Search results for " early"

Distributed estimation and control of water distribution networks by logical consensus

2014

In this study we present a methodology for backflow detec- tion through the interpretation of results from a network of Automatic Meter Reading. The approach is based on the so– called logical consensus theory and consists of a distributed failure detection and system reconfiguration. The effective- ness of the proposed method is showed through simulation within a prototypical water distribution network.

"Esse Malo Quam videri". Sangre y mérito en la orden de Malta a través de la literatura de ficción (Italia, siglos XVI-XVII)

2015

Textos de comunicaciones defendidas en la XIII Reunión Científica de la Fundación Española de Historia Moderna, previa evaluación ciega por pares.

Le mouvement des idées monétaires dans l'Europe moderne

2014

Ce chapitre vise à fournir une vue de l'évolution des idées monétaires dans l'Europe moderne. Il s'alimente notamment des textes des auteurs du présent livre pour en dégager quelques leçons. Dans un premier temps, il discutera du sens du substantif " mercantilisme " tel qu'il a été construit depuis le milieu du dix-huitième siècle : examiner les fondements historiques de cette notion permettra d'en montrer les impasses. Il présentera, dans un second temps, une catégorisation des auteurs construite à partir de leur rapport au pouvoir.

Introduction. Les pensées monétaires dans l'Europe moderne : contexte et intentions

2014

Ce texte introduit le livre et présente ses objectifs et sa structure. Ce livre traite du déploiement des idées monétaires dans le monde européen de l'époque moderne, depuis les écrits de Nicolas Copernic (1517) jusqu'à la veille de la publication de l'ouvrage économique majeur écrit par Adam Smith (1776) . Il met l'accent sur le contexte historique dans le cadre duquel ces idées monétaires ont vu le jour. Il montre la grande variété des contextes et des idées bien au-delà des espaces, des auteurs et des thèmes généralement étudiés, en intégrant des territoires peu étudiés par les économistes, en mettant au jour des approches et des auteurs oubliés, en tentant, enfin, de restituer la riches…

Resistance of keratinocytes to TGFbeta-mediated growth restriction and apoptosis induction accelerates re-epithelialization in skin wounds.

2002

The pleiotropic growth factor TGFβ plays an important role in regulating responses to skin injury. TGFβ targets many different cell types and is involved in all aspects of wound healing entailing inflammation,re-epithelialization, matrix formation and remodeling. To elucidate the role of TGFβ signal transduction in keratinocytes during cutaneous wound healing, we have used transgenic mice expressing a dominant negative type II TGFβ receptor exclusively in keratinocytes. We could demonstrate that this loss of TGFβ signaling in keratinocytes led to an accelerated re-epithelialization of full thickness excisional wounds accompanied by an increased proliferation in keratinocytes at the wound ed…

LOW VITAMIN D SERUM LEVEL IS RELATED TO RAPID, EARLY AND SUSTAINED VIROLOGICAL RESPONSE TO IFN-BASED THERAPY IN GENOTYPE 1 CHRONIC HEPATITIS C

2011

I Segni premonitori del Giudizio Universale in un inedito testo tedesco del XV secolo

2022

Numerous lists of the premonitory signs of the Last Judgment and wider narratives focussing on the same motif, which presents variants and articulated typologies, circulated throughout the Middle Ages, both in Latin and in the vernacular languages. Also in Germany the motif continues to be present in literature up to the threshold of the modern age, with the Lutheran Reform which is, also in this case, a watershed. The purpose of the contribution is the philological-literary analysis of a prose composition, in late German, devoted to the 15 Signs of Judgment, still unpublished, preserved in the ms. München, BStB cgm 522 (ff. 163v-166v), datable around 1470. The codex contains a miscellany o…

Random, asynchronous, and asymmetric transcriptional activity of enhancer-flanking major immediate-early genes ie1/3 and ie2 during murine cytomegalo…

2001

ABSTRACT The lungs are a major organ site of cytomegalovirus (CMV) pathogenesis, latency, and recurrence. Previous work on murine CMV latency has documented a high load and an even distribution of viral genomes in the lungs after the resolution of productive infection. Initiation of the productive cycle requires expression of the ie1/3 transcription unit, which is driven by the immediate-early (IE) promoter P 1/3 and generates IE1 and IE3 transcripts by differential splicing. Latency is molecularly defined by the absence of IE3 transcripts specifying the essential transactivator protein IE3. In contrast, IE1 transcripts were found to be generated focally and randomly, reflecting sporadic P …

ST segment elevations: Always a marker of acute myocardial infarction?

2013

AbstractChest pain is one of the chief presenting complaints among patients attending Emergency department. The diagnosis of acute myocardial infarction may be a challenge. Various tools such as anamnesis, blood sample (with evaluation of markers of myocardial necrosis), ultrasound techniques and coronary computed tomography could be useful. However, the interpretation of electrocardiograms of these patients may be a real concern. The earliest manifestations of myocardial ischemia typically interest T waves and ST segment. Despite the high sensitivity, ST segment deviation has however poor specificity since it may be observed in many other cardiac and non-cardiac conditions. Therefore, when…

Measles virus enhances the expression of cellular immediate-early genes and DNA-binding of transcription factor AP-1 in lung epithelial A549 cells.

2002

In this work we investigated the effect of measles virus (MV) infection on the expression of immediate-early genes junB, c-jun and c-fos mRNA as well as AP-1 DNA-binding activity in the lung epithelial-like adenocarcinoma cell line A549. The transcription factor AP-1, which is a group of dimeric complexes of the Fos and Jun family proteins, is an important regulator in many cellular responses to different extracellular stimuli. Membrane cofactor protein CD46, which acts as a receptor for laboratory-adapted and vaccine strains of MV, has been reported to associate with beta1 integrin molecules, which are known to trigger signaling events and activate immediate-early genes. The expression of …