Search results for " frequency"
showing 10 items of 1398 documents
Frequency dynamics of power systems with temporally distributed disturbances
2021
Abstract The frequency dynamics and stability of power systems is essentially affected by nature and characteristics of the disturbances occurring in the system. Conventionally, frequency transients are examined assuming a single disturbance applied at a given time. However, actual incidents in the power systems can be generally composed of a temporal sequence of events, and thus characterized by multiple power imbalances of different magnitudes and time offsets. The consideration of the effects of the temporal distribution of power imbalances is important for two main reasons: the impact on the frequency dynamics of the system in terms of frequency metrics such as minimum instantaneous fre…
HUMAN LEUKOCYTE ANTIGEN POLYMORPHISMS IN ITALIAN PRIMARY BILIARY CIRRHOSIS: A MULTICENTER STUDY OF 664 PATIENTS AND 1992 HEALTHY CONTROLS
2008
Genetic factors are critical in determining susceptibility to primary biliary cirrhosis (PBC), but there has not been a clear association with human leukocyte antigen (HLA) genes. We performed a multicenter case-control study and analyzed HLA class II DRB1 associations using a large cohort of 664 well-defined cases of PBC and 1992 controls of Italian ancestry. Importantly, healthy controls were rigorously matched not only by age and sex, but also for the geographical origin of the proband four grandparents (Northern, Central, and Southern Italy). After correction for multiple testing, DRB1*08 [odds ratio (OR), 3.3; 95% confidence interval (CI), 2.4-4.5] and DRB1*02 (OR 0.9; 95% CI 0.8-1.2) …
Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD
2008
Contains fulltext : 70183.pdf (Publisher’s version ) (Closed access) Previous studies have found heterogeneous association between DAT1-3'-UTR-VNTR and attention deficit hyperactivity disorder (ADHD). Various proportions of conduct disorder (CD) comorbidity in their ADHD samples may partially explain the observational discrepancies. Evidence for this comes from family and twin studies which found ADHD probands with CD (ADHD + CD) are genetically different from those without CD (ADHD - CD). Genotypes of 20 DAT1 markers were analyzed in 576 trios, consisting of 141 ADHD + CD and 435 ADHD - CD. In addition to the classical TDT test, a specific genetic heterogeneity test was performed to identi…
Neuroprotective Effects of Low Intensity and Low Frequency Electromagnetic �in vitro� Stimulation on Glial Cells
2020
Degenerative neurological diseases (senile dementia, Alzheimer`s disease, glaucoma), post-stroke sequelae are increasing as prevalence nowadays, in context of aging in general population, and there are strong evidences that astrocytes may play a significant role in neuroprotection. The study evaluates the effects of low intensity low frequency electromagnetic field (EMF) �in vitro� stimulation (195 mA, 7-8 Hz) on the glial cells, in different conditions, in order to identify the neuroprotective potential. Three cell lines were used for the study: the Clonetics (Lonza) line of normal human astrocytes, U87 glioblastoma tumor cells (ATCC) and L929 murine fibroblasts. The cell cultures were ex…
Integration of local features into a global shape
2001
AbstractIt is a well-established fact that the cortical filters selective for spatial frequency and orientation have a limited spatial extent. The present study investigated how information from local filters is integrated into global shapes. Specifically, we were interested in whether identification of a global pattern consisting of small oriented, spatially-bandpass features (Gabor patches) depends on the orientations of those features. The observer was presented with a C-like stimulus shape comprised of oriented Gabor elements on a blank background, and the performance measure was the threshold contrast for identifying the global orientation of the C-shape (four possible rotated orientat…
The effect of resonance frequency breathing when used as a preparatory exercise in music psychotherapy : A single-case experimental study of a client…
2017
This study aimed at evaluating the possible benefits of starting Integrative Improvisational Music Therapy (IIMT) sessions with 10 min of Resonance Frequency Breathing (RFB), a type of slow breathing known to be beneficial for stress reduction and emotional regulation. A client diagnosed with anxiety disorder and social phobia attended 12 IIMT sessions. Using an alternating treatments design, RFB was systematically alternated with a control intervention (vibroacoustic therapy, VAT). Therapy processes were assessed through the Session Evaluation Questionnaire (SEQ) and the continuous measurement of heart rate variability (HRV), a biomarker of autonomic nervous system response. RFB was consis…
A powerful thyristor modulator for a microtron
1980
Abstract The circuit of a powerful modulator is illustrated and a detailed description is given of the modulator construction and in particular of the components employed. The main parameters are: length of shaped pulse 2 μs; amplitude of the output voltage 30 kV; pulse repetition frequency 50–200 Hz. The compactness of this device, its comparatively low cost and its good performance, as illustrated in the attached photographs, make it suitable for use in accelerator engineering (microtron).
Sub-200-kHz single soliton generation in a long ring Er-fiber laser with strict polarization control by using twisted fiber
2020
Abstract In the present work we demonstrate a novel single-soliton ultra-low pulse repetition frequency passively mode-locked erbium-doped fiber laser. We mitigate the residual linear birefringence of fiber by fiber twist to achieve a strict control of polarization. For mode-locking the nonlinear polarization rotation (NPR) was used. Special technique was applied to reduce the overdriving of NPR that allows the generation of single soliton in ultra-long cavity. The strict control of polarization yields a stable relation between the polarization state of the pulses propagating in the cavity and the regimes of generation. A 192.12-kHz train of soliton pulses was obtained with pulse duration o…
Assessment of a Modified Acoustic Lens for Electromagnetic Shock Wave Lithotripters in a Swine Model
2013
The acoustic lens of the Modularis electromagnetic shock wave lithotripter (Siemens, Malvern, Pennsylvania) was modified to produce a pressure waveform and focal zone more closely resembling that of the original HM3 device (Dornier Medtech, Wessling, Germany). We assessed the newly designed acoustic lens in vivo in an animal model.Stone fragmentation and tissue injury produced by the original and modified lenses of the Modularis lithotripter were evaluated in a swine model under equivalent acoustic pulse energy (about 45 mJ) at 1 Hz pulse repetition frequency. Stone fragmentation was determined by the weight percent of stone fragments less than 2 mm. To assess tissue injury, shock wave trea…
Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022.
1999
The oxidative DNA damage induced by the polar photosensitizer Ro19-8022 in the presence of light was studied and correlated with the associated mutagenicity. Both in isolated DNA and AS52 Chinese hamster ovary cells, photoexcited Ro19-8022 gave rise to a DNA damage profile that was similar to that caused by singlet oxygen: base modifications sensitive to the repair endonuclease Fpg protein, which according to high-performance liquid chromatography (HPLC) analysis were predominantly 8-hydroxyguanine (8-oxoG) residues, were generated in much higher yield than single-strand breaks, sites of base loss (AP sites) and oxidative pyrimidine modifications sensitive to endonuclease III. Fifty percent…