsResearch Articlemedicine.drugAdultDrugs and DevicesClinical Pathologyneoplasias colorrectalesClinical Research DesignGenetic Causes of CancerAntibodies Monoclonal HumanizedAntibodiesRectal CancerAntibody TherapyDiagnostic MedicineInternal medicine:Diseases::Neoplasms::Neoplastic Processes::Neoplasm Metastasis [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings]mutaciónClinical GeneticsMutaciónbusiness.industryPharmacoepidemiologyCancers and NeoplasmsHuman GeneticsChemotherapy and Drug TreatmentdesoxicitidinaGenes rasanticuerposGenetics of Diseasebusinesscompuestos organoplatinoPLoS ONE
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Problem-based learning for anesthesia resident operating room crisis management training.

2018

Background Senior anesthesia residents must acquire competency in crisis management for operating room (OR) emergencies. We conducted problem based learning (PBL) OR emergency scenarios for anesthesia residents, focused on emergencies in ‘Airway’, ‘Circulation’, ‘Central venous catheter’, and ‘Pain management complications’. Non-technical skills are an integral component of team-based OR emergency management. Methods Prior to integrated OR emergency clinical and non-technical skills PBL training, participating 35 anesthesia residents completed two 5-point scale surveys regarding frequency of emergency experiences in the operating room, and self-confidence for anesthesia-related crisis manag…

MaleOperating RoomsCritical Care and Emergency Medicinemedicine.medical_treatmentSocial SciencesCrew resource managementlcsh:MedicineCrisis managementLearning and Memory0302 clinical medicineAnesthesiology030202 anesthesiologyMedicine and Health SciencesCardiac ArrestPsychologyIntubationAnesthesia030212 general & internal medicinelcsh:ScienceMultidisciplinaryEmergency managementPharmaceuticsSimulation and ModelingProblem-based learningScale (social sciences)AnesthesiaEngineering and TechnologyFemaleClinical CompetenceCentral venous catheterResearch ArticleBiotechnologyCatheterseducationCardiologyBioengineeringSurgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesDrug TherapymedicineLearningPain ManagementHumansbusiness.industryCrew Resource Management Healthcarelcsh:RCognitive PsychologyBiology and Life SciencesInternship and ResidencyProblem-Based LearningSelf ConceptCognitive ScienceMedical Devices and Equipmentlcsh:QIntubationbusinessAirwayNeurosciencePLoS ONE
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Particle image velocimetry study of the celiac trunk hemodynamic induced by continuous-flow left ventricular assist device

2017

Abstract Whereas left ventricular assist device (LVAD) is the gold-standard therapy for patients with heart failure, gastrointestinal bleeding is one of the most common complications. LVAD implantation may remarkably impact aortic hemodynamics so that experimental and computational flow analyses can be used to study the disease mechanisms. Here we present an experimentally-calibrated computational model of the celiac trunk hemodynamic of a LVAD-supported patient who experienced bleeding after device implantation. Specifically, both particle image velocimetry (PIV) and echocardiography were used to measure and compare flow distributions in each branch of a phantom model of the patient abdomi…

MalePatient-Specific ModelingCardiac outputLeft ventricular assist device (LVAD)medicine.medical_treatmentHemodynamicsBlood Pressure02 engineering and technology030204 cardiovascular system & hematology0302 clinical medicineCeliac ArteryParticle image velocimetry (PIV)Phantoms ImagingAbdominal aortaModels CardiovascularEquipment DesignMiddle AgedTreatment Outcomemedicine.anatomical_structureEchocardiographyCardiologyEquipment FailureRadiologyGastrointestinal HemorrhageRheologyBlood Flow VelocityArterymedicine.medical_specialty0206 medical engineeringBiomedical EngineeringBiophysicsAnastomosis03 medical and health sciencesInternal medicinemedicine.arterySettore ING-IND/12 - Misure Meccaniche E TermichemedicineHumansAbdominal aortaGastrointestinal bleedingbusiness.industrymedicine.disease020601 biomedical engineeringTrunkEquipment Failure AnalysisBiophysicVentricular assist deviceHeart failureHeart-Assist DevicesbusinessMedical Engineering &amp; Physics
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Adherence to growth hormone (GH) therapy in naïve to treatment GH-deficient children: data of the Italian Cohort from the Easypod Connect Observation…

