Search results for " graft"

showing 10 items of 262 documents

Is COVID‐19 infection more severe in kidney transplant recipients?

2021

International audience; There are no studies which have compared the risk of severe Covid-19 and related mortality between transplant recipients and non-transplant patients. We enrolled two groups of patients hospitalized for Covid-19, i.e., kidney transplant recipients from the French Registry of Solid Organ Transplant (n=306) and a single-center cohort of non-transplant patients (n=795). An analysis was performed among subgroups matched for age and risk factors for severe Covid-19 or mortality. Severe Covid-19 was defined as admission (or transfer) to an intensive care unit, need for mechanical ventilation, or death.Transplant recipients were younger and had more comorbidities compared to…

medicine.medical_treatment[SDV]Life Sciences [q-bio]MESH: Registries*AucunMESH: Comorbidity030230 surgerylaw.inventionchemistry.chemical_compound0302 clinical medicinelawcardiovascular diseaseMESH: Risk Factors[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesclinical research / practiceImmunology and AllergyCumulative incidencePharmacology (medical)kidney transplantation / nephrologyMESH: IncidenceMESH: AgedUnivariate analysisMESH: France / epidemiologyMESH: Middle AgedMESH: Transplant Recipients / statistics & numerical data*Acute kidney injuryIntensive care unit3. Good healthMESH: COVID-19 / epidemiologyCohort[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseasesglomerular filtration rate (GFR)kidney failure / injurymedicine.medical_specialtyinfection and infectious agents - viralinfectious diseaseBrief CommunicationMESH: Graft Rejection / prevention & control03 medical and health sciencesInternal medicineDiabetes mellitusMESH: Severity of Illness IndexMESH: COVID-19 / diagnosis*medicineHumansMESH: SARS-CoV-2Mechanical ventilationCreatinineTransplantationMESH: Humansbusiness.industrySARS-CoV-2MESH: Graft Rejection / epidemiology*COVID-19MESH: Retrospective Studiesmedicine.diseaseKidney TransplantationTransplant RecipientsMESH: Maleimmunosuppressive regimensMESH: Immunosuppressive Agents / therapeutic useMESH: Pandemics*MESH: Propensity Score*chemistryReinfectionMESH: Immunosuppression / methodsMESH: Intensive Care UnitsbusinessMESH: FemaleMESH: Kidney Transplantation*
researchProduct

Nonunion and malunion in proximal humerus fractures

2020

Proximal humerus fractures are common injuries and the development of nonunion or malunion is infrequent. However, these complications can occur with both operative and non-operative treatment of the fracture. A complete evaluation of these patients must include an investigation of the original fracture, bone and soft tissue quality as well as an extensive radiological study with X-Ray, CT and MRI. Asymptomatic and low demanding patients can benefit from conservative treatment, otherwise surgery is necessary. Multiple treatment options exist with no consensus upon the gold standard. The management of these complications is case-specific and needs extensive pre-operative planning. Arthroscop…

musculoskeletal diseases030222 orthopedicsmedicine.medical_specialtyShoulder FractureJoint replacementbusiness.industrymedicine.medical_treatmentRotator cuff injuryNonunion030229 sport sciencesBone graftingmedicine.diseaseArthroplastySurgery03 medical and health sciencesPseudarthrosis0302 clinical medicinemedicineMalunionbusinessLo Scalpello - Otodi Educational
researchProduct

Cementless acetabular reconstruction and structural bone-grafting in dysplastic hips. Surgical technique.

2007

BACKGROUND: Studies of acetabular reconstruction with use of cement and bulk bone graft have demonstrated increasing rates of cup failure in patients with dysplastic hips seven years after total hip arthroplasty. Comparable data on the long-term results of bulk bone-grafting done in conjunction with cementless implants are limited. The aim of this study was to review the clinical and radiographic results of autologous bulk bone-grafting in conjunction with a cementless cup. METHODS: From 1987 to 1992, forty-seven patients (forty women and seven men, with an average age of 50.4 years) who had developmental dysplasia of the hip underwent fifty-six total hip arthroplasties and received a struc…

musculoskeletal diseasesMaleReoperationmedicine.medical_specialtyRadiographymedicine.medical_treatmentBone graftingTransplantation AutologousArthroplastymedicineHip DislocationHumansOrthopedics and Sports MedicineProspective StudiesSurvival rateHip dysplasiaBone Transplantationbusiness.industryAcetabulumGeneral MedicineMiddle Agedmedicine.diseaseAcetabulumSurgeryProsthesis FailureTransplantationRadiographysurgical procedures operativeTreatment OutcomeOrthopedic surgerySurgeryFemaleImplantHip ProsthesisbusinessThe Journal of bone and joint surgery. American volume
researchProduct

MRI evaluation to predict tendon size for knee ligament reconstruction.

