Search results for " enhancement."
showing 10 items of 513 documents
Automatic Myocardial Infarction Evaluation from Delayed-Enhancement Cardiac MRI Using Deep Convolutional Networks
2021
In this paper, we propose a new deep learning framework for an automatic myocardial infarction evaluation from clinical information and delayed enhancement-MRI (DE-MRI). The proposed framework addresses two tasks. The first task is automatic detection of myocardial contours, the infarcted area, the no-reflow area, and the left ventricular cavity from a short-axis DE-MRI series. It employs two segmentation neural networks. The first network is used to segment the anatomical structures such as the myocardium and left ventricular cavity. The second network is used to segment the pathological areas such as myocardial infarction, myocardial no-reflow, and normal myocardial region. The segmented …
Evaluation of Disaggregation Methods for Downscaling MODIS Land Surface Temperature to Landsat Spatial Resolution in Barrax Test Site
2016
Thermal infrared (TIR) data are usually acquired at a coarser spatial resolution (CR) than visible and near infrared (VNIR). Several disaggregation methods have been recently developed to enhance the TIR spatial resolution using VNIR data. These approaches are based on the retrieval of a relation between TIR and VNIR data at CR, or training of a neural network, to be applied at the fine resolution afterward. In this work, different disaggregation methods are applied to the combination of two different sensors in the experimental test site of Barrax, Spain. The main objective is to test the feasibility of these techniques when applied to satellites provided with no TIR bands. Landsat and mod…
Ozone and autologous therapies [abstract]
2019
PURPOSE: One of the proven effects of Ozone Therapy, is the releasing of Growth Factors from Platelets. Some other therapies can have similar effects. Autologous Therapies can be defined as “The therapy that is done by transferring cells, tissues, body liquids originating from the recipient rather than from donor.” The purpose of this presentation is to give information on those therapies.
 
 DISCUSSION: There are several therapies in this group, such as Stem Cell Therapies, Dentric Cell Vaccine Therapy, Autologous immune enhancement therapy, etc. But most of them are so difficult that we can not practise at office conditions where some therapies can be done at small clinic and pr…
LogDet divergence-based metric learning with triplet constraints and its applications.
2014
How to select and weigh features has always been a difficult problem in many image processing and pattern recognition applications. A data-dependent distance measure can address this problem to a certain extent, and therefore an accurate and efficient metric learning becomes necessary. In this paper, we propose a LogDet divergence-based metric learning with triplet constraints (LDMLT) approach, which can learn Mahalanobis distance metric accurately and efficiently. First of all, we demonstrate the good properties of triplet constraints and apply it in LogDet divergence-based metric learning model. Then, to deal with high-dimensional data, we apply a compressed representation method to learn…
Generation of lentivirus vectors using recombinant baculoviruses
2008
In spite of advances in conventional four-plasmid transient transfection methods and development of inducible stable production cell lines, production of replication-defective lentiviral vectors in clinical scale has been challenging. Baculovirus technology offers an alternative to scalable virus production as a result of fast and easy production of baculoviruses, efficient transduction of mammalian cells and safety of the baculoviruses. As a first step toward scalable lentiviral production system, we have constructed four recombinant baculoviruses: the BAC-transfer virus expresses green fluorescent protein (GFP) as a transgene and BAC-gag-pol, BAC-vesicular stomatitis virus glycoprotein G …
Blood Flow and Tissue Oxygenation of Human Tumors: An Update
1992
It is generally accepted that tumor microcirculation, blood flow, oxygen and nutrient supply, tissue pH distribution, and the bioenergetic status (factors which are usually closely linked and which define the so-called cellular microenvironment) can markedly influence the therapeutic response of malignant tumors. Tumor blood flow is the major determinant for intra-tumor pharmacokinetics and (through modulation of the cellular microenvironment) of pharmacody-namics. The oxygen supply greatly determines the radiosensitivity of the tumors to be treated. The oxygen enhancement ratio, i.e., the ratio of doses with and without oxygen to produce the same biological effect is 2.7 to 3.0. O2 partial…
Gene therapy with growth factors for periodontal tissue engineering : a review
2011
The treatment of oral and periodontal diseases and associated anomalies accounts for a significant proportion of the healthcare burden, with the manifestations of these conditions being functionally and psychologically debilitating. A challenge faced by periodontal therapy is the predictable regeneration of periodontal tissues lost as a consequence of disease. Growth factors are critical to the development, maturation, maintenance and repair of oral tissues as they establish an extra-cellular environment that is conducive to cell and tissue growth. Tissue engineering principles aim to exploit these properties in the development of biomimetic materials that can provide an appropriate microen…
I giardini borbonici di Palermo tra conservazione e valorizzazione
2021
This essay, through the presentation of an educational experience regarding two Palermo parks-gardens, aims to offer a cognitive contribution and critical reflections, for the enhancement of these assets, with particular reference to section D) of the ICOMOS-IFLA Florence Charter. The heritage of the historic gardens in Palermo and Sicily, created by the Bourbon kings in the early nineteenth century, as an integral part of their royal estates, constitutes today a precious heritage not adequately valued, not recognized as a unicum, even in relation to similar Campania heritage. This heritage includes the Parco della Favorita, established by Ferdinand IV of Bourbon in 1799 and the d' Orlèans …
A Fuzzy Logic C-Means Clustering Algorithm to Enhance Microcalcifications Clusters in Digital Mammograms
2011
The detection of microcalcifications is a hard task, since they are quite small and often poorly contrasted against the background of images. The Computer Aided Detection (CAD) systems could be very useful for breast cancer control. In this paper, we report a method to enhance microcalcifications cluster in digital mammograms. A Fuzzy Logic clustering algorithm with a set of features is used for clustering microcalcifications. The method described was tested on simulated clusters of microcalcifications, so that the location of the cluster within the breast and the exact number of microcalcifications is known.
Exclusive transduction of human CD4+ T Cells upon systemic delivery of CD4-targeted lentiviral vectors
2015
Abstract Playing a central role in both innate and adaptive immunity, CD4+ T cells are a key target for genetic modifications in basic research and immunotherapy. In this article, we describe novel lentiviral vectors (CD4-LV) that have been rendered selective for human or simian CD4+ cells by surface engineering. When applied to PBMCs, CD4-LV transduced CD4+ but not CD4− cells. Notably, also unstimulated T cells were stably genetically modified. Upon systemic or intrasplenic administration into mice reconstituted with human PBMCs or hematopoietic stem cells, reporter gene expression was predominantly detected in lymphoid organs. Evaluation of GFP expression in organ-derived cells and blood …