Search results for " distress"

showing 10 items of 351 documents

Promising Strategies for Preserving Adult Endothelium Health and Reversing Its Dysfunction: From Liquid Biopsy to New Omics Technologies and Noninvas…

2022

The endothelium has multiple functions, ranging from maintaining vascular homeostasis and providing nutrition and oxygen to tissues to evocating inflammation under adverse conditions and determining endothelial barrier disruption, resulting in dysfunction. Endothelial dysfunction represents a common condition associated with the pathogenesis of all diseases of the cardiovascular system, as well as of diseases of all of the other systems of the human body, including sepsis, acute respiratory distress syndrome, and COVID-19 respiratory distress. Such evidence is leading to the identification of potential biomarkers and therapeutic targets for preserving, reverting, or restoring endothelium in…

AdultRespiratory Distress SyndromeendotheliumOrganic ChemistryLiquid BiopsyCOVID-19General Medicineendothelium dysfunctionCatalysisComputer Science Applicationsnewer omics technologieInorganic Chemistrybiomarkers and therapeutic targetsHumansSettore MED/05 - Patologia ClinicaEndothelium VascularPhysical and Theoretical ChemistryMolecular BiologyBiomarkersSpectroscopynetwork medicine
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Stress in Medical Students: PRIMES, an Italian, Multicenter Cross-Sectional Study

2022

Medical students (MSs) are healthcare workers and must also cope with education-related stressors. This study aims to assess factors associated with perceived stress in Italian MSs. A cross-sectional study was conducted in 12 Italian medical schools (MSCs) in November 2018. A questionnaire assessed socio-demographic characteristics, habits, opinions about MSC, and concerns about the future. Stress was assessed with the PSS-10. Descriptive and univariable tests were performed. A linear model was fitted to find associations of the PSS-10 score with characteristics. There were 2513 collected questionnaires. Median PSS-10 score was 18 (IQR 11). Median age was 22 (IQR 4) and 61% of the sample wa…

AdultStudents MedicalschoolHealth Toxicology and Mutagenesiscross-sectional studiesStressmedicalpsychological distrecross-sectional studies; medical; medical; psychological; psychological distress; schools; stress; studentsYoung Adultpsychological distressstreSurveys and QuestionnairesAdaptation Psychologicalcross-sectional studies; medical; psychological; psychological distress; schools; stress; students; Adaptation Psychological; Adult; Cross-Sectional Studies; Female; Humans; Schools Medical; Stress Psychological; Surveys and Questionnaires; Young Adult; Students MedicalHumansAdaptationSchools MedicalSchoolsstudentscross-sectional studies medical psychological psychological distress schools stress studentsPublic Health Environmental and Occupational Healthpsychological distress; stress; psychological; schools; medical; students; medical; cross-sectional studiescross-sectional studiePsychologicalFemaleStress PsychologicalInternational Journal of Environmental Research and Public Health
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The Association between Dietary Habits, Substance Use, and Mental Distress among Adults in Southern Norway: A Cross-Sectional Study among 28,047 Adul…

2021

The aim of the present study was to examine associations between dietary habits, substance use, and mental distress among adults. This cross-sectional study was conducted in 2019 using an online questionnaire and included 28,047 adults (≥18 years) from Southern Norway. Multivariable logistic regression models stratified by gender were used to examine the associations between different lifestyle behaviors and mental distress. The results showed increased odds of mental distress among males and females with low consumption of vegetables (OR:1.26

AdultTobacco SmokelessCross-sectional studySubstance-Related DisordersHealth Toxicology and MutagenesisPopulationComputer-assisted web interviewingLogistic regressionArticlesmokingOddsMental distressmental distressVegetablesadultsMedicineHumansAssociation (psychology)educationeducation.field_of_studybusiness.industryalcoholPublic Health Environmental and Occupational HealthRFeeding Behaviorsmokeless tobaccoCross-Sectional StudiesSmokeless tobaccoVDP::Medisinske Fag: 700::Helsefag: 800MedicinebusinessdietDemographyInternational Journal of Environmental Research and Public Health
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Variable pulmonary manifestations in Chitayat syndrome: Six additional affected individuals

2020

Hand hyperphalangism leading to shortened index fingers with ulnar deviation, hallux valgus, mild facial dysmorphism and respiratory compromise requiring assisted ventilation are the key features of Chitayat syndrome. This condition results from the recurrent heterozygous missense variant NM_006494.2:c.266A>G; p.(Tyr89Cys) in ERF on chromosome 19q13.2, encoding the ETS2 repressor factor (ERF) protein. The pathomechanism of Chitayat syndrome is unknown. To date, seven individuals with Chitayat syndrome and the recurrent pathogenic ERF variant have been reported in the literature. Here, we describe six additional individuals, among them only one presenting with a history of assisted ventil…

