Search results for " effect"
showing 10 items of 7524 documents
Auditory Emotion Word Primes Influence Emotional Face Categorization in Children and Adults, but Not Vice Versa
2018
In order to assess how the perception of audible speech and facial expressions influence one another for the perception of emotions, and how this influence might change over the course of development, we conducted two cross-modal priming experiments with three age groups of children (6-, 9-, and 12-years old), as well as college-aged adults. In Experiment 1, 74 children and 24 adult participants were tasked with categorizing photographs of emotional faces as positive or negative as quickly as possible after being primed with emotion words presented via audio in valence-congruent and valence-incongruent trials. In Experiment 2, 67 children and 24 adult participants carried out a similar cate…
Proanthocyanidins and Where to Find Them: A Meta-Analytic Approach to Investigate Their Chemistry, Biosynthesis, Distribution, and Effect on Human He…
2021
Proanthocyanidins (PACs) are a class of polyphenolic compounds that are attracting considerable interest in the nutraceutical field due to their potential health benefits. However, knowledge about the chemistry, biosynthesis, and distribution of PACs is limited. This review summarizes the main chemical characteristics and biosynthetic pathways and the main analytical methods aimed at their identification and quantification in raw plant matrices. Furthermore, meta-analytic approaches were used to identify the main plant sources in which PACs were contained and to investigate their potential effect on human health. In particular, a cluster analysis identified PACs in 35 different plant famili…
Electrocatalysis of neurotransmitter catecholamines by 2,4,6-triphenylpyrylium ion immobilized inside zeolite Y supercages
1999
2,4,6-Triphenylpyrylium ions entrapped inside the supercages of Y zeolite exert a remarkable catalytic effect toward the electrochemical oxidation of dopamine and norepinephrine (neurotrasmitter catecholamines) in neutral aqueous media. Domenech Carbo, Antonio, Antonio.Domenech@uv.es
Cytotoxic effects of individual and combined sterigmatocystin and nivalenol on liver hepatocellular carcinoma cells
2020
Abstract Since humans are exposed to different mycotoxins through daily intake, there is increasing concern about the adverse effects of the interactions between them. Cytotoxicity of sterigmatocystin (STE) and nivalenol (NIV) alone and in combination in human hepatocarcinoma (HepG2) cells was evaluated by MTT assay. Furthermore, ROS production and alteration of ΔΨm as mechanisms of action were assessed. Cells were treated with concentrations ranging from 0.15 to 5 μM for NIV and from 0.78 to 50 μM for STE individually and in binary combinations. The combination ratio between the mixture STE + NIV was 10:1. The IC50 values of NIV ranged from 0.96 to 0.66 μM, whereas no IC50 values were obta…
Some aspects related to stability, critical concentrations and kinetics of flocculation of the calcium phytate colloid
1986
Abstract As 99mTcCa phytate is an important radiopharmaceutical and its colloidal nature presents problems, we investigated some of them. This work describes the study of the colloidal behaviour of the calcium phytate colloid in terms of its formation, stability and kinetics of flocculation. The study of spontaneous, and centrifugation-induced flocculation allows the determination of two critical concentrations of sol flocculation. The titrations of calcium phytate colloid at different concentrations provide information on the colloidal formation conditions. Moreover, a study on flocculation kinetics was made by turbidity measurements.
Localization and interactions of melatonin in dry cholesterol/lecithin mixed reversed micelles used as cell membrane models
2005
The state of melatonin confined in dry cholesterol/lecithin mixed reversed micelles dispersed in CCl4 was investigated using 1H-NMR and FT-IR spectroscopies as a function of the melatonin to lecithin molar ratio (R(MLT)) and of the cholesterol to lecithin molar ratio (R(CHL)). An analysis of experimental results leads to the hypothesis that, independent of R(MLT) and as a consequence of anisotropic melatonin/lecithin, melatonin/cholesterol and cholesterol/lecithin interactions, melatonin is totally solubilized in reversed micelles. Melatonin is mainly located in and oriented in the nanodomain constituted by the hydrophilic groups of cholesterol and lecithin. A competition of melatonin and c…
Control of Morphology and Corona Composition in Aggregates of Mixtures of PS-b-PAA and PS-b-P4VP Diblock Copolymers: Effects of Solvent, Water Conten…
2014
The morphologies and corona compositions in aggregates of mixtures of PS-b-PAA and PS-b-P4VP diblock copolymers are influenced by controllable assembly parameters such as water content, block copolymer molar ratios, and solvent effects as well as the hydrophilic block lengths and block length ratios. All these factors can affect the morphology of the aggregates as well as their corona composition, the latter especially in vesicles, where two interfaces are involved. The morphologies and corona compositions of the aggregates were investigated by transmission electron microscopy and electrophoretic mobility, respectively. They depend, to a large extent, on the solubility of P4VP and PAA in th…
Response to methimazole in Graves' disease
1995
Summary OBJECTIVE A variety of regimens continue to be used In the treatment of Graves' disease with antithyrold drugs. We have lnvestigated the factors which determine the initial response to methimazole (time until euthyroidism Is achieved) In Graves' disease. PATIENTS Five hundred and nine patients with Graves' disease in different European countries with normal and subnormal iodine supply. Patients were randomized to treatment with either 10 or 40mg of methimazole per day for one year, with levothyroxine supplementation as required to maintain euthyroidism. Investigations were carried out before treatment and at 3 and 6 weeks and 3, 6, 9 and 12 months. MEASUREMENTS Response was assessed…
Memory for time intervals is impaired in left hemi-Parkinson patients.
2004
The basal ganglia have been proposed as one of the neural correlates of timekeeping functions. Both encoding and memory retrieval components for time perception are impaired in Parkinson's disease (PD). The aim of our study was to investigate in hemi-Parkinsonian patients the existence of a specific alteration in memory for time depending on the affected side, to better understand the contribution of the left or right basal ganglia circuits in different components of time perception. Right and left hemi-PD patients performed a time reproduction task in which they were required to reproduce in the same session short (5 s) and long (15 s) time intervals, in off- and on-therapy condition. Whil…
Circadian rhythm and effects of light on cAMP content of the dwarf hamster suprachiasmatic nucleus
1998
The present study was conducted in the dwarf hamster (Phodopus sungorus) to investigate whether a circadian rhythm is present in the content of the second messenger cyclic adenosine 3',5'-monophosphate (cAMP) in the suprachiasmatic nucleus (SCN), the endogenous clock in mammals. In animals held under light/dark conditions (LD), we observed high levels at the end of the light phase and low levels during the night in frozen SCN punches. In animals held in continuous dark, a similar rhythm was seen although a second peak was present in the subjective day. In senile hamsters under LD, the decrease of cAMP levels at the light transition was not seen. These data, obtained for the first time from …