Search results for " fungus"

showing 10 items of 43 documents

Presence of nucleosomes inPenicillium chrysogenum

1987

We have studied the chromatin structure ofPenicillium chrysogenum. This fungus presents the typical nucleosomal repeat and the core DNA size characteristic of all the eukaryotes. The repeat length (about 180 base pairs) is in the range of those obtained for most fungi (160–180 base pairs) and shorter than in higher eukaryotes. Knowledge aboutP. chrysogenum chromatin structure opens the way to the study of the mechanisms of genetic regulation in this filamentous fungus.

GeneticsBase pairGeneral MedicineFungusFungi imperfectiBiologybiology.organism_classificationPenicillium chrysogenumApplied Microbiology and BiotechnologyMicrobiologyChromatinFilamentous funguschemistry.chemical_compoundchemistryBiochemistryNucleosomeDNACurrent Microbiology
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A Major Effect Gene Controlling Development and Pathogenicity in Botrytis cinerea Identified Through Genetic Analysis of Natural Mycelial Non-pathoge…

2021

Botrytis cinerea is a necrotrophic plant pathogenic fungus with a wide host range. Its natural populations are phenotypically and genetically very diverse. A survey of B. cinerea isolates causing gray mold in the vineyards of Castilla y León, Spain, was carried out and as a result eight non-pathogenic natural variants were identified. Phenotypically these isolates belong to two groups. The first group consists of seven isolates displaying a characteristic mycelial morphotype, which do not sporulate and is unable to produce sclerotia. The second group includes one isolate, which sporulates profusely and does not produce sclerotia. All of them are unresponsive to light. Crosses between a repr…

Geneticsgray moldBulked segregant analysisLocus (genetics)bulked segregant analysiPlant SciencePathogenic fungusBiologylcsh:Plant cultureacetyl transferasebiology.organism_classificationGenetic analysisLaboratorium voor PhytopathologieDNA binding domainComplementationbulked segregant analysisLaboratory of Phytopathologygenetic complementationlcsh:SB1-1110AlleleEPSGeneBotrytis cinereaOriginal ResearchFrontiers in Plant Science
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Different effectors of dimorphism in Yarrowia lipolytica

2002

Yarrowia lipolytica is an ascomycete with biotechnological potential. In common media, the fungus grows as a mixture of yeast-like and short mycelial cells. The environmental factors that affect dimorphism in the wild-type strain, W29, and its auxotrophic derivative, PO1a, were analyzed. In both strains, pH was the most important factor regulating the dimorphic transition. Mycelium formation was maximal at pH near neutrality and decreased as pH was lowered to become almost null at pH 3. Carbon and nitrogen sources, namely glucose and ammonium, were also important for mycelium formation; and their effect was antagonized by some alternative carbon and nitrogen sources. Citrate was an importan…

Hot TemperatureNitrogenAuxotrophyYarrowiaFungusBiochemistryMicrobiologyCitric Acidchemistry.chemical_compoundBotanyCyclic AMPMorphogenesisGeneticsAmmoniumMolecular BiologyMyceliumSex CharacteristicsbiologyEffectorfungiYarrowiaGeneral MedicineHydrogen-Ion Concentrationbiology.organism_classificationCarbonYeastCulture MediaBiochemistrychemistryStarvationDimorphic fungusArchives of Microbiology
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Growth and macromolecular content of the dimorphic fungus Aureobasidium pullulans and the effect of hydroxyurea and other inhibitors

1988

The growth kinetics and the macromolecular content of the yeast and ethanol-induced hyphal forms of Aureobasidium pullulans were studied. During the morphological transition from yeasts to hyphae, both the protein and RNA content decreased significantly, the mycelial form containing only 76% of the amount of protein in the yeasts, and 38% of the RNA. The DNA was the only component tested whose level increased during the transition. Among several compounds inhibiting macromolecular synthesis, only hydroxyurea showed a remarkable effect on the morphology of A. pullulans, inducing the mycelial morphology. The macromolecular composition of hydroxyurea-treated cultures changed with time in a way…

HyphaPolysorbatesBiologyMicrobiologyMicrobiologyFungal Proteinschemistry.chemical_compoundHydroxyureaDNA FungalMolecular BiologyMyceliumEthanolRNARNA FungalGeneral MedicineFungi imperfectibiology.organism_classificationYeastCulture MediaQuaternary Ammonium CompoundsAureobasidium pullulansKineticsGlucoseBiochemistrychemistryMitosporic FungiDimorphic fungusDNAAntonie van Leeuwenhoek
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A comparison of the transcriptome of Drosophila melanogaster in response to entomopathogenic fungus, ionizing radiation, starvation and cold shock

2015

Background The molecular mechanisms that determine the organism's response to a variety of doses and modalities of stress factors are not well understood. Results We studied effects of ionizing radiation (144, 360 and 864 Gy), entomopathogenic fungus (10 and 100 CFU), starvation (16 h), and cold shock (+4, 0 and -4°C) on an organism's viability indicators (survival and locomotor activity) and transcriptome changes in the Drosophila melanogaster model. All stress factors but cold shock resulted in a decrease of lifespan proportional to the dose of treatment. However, stress-factors affected locomotor activity without correlation with lifespan. Our data revealed both significant similarities …

Ionizing radiationSurvivalTranscriptomeRadiation IonizingCellular stress responseGene expressionGeneticsmedicineAnimalsOrganismGeneticsCold shockLifespanbiologyResearchCold-Shock ResponseEntomopathogenic fungusFungibiology.organism_classificationCold shock responseCell biologyDrosophila melanogasterStarvationShock (circulatory)Entomopathogenic fungusGene expressionDrosophila melanogastermedicine.symptomTranscriptomeBiotechnologyBMC Genomics
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Drought-induced positive feedback in xylophagous insects: Easier invasion of Scots pine leading to greater investment in immunity of emerging individ…