2019

Background: With the use of non-objective measurement, adherence to growth hormone (GH) therapy has been reported suboptimal in a large proportion of patients, and poor adherence has been shown to affect short-term growth response in patients receiving GH treatment. Objective: The Easypod™ electronic device allows objective measurement of adherence. In this study, we report 3-year prospective adherence data of the Italian cohort of naïve GH deficient (GHD) children extrapolated from the Easypod Connect Observational Study (ECOS) database. Patients and methods: Seventy-three GHD children naïve to GH treatment were included in the analysis. 22 Italian centers participated in the study. Result…

MalePediatricsDatabases FactualChildren; ECOS; GHD; Growth hormone; Short statureEndocrinology Diabetes and MetabolismChildren; ECOS; GHD; Growth hormone; Short stature;Children; ECOS; GHD; Growth hormone; Short stature; Adolescent; Child; Cohort Studies; Databases Factual; Dwarfism Pituitary; Female; Growth Disorders; Human Growth Hormone; Humans; Italy; Male; Medication Adherence; Telemedicine; Medical Records Systems Computerized; Wearable Electronic DevicesGrowth hormoneCohort Studies0302 clinical medicineEndocrinologyChildChildrenGrowth DisordersHuman Growth HormoneChildren ECOS GHD Growth hormone Short statureObjective measurementSettore MED/38TelemedicineItaly030220 oncology & carcinogenesisCohortFemaleOriginal ArticleMedical Records Systemsmedicine.symptomCohort studymedicine.medical_specialtyAdolescentMedical Records Systems ComputerizedDwarfism030209 endocrinology & metabolismShort statureMedication AdherenceDatabasesWearable Electronic Devices03 medical and health sciencesmedicineHumansIn patientDwarfism PituitaryGrowth hormoneFactualbusiness.industryComputerizedShort staturePituitaryGh treatmentECOSObservational studybusinessGHDJournal of Endocrinological Investigation
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Predilation technique with balloon angioplasty to facilitate percutaneous groin access of large size sheath through scar tissue

2017

Purpose Percutaneous remote access for endovascular aortic repair is an advantageous alternative to open access. Previous surgery in the femoral region and the presence of synthetic vascular grafts in the femoral/iliac arteries represent major limitations to percutaneous remote access. The aim of this study was to evaluate an original technique used for enabling percutaneous remote access for thoracic or abdominal endovascular aortic repair in patients with scar tissue and/or a vascular graft in the groin. Methods Twenty-five consecutive patients with a thoracic (11/25; 44%) or an aortic aneurysm (14/25; 66%) and with a synthetic vascular graft in the groin (16/25; 64%) or a redo groin acce…

MalePercutaneousmedicine.medical_treatment030204 cardiovascular system & hematologyBalloonEndovascular aneurysm repairSettore MED/22 - Chirurgia Vascolarecalcificationendovascular aneurysm repairAortic aneurysm0302 clinical medicinesheathprosthetic graftballoon angioplastyVascular closure device030212 general & internal medicineAged 80 and over10042 Clinic for Diagnostic and Interventional RadiologyVascular Access Deviceultrasonographyvascular closure deviceGeneral MedicineEquipment Design2746 SurgeryBlood Vessel Prosthesimedicine.anatomical_structureTreatment OutcomeFemaleRadiologyCardiology and Cardiovascular MedicineVascular Access DevicesHumanmedicine.medical_specialtycomplication610 Medicine & healthGroin2705 Cardiology and Cardiovascular MedicineAneurysm; balloon angioplasty; calcification; complications; endovascular aneurysm repair; infection; prosthetic graft; sheath; ultrasonography; vascular closure devices; Aged; Aged 80 and over; Angioplasty Balloon; Aortic Aneurysm Abdominal; Aortic Aneurysm Thoracic; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Catheterization Peripheral; Cicatrix; Equipment Design; Female; Groin; Humans; Male; Treatment Outcome; Ultrasonography Interventional; Vascular Access Devices; Surgery; Radiology Nuclear Medicine and Imaging; Cardiology and Cardiovascular Medicine03 medical and health sciencesBlood Vessel Prosthesis ImplantationCicatrixBlood vessel prosthesisAngioplastyCatheterization Peripheralmedicine2741 Radiology Nuclear Medicine and ImagingHumansRadiology Nuclear Medicine and imagingUltrasonography InterventionalAgedGroinAortic Aneurysm Thoracicbusiness.industrymedicine.diseaseAneurysminfectionSurgery10020 Clinic for Cardiac SurgeryBlood Vessel ProsthesisSurgerybusinessAngioplasty BalloonAortic Aneurysm Abdominal
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