Adultbronchomalacia2716 Genetics (clinical)hyperphalangismPediatricsmedicine.medical_specialtyAdolescent10039 Institute of Medical Genetics610610 Medicine & healthChitayat syndromeFingersYoung Adult03 medical and health sciences1311 Geneticsrespiratory distressExome SequencingGeneticsmedicineHumansMissense mutationGenetic Predisposition to DiseaseHallux ValgusRespiratory systemChildGenetics (clinical)030304 developmental biologyCHITAYAT SYNDROME0303 health sciencesPierre Robin SyndromebiologyRespiratory distressbusiness.industry030305 genetics & heredityFaciesmedicine.diseasebiology.organism_classificationPhenotype3. Good healthRepressor ProteinsValgusERFChild Preschoolulnar deviation570 Life sciences; biologyFemaleUlnar deviationBronchomalaciabusinessAmerican Journal of Medical Genetics Part A
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Congenital hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta: case report.

2005

A newborn with an unusual association of hepatic mesenchymal hamartoma and mesenchymal stem villous hyperplasia of the placenta is presented. At birth, the large hepatic mass caused severe respiratory distress necessitating early surgical intervention. This report on the association of hepatic mesenchymal hamartoma and mesenchymal stem villous hyperplasia of the placenta strongly suggests a common pathogenetic origin of the 2 lesions.

Adultcongenital hereditary and neonatal diseases and abnormalitiesPathologymedicine.medical_specialtyHepatic massHamartomaPlacentaUltrasonography PrenatalDiagnosis DifferentialMesodermPostoperative ComplicationsPregnancyPlacentamedicineEdemaHepatectomyHumansRespiratory Distress Syndrome NewbornHyperplasiaRespiratory distressbusiness.industryLiver DiseasesMesenchymal stem cellInfant NewbornGeneral MedicineHydatidiform MoleHyperplasiamedicine.diseaseJaundice Obstructivemedicine.anatomical_structureHepatic Mesenchymal Hamartomaembryonic structuresPediatrics Perinatology and Child HealthUterine NeoplasmsSurgeryFemaleChorionic VillibusinessJournal of pediatric surgery
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Study on maternal, fetal and amniotic prolactin in gestational diabetic women, at term.

1982

In order to determine whether prolactin secretion was affected in diabetic pregnancy, maternal, fetal and amniotic fluid prolactin (PRL) concentrations were measured in gestational non treated diabetic women at parturition. Amniotic fluid PRL levels, though higher than those in maternal and fetal serum, were significantly lower than those of the controls (p less than 0.005); no case of respiratory distress syndrome or congenital malformation was found at birth.

Adultendocrine systemmedicine.medical_specialtyAmniotic fluidAdolescentEndocrinology Diabetes and MetabolismPregnancy in DiabeticsEndocrinologyPregnancyReference ValuesInternal medicineDiabetes mellitusInternal MedicinemedicineMaternal fetalHumansFetusRespiratory distressbusiness.industryDeciduaGeneral Medicinemedicine.diseaseAmniotic FluidFetal BloodProlactinProlactinEndocrinologymedicine.anatomical_structureGestationFemalebusinesshormones hormone substitutes and hormone antagonistsActa diabetologica latina
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Noise annoyance predicts symptoms of depression, anxiety and sleep disturbance 5 years later. Findings from the Gutenberg Health Study

2020

Abstract Background Cross-sectional studies have shown that noise annoyance is strongly associated with mental distress, however, its long-term effects on mental health is unknown. We therefore investigated whether noise annoyance predicts depression, anxiety and sleep disturbance in a large, representative sample 5 years later. Methods We investigated longitudinal data of N = 11 905 participants of the Gutenberg Health Study, a population-based, prospective, single-centre cohort study in mid-Germany (age at baseline 35–74 years). Noise annoyance was assessed at baseline and 5-year follow-up (sources: road traffic, aircraft, railways, industrial, neighbourhood indoor and outdoor noise; and …