2017

Background The aim of this study is to evaluate a possible correlation between specific anthropometric parameters and sizes of knee tendons commonly used for ACL reconstruction. We hypothesized that specific clinical and radiological knee measurements could be better tendon sizes predictors than age, gender, height and weight. Materials and methods 100 consecutive patients were enrolled and 77 patients met the inclusion criteria of the study. All patients underwent a MRI of the knee with a 1.5 T super conducting MR System. For each patient, anthropometric data such as gender, height, weight, body mass index (BMI) and knee circumference were recorded. Specific MRI knee measurements were perf…

musculoskeletal diseasesOrthodontics030222 orthopedicsbusiness.industry05 social sciences050801 communication & media studiesmusculoskeletal systemCircumferenceTendon03 medical and health sciences0508 media and communications0302 clinical medicinemedicine.anatomical_structureGracilis tendonKnee ligamentquadriceps tendon autograft patellar tendon autograft acl reconstruction mri graft size measurement preoperative measures hamstringmedicineOrthopedics and Sports MedicinePatellaOriginal ArticleQuadriceps tendonbusinessBody mass indexHamstringMuscles, ligaments and tendons journal
researchProduct

Evaluation of efficacy and biocompatibility of a new absorbable synthetic substitute as a dural onlay graft in a large animal model.

2016

Numerous dura substitutes are commercially available, but no absorbable synthetic dura repair product has been used for both onlay and suture applications.The safety and effectiveness of a new absorbable synthetic substitute composed of Poly-L-lactide microfibers as onlay dural graft were evaluated.Physical properties and performance of the microfibrous synthetic dural substitute implanted as an onlay or suturable grafts were compared with these commercial products, including CODMAN ETHISORB™ Dura Patch and DuraGen™ Dural Graft Matrix, in a canine duraplasty model. The cerebrospinal fluid (CSF) leakage, macroscopic and microscopic observation at 30 and 90 days after implantation were invest…

musculoskeletal diseasesmedicine.medical_specialtyTime FactorsBiocompatibilityPolyesters02 engineering and technologyDural graftIn Vitro Techniques03 medical and health sciences0302 clinical medicineDogsDural substitutemedicineAnimalsCsf leakageCerebrospinal Fluid Leakbusiness.industryGeneral Medicine021001 nanoscience & nanotechnologynervous system diseasesSurgeryMicroscopic observationDisease Models AnimalNeurologyInlaysNeurology (clinical)Dura Mater0210 nano-technologybusiness030217 neurology & neurosurgeryLarge animalNeurological research
researchProduct

Treatment of Combined Medial and Lateral Collateral Ligament Insufficiency

2016

The medial and lateral collateral ligament complexes represent primary elbow ligament stabilizers. Injury to these structures may occur because of an elbow dislocation or due to a severe varus or valgus force. Most elbow dislocations are stable once reduced and may be treated conservatively. However, if the elbow remains unstable surgical treatment is recommended. Repair should be anatomical and should restore stability to the elbow in order to permit an early active range of motion. Reconstruction may be required in severe cases and where primary repair is not possible. Depending on the degree of instability, either one or both of the collateral ligament complexes may need to be repaired o…

musculoskeletal diseasesmedicine.medical_specialtybiologybusiness.industryElbowmusculoskeletal systembiology.organism_classificationSurgerybody regionsValgusPrimary repairmedicine.anatomical_structureElbow dislocationelbow instability elbow ligament reconstruction circumferential graft reconstructionSettore MED/33 - Malattie Apparato LocomotoreLigamentMedicinebusinessSurgical treatmentRange of motion
researchProduct

Cirurgia coronària amb i sense circulació extracorpòria. Morbimortalitat postoperatòria i seguretat a curt i llarg terme

