Search results for " growth"
showing 10 items of 4263 documents
The rodent tibia fracture model: A critical review and comparison with the complex regional pain syndrome literature
2018
Abstract Distal limb fracture is the most common cause of complex regional pain syndrome (CRPS), thus the rodent tibia fracture model (TFM) was developed to study CRPS pathogenesis. This comprehensive review summarizes the published TFM research and compares these experimental results with the CRPS literature. The TFM generated spontaneous and evoked pain behaviors, inflammatory symptoms (edema, warmth), and trophic changes (skin thickening, osteoporosis) resembling symptoms in early CRPS. Neuropeptides, inflammatory cytokines, and nerve growth factor (NGF) have been linked to pain behaviors, inflammation, and trophic changes in the TFM model and proliferating keratinocytes were identified …
Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regeneration 1
2001
SPECIFIC AIMSWe have studied the molecular mechanisms and mediators behind the induction of methionine adenosyltransferase 2 A (MAT2A) gene expression in the regenerating rat liver after partial he...
Frequency of polymorphisms of signal peptide of TGF-beta1 and -1082G/A SNP at the promoter region of Il-10 gene in patients with carotid stenosis
2006
The role of inflammation in atherosclerosis is well recognized. We have evaluated the allele frequencies of the +869T/C and +915G/C polymorphisms (SNPs) at the TGF-beta1 gene and -1082G/A SNP at IL-10 promoter sequence, two well-known immunosuppressive and anti-inflammatory cytokines, in patients with carotid stenosis. Our data suggest a lack of association between these SNPs and the susceptibility to atherosclerosis although other reports have demonstrated this association. These results may be due to the pleiotropic effects of the cytokines and/or differences in haplotype combination that should be investigated to elucidate the role of TGF-beta1 and IL-10 polymorphisms in atherosclerosis.
Mast cell growth-enhancing activity (MEA) is structurally related and functionally identical to the novel mouse T cell growth factor P40/TCGFIII (int…
1990
We have previously shown that certain bone marrow-derived mast cell (BMMC) lines proliferate in response to a mast cell growth-enhancing activity (MEA) that is distinct from interleukin (IL) 3 and IL 4. Here we provide evidence that MEA is identical with the recently cloned mouse T cell growth factor P40. The evidence is as follows: (a) recombinant P40 displayed all the biological activities ascribed to MEA: it supported the growth of MEA-sensitive BMMC lines, it induced IL 6 secretion by these cells, and it enhanced survival of primary mast cell cultures; (b) highly purified MEA stimulated the growth of P40-dependent cell lines; (c) a rabbit monospecific antiserum directed against P40 spec…
Stem Cell Therapy
2019
The necessity of improving the health and quality of life of subjects affected by diverse injuries and chronic diseases, has led to develop a new branch of translational medicine, called Regenerative Medicine (RegMed). RegMed has the principal objects of restoring, maintaining or enhancing structures and functions of tissues and organs. In order to achieve these goals, the RegMed researchers have proposed and tested diverse approaches. The Stem Cell Therapy represents the central focus of RegMed, even if its applications may imply the onset of adverse conditions. Here, an overview of this topic will be reported, by pointing advantages and disadvantages.
Fractal investigation of the buit-up area in metropolitan areas, of transportation networks and of the urban growth
1994
International audience
Stepping up to strike: a union mobilization case study of Polish migrant workers in the Netherlands
2015
This article examines a union mobilization of Polish temporary agency workers in the Netherlands. The case study contributes to the migrant organizing literature a micro-level account of the dynamics of mobilization from the viewpoint of the migrants and organizers involved. The findings emphasize the importance of key actors in building solidarities within and between different groups of workers in fragmented workplaces, with implications for unions seeking new ways to respond to changing employment practices. This study highlights some of the possibilities and limitations of organizing among contractually fragmented workforces.
The division of domestic work among dual-career and other dual-earner couples in Finland
2015
This study compares the division of domestic work among dual-career and other dual-earner couples. We examine whether gender attitudes, relative resources and working time explain the differences between dual-career and other dual-earner couples. We define dual-career couples as those in which both spouses are professionals and/or managers. The division of housework is important for these couples because of the intense pressures of work. We hypothesise that domestic work is more equally shared among dual-career couples than among other dual-earner couples. The quantitative analyses are based on the Finnish data from the 2010 European Social Survey (N = 493). The qualitative data consist of …
A model for predicting the mixed-mode fatigue crack growth in a bonded joint
2013
Bonded joints are highly sensitive to the presence of defects and to the degradation phenomena, and this aspect represents the primary obstacle to their use in different structural engineering applications. Delamination in a bonded joint represents, in fact, one of the primary, most common and insidious causes of damage. In this paper, a numerical–experimental study on the crack propagation along the adhesive layer of a bonded joint specimen is carried out. Experimental study is focused on the evaluation of the damage modalities of a bonded joint when the specimens are subject to fatigue load. Experimental tests are compared with the results of several numerical analysis performed in ANSYS …
A new aid modality for Africa
2013
Preprint of an article published in the Journal of Economic Policy Reform with the title:“Stimulating economic growth in the least developed countries: Direct cash transfers for the retired via mobile phones,” The result of current aid policies is that only a small percentage of foreign aid reaches the poorest of the poor in the least developed countries. Current trends of urbanisation and self-reliance place elderly people in an increasingly difficult situation. This paper aims to stimulate debate by introducing an alternative mechanism for foreign aid. With the help of an economic model, we demonstrate how direct cash transfers to elderly people can spur economic growth. Targeting all eld…