Adultmedicine.medical_specialtyCross-sectional studyAnnoyanceAnxiety030204 cardiovascular system & hematologyAudiologyCohort Studies03 medical and health sciencesMental distress0302 clinical medicineGermanySurveys and QuestionnairesHumansMedicineProspective Studies030212 general & internal medicineDepression (differential diagnoses)Sleep disorderDepressionbusiness.industryPublic Health Environmental and Occupational HealthEnvironmental Exposuremedicine.diseaseAnxiety DisordersMental healthCross-Sectional StudiesNoise TransportationAnxietyFemalemedicine.symptomSleepbusinesshuman activitiesCohort studyEuropean Journal of Public Health
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Acute Respiratory Distress Syndrome Caused by Pulmonary Nocardiosis in a Patient With Systemic Lupus Erythematosus

2005

Nocardia is a gram-positive bacillus that infects mainly immunodepressed patients. Its association with lupus erythematosus has been described only occasionally and we have found no reports in the literature of an association between lupus and acute respiratory distress syndrome due to pulmonary nocardiosis. We present such a case and discuss the mechanisms that make this lung infection so virulent as well as its epidemiological and microbiological characteristics, clinical presentation, diagnosis, and treatment.

Adultmedicine.medical_specialtyPulmonary nocardiosisLung infectionNocardia InfectionsAcute respiratory distressimmune system diseasesEpidemiologyHumansLupus Erythematosus SystemicMedicineskin and connective tissue diseasesLungRespiratory Distress SyndromeLupus erythematosusSystemic lupus erythematosusbiologybusiness.industryNocardiaGeneral Medicinebiology.organism_classificationmedicine.diseaseDermatologyImmunologyFemaleRadiography ThoracicbusinessArchivos de Bronconeumología ((English Edition))
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Caring for People With Dementia Under COVID-19 Restrictions: A Pilot Study on Family Caregivers

2021

IntroductionThe present pilot study examined to what extent the COVID-19 lockdown affected the behavioral and psychological symptoms of dementia (BPSD) in people with dementia and worsened their family caregivers’ distress. The associations between changes in the BPSD of relatives with dementia (RwD) and in their caregivers’ distress, and sense of social and emotional loneliness, and resilience were also investigated.Materials and MethodsThirty-five caregivers of RwD attending formal healthcare services before the COVID-19 lockdown volunteered for the study, and were interviewed by phone during the lockdown. Caregivers completed the NeuroPsychiatric Inventory (NPI) to assess their care reci…

Agingdementia family caregivers caregivers’ distress behavioral and psychological symptoms of dementia (BPSD) loneliness resilience COVID-19 lockdownCoronavirus disease 2019 (COVID-19)Cognitive Neurosciencemedia_common.quotation_subjectNeurosciences. Biological psychiatry. Neuropsychiatrycaregivers’ distress03 medical and health sciences0302 clinical medicineHealth caremedicinelonelinessDementiaresiliencemedia_common030214 geriatricsbusiness.industryFamily caregiversCaring for people with dementiaLonelinessBrief Research Reportmedicine.diseaseDistressCOVID-19 lockdownPsychological resiliencemedicine.symptomfamily caregiversbusinessPsychologybehavioral and psychological symptoms of dementia (BPSD)030217 neurology & neurosurgeryNeuroscienceClinical psychologydementiaRC321-571Frontiers in Aging Neuroscience
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Work stress, fatigue and risk behaviors at the wheel: Data to assess the association between psychosocial work factors and risky driving on Bus Rapid…

2017

This Data in Brief (DiB) article presents a hierarchical multiple linear regression model that examine the associations between psychosocial work factors and risk behaviors at the wheel in Bus Rapid Transit (BRT) drivers (n=524). The data were collected using a structured self-administrable questionnaire made of measurements of wok stress (job strain and effort- reward imbalance), fatigue (need for recovery and chronic fatigue), psychological distress and demographics (professional driving experience, hours driven per day and days working per week). The data contains 4 parts: descriptive statistics, bivariate correlations between the study variables and a regression model predicting risk be…

Applied psychologyPoison controlPsychological distresslcsh:Computer applications to medicine. Medical informaticsRisk behaviorsTransportes0502 economics and businessPsychology0501 psychology and cognitive scienceslcsh:Science (General)Fatigue050107 human factorsSimulationBus rapid transitWork stress050210 logistics & transportationBus Rapid TransportMultidisciplinaryJob strainDescriptive statisticsFatiga05 social sciencesHuman factors and ergonomicsRegression analysisChronic fatigueProfessional driverslcsh:R858-859.7PsychologyEstrés laboralPsychosocialhuman activitiesBRTlcsh:Q1-390Data in Brief
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