2012

Abstract We studied the infestation rate of Scots pine Pinus sylvestris by xylophagous insects in relation to distance from forest lakes in eastern Latvia, northern Europe. In summers of 2008 and 2009, we felled 72 pines of approximately 65 years age. Sections of the logs were incubated in insect emergence traps. The trees located near lakes were significantly less infested by xylophagous insects than those sampled at greater distances from the lakes. We also tested the ability of Tomicus piniperda , the most abundant species of xylophagous insects in our samples, to resist the entomopathogenic fungus Beauveria bassiana . The results show that beetles captured near lakes were more susceptib…

LarvaEcologymedia_common.quotation_subjectta1172fungiScots pinefood and beveragesBeauveria bassianaForestryInsectManagement Monitoring Policy and LawBiologymedicine.disease_causebiology.organism_classificationTomicus piniperdavisual_artparasitic diseasesInfestationEntomopathogenic fungusvisual_art.visual_art_mediummedicineta1181BarkNature and Landscape Conservationmedia_commonForest Ecology and Management
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Sesquiterpenoids from the Endophytic Fungus Rhinocladiella similis

2019

Ten new sesquiterpenoid derivatives, rhinomilisins A-J (1-10), along with six known analogues (11-16), were isolated from the mangrove-derived endophytic fungus Rhinocladiella similis. The structures of the new compounds were elucidated by their NMR and MS data, while the absolute configuration of 3 and 6 was determined by X-ray crystallographic analysis and Mosher's method, respectively. All isolated compounds (1-16) were evaluated for their cytotoxicity against the mouse lymphoma cell line L5178Y, and compounds 1, 7, and 15 showed moderate activity with IC50 values of 5.0, 8.7, and 24.4 μM, respectively.

Magnetic Resonance SpectroscopyStereochemistryPharmaceutical ScienceModerate activityCrystallography X-Ray01 natural sciencesAnalytical ChemistryMiceAscomycotaDrug DiscoveryEndophytesIc50 valuesAnimalsCytotoxicityPharmacology010405 organic chemistryChemistryMouse LymphomaOrganic ChemistryAbsolute configurationNuclear magnetic resonance spectroscopyEndophytic fungus0104 chemical sciences010404 medicinal & biomolecular chemistryComplementary and alternative medicineRhinocladiella similisMolecular MedicineSesquiterpenesJournal of Natural Products
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Farinomalein derivatives from an unidentified endophytic fungus isolated from the mangrove plant Avicennia marina

2012

Five farinomalein derivatives including three new compounds, farinomaleins C–E (3–5), and one new isoindoline congener (6) were isolated from an unidentified endophytic fungus obtained from the inner tissues of healthy leaves of the mangrove plant Avicennia marina from Oman. The structures of the new compounds were unambiguously elucidated on the basis of their mass, as well as one and two dimensional NMR spectroscopic data.

Mangrove plantsbiologyChemistryOrganic ChemistryIsoindolineEndophytic fungusbiology.organism_classificationBiochemistryAvicenniachemistry.chemical_compoundCongenerAvicennia marinaDrug DiscoveryBotanyMangroveFarinomaleinTetrahedron Letters
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Polyketide Derivatives from Mangrove Derived Endophytic Fungus Pseudopestalotiopsis theae

2020

Chemical investigation of secondary metabolites from the endophytic fungus Pseudopestalotiopsis theae led to the isolation of eighteen new polyketide derivatives, pestalotheols I&ndash

Models MolecularMagnetic Resonance SpectroscopyStereochemistryPharmaceutical Science010402 general chemistry01 natural sciencesArticlePolyketidepolyketideDrug DiscoverymedicineEndophytesCytotoxicityPharmacology Toxicology and Pharmaceutics (miscellaneous)IC50lcsh:QH301-705.5endophytic fungusbiologyMolecular Structure010405 organic chemistryChemistryAbsolute configurationFungibiology.organism_classification0104 chemical sciencesAcinetobacter baumanniiPseudopestalotiopsis theaelcsh:Biology (General)<i>Pseudopestalotiopsis theae</i>PolyketidesFermentationColistincytotoxicityRhizophoraceaeAntibacterial activityTwo-dimensional nuclear magnetic resonance spectroscopymedicine.drugMarine Drugs
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Biology, cultivation, and medicinal functions of the mushroom Hericium erinaceum

2016

&lt;em&gt;Hericium erinaceum&lt;/em&gt; (Bull.: Fr.) Pers. is an edible fungus of great significance in medicine. It is rarely found in Europe, in contrast, it is common in Japan and North America. Its fruitbodies have been well-known for hundreds of years in traditional Chinese medicine and cuisine. A cradle of &lt;em&gt;H. erinaceum&lt;/em&gt; cultivation is Asia. In Eastern Europe is rare in natural habitats, but can be successfully cultivated. Both fruitbodies and mycelia are rich in active, health promoting substances. Tests of substances extracted from this mushroom carried out on animals and in vitro have given good results. They can be used in the treatment of cancer, hepatic disord…

Mushroommedicinebioactive compoundsTraditional medicineHericium erinaceumQuality of sleepfungiPlant ScienceTraditional Chinese medicineEdible fungusBiologyBioactive compoundHericium erinaceumchemistry.chemical_compoundchemistrycultivationlcsh:Biology (General)lcsh:QH301-705.5Ecology Evolution Behavior and SystematicsMyceliumHepatic disordersHericium erinaceum; cultivation; medicine; bioactive compoundsActa Mycologica
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