Search results for " latency"
showing 10 items of 65 documents
Scoring Criteria for Electrodermal Habituation: Further Research
1988
In the context of Levinson and Edelberg's critique of scoring criteria for electrodermal habituation, the present study examined the question of whether trials-to-habituation scores based on two no-response trials are superior to scores based on three no-response trials. Male students (N=120) performed two identical habituation experiments on two consecutive days and their skin conductance responses based on a short latency window of 1–3 s were analyzed. In each experiment subjects received 20 presentations of a 1000 Hz tone at 65dB. Results showed that three-trials scores were higher overall and that the distributions of three- and two-trials scores differed. On the other hand, the twoscor…
Portable PSG for sleep stage monitoring in sports: Assessment of SOMNOwatch plus EEG.
2019
Current sport-scientific studies mostly neglect the assessment of sleep architecture, although the distribution of different sleep stages is considered an essential component influencing an athlete's recovery and performance capabilities. A mobile, self-applied tool like the SOMNOwatch plus EEG might serve as an economical and time-friendly alternative to activity-based devices. However, self-application of SOMNOwatch plus EEG has not been validated against conventional polysomnography (PSG) yet. For evaluation purposes, 25 participants (15 female, 10 male;
Cognitive behavioral therapy for shift workers with chronic insomnia
2012
Abstract Objective Shift work is a challenge in the screening and treatment of chronic insomnia. The aim of this study was to examine the implementation and effectiveness of a cognitive behavioral group intervention for insomnia (CBT-I) among shift workers with chronic insomnia. We also studied whether insomnia symptoms and intervention effects differed on work days and days off. Methods The study design was a non-randomized group intervention, including a waiting period prior to CBT-I as a control condition. A total of 19 media workers who worked irregular hours and had non-organic insomnia with features of psychological insomnia completed the study. We followed up with the results for a p…
Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell “Memory Inflation” and Avoid Immune Evasion
2021
Acute infection with murine cytomegalovirus (mCMV) is controlled by CD8+ T cells and develops into a state of latent infection, referred to as latency, which is defined by lifelong maintenance of viral genomes but absence of infectious virus in latently infected cell types. Latency is associated with an increase in numbers of viral epitope-specific CD8+ T cells over time, a phenomenon known as “memory inflation” (MI). The “inflationary” subset of CD8+ T cells has been phenotyped as KLRG1+CD62L- effector-memory T cells (iTEM). It is agreed upon that proliferation of iTEM requires repeated episodes of antigen presentation, which implies that antigen-encoding viral genes must be transcribed du…
Completeness and timeliness: Cancer registries could/should improve their performance.
2015
Abstract Cancer registries must provide complete and reliable incidence information with the shortest possible delay for use in studies such as comparability, clustering, cancer in the elderly and adequacy of cancer surveillance. Methods of varying complexity are available to registries for monitoring completeness and timeliness. We wished to know which methods are currently in use among cancer registries, and to compare the results of our findings to those of a survey carried out in 2006. Methods In the framework of the EUROCOURSE project, and to prepare cancer registries for participation in the ERA-net scheme, we launched a survey on the methods used to assess completeness, and also on t…
PV-Alert: A fog-based architecture for safeguarding vulnerable road users
2017
International audience; High volumes of pedestrians, cyclists and other vulnerable road users (VRUs) have much higher casualty rates per mile; not surprising given their lack of protection from an accident. In order to alleviate the problem, sensing capabilities of smartphones can be used to detect, warn and safeguard these road users. In this research we propose an infrastructure-less fog-based architecture named PV-Alert (Pedestrian-Vehicle Alert) where fog nodes process delay sensitive data obtained from smartphones for alerting pedestrians and drivers before sending the data to the cloud for further analysis. Fog computing is considered in developing the architecture since it is an emer…
Effect of Six-Month Diet Intervention on Sleep among Overweight and Obese Men with Chronic Insomnia Symptoms : A Randomized Controlled Trial
2016
Growing evidence suggests that diet alteration affects sleep, but this has not yet been studied in adults with insomnia symptoms. We aimed to determine the effect of a six-month diet intervention on sleep among overweight and obese (Body mass index, BMI >= 25 kg/m(2)) men with chronic insomnia symptoms. Forty-nine men aged 30-65 years with chronic insomnia symptoms were randomized into diet (n = 28) or control (n = 21) groups. The diet group underwent a six-month individualized diet intervention with three face-to-face counseling sessions and online supervision 1-3 times per week; 300-500 kcal/day less energy intake and optimized nutrient composition were recommended. Controls were instruct…
Adaptative Network Topology for Data Centers
2016
Data centers have an important role in supporting cloud computing services (such as email, social networking, web search, etc.) enterprise computing needs, and infrastructure-based services. Data center networking is a research topic that aims at improving the overall performances of the data centers. It is a topic of high interest and importance for both academia and industry. Several architectures such as FatTree, FiConn, DCel, BCube, and SprintNet have been proposed. However, these topologies try to improve the scalability without any concerns about energy that data centers use and the network infrastructure cost, which are critical parameters that impact the performances of data centers…
Role for Tumor Necrosis Factor Alpha in Murine Cytomegalovirus Transcriptional Reactivation in Latently Infected Lungs
2004
ABSTRACT Interstitial pneumonia is a major clinical manifestation of primary or recurrent cytomegalovirus (CMV) infection in immunocompromised recipients of a bone marrow transplant. In a murine model, lungs were identified as a prominent site of CMV latency and recurrence. Pulmonary latency of murine CMV is characterized by high viral genome burden and a low incidence of variegated immediate-early (IE) gene expression, reflecting a sporadic activity of the major IE promoters (MIEPs) and enhancer. The enhancer-flanking promoters MIEP1/3 and MIEP2 are switched on and off during latency in a ratio of ∼2:1. MIEP1/3 latency-associated activity generates the IE1 transcript of the ie1/3 transcrip…
Patchwork Pattern of Transcriptional Reactivation in the Lungs Indicates Sequential Checkpoints in the Transition from Murine Cytomegalovirus Latency…
1999
The lungs are a relevant organ site of primary and recurrent human cytomegalovirus (hCMV) disease (for overviews, see references 21, 22, 31, 34, 39, and 44). Murine CMV (mCMV) can serve us as a model for studying CMV pneumonia in acute infection (6, 27, 33, 37) as well as for studying viral latency, reactivation, and recurrence in the lungs (2, 17, 18, 42, 43). We have shown recently that transcription from the major immediate-early (MIE) transcription unit ie1-ie3 (hereafter referred to as ie1/3), which is driven by a strong MIE promoter-enhancer (MIEPE) (3), occurs during pulmonary latency of mCMV but fails to initiate the productive cycle (17). Notably, the paralogous MIEPE of hCMV can f…