Search results for " expo"
showing 10 items of 1465 documents
Ramadan Exposure In Utero and Child Mortality in Burkina Faso: Analysis of a Population-Based Cohort Including 41,025 Children.
2017
Ramadan exposure in utero can be regarded as a natural experiment with which to study how nutritional conditions in utero influence susceptibility to disease later in life. We analyzed data from rural Burkina Faso on 41,025 children born between 1993 and 2012, of whom 25,093 were born to Muslim mothers. Ramadan exposure was assigned on the basis of overlap between Ramadan dates and gestation, creating 7 exclusive categories. We used proportional hazards regression with difference-in-differences analysis to estimate the association between Ramadan exposure at different gestational ages and mortality among children under 5 years of age. Under-5 mortality was 32 deaths per 1,000 child-years. U…
Outside-host phage therapy as a biological control against environmental infectious diseases
2018
Background Environmentally growing pathogens present an increasing threat for human health, wildlife and food production. Treating the hosts with antibiotics or parasitic bacteriophages fail to eliminate diseases that grow also in the outside-host environment. However, bacteriophages could be utilized to suppress the pathogen population sizes in the outside-host environment in order to prevent disease outbreaks. Here, we introduce a novel epidemiological model to assess how the phage infections of the bacterial pathogens affect epidemiological dynamics of the environmentally growing pathogens. We assess whether the phage therapy in the outside-host environment could be utilized as a biologi…
Physical and Genetic Interactions Link the Yeast Protein Zds1p with mRNA Nuclear Export
2005
Eukaryotic gene expression requires the export of mRNA from the nucleus to the cytoplasm. The DEAD box protein Dbp5p is an essential export factor conserved from yeast to man. A fraction of Dbp5p forms a complex with nucleoporins of the cytoplasmic filaments of the nuclear pore complex. Gfd1p was identified originally as a multicopy suppressor of the rat8-2 ts allele of DBP5. Here we reported that Dbp5p and Gfd1p interact with Zds1p, a protein previously identified as a multicopy suppressor in several yeast genetic screens. By using the two-hybrid system, we showed that Zds1p interacts in vivo with both Gfd1p and Dbp5p. In vitro binding experiments revealed that Gfd1p and Dbp5p bind directl…
Lack of mutagenic and co-mutagenic effects of magnetic fields during magnetic resonance imaging
2001
Mutagenic and co-mutagenic effects of static, pulsed bipolar gradient, and high-frequency magnetic fields, as well as combinations of them, were examined using the Ames test. The Ames test using Salmonella typhimurium bacteria, wild-type strain RTA, preincubation assay, without metabolic activation, was performed. All combinations of magnetic fields were tested with and without co-exposure to N-methyl-N′-nitro-N-nitrosoguanidine and benzo[a]pyrene-4,5-oxide, ethylene oxide, carboplatin, or cisplatin. As expected, chemical mutagens caused a clear-cut increase of the revertants in the Ames test. However, neither the static fields nor a combination of a static magnetic field with the time-vary…
Fleuve en ville. Infrastructures touristiques à l'Expo 2008 Saragosse
2011
Avec la montée en puissance des grandes expositions, soutenues par les villes qui se livrent à une course à l’image par l’intermédiaire d’événements culturels, une nouvelle catégorie de tourisme s’est imposée dans le territoire urbain des villes : le tourisme culturel. Dans des territoires où l’offre culturelle est limitée, l’événementiel peut être un moyen d’engager une dynamique nouvelle, qui peut jouer, à cet égard, un rôle fédérateur parmi les acteurs publics. Les impacts à différentes échelles sont multiples : sur le développement urbain, sur l’économie et le tourisme ainsi que sur le développement durable de façon plus globale. Les événements jouent actuellement un rôle pleinement pol…
Moving across the static magnetic field of a 1.5 T MRI scanner: Analysing compliance with Directive 2013/35/EU
2018
Abstract Does the exposure of magnetic resonance imaging personnel to static magnetic fields fully comply with Directive 2013/35/EU? Despite the obligation to satisfy this question, a general answer cannot be provided, nor are final satisfying good practices methods for exposure assessment currently available. In order to contribute to fix this problem, three different 1.5 T scanners are analysed and – by a new theoretical insight – a positive answer is provided.
Analisi delle evidenze epidemiologiche sui fattori di rischio indoor per malattie respiratorie e allergiche nelle strutture scolastiche [Analysis of …
2012
Il diritto a respirare aria sana nelle scuole è stato sancito già nell’anno 2001 in un documento dell’European Federation of Asthma and Allergy Associations che ha evidenziato scarsa attenzione e assenza di direttive specifiche dell’Unione Europea relativamente agli effetti sulla salute da inquinamento dell’aria nelle scuole, ed è sostenuto dal numero enorme di bambini e ragazzi che frequentano le aule scolastiche. Negli ultimi anni, a livello europeo si è sviluppato un sempre crescente interesse nei confronti dell’effetto della qualità dell’aria dell’indoor scolastico (IAQ) sulla salute dei ragazzi, e sono stati avviati numerosi progetti di ricerca internazionali mirati, appunto, a determi…
Alteration of serotonin system by polychlorinated biphenyls exposure.
2011
Although commercial production of polychlorinated biphenyls (PCBs) was banned in 1979, PCBs continue to be an environmental and health concern due to their high bioaccumulation and slow degradation rates. In fact, PCBs are still present in our food supply (fish, meat, and dairy products). In laboratory animals, exposure to single PCB congener or to mixtures of different congeners induces a variety of physiological alterations. PCBs cross the placenta and even exposure at low level is harmful for the foetus by leading to neurodevelopment alterations. Serotonin system which regulates many physiological functions from platelet activation to high cerebral processes and neurodevelopment is one o…
Response to Kruse-Plass et al. (2017) regarding the risk to non-target lepidopteran larvae exposed to pollen from one or more of three Bt maize event…
2017
We respond to the paper of Kruse-Plass et al. (Environ Sci Eur 29:12, 2017), published in this journal, regarding the risk to non-target lepidopteran larvae exposed to pollen from one or more of three Bt maize events (MON810, Bt11 and 1507). We emphasise that what is important for environmental risk assessment is not the number of pollen grains per se, but the degree of exposure of a NT lepidopteran larva to Bt protein contained in maize pollen. The main text of this response deals with general issues which Kruse-Plass et al. have failed to understand; more detailed refutations of each of their claims are given in Additional file 1. Valid environmental risk assessment requires direct measur…
Contribution of planktonic and benthic food sources to the diet of the reef-forming vermetid gastropod Dendropoma petraeum in the western Mediterrane…
2012
Abstract In the Mediterranean Sea, the vermetid Dendropoma petraeum (Monterosato, 1884) forms highly biodiverse reefs that have received increasing attention in recent years although very little is known about the food habit of this species. The main goal of this study was to describe the trophic role of planktonic and benthic food sources for D. petraeum . Specimens from three morphological zones of the reef (inner edge, cuvette and outer edge) at two sites with different wave exposure along the north-western coast of Sicily (Italy; western Mediterranean) were compared for δ 13 C and δ 15 N. Isotopic determinations were also carried out on potential food sources identified in epilithon, re…