Search results for " impr"

La partecipazione ad un business ecosystem: implicazioni per la nozione di successo

2020

L’obiettivo del capitolo è offrire un’introduzione alla letteratura sugli ecosistemi aziendali e discutere critica-mente la tematica del successo e della misurazione delle performance del business ecosystem e degli attori che vi partecipano. A tale scopo, il capitolo è strutturato come segue. Il paragrafo 2 focalizza l’attenzione sulla definizione di business ecosystem. I paragrafi 3, 4 e 5 spiegano, rispettivamente, perché nasce un business ecosystem, chi sono gli attori e quali sono le strutture sottese agli ecosistemi aziendali. Il paragrafo 6 discute la misurazione delle performance del business ecosystem focalizzando l’attenzione sui seguenti aspetti: (a) indicatori di performance a li…

DSC AND TGA TO EVALUATE THE SELECTIVE IMPREGNATION OF WATERLOGGED ARCHAEOLOGICAL WOODS WITH POLY(ETHYLENE) GLYCOLS MIXTURES

2012

Within the cultural heritage field the wood conservation of waterlogged archaeological objects aims at preventing the collapsing of the wooden structure (upon drying) the degradation of which is related to the Taxon but also to the chemical and biological nature of the site. The refilling of the wood cavities with a consolidant, which confers robustness and stability, is an interesting strategy for the conservation methods of waterlogged archaeological objects. To this purpose, using different impregnation methods, waterlogged archaeological woods were consolidated by using aqueous mixtures of poly(ethylene) glycols with different molecular weights (PEG 400 and PEG 4000) as well as mixtures…

Aberrations of Genomic Imprinting in Glioblastoma Formation

2021

In human glioblastoma (GBM), the presence of a small population of cells with stem cell characteristics, the glioma stem cells (GSCs), has been described. These cells have GBM potential and are responsible for the origin of the tumors. However, whether GSCs originate from normal neural stem cells (NSCs) as a consequence of genetic and epigenetic changes and/or dedifferentiation from somatic cells remains to be investigated. Genomic imprinting is an epigenetic marking process that causes genes to be expressed depending on their parental origin. The dysregulation of the imprinting pattern or the loss of genomic imprinting (LOI) have been described in different tumors including GBM, being one …

Stochastic Loss of Silencing of the Imprinted Ndn/NDN Allele, in a Mouse Model and Humans with Prader-Willi Syndrome, Has Functional Consequences

2013

Genomic imprinting is a process that causes genes to be expressed from one allele only according to parental origin, the other allele being silent. Diseases can arise when the normally active alleles are not expressed. In this context, low level of expression of the normally silent alleles has been considered as genetic noise although such expression has never been further studied. Prader-Willi Syndrome (PWS) is a neurodevelopmental disease involving imprinted genes, including NDN, which are only expressed from the paternally inherited allele, with the maternally inherited allele silent. We present the first in-depth study of the low expression of a normally silent imprinted allele, in path…

Divergently Transcribed Overlapping Genes Expressed in Liver and Kidney and Located in the 11p15.5 Imprinted Domain

1998

Human chromosomal band 11p15.5 has been shown to contain genes involved in the development of several pediatric and adult tumors and in Beckwith-Wiedemann syndrome (BWS). Overlapping P1 artificial chromosome clones from this region have been used as templates for genomic sequencing in an effort to identify candidate genes for these disorders. PowerBLAST identified several matches with expressed sequence tags (ESTs) from fetal brain and liver cDNA libraries. Northern blot analysis indicated that two of the genes identified by these ESTs encode transcripts of 1-1.5 kb with predominant expression in fetal and adult liver and kidney. With RT-PCR and RACE, full-length transcripts were isolated f…

Application of molecularly imprinted polymers in analytical chiral separations and analysis

2018

Over the last two decades the process of development and application of a new types of molecular imprinted polymer (MIP) sorbents in the field of analytical chemistry have been widely described in the literature. One of the new trends in analytical chemistry practice is the use of new types of MIP sorbents as specific sorption materials constituting the stationary phase in advanced separation techniques. The following review paper contains comprehensive information about the application of a specific and well defined MIP sorbents (with the data base in the paper about the reagents used in MIP preparation process) as stationary phases in separation techniques including high performance liqui…

Recent Advances in Sample Preparation for Pesticide Analysis

2012

Much progress has been made in pesticide analysis in the past decade. During this time, hyphenated techniques involving highly efficient separation with sensitive mass spectrometric detection have become the methods of choice. Even with such powerful instrumental techniques, a demanding task in pesticide residue analysis is the development of multiresidue methods for the determination of pesticides in air, water, soil, sediment, biota, and food. This chapter summarizes the analytical characteristics of the different methods of sample preparation for the determination of pesticide residues in a variety of food matrices, and surveys their recent applications in combination with gas chromatogr…

Capitale sociale e produttività nelle province italiane: un approccio multilivello

2014

Collaborare per crescere. La cooperazione tra imprese al Nord e al Sud

2014

Dove si diffonde un sistema di relazioni cooperative, le imprese sperimentano una più elevata crescita economica, entrano con maggiore successo nei mercati internazionali, realizzano innovazioni che si diffondono rapidamente sui mercati. Queste tendenze sono state spesso richiamate soprattutto in questi anni di grave crisi economica e vengono confermate anche dal Rapporto della Fondazione RES 2013 curato da Pier Francesco Asso e Emmanuele Pavolini. Ma a che cosa è legata la propensione delle imprese a cooperare? Perché la collaborazione è così "difficile"? Esistono differenze territoriali importanti che distinguono le imprese del Sud da quelle del Nord? Quali sono le attitudini a collaborar…

Fiducia, Partecipazione a reti e performance economica

2014

Nell'ambito di una ricerca originale su un campione rappresentativo di imprese operanti in un numero selezionato di settori, è stato analizzato il ruolo della fiducia interpersonale e della fiducia istituzionale nel determinare una maggiore o minore propensione a collaborare; inoltre è stata approfondita la relazione fra partecipazione a reti (formali e informali) e performance economica, distinguendo anche il caso in cui le reti sono il risultato di legami forti di tipo parentale o amicale