Search results for " injury"

showing 10 items of 1007 documents

Quality changes in fresh-cut mango cubes submitted to different gas partial pressure of active MAPs

2018

The study was performed to assess chemical-physical and sensory quality changes in 4±1°C stored fresh-cut mangos and to test the effect of active modified atmosphere packaging (MAP) with different gas partial pressures. Sicilian fruits of ‘Keitt’ mango (Mangifera indica L.) were immerged in hydrogen peroxide (H2O2) after being peeled. Next, the flesh was cut in cubes and dipped in citric acid (0.5%, w/v) and ascorbic acid (0.5%, w/v). Treated fruits were placed in a non-perforated high density polyethylene package flushing different gas mixtures and kept at 4°C for 21 days. We used four different gas partial pressures: a) 60 kPa N2, 30 kPa CO2 and 10 kPa O2; b) 30 kPa CO2 and 70 kPa N2; c) …

Settore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticultureSoluble solidsSettore BIO/10 - BiochimicaCrop qualitymodified atmosphere packaging Mangifera indica ‘Keitt’ respiration rate colorChilling injuryPartial pressureHorticultureAscorbic acidMathematics
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Effects of 1-MCP on post harvest quality and internal browning of white-flesh loquat fruit during cold storage

2017

Introduction – Treatments with 1-methylcyclopropene (1-MCP), an inhibitor of ethylene perception, were investigated on white-flesh loquat fruit to extend its shelf life and to prevent chilling injury. Ma- terials and methods – The loquat (Eriobotrya japonica Lindl.) white-flesh fruits (cv. Claudia) were submitted to applications of 1-MCP at 1 °C for 20 h and at concentrations from 1 to 5 μL L . The treated fruits were stored at 1 °C for 21 days before removal to 20 °C for ripening (shelf life). Fruit quality was analyzed at harvest, at the end of each storage period (7, 14, 21 days at 1 °C). Results and discussion - The 1-MCP treatment slowed fruit softening depending on concentration, and …

Settore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeSettore AGR/15 - Scienze E Tecnologie AlimentariItaly loquat Eriobotrya japonica 1-methylcyclopropene chilling injury fruit firmness phenolics shelf life
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Effects of 1-Methylcyclopropene on post harvest quality of white flesh loquat (Eriobotrya japonica Lindl.) fruit.

2014

Settore AGR/03 - Arboricoltura Generale E Coltivazioni Arboreeantioxidant capacitu chilling injury ethylene polyphenols ripening softening.
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The effect of Betanin parenteral pretreatment on Jejunal and pulmonary tissue histological architecture and inflammatory response after Jejunal ische…

2019

Intestinal ischemic-reperfusion (IR) injury has detrimental effects on both local and distant organs in the body. Betanin is known for its antioxidant properties, and it is found mostly in vegetables. Therefore, the aim of the present study was to test the hypothesis that betanin administration prior intestinal IR, may be beneficial in protecting jejunal mucosa and lung parenchyma against IR damage. Male specific pathogen-free Charles River Wistar rats were used (n = 42). Betanin (50 mg/kg) was administered intraperitoneally 30 min before ischemia of the superior mesenteric artery lasting 1 h, followed by 1, 4 and 24 h of reperfusion. Immunohistochemical as well as histomorphometrical analy…

Settore BIO/17 - IstologiaMale0301 basic medicineParenteral NutritionClinical BiochemistryWistarIschemiaIschemia-reperfusion injuryPharmacologyBetaninMast cellPathology and Forensic MedicineJejunum03 medical and health scienceschemistry.chemical_compound0302 clinical medicineIntestinal mucosaLung injury indexmedicine.arteryParenchymamedicineAnimalsSuperior mesenteric arteryRats WistarLungMolecular BiologyBetaninInflammationMyeloperoxidasebiologybusiness.industrymedicine.diseaseRats3. Good healthJejunum030104 developmental biologymedicine.anatomical_structurechemistryReperfusion Injury030220 oncology & carcinogenesisMyeloperoxidasebiology.proteinBetacyaninsbusinessMucosal injury indexReperfusion injuryExperimental and Molecular Pathology
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Memory function after resolution of post traumatic amnesia

2005

Primary objectives: The aims of this pilot study were (1) to examine neuropsychological, particularly memory functions immediately after post-traumatic amnesia (PTA) resolution according to the Galveston Orientation and Amnesia Test (GOAT), and (2) to provide a preliminary exploration of pattern of performance on GOAT items across PTA duration. Methods and procedures: Thirty-seven head injured patients were administered the Recognition Memory Tests on the day that PTA resolved. Formal neuropsychological assessment was conducted on average 10 days after PTA resolution. Main outcomes and results: All the patients in the series showed memory impairment which varied in severity but was typicall…

Settore M-PSI/02 - Psicobiologia E Psicologia FisiologicaPost-traumatic amnesia memory traumatic brain injury
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Liver and Statins: A Critical Appraisal of the Evidence.