2016

OBJETIUS: Les malalties cardiovasculars representen el 25-40% de totes les morts a Europa i Amèrica del Nord amb una majoria causada per coronariopaties. La cirurgia de revascularització coronària amb circulació extracorpòria (CEC) segueix sent el “gold stàndard” del tractament quirúrugic d’aquesta patologia. Malgrat la millora de les tècniques i l'experiència quirúrgica, part de la morbiditat relacionada amb la cirurgia coronària és causada per la CEC i és per aquest motiu l’augment de procediments de revascularització coronària sense CEC les darreres dècades. L’ objectiu d’aquesta tesi és descriure l’experiència del nostre centre durant 20 anys (1993-2013) en la cirurgia cardiaca de revas…

on pumpcoronary artery bypass graftoff pumpoutcomessurvival
researchProduct

Hetero-difunctional dimers as building blocks for the synthesis of poly(amidoamine)s with hetero-difunctional chain terminals and their derivatives

2012

This article reports on a simple and straightforward preparation method of poly(amidoamine)s (PAAs) with hetero-difunctional chain ends as well as of several up to now hardly obtainable PAA derivatives of biotechnological interest, such as for instance PAAs of controlled molecular weight and narrow polydispersity mono-functionalized at one end with an acrylamide group, PAAs with star-like molecular architecture, graft-PAA-protein conjugates, “tadpole-like” PAA conjugates with hydrophobic moieties able to self assemble into nanoparticles in aqueous media. The key step was to design suitable building blocks consisting of hetero-difunctional dimers (HDDs). In particular, the HDDs considered we…

poly(amidoamine)Materials Chemistry2506 Metals and AlloyPolymers and PlasticPolymers and PlasticsChemistrynanoparticleOrganic ChemistryAmidoamineDispersityamphiphileNanoparticlePoly(amidoamine)star polymerchemistry.chemical_compoundChain (algebraic topology)PolymerizationpolyamineAmphiphilePolymer chemistryMaterials Chemistryprotein graftingConjugateJournal of Polymer Science Part A: Polymer Chemistry
researchProduct

Grafting of polymer chains on the surface of carbon nanotubes via nitroxide radical coupling reaction

2016

Poly(butylene succinate)/MWCNTs nanocomposites with improved dispersion and with nanotubes embedded/immobilized into the polymer matrix were here prepared by an alternative "grafting to" method based on thenitroxide radical coupling reaction. Poly(butylene succinate) (PBS) was grafted on the surface of TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxy) modified multi-walled carbon nanotubes (MWCNTs) via a nitroxide radical coupling reaction. TEMPO functionalized MWCNTs (MWCNTs-g-TEMPO) were synthesized using the Cu(I)-catalyzed azide/alkyne click chemistry approach and the covalent bond of the nitroxide moieties onto the MWCNTs was confirmed via electron paramagnetic resonance (EPR) spectroscopy.…

polymer grafting; MWCNTs; nitroxide radical coupling (NRC); click chemistry; electron paramagnetic resonance (EPR); rheologyPolymers and PlasticsClick chemistryElectron paramagnetic resonance (EPR)MWCNTNitroxide radical coupling (NRC)RheologyPolymer grafting
researchProduct

Pirmreizējas sirds ritma izmaiņas pacientiem pēc atvērtās sirds operācijas

2019

Pēcoperācijas ātriju fibrilācija (POĀF) ir biežākā komplikācija pacientiem, kuriem veikta operācija uz atvērtas sirds. Kā rezultātā tā ietekmē morbiditāti, mortalitāti, kā arī palielina finansiālas izmaksas. Pētījuma mērķis ir uzzināt vai ir korelācija starp veiktiem pirms operācijas standarta izmeklējuma rezultātiem un pēcoperācijas ātriju fibrilāciju. Jo nosakot augsta riska pacientu var uzsākt preventīvu ārstēšanu. Materiāli un metodes: retrospektīvs pētījums, kur tika iekļauti pacienti, kam veikta sirds operācija ar sternotomijas pieeju, kuriem pirms operācijas bija sīnusa ritms n = 111. 39 pacienti netika iekļauti pētījumā, jo pirms operācijas bija ātriju fibrilācija vai anamnēzē ātrij…

postoperative atrial fibrillationcoronary artery bypass graftingpredictors of postoperative atrial fibrillationcardiopulmonary bypassMedicīna
researchProduct