Search results for " hyperactivity"

A polygenic approach to the association between smoking and schizophrenia.

2021

Smoking prevalence in schizophrenia is considerably larger than in general population, playing an important role in early mortality. We compared the polygenic contribution to smoking in schizophrenic patients and controls to assess if genetic factors may explain the different prevalence. Polygenic risk scores (PRSs) for smoking initiation and four genetically correlated traits were calculated in 1108 schizophrenic patients (64.4% smokers) and 1584 controls (31.1% smokers). PRSs for smoking initiation, educational attainment, body mass index and age at first birth were associated with smoking in patients and controls, explaining a similar percentage of variance in both groups. Attention-defi…

Clinical Recognition and Management of Adult Attention Deficit Hyperactivity Disorder

1996

Adults with attention deficit disorder (ADD) and attention deficit hyperactivity disorder (ADHD) are a new phenomenon to many health care providers. While increasing evidence indicates children with ADD/ADHD can have persistent problems into adulthood, the significance and management of these disorders for adults are poorly understood. Studies of adults are confounded by frequent comorbidity with other conditions and by retrospective diagnosis of childhood ADD/ADHD. Research studies of pharmacologic interventions do not indicate a clear pattern of efficacy and safety for any drug class. Pharmacologic treatment of adults with ADD/ADHD is often guided by clinical experience. Efficacy of treat…

Types of Adult Attention-Deficit/Hyperactivity Disorder: A Replication Analysis.

2019

OBJECTIVE Research supports the importance of emotional symptoms in adults with attention-deficit/hyperactivity disorder (ADHD), which are not reflected in the DSM-5 or ICD-10 criteria. The Wender-Reimherr Adult Attention Deficit Disorder Scale (WRAADDS) assesses these symptoms, plus inattention, hyperactivity, and impulsivity. This scale allowed us to divide adult ADHD into 2 subtypes in a 2015 publication: ADHD inattentive presentation and ADHD emotional dysregulation presentation. The present study refines this observation using a larger, more diverse sample. METHODS Eight double-blind adult ADHD clinical trials (encompassing 1,490 subjects) were selected because they included assessment…

Association of Cesarean Delivery With Risk of Neurodevelopmental and Psychiatric Disorders in the Offspring: A Systematic Review and Meta-analysis.

2019

This systematic review and meta-analysis examines the association between birth by cesarean delivery and risk of neurodevelopmental and psychiatric disorders in the offspring compared with birth by vaginal delivery.

Women with borderline personality disorder do not show altered BOLD responses during response inhibition.

2015

Impulsivity is central to borderline personality disorder (BPD). Response inhibition, addressing the ability to suppress or stop actions, is one aspect of behavioral impulse control which is frequently used to assess impulsivity. BPD patients display deficits in response inhibition under stress condition or negative emotions. We assessed whether response inhibition and its neural underpinnings are impaired in BPD when tested in an emotionally neutral setting and when co-morbid attention-deficit/hyperactivity disorder (ADHD) is excluded. To this end, we studied response inhibition in unmedicated BPD patients and healthy controls (HC) in two independent samples using functional magnetic reson…

2021

The cell—cell signaling gene CDH13 is associated with a wide spectrum of neuropsychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD), autism, and major depression. CDH13 regulates axonal outgrowth and synapse formation, substantiating its relevance for neurodevelopmental processes. Several studies support the influence of CDH13 on personality traits, behavior, and executive functions. However, evidence for functional effects of common gene variation in the CDH13 gene in humans is sparse. Therefore, we tested for association of a functional intronic CDH13 SNP rs2199430 with ADHD in a sample of 998 adult patients and 884 healthy controls. The Big Five personality tra…

Individual Differences in Personality Associated with Aggressive Behavior among Adolescents Referred for Externalizing Behavior Problems

2017

The present study examined the extent to which individual differences in personality that have been previously associated with aggression in non-clinical subjects (Caprara et al., European Journal of Personality, 27(3), 290–303, 2013, Caprara et al., Developmental Psychology, 50(1), 71–85, 2014) account for aggression among adolescents referred to psychiatric services with diagnosis within the externalizing spectrum (i.e., conduct disorder, oppositional defiant disorder, and attention deficit hyperactivity disorder). In particular a conceptual model was examined in which individual differences in basic traits (i.e., emotional instability and agreeableness), lower order traits (i.e., irritab…

Comorbilidad de TEA y TDAH: revisión sistemática de los avances en investigación

2016

La reciente publicación del DSM-5, introduce la novedad de aceptar la posibilidad de un diagnóstico comórbido de los Trastorno de Espectro Autista (TEA) y el Trastorno por Déficit de Aten- ción/Hiperactividad (TDAH). En este artículo se realiza una revisión de trabajos que han estudiado esta comorbilidad. Se revisaron un total de 28 investigaciones, estableciendo 4 temáticas diferentes. La investigación muestra tasas variables de comorbili- dad de TEA y TDAH dependiendo de la edad y procedencia de las mues- tras, y de los criterios diagnósticos empleados. Cuando se da la comorbili- dad de TEA y TDAH aumenta la severidad de la sintomatología autista y de trastornos externalizantes e internal…

Voices behind and beyond the label : the master narrative of ADHD (de)constructed by diagnosed children and their parents

2016

Artikkeliväitöskirja. Sisältää yhteenveto-osan ja neljä artikkelia. Article dissertation. Contains an introduction part and four articles. The dominant understanding of attention deficit hyperactivity disorder (ADHD) is that of diagnosed children “suffering” from neurodevelopmental condition owing to which they are prone to develop adverse life trajectories. This master narrative of ADHD and psychomedical and normative discourses it adheres to and employs have been integrated into the daily activities of homes and schools. This compilation dissertation study employs a social constructionist discourse framework and is located in the intersection of the disciplines of disability studies and s…

Neuropsychological Profile, Emotional/Behavioral Problems, and Parental Stress in Children with Neurodevelopmental Disorders

2021

Background: The aim of our study was to trace a specific neuropsychological profile, to investigate emotional-behavioral problems and parental stress in children with Autism Spectrum Disorder Level 1/High functioning (ASD-HF), Specific Learning Disorders (SLD) and Attention Deficit/Hyperactivity Disorder (ADHD) disorders and to highlight similarities and differences among the three groups. Methods: We retrospectively collected the data from a total of 62 subjects with ASD-HF (n = 19) ADHD (n = 21), SLD (n = 22) and 20 typical development. All the participants underwent neuropsychological standardized test for the evaluation of cognitive profile (Wechsler Intelligence Scale for Children Four…