2019

Adverse drug reactions (ADRs) represent an important cause of morbidity and mortality worldwide. Statins are a class of drugs whose main adverse effects are drug-induced liver injury (DILI) and myopathy. Some of these may be predictable, due to their pharmacokinetic and pharmacodynamic properties, while others, unfortunately, are idiosyncratic. Genetic factors may also influence patient susceptibility to DILI and myopathy in the case of statins. This review will first discuss the role of statins in cardiovascular disease treatment and prevention and the underlying mechanisms of action. Furthermore, to explore the susceptibility of statin-induced adverse events such as myopathy and hepatoto…

Settore MED/09 - Medicina InternaOrganic Anion TransportersGenome-wide association studyBioinformaticsBiochemistryCytochrome P-450 Enzyme SystemHLA AntigensDrug DiscoveryMetSmedicineHumansGenetic Predisposition to DiseaseDrug reactionMyopathyAdverse effectDisease treatmentPharmacologybusiness.industryOrganic ChemistryStatinmedicine.diseaseHepatitis CHCV.Critical appraisalSingle Nucleotide Polymorphisms (SNPs)Cardiovascular DiseasesPharmacodynamicsliver damageMolecular MedicineATP-Binding Cassette TransportersMetabolic syndromemedicine.symptomChemical and Drug Induced Liver InjuryHydroxymethylglutaryl-CoA Reductase Inhibitorsbusinessgenetic susceptibilityCurrent medicinal chemistry
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Studies of selective TNF inhibitors in the treatment of brain injury from stroke and trauma: a review of the evidence to date

2014

Antonino Tuttolomondo, Rosaria Pecoraro, Antonio Pinto Biomedical Department of Internal and Specialistic Medicine, University of Palermo, Palermo, Italy Abstract: The brain is very actively involved in immune-inflammatory processes, and the response to several trigger factors such as trauma, hemorrhage, or ischemia causes the release of active inflammatory substances such as cytokines, which are the basis of second-level damage. During brain ischemia and after brain trauma, the intrinsic inflammatory mechanisms of the brain, as well as those of the blood, are mediated by leukocytes that communicate with each other through cytokines. A neuroinflammatory cascade has been reported to be activ…

Settore MED/09 - Medicina InternaTraumatic brain injurytumor necrosis factor inhibitorsCentral nervous systemIschemiaPharmaceutical ScienceReviewAMPA receptorEtanerceptBrain ischemiaTBIDrug DiscoverymedicineAnimalsHumansStroke trauma TNF-alfa antagonistPharmacologyMicrogliaTumor Necrosis Factor-alphabusiness.industrytraumatic brain injurylcsh:RM1-950Anti-Inflammatory Agents Non-Steroidalbrain injurymedicine.diseaseStrokelcsh:Therapeutics. Pharmacologymedicine.anatomical_structureBrain InjuriesImmunologyTumor necrosis factor alphabusinessmedicine.drugDrug Design, Development and Therapy
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Hyperuricemia is associated with histological liver damage in patients with non-alcoholic fatty liver disease.

2011

Background Hyperuricemia has been associated with metabolic disorders. In this line recent studies observed an independent link between higher uric acid serum levels and clinical diagnosis of non-alcoholic fatty liver disease (NAFLD). Aims We aimed to assess the potential association between uric acid serum levels and histological liver damage in a homogeneous cohort of biopsy-proven NAFLD patients. Methods Consecutive NAFLD patients (n = 166), assessed by liver biopsy (Kleiner score), anthropometric, biochemical and metabolic features, were included. Enzymatic colorimetric test was used for serum uric acid assays (Roche Diagnostics GmbH, Mannheim, Germany). Hyperuricemia was diagnosed when…

Settore MED/12 - Gastroenterologialiver fibrosinonalcoholic fatty liverSettore MED/08 - Anatomia Patologicaliver biopsyuric acid nafld hyperuricemialiver injury
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G.F.R. measuring with 99mTc-DTPA: limits in obstructive acute renal failure.

1991

After a short introduction on the advantages and limits of G.F.R. determination with Ccr, the radioisotopic methods proposed by Schlegel and Gates for this parameter are described, and as well as ERPF and FF, without blood serial samples being necessary. In a severe renal failure case due to obstruction, the Authors have found a great mismatch in the results between the traditional methods and the radioisotopic ones. After the clinical case description, a possible explanation of this discrepancy is proposed: Schlegel and Gates' methods, which well correlate Ccr in chronic renal failure cases, in severe renal failure on obstructive basis, of recent onset, could not indicate the effective glo…

Settore MED/14 - NefrologiaSettore MED/09 - Medicina InternaAcute Kidney Injury/physiopathology* Female Glomerular Filtration Rate* Humans Middle Aged Technetium Tc 99m Pentetate/diagnostic use*HumansTechnetium Tc 99m PentetateFemaleAcute Kidney InjuryMiddle AgedSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheGlomerular Filtration RatePanminerva medica
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Neuroprotective properties of xenon and helium in an in vitro model of traumatic brain injury: one small step or one big jump?

2008

Settore MED/27 - Neurochirurgiabusiness.industryTraumatic brain injurychemistry.chemical_elementCritical Care and Intensive Care Medicinemedicine.diseaseNeuroprotectionXenum helium neuroprotectionIn vitro modelXenonchemistryAnesthesiaJumpMedicinebusinessAnesthetics; Inhalation; administration /&/ dosage/therapeutic use Animals Brain Injuries; prevention /&/ control Disease Models; Animal Helium; administration /&/ dosage/therapeutic use Mice Mice; Inbred C57BL Tissue Culture Techniques Xenon; administration /&/ dosage/therapeutic use
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